Commercial gambling is a recent historical phenomenon. It has developed into a profitable industry that supplies a range of recreational activities to its customers, and is a significant way of collecting money from players to distribute to companies, state budgets, and other beneficiaries. Many of these are civil society organizations, using the money for producing services in sports, culture, social work, and health care. However, gambling can also develop into pathological behaviour. Using a public interest framework, this book discusses the policies that will best serve the public good and minimize individual and collective harms. After describing the historical context of the gambling and the current global burden of the activity, available methods of regulating the industry are evaluated using the available scientific evidence. By analysing the effectiveness of gambling policies and their alignment with the public interest, the epidemiological obstacles to successful regulation are considered in detail. There is good evidence for the effectiveness of restrictions on availability and access, but preventing gambling-related harm is not possible without limiting the overall volume of the activity, and hence the profits for the gambling industry and governments. Taking an international approach, this book delivers a comprehensive review of the epidemiological evidence documenting the harmful effects of gambling on individuals, communities, and societies. Essential reading for policymakers, social and behavioural scientists in gambling research, and public health researchers, Setting Limits examines a global view of an emerging epidemic of gambling problems.
Cats are masters of the art of survival, independent and elegant. Although loved by humans, they often end up in need. Near the Austro-Bavarian border there is a sanctuary for cats called Gut Aiderbichl. Here homeless and needy cats regain their self-confidence. In this "villa" of their dreams, they have their own parlor, a cozy kitchen, and even a large bedroom! There's lots of room to play a or to get away from it all. Get to know these feline's fascinating stories and enjoy heartwarming photographs of their newfound contentment. These stories bear witness to their courage and endurance, and their desire to be petted!
First Prize, Orthopaedics and Rheumatology, BMA Awards 2009 This state-of-the-art reference provides current insights into the etiology, diagnosis and management of rheumatoid arthritis. Leading international authorities in RA examine all of the latest scientific and clinical developments in understanding and managing this challenging disease, including new concepts in pathogenesis, epidemiology, risk factors, imaging, clinical outcomes and treatment. It’s the guidance you need to offer optimal care to your patients with rheumatoid arthritis. Presents the work of leading international experts in rheumatoid arthritis for guidance you can trust. Provides the very latest understanding of the pathogenesis of rheumatoid arthritis, including molecular pathways/mechanisms, and genetic and environmental factors that instigate and drive the disease. Includes comprehensive coverage of clinical features of rheumatoid arthritis including articular, peri-articular and extra-articular manifestations, comorbidities, and outcome measures—disease activity, joint assessment, imaging, and more—for expert diagnosis and monitoring of disease progression. Examines evidence-based treatment options—including traditional and biologic DMARDs and combination therapies—as well as promising therapies on the horizon, placing up-to-date guidance on disease modifying or disease controlling agents at your fingertips.
Consistently lauded for its comprehensiveness and full-color color presentation, the latest edition of Rheumatology by Marc C. Hochberg, MD, MPH et al. continues the tradition of excellence of previous editions. Designed to meet the needs of the practicing clinician, it provides extensive, authoritative coverage of rheumatic disease from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format covering all major disorders of the musculoskeletal system in complete, self-contained chapters. Get trusted perspectives and insights from chapters co-authored by internationally renowned leaders in the field, 25% of whom are new to this edition. Track disease progression and treat patients more effectively with the most current information, including 22 new chapters on genetic findings, imaging outcomes, and cell and biologic therapies as well as rheumatoid arthritis and SLE. Incorporate the latest findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics.
In this book, Michael Smith offers a comparative and interdisciplinary examination of ancient settlements and cities. Early cities varied considerably in their political and economic organization and dynamics. Smith here introduces a coherent approach to urbanism that is transdisciplinary in scope, scientific in epistemology, and anchored in the urban literature of the social sciences. His new insight is 'energized crowding,' a concept that captures the consequences of social interactions within the built environment resulting from increases in population size and density within settlements. Smith explores the implications of features such as empires, states, markets, households, and neighborhoods for urban life and society through case studies from around the world. Direct influences on urban life – as mediated by energized crowding-are organized into institutional (top-down forces) and generative (bottom-up processes). Smith's volume analyzes their similarities and differences with contemporary cities, and highlights the relevance of ancient cities for understanding urbanism and its challenges today.
Tap into the gold standard on central nervous system infections: Infections of the Central Nervous System, 4e is now fully revised and updated to accommodate the wealth of new CNS information discovered over the past decade. More than 90 leading experts contribute chapters, providing comprehensive, up-to-date information. With a broad scope and thorough detail, the text addresses pathogenesis, clinical manifestations, diagnosis, and therapy of various CNS infections and related conditions. Features: Every chapter has been extensively revised and updated, nearly half with new author teams NEW chapter on acute encephalitis NEW clinical information on treatment of tuberculosis, non-tubercular mycobacterial infections, brain abscess, and Lyme disease NEW color design and color images Numerous diagrams, figures, tables, illustrations and photographs demonstrate the content Evidence-based references
50th Anniversary Edition of the groundbreaking case-based pharmacotherapy text, now a convenient two-volume set. Celebrating 50 years of excellence, Applied Therapeutics, 12th Edition, features contributions from more than 200 experienced clinicians. This acclaimed case-based approach promotes mastery and application of the fundamentals of drug therapeutics, guiding users from General Principles to specific disease coverage with accompanying problem-solving techniques that help users devise effective evidence-based drug treatment plans. Now in full color, the 12th Edition has been thoroughly updated throughout to reflect the ever-changing spectrum of drug knowledge and therapeutic approaches. New chapters ensure contemporary relevance and up-to-date IPE case studies train users to think like clinicians and confidently prepare for practice.
A novel in three parts, linked by a single narrative of disaster, loss, and longing. TOKYO is an incisive, shape-shifting tour de force, a genre-bending mix of lyric prose, science fiction, horror, and visual collage exploring the erotic undercurrents of American perceptions of Japanese culture and identity. By turns noir, surreal, and clinical in its language and style, TOKYO employs metaphors of consumption, disease, theater, gender fluidity, monstrousness, and ecological disaster in intertwined accounts touching on matters of cultural appropriation, fiction's powerful capacity to produce immersive realities, and the culturally corrupting late capitalist excesses that entangle both the United States and Japan. The novel opens with a fantastic, slyly comic report written by a Japanese executive, describing the anomalous bluefin tuna his company purchased at Tokyo’s iconic fish market, as well as the dissolution of the executive’s marriage to his Japanese-American, or Sansei, wife. But when an American writer—whose own Sansei wife was previously married to a Japanese executive—begins investigating the report’s author and his claims, assisted by a mysterious Japanese correspondent the American suspects may once have been his wife’s lover, identities begin to scramble until it’s uncertain who is imagining who, and who is and isn’t Japanese. Meanwhile, a secret plot to establish pure Japaneseness through the global distribution of genetically engineered bluefin tuna seems to be rushing toward its conclusion like a great wave.
This brand new Annual Plant Reviews volume is the second edition of the highly successful and well-received Annual Plant Reviews, Volume 2. This exciting new volume provides an up-to-date survey of the biochemistry and physiology of plant secondary metabolism. The volume commences with an overview of the biochemistry, physiology and function of secondary metabolism, followed by detailed reviews of the major groups of secondary metabolites: alkaloids and betalains, cyanogenic glucosides, glucosinolates and nonprotein amino acids, phenyl propanoids and related phenolics, terpenoids, cardiac glycosides and saponins. A final chapter discusses the evolution of secondary metabolism. This carefully compiled new edition brings together chapters from some of the world's leading experts in plant secondary metabolism. Completely revised and brought right up to date with much new information, this volume is an essential purchase for advanced students, researchers and professionals in biochemistry, physiology, molecular biology, genetics, plant sciences, agriculture, medicine, pharmacology and pharmacy, working in the academic and industrial sectors, including those working in the pesticide and pharmaceutical industries. Libraries in all universities and research establishments where these subjects are studied and taught will need copies of this excellent volume on their shelves. A companion volume Annual Plant Reviews Volume 39, Functions and Biotechnology of Plant Secondary Metabolites, Second Edition, Edited by M. Wink, is also available.
Zakim and Boyer's Hepatology-the defining work in hepatology-presents comprehensive coverage of both basic science and clinically relevant developments so you can provide the best possible patient care. Drs. Thomas Boyer, Michael Manns, and Arun Sanyal have reorganized and updated the contents of this trusted global reference to reflect today's more clinical approach to hepatology. They bring you up to date on hot topics including HIV Co-Infection Drug Toxicity, Hepatocellular Carcinoma (HCC), and much more. This new streamlined edition is now a single volume with access to the fully searchable contents and an image bank online at www.expertconsult.com making it easier to find the treatment information you need. Effectively treat all liver diseases currently seen in clinical practice with authoritative guidance from leading international authorities. Reinforce your foundation in basic science with the concise Pathophysiology of Therapeutic Targets section. See clear presentations of liver disease through hundreds of detailed, color illustrations. Explore topics further with up-to-date references that direct you to the significant literature. Access the complete, fully searchable contents of the book online at www.expertconsult.com, along with a downloadable image bank and complete list of references. Stay current on new developments in the field through five new chapters on Pathogenesis Liver Injury in HBV, HCV; HCC; Imaging and Non-Invasive DX Liver Disease CT, US, Fibroscan, MRI; HIV Co-Infection Drug Toxicity; and HBC, HCV in Non-Liver Transplant Patients, plus comprehensive updates throughout. Apply best practices with reorganized and updated content that reflects today's need for a more clinical approach to hepatology. Reference key information more easily thanks to streamlined content that now fits into one volume.
Malignant Lymphomas ACS American Cancer Society Atlas of Clinical Oncology Malignant Lymphomas is a volume in the acclaimed American Cancer Society Atlas of Clinical Oncology series. Dr. Grossbard and his team have summarized current knowledge on the pathology, epidemiology, molecular biology, presentation and management of ......
Ideal for fellows and practicing pulmonologists who need an authoritative, comprehensive reference on all aspects of pulmonary medicine, Murray and Nadel’s Textbook of Respiratory Medicine offers the most definitive content on basic science, diagnosis, evaluation and treatment of the full spectrum of respiratory diseases. Full-color design enhances teaching points and highlights challenging concepts. Understand clinical applications and the scientific principles of respiratory medicine. Detailed explanations of each disease entity allow you to work through differential diagnoses. Expert Consult eBook version included with purchase. This enhanced eBook experience offers content updates, videos, review questions, and Thoracic Imaging Cases (TICs), all of which are easily navigable on any device for access on rounds or in the clinic. Includes more than 1,000 figures and over 200 videos and audio files. Key Points and Key Reading sections highlight the most useful references and resources for each chapter. An expanded sleep section now covers four chapters and includes control of breathing, consequences of sleep disruption, as well as obstructive and central apnea. New chapters in the Critical Care section cover Noninvasive Ventilation (NIV) and Extracorporeal Support of Gas Exchange (ECMO). New chapters focusing on diagnostic techniques now include Invasive Diagnostic Imaging and Image-Guided Interventions and Positron Emission Tomography, and a new chapter on Therapeutic Bronchoscopy highlights the interventional role of pulmonologists. Embedded videos feature thoracoscopy, therapeutic bronchoscopy, volumetric chest CT scans, and more. Brand-new audio files highlight normal and abnormal breath sounds and the separate components of cough.
Commercial gambling is a recent historical phenomenon. It has developed into a profitable industry that supplies a range of recreational activities to its customers, and is a significant way of collecting money from players to distribute to companies, state budgets, and other beneficiaries. Many of these are civil society organizations, using the money for producing services in sports, culture, social work, and health care. However, gambling can also develop into pathological behaviour. Using a public interest framework, this book discusses the policies that will best serve the public good and minimize individual and collective harms. After describing the historical context of the gambling and the current global burden of the activity, available methods of regulating the industry are evaluated using the available scientific evidence. By analysing the effectiveness of gambling policies and their alignment with the public interest, the epidemiological obstacles to successful regulation are considered in detail. There is good evidence for the effectiveness of restrictions on availability and access, but preventing gambling-related harm is not possible without limiting the overall volume of the activity, and hence the profits for the gambling industry and governments. Taking an international approach, this book delivers a comprehensive review of the epidemiological evidence documenting the harmful effects of gambling on individuals, communities, and societies. Essential reading for policymakers, social and behavioural scientists in gambling research, and public health researchers, Setting Limits examines a global view of an emerging epidemic of gambling problems.
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