50th Anniversary Edition of the groundbreaking case-based pharmacotherapy text, now a convenient two-volume set. Celebrating 50 years of excellence, Applied Therapeutics, 12th Edition, features contributions from more than 200 experienced clinicians. This acclaimed case-based approach promotes mastery and application of the fundamentals of drug therapeutics, guiding users from General Principles to specific disease coverage with accompanying problem-solving techniques that help users devise effective evidence-based drug treatment plans. Now in full color, the 12th Edition has been thoroughly updated throughout to reflect the ever-changing spectrum of drug knowledge and therapeutic approaches. New chapters ensure contemporary relevance and up-to-date IPE case studies train users to think like clinicians and confidently prepare for practice.
Emergency physicians assess and manage a wide variety of problems from patients presenting with a diversity of severities, ranging from mild to severe and life-threatening. They are expected to maintain their competency and expertise in areas where there is rapid knowledge change. Evidence-based Emergency Medicine is the first book of its kind in emergency medicine to tackle the problems practicing physicians encounter in the emergency setting using an evidence-based approach. It summarizes the published evidence available for the diagnosis and treatment of common emergency health care problems in adults. Each chapter contextualizes a topic area using a clinical vignette and generates a series of key clinically important diagnostic and treatment questions. By completing detailed reviews of diagnostic and treatment research, using evidence from systematic reviews, RCTs, and prospective observational studies, the authors provide conclusions and practical recommendations. Focusing primarily on diagnosis in areas where evidence for treatment is well accepted (e.g. DVTs), and treatment in other diseases where diagnosis is not complex (e.g. asthma), this text is written by leading emergency physicians at the forefront of evidence-based medicine. Evidence-based Emergency Medicine is ideal for emergency physicians and trainees, emergency department staff, and family physicians specialising in the acute care of medical and injured patients.
Drs. John C. Perkins and Michael E. Winters have assembled an expert team of authors on the topic of Sepsis in the Emergency Department. Article topics include: Defining and Diagnosing Sepsis; Appropriate Antibiotic Therapy; Severe Sepsis Resuscitation in Resource Limited Settings; Source Control in Severe Sepsis; Considerations in Special Populations with Severe Sepsis; Pediatric Severe Sepsis Resuscitation; The New Usual Care; Prehospital Sepsis Care; Endpoints of Sepsis Resuscitation; Pitfalls in the Diagnosis, Treatment, and Disposition of Severe Sepsis; Biomarkers in Sepsis; Vasopressors and Inotropes in Sepsis; and Sepsis Quality Measures and Performance Improvement.
St Francis of Assisi is one of the most admired figures of the Middle Ages - and one of the most important in the Christian church, modelling his life on the literal observance of the Gospel and recovering an emphasis on the poverty experienced by Jesus Christ. From 1217 Francis sent communities of friars throughout Christendom and launched missions to several countries, including India and China. The movement soon became established in most cities and several large towns, and, enjoying close relations with the popes, its followers were ideal instruments for the propagation of the reforms of the Fourth Lateran Council of 1215. They quickly became part of the landscape of medieval life and made their influence felt throughout society.BR>This book explores the first 250 years of the order's history and charts its rapid growth, development, pastoral ministry, educational organisation, missionary endeavour, internal tensions and divisions. Intended for both the general and more specialist reader, it offers a complete survey of the Franciscan Order. Dr MICHAEL ROBSON is a Fellow and Director of Studies in Theology at St Edmund's College, Cambridge
Applications of Fire Research and Improvement, Second Edition, provides the basic principles of research and research-based improvement methodologies for analyzing fire-related processes research.
At the time of the Dreyfus Affair and the start of the Action Française, Charles Maurras pressed forward the idea, borrowed from Auguste Comte, of an alliance between Positivists and Catholics. This study of Maurrassian ideology and Catholic reactions to it explores a wide range of themes.
Beginning in the late twelfth century, scholastic theologians such as William of Auvergne, Thomas Aquinas and Engelbert of Admont attempted to provide a rational foundation to the Christian belief in miracles, bolstered by the Aristotelian theory of natural law. Similarly in this period a tension appeared to exist in the recording of miracles, between the desire to exalt the Faith and the need to guarantee believability in the face of opposition from heretics, Jews and other sceptics. As miracles became an increasingly standard part of evidence leading to canonization, the canon lawyers, notaries and theologians charged with determining the authenticity of miracles were eventually issued with a list of questions to which witnesses to the event were asked to respond, a virtual template against which any miracle could be measured. Michael Goodich explores this changing perception of the miracle in medieval Western society. He employs a wealth of primary sources, including canonization dossiers and contemporary hagiographical Vitae and miracle collections, philosophical/theological treatises, sermons, and canon law and ancillary sources dealing with the procedure of canonization. He compares and contrasts 'popular' and learned understanding of the miraculous and explores the relationship between reason and revelation in the medieval understanding of miracles. The desire to provide a more rational foundation to the Christian belief in miracles is linked to the rise of heresy and other forms of disbelief, and finally the application of the rules of evidence in the examination of miracles in the central Middle Ages is scrutinized. This absorbing book will appeal to scholars working in the fields of medieval history, religious and ecclesiastical history, canon law, and all those with an interest in hagiography.
In World History as the History of Foundations, 3000 BCE to 1500 CE, Michael Borgolte investigates the origins and development of foundations from Antiquity to the end of the Middle Ages. In his survey foundations emerge not as mere legal institutions, but rather as “total social phenomena” which touch upon manifold aspects, including politics, the economy, art and religion of the cultures in which they emerged. Cross-cultural in its approach and the result of decades of research, this work represents by far the most comprehensive account of the history of foundations that has hitherto been published.
Dr. Michael Pinsky has assembled an expert team of authors on the topic of Hemodynamic Monitoring. Articles topics include: The interface between monitoring and physiology at the bedside; Defining goals of resuscitation in the critically ill; Minimally invasive hemodynamic monitoring; Bedside ultrasound for the intensivist; Invasive hemodynamic monitoring; Functional hemodynamic monitoring; Using what you get: dynamic physiological signatures of critical illness; and Effect of organizational issues on resuscitation effectiveness.
The Politics of Religion in Napoleonic Italy explores the intense cultural conflict created by French rule in Italy at the start of the nineteenth century. Napoleon's desire for cultural conformity struck at the heart of Italian religious life. Yet the reforms imposed by French rule created resentment and resistance across Italy, finally leading to Napoleon's famous quarrel with Pope Pius VII. In this fascinating study, Mike Broers traces the events leading up to the ex-communication of Napoleon and the Pope's arrest and exile from Rome. Using previously neglected French and Italian archival sources, this book reveals how the alliance between Church and people grew in the face of alien, imperial rule. It exposes the vital role this union played in preventing Italy from being totally assimilated into the French empire.
An indispensable guide to the earliest contemporary account of the Franciscan Order in England.Known as Friars Minor, Franciscans or Greyfriars, the followers of St Francis of Assisi pioneered a new type of religious life, moving beyond the monastic cloister. Their ministry was to bring the Gospel to life through example, preaching, gesture, drama, music and poetry. Founded in 1209, the movement became rapidly popular and spread widely across Europe.By around 1257 there were 49 communities In England, housing some 1,242 friars. The story of the Franciscans' arrival, and the growth of the Order up until c.1257/1258, is related by the chronicler Thomas of Eccleston In his De Adventu Fratrum Minorum in Angliam. The story is not untroubled: for example, Eccleston does not shy away from the painful controversies of the later 1230s, when there were deep divisions about the exercise of authority in the Order. He was disturbed by some developments in the Order and showed his support for caution in the schools and in relation to building, at a time when friars were exposed to searching criticisms. The chronological account is accompanied by exemplum materials which illuminate the friars' preaching and teaching, and by a gallery of virtuous individual friars.This book is the first full-length study of the text, examining it in detail, and providing a careful elucidation.relation to building, at a time when friars were exposed to searching criticisms. The chronological account is accompanied by exemplum materials which illuminate the friars' preaching and teaching, and by a gallery of virtuous individual friars.This book is the first full-length study of the text, examining it in detail, and providing a careful elucidation.relation to building, at a time when friars were exposed to searching criticisms. The chronological account is accompanied by exemplum materials which illuminate the friars' preaching and teaching, and by a gallery of virtuous individual friars.This book is the first full-length study of the text, examining it in detail, and providing a careful elucidation.relation to building, at a time when friars were exposed to searching criticisms. The chronological account is accompanied by exemplum materials which illuminate the friars' preaching and teaching, and by a gallery of virtuous individual friars.This book is the first full-length study of the text, examining it in detail, and providing a careful elucidation.
This is the first English language biography of Ottorino Respighi, the most performed Italian composer of the twentieth century. Best known for his so-called Roman trilogy, (Fountains of Rome, Pines of Rome and Roman Festivals), this book documents the story of his rise to fame and offers a fascinating insight into the active lifestyle of an internationally renowned musician, who made an important contribution to the revival of interest in early music. It also takes a closer look at Respighi’s associations with eminent figures such as Arturo Toscanini, Serge Diaghilev, Gabriele D’Annunzio and even Albert Einstein which make his story deeply engaging and take us beyond the realms of music into a world of Russian émigrés, wealthy patrons and Nobel Prize winners, while also documenting some of the early effects of fascism on art and culture.
Consistently lauded for its comprehensiveness and full-color color presentation, the latest edition of Rheumatology by Marc C. Hochberg, MD, MPH et al. continues the tradition of excellence of previous editions. Designed to meet the needs of the practicing clinician, it provides extensive, authoritative coverage of rheumatic disease from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format covering all major disorders of the musculoskeletal system in complete, self-contained chapters. Get trusted perspectives and insights from chapters co-authored by internationally renowned leaders in the field, 25% of whom are new to this edition. Track disease progression and treat patients more effectively with the most current information, including 22 new chapters on genetic findings, imaging outcomes, and cell and biologic therapies as well as rheumatoid arthritis and SLE. Incorporate the latest findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics.
During the Renaissance there was no centralized Inquisition in northern Italy until Pope Paul III founded the Roman Inquisition in 1542, but there was a dense network of autonomous papal inquisitors. Based on extensive archival research, this study investigates the life of the Dominican friars from whom these inquisitors were mostly drawn. It focuses on a selection of hitherto almost unknown but representative inquisitors to cast new light on their formation, appointment and careers, as well as their principal pursuits - the prosecution of heretics, especially Waldensians and Judaizers, and, most of all, the hunting of witches, for it was at its most intense in northern Italy during the Renaissance, over a century before reaching its peak in Northern Europe.
Using an easy-to-read style, Avoiding Common Errors in the Emergency Department, Third Edition, discusses 365 topics in which errors are frequently committed in the practice of emergency medicine. The authors give practical, easy-to-remember key points for avoiding these pitfalls. Chapters are brief, evidence-based, and easy-to-read immediately before the start of a shift, used for quick reference during a shift, or read daily over the course of one year for personal growth and review. Drs. Michael E. Winters, Dale P. Woolridge, Evie Marcolini, Mimi Lu, and Sarah B. Dubbs have fully revised this edition offering a fresh perspective in this rapidly changing field.
This edition of Bouncebacks! Emergency Medicine books examines the bounceback visit, putting the reader in the footsteps of the clinician as the patient deteriorates. The story pauses at important decision points as possible management strategies are reviewed in a literature-based fashion, followed by a revelation of the path chosen by the actual provider. As the patient’s course progresses, we reach additional decision points and address further clinical questions. In addition to our chapter authors, many with expertise in critical care emergency medicine, we have an all-star lineup of expert-whisperers: first an EM/critical care section editor (below) and second, EMCRIT.org’s double-boarded critical care guru, Scott Weingart. Their comments are inserted in grey boxes and are intended to give tips and tricks borne of experience and to provide context to the literature, "as if" they are standing over our shoulder and advising during a resuscitation. Additionally, there are three chapters where we address the medical-legal aspects of care. Enter Greg Henry MD, past president of The American College of Emergency Physicians (ACEP) and one of the most experienced physician medical-legal experts in the country. He opines on the approach that both the defense and plaintiff would likely pursue and, by extension, how we can make patients safer through our evaluation and documentation before there is an adverse outcome. Whereas, these chapters contain the actual documentation from the ED chart, a very few chapters have slight modifications to the final aspects of the return visit at decision point 3, to allow for exploration of different critical care scenarios. There is still plenty of commentary on the documentation, missed red-flags, and what could have been done to improve care at the initial visit. Our goal is to make each chapter challenging, dynamic, and realistic… to move us from “standard of care” to “excellence in care.” Book Review: "It's back, it's Bouncebacks! One of the mostly widely read and highly regarded education series in all of Emergency Medicine. Clinicians fear the medical malpractice landscape, but Mike Weinstock and the team give you all the tools you need to protect yourselves. Documentation people, documentation. Now with a critical care version. Read this book, sleep better at night, as simple as that! Love, love this series!" -- Mel Herbert, MD, MBBS, BMedSci, FACEP, FAAEMProfessor of Emergency Medicine at the Keck School of Medicine LAC + USC Medical Center, Owner and Editor of EM: RAP
This book is a guide for clinicians seeking to use metabolic approaches in the care of hospitalized patients. Since a nutritional component exists for practically any disease process managed, it is important to properly address the macro- and micronutrient issues that can help facilitate a favourable clinical outcome. Metabolic medicine is a newly recognized speciality that applies proven nutritional approaches to support hospitalized patients within existing standards of care. Optimizing Metabolic Status for the Hospitalized Patient: The Role of Macro- and Micronutrition on Disease Management addresses the gap of nutrition knowledge among physicians who generally care for patients without addressing the nutritional and metabolic perspective. Features: State-of-the-art guidelines for practicing metabolic medicine in the hospital setting “Hands on” guide for day-to-day metabolic management of hospitalized patients Personal insights from one of the field’s leading practitioners, drawing upon decades of experience Historical reviews of key scientific developments This book is written by Dr Michael M. Rothkopf, Clinical Professor of Medicine at Rutgers/New Jersey Medical School. Dr Rothkopf founded the Metabolic Medicine Center at Morristown Medical Center and is the current Metabolic Medicine Consultant for the Heart Transplant, Lung Transplant, Cardiac Surgery and Wound Care Programs at RWJBH/Newark Beth Israel Medical Center. This book is directed at the physician level of hospital care. It provides value to a broad range of physicians regardless of their medical specialty or subspecialty. It will also be useful for medical students and resident physicians in training as well as nurse practitioners and physician assistants working in hospital settings.
Looking for a brief but authoritative resource to help you manage the types of complex cardiac, pulmonary, and neurological emergencies you encounter as a resident or attending emergency room physician? Look no further than Decision Making in Emergency Critical Care: An Evidence-Based Handbook. This portable guide to rational clinical decision-making in the challenging – and changing – world of emergency critical care provides in every chapter a streamlined review of a common problem in critical care medicine, along with evidence-based guidelines and summary tables of landmark literature. Features Prepare for effective critical care practice in the emergency room’s often chaotic and resource-limited environment with expert guidance from fellows and attending physicians in the fields of emergency medicine, pulmonary and critical care medicine, cardiology, gastroenterology, and neurocritical care. Master critical care fundamentals as experts guide you through the initial resuscitation and the continued management of critical care patients during their first 24 hours of intensive care. Confidently make sustained, data-driven decisions for the critically ill patient using expert information on everything from hemodynamic monitoring and critical care ultrasonography to sepsis and septic shock to the ED-ICU transfer of care.
Pattern Theory provides a comprehensive and accessible overview of the modern challenges in signal, data, and pattern analysis in speech recognition, computational linguistics, image analysis and computer vision. Aimed at graduate students in biomedical engineering, mathematics, computer science, and electrical engineering with a good background in mathematics and probability, the text includes numerous exercises and an extensive bibliography. Additional resources including extended proofs, selected solutions and examples are available on a companion website. The book commences with a short overview of pattern theory and the basics of statistics and estimation theory. Chapters 3-6 discuss the role of representation of patterns via condition structure. Chapters 7 and 8 examine the second central component of pattern theory: groups of geometric transformation applied to the representation of geometric objects. Chapter 9 moves into probabilistic structures in the continuum, studying random processes and random fields indexed over subsets of Rn. Chapters 10 and 11 continue with transformations and patterns indexed over the continuum. Chapters 12-14 extend from the pure representations of shapes to the Bayes estimation of shapes and their parametric representation. Chapters 15 and 16 study the estimation of infinite dimensional shape in the newly emergent field of Computational Anatomy. Finally, Chapters 17 and 18 look at inference, exploring random sampling approaches for estimation of model order and parametric representing of shapes.
Brain Beat: A Scientific and Evolutionary Perspective of Brain Health examines the origins of the pillars of brain health, expounding the current scientific basis for recommending physical exercise, cognitive exercises, sleep hygiene, socialization and brain-foods. However in addition to the "how" question, the more important "why" question is addressed from a neuro-archeological and evolutionary standpoint. The clinical and laboratory brain sciences are replete with ever increasing numbers of p
Nestled in the Apennines, cradle of the Renaissance, home of Dante, Michelangelo, and the Medici, Florence is unlike any other city in its extraordinary mingling of great art and literature, natural splendor, and remarkable history. Intimate and grand, learned and engaging, Michael Levey's Florence renders the city in all of its madness and magnificence.
Based on the most current evidence and best practices, Perioperative Medicine: Managing for Outcome, 2nd Edition, is an easy-to-follow, authoritative guide to achieving optimal outcomes in perioperative care. Written and edited by recognized authorities in anesthesiology and surgical critical care, this fully updated edition helps you think critically about complex, long-term issues surrounding the care of the surgical patient, providing decision trees that define strategies to enhance the medical outcome of care. - Focuses on what anesthesiologists, surgeons, and intensivists need to know in order to improve outcomes through evidence- and outcome-based approaches. - Provides practical guidance on potential risks to all major organ systems, the etiology of particular organ dysfunctions, preoperative and intraoperative risk factors, and perioperative protection strategies to minimize potential complications. - Features a consistent chapter format - with even more color-coded algorithms, summary tables, and boxes – that enables you to quickly explore and determine the best management approaches. - Includes six all-new chapters: Perioperative Fluid Management; Delirium and POCD; Role of Palliative Care/ICU; Value-Based Care: The UK Model; CFO Perspective on Value; Hospital to Home (Perioperative Transitions of Care) - Discusses timely topics such as quality improvement, pay-for-performance, preexisting disease and comorbid conditions in anesthesiology, and the team-based model of care. - Features two new editors, surgeon Clifford Ko, MD, and Perioperative Summit leader, Michael (Monty) Mythen, MD.
Alcoholic liver disease has once again entered our collective conscience. A paper in 2012 showed the utility of orthotopic liver transplantation (OLT) in acute alcoholic hepatitis. As expected, this opened the floodgates. Every liver transplant program in the USA is now under pressure to list and transplant patients with alcoholic liver disease (ALD), resulting n a shift in the type of patients to admit and list for OLT. In consultation with Dr. Norman Gitlin, Dr. Norman Sussman and Dr. Michael Lucey have put together a collection of articles on current practices and future trends in the management of alcohol-related diseases. Expert authors from top institutions have contributed articles on the following topcs: Histopathology; Alcohol and the Law; Alcoholic Liver Disease in Children; Alcohol Use Disorder; Pathogenesis of ALD; Acute Alcoholic Hepatitis; Nutrition and Malnutrition in ALD; Alcoholic Cirrhosis; Liver Transplantation for Alcoholic Liver Disease; CNS effects of Alcohol; and Will Studies in NASH Help to Manage AS. Readers will come away with current clinical information to help them to make clinical decisions that will improve patient outcomes.
The two original volumes of the Encyclopedia of Catholic Social Thought, Social Science, and Social Policy were published in 2007. Those two volumes included 848 entries from nearly 300 contributors and included a wide range of entries in three general categories: entries exploring Catholic social thought at a theoretical level, entries reflecting the learning of various social science and humanistic disciplines as this learning relates to Catholic social thought, and entries examining specific social policy questions. This third, supplemental volume continues the approach of the original two. First, the volume includes entries that explore Catholic social thought at its broadest, most theoretical level; for example, an entry on Pope Benedict’s important social encyclical Caritas in Veritate. Second, the volume includes entries that discuss recent social science research that bears on issues important to Catholic social thought; for example, an entry on the social costs of pornography draws on recent research on the topic. Third, the volume includes entries discussing specific issues of social policy that have become increasingly important in recent years; for example, an entry on embryo adoption and/or rescue. This third volume contains 202 entirely new entries from over 100 contributors. The contributors include distinguished scholars such as Father Robert John Araujo, S.J. (Loyola University of Chicago), Father Kevin L. Flannery, S.J. (Gregorian University), Robert P. George (Princeton University), William E. May (John Paul Institute and the Culture of Life Foundation), D. Q. McInerny (Our Lady of Guadalupe Seminary), and Michael Novak (Ave Maria University). The work will appeal to anyone who is looking for a clear and accurate introduction to Catholic social thought.
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