In the next five years, excimer laser surgery will become the number-one growth area for all ophthalmologists. While much has been written about this exploding field, this new book is the first to deal exclusively with phototherapeutic keratectomy (PTK) and the advanced excimer procedures used to treat corneal disease. Excimer Laser Surgery combines guidelines for case selection, step-by-step instruction in PTK techniques, and coverage of operative complications - all supported by precise color photos and more than 30 case studies. The authors emphasize accurate diagnosis as the key to successful surgery and show which types of laser treatment are most appropriate for specific corneal disorders. Special features include: Complete information on all PTK procedures, accompanied by well-chosen operative cases and 128 illustrations A detailed, easy-to-use grid for matching your diagnosis to the right surgical treatment essential for the management of any corneal disorder Special chapter on the use of PTK to treat corneal haze, scarring, and other PRK-related complications. Strategies for reducing refractive changes in the course of PTK surgery A thorough review of recent clinical trials A complete, one-source guide to PTK, this book is essential for physicians who wish to expand their skills and become proficient in the full range of excimer procedures.
It is well established that glial cells represent more than mere passive cytoskeletal support elements of the central and peripheral nervous system. A reciprocal relationship exists between neurons and glia that is vital for mutual differentiation, development, and functioning of both cell types. It also has become apparent that perturbations in glial function may lead to deleterious consequences in juxtaposed neurons. It is therefore possible that neuronal damage induced by chemicals or neuropathic disease involves dissociation of glial-neuronal interactions. The Role of Glia in Neurotoxicity brings together experts in the neurosciences to provide a more complete understanding of the effects of chemicals on nervous system function. This book explores potential sites of glial-neuronal interactions both in the central and peripheral nervous system, focusing on potential sites of neurotoxicant actions. Text introduces basic aspects of neuroscience, the first step toward understanding the mechanisms at work in normal physiology. The ways in which these processes are disturbed in pathological conditions are discussed. Distinguished authors examine the functional interactions between glial cells and neurons during development, adulthood, and senescence. The roles of glia in the normal CNS and PNS are described. The book offers specific, in-depth examples of directly (via diffusive and cell surface signals) or indirectly (via effects on the extracellular fluid or the blood-brain barrier) mediated glial neurotoxicity. This reference includes different techniques, conceptual frameworks, and approaches that are currently used in the study of the role of glia in neurotoxicity. This timely review not only presents an excellent overview of the state of the science but also provides direction for future research into the consequences of an altered glial-neuronal unit.
The third edition of this book provides comprehensive coverage of pediatric medical adherence, including such important topics as the extent of nonadherence and medical consequences, predictors of adherence, theories about adherence and clinical applications, and assessment strategies for adherence and health outcomes. In addition, chapters describe strategies for improving adherence, review research studies on improving adherence, and address ways to improve research on adherence for children and adolescents with chronic diseases. The new edition also examines the developmental aspects of adherence assessment and intervention as well as cultural, ethical, and legal issues in adherence research and practice. Key areas of coverage include: Consequences of nonadherence and correlates of adherence. Developmental aspects related to assessing and improving pediatric medical adherence. Assessing pediatric disease and health status. Cultural, ethical, and legal issues related to pediatric medical adherence. Adherence to Pediatric Medical Regimens, Third Edition, is an essential reference for researchers, professors, and graduate students as well as clinicians, therapists, and other practitioners in developmental, clinical child and school psychology, child and adolescent psychiatry, pediatrics and pediatric psychology, social work, public health, health psychology, and all interrelated fields.
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