Michael H. Sheldon's Books

Biobanking in the Era of the Stem Cell

A Technical and Operational Guide

By: Jennifer C. Moore,Ronald Philip Hart,Michael H. Sheldon

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Biobanking in the Era of the Stem Cell

A Technical and Operational Guide

By: Jennifer C. Moore,Ronald Philip Hart,Michael H. Sheldon

The study of mental health disorders and the genetics behind these disorders can be greatly enhanced by the use of induced pluripotent stem cells (iPSC). Since many mental health disorders develop after puberty, the only way in which to study the genetic mechanism of these diseases previously was through cellular surrogates, such as blood or cultured fibroblasts. Having the ability to reprogram adult cells to the pluripotent stage provides the capacity to study the onset of these disorders during a culture model of neural development and to include the impact of genetic risk factors and potential environmental triggers. Working with the National Institute of Mental Health (NIMH), the Rutgers Cell and DNA Repository (RUCDR) has begun banking iPSC source cells and converting those source cells into iPSC for distribution to the scientific community. Although initial protocols were developed to reprogram fibroblasts, the ability to reprogram blood cells has several advantages including less invasive collection, less post collection manipulation, and the large number of samples in existing collections. Here, we provide detailed protocols for reprogramming either fibroblasts with retroviral vectors or cryopreserved lymphocytes with Sendai viral vectors. Our goal is to support the discovery of effective treatments for mental health disorders. Table of Contents: Acknowledgments / Introduction / Appendix / General Protocols / References / Author Biographies

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Morgan & Claypool Publishers

Published Date

ISBN 10

1615044728

ISBN 13

9781615044726

An American Health Dilemma

A Medical History of African Americans and the Problem of Race: Beginnings to 1900

By: W. Michael Byrd,Linda A. Clayton

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An American Health Dilemma

A Medical History of African Americans and the Problem of Race: Beginnings to 1900

By: W. Michael Byrd,Linda A. Clayton

At times mirroring and at times shockingly disparate to the rise of traditional white American medicine, the history of African-American health care is a story of traditional healers; root doctors; granny midwives; underappreciated and overworked African-American physicians; scrupulous and unscrupulous white doctors and scientists; governmental support and neglect; epidemics; and poverty. Virtually every part of this story revolves around race. More than 50 years after the publication of An American Dilemma, Gunnar Myrdal's 1944 classic about race relations in the USA, An American Health Dilemma presents a comprehensive and groundbreaking history and social analysis of race, race relations and the African-American medical and public health experience. Beginning with the origins of western medicine and science in Egypt, Greece and Rome the authors explore the relationship between race, medicine, and health care from the precursors of American science and medicine through the days of the slave trade with the harrowing middle passage and equally deadly breaking-in period through the Civil War and the gains of reconstruction and the reversals caused by Jim Crow laws. It offers an extensive examination of the history of intellectual and scientific racism that evolved to give sanction to the mistreatment, medical abuse, and neglect of African Americans and other non-white people. Also included are biographical portraits of black medical pioneers like James McCune Smith, the first African American to earn a degree from a European university, and anecdotal vignettes,like the tragic story of "the Hottentot Venus", which illustrate larger themes. An American Health Dilemma promises to become an irreplaceable and essential look at African-American and medical history and will provide an invaluable baseline for future exploration of race and racism in the American health system.

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708

Publisher

Routledge

Published Date

ISBN 10

1135960488

ISBN 13

9781135960483

The Fourth Amendment in Flux

The Roberts Court, Crime Control, and Digital Privacy

By: Michael C. Gizzi,R. Craig Curtis

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The Fourth Amendment in Flux

The Roberts Court, Crime Control, and Digital Privacy

By: Michael C. Gizzi,R. Craig Curtis

When the Founders penned the Fourth Amendment to the Constitution, it was not difficult to identify the “persons, houses, papers, and effects” they meant to protect; nor was it hard to understand what “unreasonable searches and seizures” were. The Fourth Amendment was intended to stop the use of general warrants and writs of assistance and applied primarily to protect the home. Flash forward to a time of digital devices, automobiles, the war on drugs, and a Supreme Court dominated by several decades of the jurisprudence of crime control, and the legal meaning of everything from “effects” to “seizures” has dramatically changed. Michael C. Gizzi and R. Craig Curtis make sense of these changes in The Fourth Amendment in Flux. The book traces the development and application of search and seizure law and jurisprudence over time, with particular emphasis on decisions of the Roberts Court. Cell phones, GPS tracking devices, drones, wiretaps, the Patriot Act, constantly changing technology, and a political culture that emphasizes crime control create new challenges for Fourth Amendment interpretation and jurisprudence. This work exposes the tensions caused by attempts to apply pretechnological legal doctrine to modern problems of digital privacy. In their analysis of the Roberts Court’s relevant decisions, Gizzi and Curtis document the different approaches to the law that have been applied by the justices since the Obama nominees took their seats on the court. Their account, combining law, political science, and history, provides insight into the court’s small group dynamics, and traces changes regarding search and seizure law in the opinions of one of its longest serving members, Justice Antonin Scalia. At a time when issues of privacy are increasingly complicated by technological advances, this overview and analysis of Fourth Amendment law is especially welcome—an invaluable resource as we address the enduring question of how to balance freedom against security in the context of the challenges of the twenty-first century.

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200

Publisher

University Press of Kansas

Published Date

ISBN 10

0700622578

ISBN 13

9780700622573

And Then They Loved Him

Seward Collins & the Chimera of an American Fascism

By: Michael Jay Tucker

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And Then They Loved Him

Seward Collins & the Chimera of an American Fascism

By: Michael Jay Tucker

In Jazz Age America and Europe few stars burned brighter than Seward Collins, who seemingly had it all - money, breeding, good looks, and literary talent. His friends included Fitzgerald, Dreiser, Mencken, and Hemingway, while among his lovers was Dorothy Parker. Yet, in the 1930s, this glittering creature would announce that he was a «Fascist». This book, useful for any study of the American Jazz Age or world Fascism, explores Collins' curious story, and asks if there might be a Fascist tradition in America, as much a part of the nation as Flag Day and apple pie.

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222

Publisher

Peter Lang

Published Date

ISBN 10

0820479101

ISBN 13

9780820479101

The Criminal Brain, Second Edition

Understanding Biological Theories of Crime

By: Nicole Rafter,Chad Posick,Michael Rocque

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The Criminal Brain, Second Edition

Understanding Biological Theories of Crime

By: Nicole Rafter,Chad Posick,Michael Rocque

A lively, up-to-date overview of the newest research in biosocial criminology What is the relationship between criminality and biology? Nineteenth-century phrenologists insisted that criminality was innate, inherent in the offender’s brain matter. While they were eventually repudiated as pseudo-scientists, today the pendulum has swung back. Both criminologists and biologists have begun to speak of a tantalizing but disturbing possibility: that criminality may be inherited as a set of genetic deficits that place one at risk to commit theft, violence, or acts of sexual deviance. But what do these new theories really assert? Are they as dangerous as their forerunners, which the Nazis and other eugenicists used to sterilize, incarcerate, and even execute thousands of supposed “born” criminals? How can we prepare for a future in which leaders may propose crime-control programs based on biology? In this second edition of The Criminal Brain, Nicole Rafter, Chad Posick, and Michael Rocque describe early biological theories of crime and provide a lively, up-to-date overview of the newest research in biosocial criminology. New chapters introduce the theories of the latter part of the 20th century; apply and critically assess current biosocial and evolutionary theories, the developments in neuro-imaging, and recent progressions in fields such as epigenetics; and finally, provide a vision for the future of criminology and crime policy from a biosocial perspective. The book is a careful, critical examination of each research approach and conclusion. Both compiling and analyzing the body of scholarship devoted to understanding the criminal brain, this volume serves as a condensed, accessible, and contemporary exploration of biological theories of crime and their everyday relevance.

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395

Publisher

NYU Press

Published Date

ISBN 10

1479894699

ISBN 13

9781479894697

Scientific Babel

How Science Was Done Before and After Global English

By: Michael D. Gordin

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Scientific Babel

How Science Was Done Before and After Global English

By: Michael D. Gordin

English is the language of science today. No matter which languages you know, if you want your work seen, studied, and cited, you need to publish in English. But that hasn’t always been the case. Though there was a time when Latin dominated the field, for centuries science has been a polyglot enterprise, conducted in a number of languages whose importance waxed and waned over time—until the rise of English in the twentieth century. So how did we get from there to here? How did French, German, Latin, Russian, and even Esperanto give way to English? And what can we reconstruct of the experience of doing science in the polyglot past? With Scientific Babel, Michael D. Gordin resurrects that lost world, in part through an ingenious mechanism: the pages of his highly readable narrative account teem with footnotes—not offering background information, but presenting quoted material in its original language. The result is stunning: as we read about the rise and fall of languages, driven by politics, war, economics, and institutions, we actually see it happen in the ever-changing web of multilingual examples. The history of science, and of English as its dominant language, comes to life, and brings with it a new understanding not only of the frictions generated by a scientific community that spoke in many often mutually unintelligible voices, but also of the possibilities of the polyglot, and the losses that the dominance of English entails. Few historians of science write as well as Gordin, and Scientific Babel reveals his incredible command of the literature, language, and intellectual essence of science past and present. No reader who takes this linguistic journey with him will be disappointed.

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424

Publisher

University of Chicago Press

Published Date

ISBN 10

022600029X

ISBN 13

9780226000299

Scrawny to Brawny

The Complete Guide to Building Muscle the Natural Way

By: Michael Mejia,John Berardi

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Scrawny to Brawny

The Complete Guide to Building Muscle the Natural Way

By: Michael Mejia,John Berardi

A resource for "skinny" men looking to add mass and muscle offers a progressive workout program that emphasizes optimized workouts and an action-based perspective on nutrition, as well as vital information on understanding and preventing injury. Original. 30,000 first printing.

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259

Publisher

Rodale

Published Date

ISBN 10

1594860882

ISBN 13

9781594860881

In the Shadow Of the Poorhouse

A Social History Of Welfare In America, Tenth Anniversary Edition

By: Michael B. Katz

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In the Shadow Of the Poorhouse

A Social History Of Welfare In America, Tenth Anniversary Edition

By: Michael B. Katz

With welfare reform a burning political issue, this special anniversary edition of the classic history of welfare in America has been revised and updated to include the latest bipartisan debates on how to "end welfare as we know it". With an informative new Introduction and a new concluding chapter, this timely edition makes for important reading. Index.

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412

Publisher

Perseus (for Hbg)

Published Date

ISBN 10

0465032109

ISBN 13

9780465032105

Risk Assessment

Logic and Measurement

By: Michael C. Newman,Carl Strojan

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Risk Assessment

Logic and Measurement

By: Michael C. Newman,Carl Strojan

Accurate risk assessments are vital to the protection of human, environmental, and ecosystem health. Risk Assessment provides a current, comprehensive reference for researchers and professionals concerned with environmental contamination as well as its effects on humans and ecosystems.

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372

Publisher

CRC Press

Published Date

ISBN 10

1575040484

ISBN 13

9781575040486

12-Day Body Shaping Miracle

Change Your Shape, Transform Problem Areas, and Beat Fat for Good

By: Michael Thurmond

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12-Day Body Shaping Miracle

Change Your Shape, Transform Problem Areas, and Beat Fat for Good

By: Michael Thurmond

Wonder why all those hours spent on the treadmill or lifting weights aren't getting you the results you want? According to Thurmond, if you're not working out in a way that's just right for your individual body type, you're wasting time and energy. In 12-DAY BODY SHAPING MIRACLE, Michael Thurmond presents his breakthrough exercise program for getting your body into a better proportional balance. Using Thurmond's exclusive "blueprinting system", you'll identify your unique metabolism and body type. You'll then discover a personalized exercise plan to quickly target your specific problem areas and transform your body shape in just 12 days. For example, if you are bottom heavy, you learn how to trim your thighs and hips while building up your shoulders and back, giving your body that trimmer, more hourglass-like shape. Thurmond's unique program focuses on sculpting muscles through select, easy-to-do weight training techniques with cardiovascular activity. And, no matter what your starting weight, level of fitness or shape is, Thurmond guarantees rapid results.

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Page Count

180

Publisher

Grand Central Life & Style

Published Date

ISBN 10

044655426X

ISBN 13

9780446554268

The Complete Cancer Cleanse

A Proven Program to Detoxify and Renew Body, Mind, and Spirit

By: Cherie Calbom,John Calbom,Michael Mahaffey

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The Complete Cancer Cleanse

A Proven Program to Detoxify and Renew Body, Mind, and Spirit

By: Cherie Calbom,John Calbom,Michael Mahaffey

Cherie Calbom, "The Juice Lady," therapist John Calbom, and Michael Mahaffey, a twenty-year cancer survivor, present a unique, multi-disciplinary approach to fighting cancer.

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226

Publisher

HarperChristian + ORM

Published Date

ISBN 10

1418514772

ISBN 13

9781418514778

Jonathan Edwards and Justification by Faith

By: Michael McClenahan

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Jonathan Edwards and Justification by Faith

By: Michael McClenahan

Jonathan Edwards (1703-1758) is widely regarded as North America's most influential theologian. Throughout the early decades of his ministry he engaged in a public and sustained debate with 'Arminian' theology, a crusade that contributed significantly to the events of the Great Awakening. This book investigates the contours and substance of this theological war. In establishing a clearer historical context for this polemic, McClenahan seeks to overturn the scholarly consensus that Edwards' own theology was a twisting of the Reformed tradition. By demonstrating that Edwards' interlocutor was the dead English Archbishop, John Tillotson, McClenahan provides the hermeneutical key for many of Edwards' most significant works. Justification by faith is one of the most contested doctrines in contemporary theology and Jonathan Edwards, referred to as America's Augustine, wrote extensively on this area. His is a voice that many people are keen to hear.

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238

Publisher

Routledge

Published Date

ISBN 10

1317110374

ISBN 13

9781317110378

Sniper

Inside the Hunt for the Killers Who Terrorized the Nation

By: Sari Horwitz,Michael Ruane

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Sniper

Inside the Hunt for the Killers Who Terrorized the Nation

By: Sari Horwitz,Michael Ruane

Sniper is the behind-the-scenes story of one of the most frightening rampages to occur in U.S. history—and how it was stopped. For more than three weeks, the nation watched in disbelief as Washington, D.C., and its surrounding suburbs were held hostage by anonymous gunmen shooting innocent civilians at random. Sniper is the deﬁnitive account of those alleged gunmen, John Muhammad and Lee Boyd Malvo, and the massive manhunt that ended with their capture by a heavily armed SWAT team in an early-morning raid at an interstate highway rest stop. Two Washington Post reporters, Sari Horwitz and Michael E. Ruane, retrace the steps of Muhammad and Malvo from their ﬁrst meeting on the island of Antigua to Malvo’s deﬁant confession in a Virginia jail. Drawing on exclusive reporting about that confession, internal police documents, and a wide range of law-enforcement sources, Horwitz and Ruane track in remarkable detail the murderous trail Muhammad and Malvo are accused of having followed to the Washington area and reconstruct the eerie way in which the two moved invisibly around the nation’s capital in the midst of one of the largest police investigations in U.S. history. Horwitz and Ruane also take you inside the police command center where local and state police, joined by the federal government’s most experienced crime ﬁghters, worked desperately to stop the killings, unaware that a fundamental error—investigators were wrongly ﬁxated on a white van—was allowing Muhammad and Malvo to slip through the dragnet. We meet FBI negotiators, veteran detectives, forensics experts, prosecutors, and politicians who faced perhaps the biggest challenge of their careers as they confronted frustrating setbacks, logistical nightmares, and the overwhelming pressure of a high-stakes investigation. In a fast-paced narrative that outdoes even the most acclaimed television cop shows, Sniper recounts the extraordinary police work that enabled investigators to quickly exploit the clues handed to them by Muhammad and Malvo that ﬁnally led to their arrest. Part gripping drama, part real-life portrait of law enforcement at work, Sniper is also a cautionary tale about the vulnerability of American society in an age of terrorism.

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Page Count

338

Publisher

Ballantine Books

Published Date

ISBN 10

034547662X

ISBN 13

9780345476623

Book's by Michael H. Sheldon

Biobanking in the Era of the Stem Cell

Biobanking in the Era of the Stem Cell

An American Health Dilemma

An American Health Dilemma

The Fourth Amendment in Flux

The Fourth Amendment in Flux

And Then They Loved Him

And Then They Loved Him

The Criminal Brain, Second Edition

The Criminal Brain, Second Edition

Scientific Babel

Scientific Babel

Scrawny to Brawny

Scrawny to Brawny

In the Shadow Of the Poorhouse

In the Shadow Of the Poorhouse

Risk Assessment

Risk Assessment

12-Day Body Shaping Miracle

12-Day Body Shaping Miracle

The Complete Cancer Cleanse

The Complete Cancer Cleanse

Jonathan Edwards and Justification by Faith

Jonathan Edwards and Justification by Faith

Sniper

Sniper

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