This classic text, one of the true anchors of our clinical genetics publishing program, covers over 700 different genetic syndromes involving the head and neck, and it has established itself as the definitive, comprehensive work on the subject. The discussion covers the phenotype spectrum, epidemiology, mode of inheritance, pathogenesis, and clinical profile of each condition, all of which is accompanied by a wealth of illustrations. The authors are recognized leaders in the field, and their vast knowledge and strong clinical judgment will help readers make sense of this complex and burgeoning field. Dr. Gorlin retires as editor in this edition and co-editor Raoul Hennekam takes over. Dr. Hennekam is regarded as one of the top dysmorphologists--and indeed one of the top clinical geneticists--in the world. Judith Allanson is new to the book but is a veteran OUP author and a widely respected geneticist, and Ian Krantz at Penn is a rising star in the field. Dr. Gorlin's name has always been closely associated with the book, and it has now become part of the title. As in all fields of genetics, there has been an explosion in the genetics of dysmorphology syndromes, and the author has undertaken a complete updating of all chapters in light of the discoveries of the Human Genome Project and other ongoing advances, with some chapters requiring complete rewriting. Additional material has been added both in terms of new syndromes and in updating information on existing syndromes. The book will appeal to clinical geneticists, pediatricians, neurologists, head and neck surgeons, otolarynologists, and dentists. The 4th edition, which published in 2001, has sold 2,600 copies.
The Performer's Voice, Second Edition presents a comprehensive approach to the prevention, diagnosis, and treatment of voice disorders as well as up-to-date voice care and injury prevention information--specifically related to actors, singers, and other voice professionals. This second edition is completely updated with six new chapters and contributions from leading voice professionals. Written in an accessible, straightforward style, The Performer's Voice, Second Editionappeals to medical professionals, vocal coaches, and professional performers. This text not only serves as an effective resource for practitioners and clinicians who provide state-of-the-art treatment to voice professionals, but also provides professional vocalists and coaches with insight into what to look for when seeking treatment. The authors have dedicated their careers to voice disorders and prevention of voice injury as well as education and research to advance the science and art of voice care. The diversity of authors' backgrounds supports the importance of a multidisciplinary approach in the care of voice disorders.
On every continent and in every nation, animals unrecognized by modern science are reported on a daily basis. People passionately pursue these creatures--the name given to their field of study is cryptozoology. Coined in the 1950s, the term literally means the science of hidden animals. When the International Society of Cryptozoology (ISC) was formed in 1982, the founders declared that the branch of science is also concerned with "the possible existence of known animals in areas where they are not supposed to occur (either now or in the past) as well as the unknown persistence of presumed extinct animals to the present time or to the recent past...what makes an animal of interest to cryptology is that it is unexpected." This reference work presents a "flesh and blood" view of cryptozoology. Here, 2,744 entries are listed, the majority of which each describe one specific creature or type of creature. Other entries cover 742 places where unnamed cryptids are said to appear; profiles of 77 groups and 112 individuals who have contributed to the field; descriptions of objects and events important to the subject; and essays on cryptotourism and hoaxes, for example. Appendices offer a timeline of zoological discoveries, annotated lists of movies and television series with cryptozoological themes, a list of crypto-fiction titles and a list of Internet websites devoted to cryptozoology.
Comprehensive and highly detailed, Twomey on Partnership, 2nd edition, includes practitioner-focused chapters on disputes between partners, litigation by and against partnerships and a commentary on each of the clauses of a typical partnership agreement. Few areas of law are as similar throughout the common law world as partnership law. This important book analyses not only Irish, English and Scottish partnership cases, but also the rich vein of partnership cases to be found in other common law jurisdictions, and explains how these cases impact upon Irish law. This new edition has been updated to take account of key Irish cases over the last 17 years, including McAleenan v AIG, Harris v Quigley and Cronin v Kehoe. In addition, it includes analysis of any foreign (particularly English) cases of particular relevance. A new chapter has been added which deals with the Legal Services Regulation Act 2015 and its provisions on partnerships, including limited liability partnerships. While the key partnership acts (the Partnership Act 1890, the Limited Partnerships Act 1907 and the Investment Limited Partnerships Act 1994) have not changed to any significant degree since publication of the first edition, the Irish Government has approved changes to the Investment Limited Partnerships Act 1994 and this is dealt with in the book. Other analysis of legislation in the book has been been updated to reflect the changes since the first edition, in particular the material relating to Companies Act 2014.
This thoroughly researched study highlights the international community's failure to regulate contemporary state research, development, marketing and/or deployment of riot control agents and incapacitating chemical agent weapons.
Michael Kelly's writing is driven by love of his native Liverpool, which reaches back to his ancestral Ireland. In this collection of short biographies, Michael becomes the friend of his subjects, rather than a mere researcher. He writes of them because he is one of them, an Irish Liverpudlian in the grand old tradition.
A Primary Source. This birth register is a primary genealogy source for finding the location and relative number of Irish families in 19th century Ireland. (Most families remain centered in the same areas in Ireland).This is an enlarged print out of the birth index of Ireland. It lists every surname found, and the county it was found in. Larger print makes it easier to read than the original. We have added a map of the counties and provinces along with commentary. Research aid published by the Irish Genealogical Foundation. One of the very few sources we have to locate surnames for the genealogy researcher in 19th century Ireland. This work serves as an Irish census records substitute for locating traditional family names in Ireland. If you do not know where to start looking for death, marriage and land records, this family surname locator could help find your county of origin.
This is the first systematic study of modern China's military campaigns and the actual fighting conducted by the People's Liberation Army since the founding of the People's Republic. It provides a general overview of the evolution of PLA military doctrine, and then focuses on major combat episodes from the civil war with the Nationalists to the last significant combat in Vietnam in 1979, in addition to navy and air operations through 1999. In contrast to the many works on the specifics and hardware of China's military modernization, this book discusses such topics as military planning, command, and control; fighting and politics; combat tactics and performance; technological catch-up and doctrinal flexibility; the role of Mao Zedong; scale and typologies of fighting; and deterrence. The contributors include scholars from Mainland China, Taiwan, and the United States, who draw from a wealth of fresh archival sources.
Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease. Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy. The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimer's dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.
For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. A new volume in this trusted series, Diabetes Secrets offers practical, up-to-date coverage of the full range of essential topics in this dynamic field. It features the Secrets' popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style – making inquiry, reference, and review quick, easy, and enjoyable. - The proven Secrets Series® format gives you the most return for your time – succinct, easy to read, engaging, and highly effective. - Up-to-date coverage of the full range of topics in diabetes, including diabetes during pregnancy; diabetes management in cancer patients; diabetes management during exercise, sports, and competition; diabetes management in hospitalized patients, and more. - Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams. - Bulleted lists, mnemonics, practical tips from global leaders in the field – all providing a concise overview of important board-relevant content. - Written by global experts and thought leaders in diabetes. - Portable size makes it easy to carry with you for quick reference or review anywhere, anytime.
With this new 6th Edition, Exercise Physiology for Health, Fitness, and Performance continues to provide an authoritative resource for mastering exercise physiology. This engaging, accessible and approachable resource integrates theoretical and research-based basic exercise physiology with real-world application to prepare students for exciting positions in exercise science, fitness, physical education, athletic training, rehabilitation, coaching, and/or allied health professions. Updated throughout, the text uses sound pedagogical principles to explain scientific research that is the foundation of exercise physiology and incorporates multiple features to help students apply their knowledge to improve human health, fitness, and performance. Content in this edition is organized by independent units (Metabolic, Cardiovascular-Respiratory, Neuromuscular-Skeletal, and Neuroendocrine-Immune), offering maximum teaching flexibility for faculty and ensuring a consistent, efficient, and effective learning experience for students.
Each type of performer, whether singer, voice-over artists, dancer/singers, instrumentalist/singers, brings specific issues to the voice treatment team and requires special individual attention from the various members of the team, from laryngologist to speech pathologist, singing or voice teacher. The Singer's Voice identifies these individuals, presents reports on cases with special needs and offers myriad solutions that help to preserve the voice and prevent further damage. It is written by a world-leading group of dedicated professionals from an array of disciplines related to the care and treatment of individuals who use their voices in professional settings. Ranging from current day performers to choral conductors to past rock and roll musicians, all contributors have shown a dedication to the care of the singer and performer through their studios, academic training, their research interests and experience, and their clinical and/or their performance background. The content is thoroughly practical and written to be accessible to a wide range of voice professionals, particularly singing and voice teachers; instructors in the various performing arts; those who provide medical and allied health care; and, indeed, performers and students themselves.
This unique multidisciplinary 8-volume set focuses on the emerging issues concerning synthesis, characterization, design, manufacturing and various other aspects of composite materials from renewable materials and provides a shared platform for both researcher and industry. The Handbook of Composites from Renewable Materials comprises a set of 8 individual volumes that brings an interdisciplinary perspective to accomplish a more detailed understanding of the interplay between the synthesis, structure, characterization, processing, applications and performance of these advanced materials. The Handbook comprises 169 chapters from world renowned experts covering a multitude of natural polymers/ reinforcement/ fillers and biodegradable materials. Volume 5 is solely focused on 'Biodegradable Materials'. Some of the important topics include but not limited to: Rice husk and its composites; biodegradable composites based on thermoplastic starch and talc nanoparticles; recent progress in biocomposites of biodegradable polymer; microbial polyesters: production and market; biodegradable and bioabsorbable materials for osteosynthesis applications; biodegradable polymers in tissue engineering; composites based on hydroxyapatite and biodegradable polylactide; biodegradable composites; development of membranes from biobased materials and their applications; green biodegradable composites based on natural fibers; fully biodegradable all-cellulose composites; natural fiber composites with bioderivative and/or degradable polymers; synthetic biodegradable polymers for bone tissue engineering; polysaccharides as green biodegradable platforms for building up electroactive composite materials; biodegradable polymer blends and composites from seaweeds; biocomposites scaffolds derived from renewable resources for bone tissue repair; pectin-based composites; recent advances in conductive composites based on biodegradable polymers for regenerative medicine applications; biosynthesis of PHAs and their biomedical applications; biodegradable soy protein isolate/poly(vinyl alcohol) packaging films; and biodegradability of biobased polymeric materials in natural environment.
This is the first systematic study of modern China's military campaigns and the actual fighting conducted by the People's Liberation Army since the founding of the People's Republic. It provides a general overview of the evolution of PLA military doctrine, and then focuses on major combat episodes from the civil war with the Nationalists to the last significant combat in Vietnam in 1979, in addition to navy and air operations through 1999. In contrast to the many works on the specifics and hardware of China's military modernization, this book discusses such topics as military planning, command, and control; fighting and politics; combat tactics and performance; technological catch-up and doctrinal flexibility; the role of Mao Zedong; scale and typologies of fighting; and deterrence. The contributors include scholars from Mainland China, Taiwan, and the United States, who draw from a wealth of fresh archival sources.
Today we are politically polarized as never before. The presidential elections of 2000 and 2004 will be remembered as two of the most contentious political events in American history. Yet despite the recent election upheaval, The American Voter Revisited discovers that voter behavior has been remarkably consistent over the last half century. And if the authors are correct in their predictions, 2008 will show just how reliably the American voter weighs in, election after election. The American Voter Revisited re-creates the outstanding 1960 classic The American Voter---which was based on the presidential elections of 1952 and 1956---following the same format, theory, and mode of analysis as the original. In this new volume, the authors test the ideas and methods of the original against presidential election surveys from 2000 and 2004. Surprisingly, the contemporary American voter is found to behave politically much like voters of the 1950s. "Simply essential. For generations, serious students of American politics have kept The American Voter right on their desk. Now, everyone will keep The American Voter Revisited right next to it." ---Larry J. Sabato, Director of the University of Virginia Center for Politics and author of A More Perfect Constitution "The American Voter Revisited is destined to be the definitive volume on American electoral behavior for decades. It is a timely book for 2008, with in-depth analyses of the 2000 and 2004 elections updating and extending the findings of the original The American Voter. It is also quite accessible, making it ideal for graduate students as well as advanced undergrads." ---Andrew E. Smith, Director of the University of New Hampshire Survey Center "A theoretically faithful, empirically innovative, comprehensive update of the original classic." ---Sam Popkin, Professor of Political Science, University of California, San Diego Michael S. Lewis-Beck is F. Wendell Miller Distinguished Professor of Political Science at the University of Iowa. William G. Jacoby is Professor of Political Science at Michigan State University. Helmut Norpoth is Professor of Political Science at Stony Brook University. Herbert F. Weisberg is Professor of Political Science at Ohio State University.
The gigantic size of polymer molecules makes them "viscoelastic": their behavior changes depending on how fast and for how long the material is used. This book describes the latest discoveries in the field from a fundamental molecular perspective, in order to guide the development of better and new applications for soft materials.
Finally, a multi-disciplinary approach that covers both the surgical and non-surgical interventions for sleep apnea and snoring. From the editor of Operative Techniques in Otolaryngology, this new reference will quickly become the standard in surgery for this key area within otolaryngology. ., Full-color line drawings illustrate key concepts and create a comprehensive way of learning surgical techniques. Provides consistent, templated chapters and a contemporary, full-color format for quick, easy access to the most up-to-date surgical and non surgical interventions for sleep apnea and snoring. Includes contributions from leaders in neurology, pulmonology, psychiatry, otolaryngology, and oral & maxillofacial surgery. to create a truly multi-disciplinary approach. Covers new and innovative procedures including ZPP (Zeta palatopharyngoplasty), Transpalatal Advancement Pharyngoplasty and Minimally invasive submucosal glossectomy Details when and why surgery is necessary, and how to perform a successful operation for snoring and sleep apnea.
This book invites readers into Tolkien’s world through the lens of a variety of philosophers, all of whom owe a rich debt to the Neoplatonic philosophical tradition. It places Tolkien’s mythology against a wider backdrop of Catholic philosophy and asks serious questions about the nature of creation, the nature of God, what it means to be good, and the problem of evil. Halsall sets Tolkien alongside both his contemporaries and ancient authors, revealing his careful use of literary devices inspired by them to craft his own “mythology for England.”
A breakthrough therapy in the mental health field, Rebuilding Therapy was developed by psychologist Michael Gass, primarily, as a means of assisting individuals and families in rebuilding psychologically from past mistreatment, dysfunction, or trauma. It incorporates methodology, techniques, and theory from Psychodrama, a vital part of Rebuilding Therapy, while integrating Transactional Analysis, primarily Structural Analysis and the influence of Script Analysis, and Redecision Therapy to create its distinctive theoretical foundations, methods, and approaches. Relaxation exercises or relaxation, which is equivalent to hypnosis, is used as needed. Rebuilding Therapy is based on the belief that a person is basically the product of his or her past. Its primary focus is for the patient to clinically relive major abusive, rejecting, traumatic, or negative life experiences in order to face unhealthy feelings, thinking, and decisions associated with them, which the patient can then release, change, and rebuild from. In addition to postbirth experiences, Rebuilding Therapy pays attention to prenatal influences and the birth process, regarding their effect on psychological functioning and personality development, while also addressing these factors therapeutically. Rebuilding Therapy also has the methodology to solely work with present issues as needed. In the first book on this reconstructive therapy, Gass details its theoretical foundations, methodology, and approaches to acquaint mental health and related professionals with its value on a short and long term basis; to expand on the understanding of personality development and psychological functioning; and to further expose this and related psychotherapies for use in other arenas on the local, state, and international levels in such areas as law enforcement, corrections, education, religion, business, politics, and international relations, with the aim of reducing conflict and inappropriate behavior and improving human relationships.
This book examines the two chief anatomical and physiological embodi-ment theories of voluntary animal motion, which I call the cardiosinew and cerebroneuromuscular theories of motion, from the time of Aristotle (384-322 B.C.) to that of Mondino (d. A.D. 1326). The study of animal motion commenced with the ancient Greek natural scientist Aristotle who wrote the monograph 'On the motion of animals' (De motu animalium). Subsequent inquiries into voluntary animal motion may be found in a variety of Greek, Latin, and Arabic compendia, commentaries, and encyclopedias throughout the ancient and medieval periods. The motion of animals was considered relevant to natural philosophers and theologians investigating the nature of the soul, and to physicians seeking to discover the causes of disorders of voluntary movement such as epilepsy and tetany. The book fills a gap in the scholarly literature concerned with pre-modern studies of the anatomical and physiological mechanisms of will and bodily movement. The accompanying photographs of my own anatomical dissections illuminate ancient and medieval conceptual, empirical, and experimental methods of anatomical and physiological research.
This is a collection of essays written by Moore which form a thorough examination of the theory of criminal responsibility. The author covers a wide range of topics, giving the book a coherence and unity which is rare in assembled essays. Perhaps the most significant feature of this book isMoore's espousal of a retributivist theory of punishment. This anti-utilitarian standpoint is a common thread throughout the book. It is also a trend which is currently manifesting itself in all areas of moral, political and legal philosophy, but Moore is one of the first to apply such attitudes sosytematically to criminal law theory. As such, this innovative, new book will be of great interest to all scholars in this field.
ALASKA SHIPWRECKS 1750-2015 is an encyclopedic accounting of all shipwrecks and losses of life in the Alaska Marine environment. Compiled and written by Captain Warren Good with research assistance and extensive consultation provided by maritime historian Michael Burwell this book is filled with a wealth of information for those interested in Alaska maritime history and the multitude of associated tragedies. Included are details of all known wrecks including vessel information, crew member and passenger names, locations, first hand descriptions of events and sources of all information. In addition, comprehensive comments by Captain Warren Good further elaborate on the location and disposition of many of the disasters.
This illustrated, well indexed book, was created exclusively to help you find your family in Counties Cavan and Leitrim in Ireland. Focusing specifically on families within these neighbouring counties, the book includes an introduction to research and sources in each county. The most numerous families from birth records are given, as well as rather rare Cavan and Leitrim families found in heraldic records. Included you will find a full page map of both counties from the Atlas of Ireland, along with a listing of modern parishes and old townlands, along with the address and location of records for more research. This work includes copies of actual records (some worn, torn and faded), it also includes rough sketches of family coats of arms and notes from centuries past - seldom found elsewhere. The resources provided here will help research any family in the county, including old Irish families, and settler families from England, Scotland, Wales and the continent. This book is a hands on guide for finding your family in Cavan and Leitrim - some family history is included - but it is not a gigantic collection of family histories. For that see 'The Book of Irish Families Great and Small'.
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