Focusing on all current applications, this book presents the various methods as well as their suitability and limitations for a specific question. One particular highlight is the presentation of all basic information on the structure of the relevant objects, thus allowing readers to choose the most suitable applications for any specific problem. They will also find in-depth background information on structure-function relationships, plus descriptions of sample preparations with respect to a particular technique and the necessary equipment. The whole is rounded off with an overview of the future application potential for devices and applications of upcoming interest in biotechnology.
With one new volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of botany. The present volume includes reviews on structural botany, plant physiology, genetics, taxonomy, and geobotany.
Pathogenic Escherichia coli strains use two separate but closely related systems to export important virulence factors. The type 2 secretion (T2S) and type IV pilus (T4P) systems have considerable structural homology; both contain an outer membrane secretin complex, a pilus structure, and an inner membrane subassembly complex. The pilus structure, which predominantly consists of a major pilin subunit, is assembled from individual monomers, although this process remains poorly understood. However, the exported products are different. The T2S secretes fully folded exoproteins like heat-labile toxin through the outer membrane. In this case a pseudopilus structure is proposed to act as a piston to push the substrate through the outer membrane pore. In contrast, the T4P substrate is the pilus itself, and is used by the bacterium for aggregation and attachment to host cells.
Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Dramatically Accelerate the Biomolecular Simulation Process Without Losing Accuracy Real-Time Biomolecular Simulations provides you with proven strategies for shortening the time between product research, breakthrough, and introduction into the market. Based on the author's own innovative research, this rigorous, groundbreaking guide demonstrates how the simulation process can be accelerated yet still provide accurate, dependable results. Everything needed to perform accurate biomolecular simulations in real-time: Algorithms, novel cluster, and grid computing paradigms that enable accurate real-time simulation of biological systems Computational methods for calculating energies and forces Various techniques for sampling, calculating, and performing simulations INSIDE Real-Time Biomolecular Simulations: Introduction to the Dynamics of Biomolecular Systems Classical and Statistical Mechanics of Biomolecular Systems Multiple Time Scale Analysis Protein Dynamics DNA and RNA Dynamics Towards Whole Cell Dynamics
The most comprehensive and up-to-date optics resource available Prepared under the auspices of the Optical Society of America, the five carefully architected and cross-referenced volumes of the Handbook of Optics, Third Edition, contain everything a student, scientist, or engineer requires to actively work in the field. From the design of complex optical systems to world-class research and development methods, this definitive publication provides unparalleled access to the fundamentals of the discipline and its greatest minds. Individual chapters are written by the world's most renowned experts who explain, illustrate, and solve the entire field of optics. Each volume contains a complete chapter listing for the entire Handbook, extensive chapter glossaries, and a wealth of references. This pioneering work offers unprecedented coverage of optics data, techniques, and applications. Volume IV covers optical properties of materials, nonlinear optics, and quantum optics.
Electron Microscopy in Microbiology is a practical guide for microbiologists with little or no previous experience of electron microscopical preparation techniques. Concise descriptions of protocols relevant to microbial research are provided, including procedures for the structural characterization of whole microorganisms and their subcellular and macromolecular components. The handbook covers a wide range of topics from traditional techniques to more recent developments, for example rapid-freezing methods and in situ localization. Advanced undergraduates, postgraduates, researchers, and technicians working with microbes and wishing to understand or simply update their knowledge of electron microscopical techniques will find Electron Microscopy in Microbiology an essential guide.
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