This issue of Medical Clinics, guest edited by Drs. Jeffrey H. Samet, Patrick G. O'Connor, and Michael D. Stein, is devoted to Substance Use and Addiction Medicine. Articles in this outstanding issue include: Making Unhealthy Substance Use a Part of Behavioral Health Integration in Primary Care; The Inpatient Addiction Consult Medical Service: Expertise for Hospitalized Patients with Complex Addiction Problems; The Addiction Physician Workforce: Addiction Psychiatry and Addiction Medicine Collaboration in a New Age; Preventing Opioid Overdose in the Clinic and Hospital: Analgesia and Opioid Antagonists; The Role of Non-Traditional Maintenance Treatments: Injectable Opioid Agonist Therapies and Managed Alcohol Programs; Office-Based Addiction Treatment (OBAT) in Primary Care: Models that Work; Alcohol Use Disorder Pharmacotherapy: the Use of FDA and non-FDA Approved Medications; When and How to Treat Possible Cannabis Use Disorder; Clinical Presentations of New Drugs with Abuse Potential; Use of Technology in Addiction Therapy; Sleep Management Among Patients with Substance Use Disorders; Pain Management Among Patients with Substance Use Disorders; E-Cigarettes: A Path to Recovery or a Road to Hell?; Are Adolescent and Young Adults Different When Addressing Substance Use Disorders?; and Smoking Cessation for Those in Recovery from Substance Use Disorders.
Carrying on the tradition established by its founding editor, the late Dr. Martin Abeloff, the 4th Edition of this respected reference synthesizes all of the latest oncology knowledge in one practical, clinically focused, easy-to-use volume. It incorporates basic science, pathology, diagnosis, management, outcomes, rehabilitation, and prevention – all in one convenient resource – equipping you to overcome your toughest clinical challenges. What's more, you can access the complete contents of this Expert Consult title online, and tap into its unparalleled guidance wherever and whenever you need it most! Equips you to select the most appropriate tests and imaging studies for diagnosing and staging each type of cancer, and manage your patients most effectively using all of the latest techniques and approaches. Explores all of the latest scientific discoveries' implications for cancer diagnosis and management. Employs a multidisciplinary approach - with contributions from pathologists, radiation oncologists, medical oncologists, and surgical oncologists - for well-rounded perspectives on the problems you face. Offers a user-friendly layout with a consistent chapter format • summary boxes • a full-color design • and more than 1,445 illustrations (1,200 in full color), to make reference easy and efficient. Offers access to the book's complete contents online – fully searchable – from anyplace with an Internet connection. Presents discussions on cutting-edge new topics including nanotechnology, functional imaging, signal transduction inhibitors, hormone modulators, complications of transplantation, and much more. Includes an expanded color art program that highlights key points, illustrates relevant science and clinical problems, and enhances your understanding of complex concepts.
The global humanitarian movement, which originated within Western religious organizations in the early nineteenth century, has been of most important forces in world politics in advancing both human rights and human welfare. While the religious groups that founded the movement originally focused on conversion, in time more secular concerns came to dominate. By the end of the nineteenth century, increasingly professionalized yet nominally religious organization shifted from reliance on the good book to the public health manual. Over the course of the twentieth century, the secularization of humanitarianism only increased, and by the 1970s the movement's religious inspiration, generally speaking, was marginal to its agenda. However, beginning in the 1980s, religiously inspired humanitarian movements experienced a major revival, and today they are virtual equals of their secular brethren. From church-sponsored AIDS prevention campaigns in Africa to Muslim charity efforts in flood-stricken Pakistan to Hindu charities in India, religious groups have altered the character of the global humanitarian movement. Moreover, even secular groups now gesture toward religious inspiration in their work. Clearly, the broad, inexorable march toward secularism predicted by so many Westerners has halted, which is especially intriguing with regard to humanitarianism. Not only was it a highly secularized movement just forty years ago, but its principles were based on those we associate with "rational" modernity: cosmopolitan one-worldism and material (as opposed to spiritual) progress. How and why did this happen, and what does it mean for humanitarianism writ large? That is the question that the eminent scholars Michael Barnett and Janice Stein pose in Sacred Aid, and for answers they have gathered chapters from leading scholars that focus on the relationship between secularism and religion in contemporary humanitarianism throughout the developing world. Collectively, the chapters in this volume comprise an original and authoritative account of religion has reshaped the global humanitarian movement in recent times.
Paleomagnetism is the study of the fossil magnetism in rocks. It has been paramount in determining that the continents have drifted over the surface of the Earth throughout geological time. The fossil magnetism preserved in the ocean floor has demonstrated how continental drift takes place through the process of sea-floor spreading. The methods and techniques used in paleomagnetic studies of continental rocks and of the ocean floor are described and then applied to determining horizontal movements of the Earth's crust over geological time. An up-to-date review of global paleomagnetic data enables 1000 million years of Earth history to be summarized in terms of the drift of the major crustal blocks over the surface of the Earth. The first edition of McElhinny's book was heralded as a "classic and definitive text." It thoroughly discussed the theory of geomagnetism, the geologic reversals of the Earth's magnetic field, and the shifting of magnetic poles. In the 25 years since the highly successful first edition of Palaeomagnetism and Plate Tectonics (Cambridge, 1973) the many advances in the concepts, methodology, and insights into paleomagnetism warrant this new treatment. This completely updated and revised edition of Paleomagnetism: Continents and Oceans will be a welcome resource for a broad audience of earth scientists as well as laypeople curious about magnetism, paleogeography, geology, and plate tectonics. Because the book is intended for a wide audience of geologists, geophysicists, and oceanographers, it balances the mathematical and descriptive aspects of each topic. - Details the theory and methodology of rock magnetism, with particular emphasis on intrepreting crustal movements from continental and oceanic measurements - Outlines Earth history for the past 1000 million years, from the Rodinia super-continent through its breakup and the formation of Gondwana to the formation and breakup of Pangea and the amalgamation of Eurasia - Provides a comprehensive treatment of oceanic paleomagnetism - Provides a set of color pateogeographic maps covering the past 250 million years - Written by two internationally recognized experts in the field
A POLITICAL PROVOCATION FROM A PAIR OF PHYSICIANS WRITING OUTSIDE THEIR LANE In Pained, physicians Michael Stein and Sandro Galea push the conversation around American health where it belongs: toward matters of class, money, and culture. Across more than 50 essays and data illustrations, Pained casts a light on how the structural components of everyday life -- matters like school, housing, police, even cell phones -- ultimately determine who gets to be healthy in today's America. In doing so, it makes a case for reframing our political discourse in less myopic, more effectual terms.
For 25 years, Lewis's Child and Adolescent Psychiatry has been the cornerstone of every child and adolescent psychiatrist’s library. Now, three colleagues of Dr. Lewis at the world-renowned Yale Child Study Center, have substantially updated and revised this foundational textbook for its long-awaited fifth edition, the first in ten years. Encyclopedic in scope, it continues to serve as a broad reference, deftly encompassing and integrating scientific principles, research methodologies, and everyday clinical care.
Volume II of two, from the Thermodymaics Research Centre, this includes Thermodynamic Functions of the Substances in the Ideal Gas State; and Empirical Functions for Thermodynamical Properties of Ideal Gases.
AIDS treatments continues to evolve. Now, so does the definitive reference on this complex and challenging subject! "AIDS Therapy, 3rd Edition" not only brings you comprehensive guidance on the latest treatments for HIV/AIDS and the full range of related disorders and syndromes, but also comes with access to updates online—so you can always tap into the most current therapy guidelines. Written by a "who's who" of leading global experts, the new edition of this classic reference is a must for any clinician who manages patients with HIV/AIDS. The most comprehensive coverage available on AIDS treatment equips you to meet any clinical challenge. Contributions from a large cast of noted international authorities put global "best practices" at your fingertips. Advice from some of the most respected experts in the field helps you manage your patients confidently. Available with a companion website allowing you to access the latest treatment guidelines year after year.
This book critiques current assumptions about 'communication', particularly digitally mediated communication, by re-examining conceptual foundations in rhetoric, linguistics, semiotics, information theory, and cybernetics. The result is a dimensional account of interaction that is at once both intuitive and revolutionary.
50 Imaging Studies Every Doctors Should Know presents summaries of key studies that have shaped the current clinical practice of radiology. Numerous topics are covered including: headache, back pain, chest pain, abdominal and pelvic pain, bone, joint, and extremity pain, cancer screening and management, and radiation exposure from medical imaging. An illustrative clinical case and radiologic image conclude each review, followed by brief information on other relevant studies.
From drilling holes into the skulls of prisoners, to solitary confinement, to deploying a range of psychological therapies, society has attempted to deal with the problem of criminals in myriad ways over the last few centuries. This analytical history explores the ever-changing approaches to punishing wrongdoers and preventing further offenses, the philosophical beliefs underlying them, and their relative effects. It discusses such core issues as the role of free will and determination, the root causes of crime, and the effects of studying crimes versus studying criminals. It highlights the continuous debate regarding rehabilitation and punishment, the history of biologically and psychologically based treatments, and the principles of effective intervention, concluding with discussion of what lies ahead.
Personal property security is an important subject in commercial practice as it is the key to much of the law of banking and sale. This book examines traditional methods of securing debts (such as mortgages, charges and pledges as well as so-called 'quasi-security') on property other than land, describing how these are created, how they must be registered (or otherwise 'perfected') if they are to be valid, the rights and duties of the parties and how the security is enforced if the debt is not paid. This fourth edition has been updated to incorporate recent political and legal developments, including Brexit. The 'Edinburgh Reforms', which have followed the United Kingdom's exit from the European Union, promise a thorough overhaul of the consumer credit regime. The Retained EU Law (Revocation and Reform) Act 2023 potentially affects the interpretation of EU assimilated law, including the Financial Collateral Arrangements (No2) Regulations (FCARs). This edition further assesses the implications of the Business Contract Terms (Assignment of Receivables) Regulations 2018, taking pledges over electronic documents of title in the light of the Electronic Trade Documents Act 2023, the outlawing of 'ipso facto' clauses by the Corporate Insolvency and Governance Act 2020, and the reduced scope of the EU Insolvency Regulation. The treatment of insolvency matters within the framework of the Cape Town Convention is also considered, as are recent cases on pledges of bills of lading when the carrier no longer has possession of the goods, the distinction between fixed and floating charges, equitable liens and the right of appropriation of financial collateral. There is a full discussion of the taking of security over digital assets and the relevance of the FCARs. The only full-length treatment covering both traditional security over personal property and also devices that fulfil a similar economic function, such as retention of title and sales of receivables, The Law of Security and Title-Based Financing is a frequently-cited and indispensable reference work both for practitioners and academics.
Innovations and Challenges in Grammar traces the history of common understandings of what grammar is and where it came from to demonstrate how ‘rules’ are anything but fixed and immutable. In doing so, it deconstructs the notion of ‘correctness’ to show how grammar changes over time thereby exposing the social and historical forces that mould and change usage. The questions that this book grapples with are: Can we separate grammar from the other features of the language system and get a handle on it as an independent entity? Why should there be strikingly different notions and models of grammar? Are they (in)compatible? Which one or ones fit(s) best the needs of applied linguists if we assume that applied linguists address real-world problems through the lens of language? And which one(s) could make most sense to non-specialists? If grammar is not a fixed entity but a set of usage norms in constant flux, how can we persuade other professionals and the general public that this is a positive observation rather than a threat to civilised behaviour? This book draws upon both historical and modern grammars from across the globe to provide a multi-layered picture of world grammar. It will be useful to teachers and researchers of English as a first and second language, though the inclusion of examples from and occasional references to other languages (French, Spanish, Malay, Swedish, Russian, Welsh, Burmese, Japanese) is intended to broaden the appeal to teachers and researchers of other languages. It will be of use to final-year undergraduate, postgraduate and doctoral students as well as secondary and tertiary level teachers and researchers in applied linguistics, second language acquisition and grammar pedagogy.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
25 ADDITIONAL CHAPTERS AVAILABLE ONLINE THE LANDMARK TEXT ON HOW TO ACHIEVE OPTIMAL PATIENT OUTCOMES THROUGH EVIDENCE-BASED MEDICATION THERAPY Pharmacotherapy: A Pathophysiologic Approach is written to help you advance the quality of patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. The scope of this trusted classic goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. You will find everything you need to provide safe, effective drug therapy across the full range of therapeutic categories. This edition is enriched by more than 300 expert contributors, and every chapter has been revised and updated to reflect the latest evidence-based information and recommendations. Important features such as Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy make this text an essential learning tool for students, patient-focused pharmacists, and other health care providers. NEW TO THIS EDITION: A section on personalized pharmacotherapy appears in most sections All diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches have been updated in full color to clearly distinguish treatment pathways New drug monitoring tables have been added Most of the disease-oriented chapters have incorporated evidence-based treatment guidelines that often include ratings of the level of evidence to support the key therapeutic approaches Twenty-five online-only chapters are available at www.pharmacotherapyonline.com
Surveying print and digital graphic life narratives about people who become 'othered' within Western contexts, this book investigates how comics and graphic novels witness human rights transgressions in contemporary Anglophone culture and how they can promote social justice. With thought given to how the graphic form can offer a powerful counterpoint to the legal, humanitarian and media discourses that dehumanise the most violated and dispossessed, but also how these works may unconsciously reproduce Western neo-colonial presentations of the 'other,' Olga Michael focuses on gender, death, space, and border violence within graphic life narratives depicting suffering across different geo- and biopolitical locations. Combining the familiar with the lesser-known, this book covers works by artists such as Joe Sacco, Thi Bui, Mia Kirshner, Phoebe Gloeckner, Kamel Khélif, Francesca Sanna, Gabi Froden, Benjamin Dix and Lindsay Pollock, as well as Safdar Ahmed and Ali Dorani/Eaten Fish. Interdisciplinary in its consideration of life writing, comics and human rights studies, and comparative in approach, this book explores such topics as the aesthetics of visualised suffering; spatial articulations of human rights violations; the occurrence of violations whilst crossing borders; the gendered dimensions of visually captured violence; and how human rights discourses intersect with graphic depictions of the dead. In so doing, Michael establishes how to read human rights and social justice comics in relation to an escalating global crisis and deftly complicates negotiations of 'otherness.' A vitally important work to the humanities sector, this book underscores the significance of postcolonial decolonized reading acts as forms of secondary witness.
Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders. As a result many previously unrecognised disorders have been charac terised. Some clinical syndromes, such as the limb girdle dystrophies, have become better defined. In many such instances the new genetic information has led to major advances in knowledge of the biology of cell structures, for example, the membrane structural and channel proteins. The clinical syndromes themselves, and their patho logical and electrophysiological characteristics, however, remain as important as ever, since they constitute the clinical problem itself and, indeed, the database from which all other concepts emerge. Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. However, this informa tion does not necessarily always define clinically useful syndromes. Myotonia, for example, is an electrophysiological finding in some syndromes in which it is un detectable by clinical examination, although the phenomenon itself was originally defined as a clinical entity. The limb girdle muscular dystrophy syndromes can be defined by severity, distribution of weakness, age of onset, sex distribution and other characteristics and many of these can be better understood by study of the under lying defect in cell structural proteins.
The first book of its kind to focus on the diagnosis, prevention, and treatment of patients with fungal infections, this definitive reference returns in a completely revised, full-color new edition. It presents specific recommendations for understanding, controlling, and preventing fungal infections based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. More than 560 photographs, illustrations, and tables depict conditions as they appear in real life and equip you to identify clinical manifestations with accuracy. Expanded therapy content helps you implement the most appropriate treatment quickly, and a bonus CD-ROM-featuring all of the images from the text-enables you to enhance your electronic presentations. Includes specific recommendations for diagnosing, preventing, and treating fungal infections in various patient populations based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. Covers etiologic agents of disease, fungal infections in special hosts such as pediatric patients and patients with cancer and HIV, infections of specific organ systems, and more, to make you aware of the special considerations involved in certain cases. Features clinically useful and reader-friendly practical tools-including algorithms, slides, graphs, pictorials, photographs, and radiographs-that better illustrate and communicate essential points, promote efficient use in a variety of clinical and academic settings, and facilitate slide making for lectures and presentations. Offers a CD-ROM containing all of the book's images for use in your electronic presentations. Offers more clinically relevant images-more than 300 in full color for the first time-to facilitate diagnosis. Features expanded therapy-related content, including up-to-date treatment strategies and drug selection and dosing guidelines. Includes several new sections in the chapter on fungal infections in cancer patients that reflect the formidable clinical challenges these infections continue to present. Presents the work of additional international contributors who have defined many of the key issues in the field, providing more of a global perspective on the best diagnostic and management approaches. Uses a new, full-color design to enhance readability and ease of access to information.
All forms of psychotherapy deal with the limitations of our awareness. This book offers a comprehensive overview of the ways in which these discourses employ a rich variety of concepts to address the limits of our everyday consciousness.
An engaging introduction to marine chemistry and the ocean's geochemical interactions with the solid earth and atmosphere, for students of oceanography.
We will all be patients sooner or later. And when we go to the doctor, when we're hurting, we tend to think in terms of cause and condemnation. We often look for relief not only from physical symptoms but also from our self-blame. We want from our doctors kindness under any of its many names: empathy, caring, compassion, humanity. We look for safety and forgiveness. But we forget that doctors, too, are often in need of forgiveness—from their patients and from themselves. No doctor enters the medical profession expecting to be unkind or to make mistakes, but because of the complexity of our current medical system and because doctors are human, they often find themselves acting much less kindly than they would like to. Drawing on his work as a primary care physician and a behavioral scientist, Michael Stein artfully examines the often conflicting goals of patients and their doctors. In those differences, Stein recognizes that kindness should not be a patient's forbidden or unrealistic expectation. This book leaves us with new knowledge of and insights into what we might hope for, and what might go wrong, or right, in the most intimate clinical moments.
Bioinformatics, Biocomputing and Perl presents a modern introduction to bioinformatics computing skills and practice. Structuring its presentation around four main areas of study, this book covers the skills vital to the day-to-day activities of today’s bioinformatician. Each chapter contains a series of maxims designed to highlight key points and there are exercises to supplement and cement the introduced material. Working with Perl presents an extended tutorial introduction to programming through Perl, the premier programming technology of the bioinformatics community. Even though no previous programming experience is assumed, completing the tutorial equips the reader with the ability to produce powerful custom programs with ease. Working with Data applies the programming skills acquired to processing a variety of bioinformatics data. In addition to advice on working with important data stores such as the Protein DataBank, SWISS-PROT, EMBL and the GenBank, considerable discussion is devoted to using bioinformatics data to populate relational database systems. The popular MySQL database is used in all examples. Working with the Web presents a discussion of the Web-based technologies that allow the bioinformatics researcher to publish both data and applications on the Internet. Working with Applications shifts gear from creating custom programs to using them. The tools described include Clustal-W, EMBOSS, STRIDE, BLAST and Xmgrace. An introduction to the important Bioperl Project concludes this chapter and rounds off the book.
The landmark text on how to achieve optimal patient outcomes through evidence-based medication therapy Pharmacotherapy: A Pathophysiologic Approach is written to help you advance the quality of patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. The scope of this trusted classic goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. You will find everything you need to provide safe, effective drug therapy across the full range of therapeutic categories. This edition is enriched by more than 300 expert contributors, and every chapter has been revised and updated to reflect the latest in evidence-based information and recommendations. Important features such as Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy make this text an essential learning tool for students, patient-focused pharmacists, and other health care providers. NEW TO THIS EDITION A section on personalized pharmacotherapy appears in most sections All diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches have been updated in full color to clearly distinguish treatment pathways New drug monitoring tables have been added Most of the disease-oriented chapters have incorporated evidence-based treatment guidelines that when available, include ratings of the level of evidence to support the key therapeutic approaches Twenty-four online-only chapters
A Doody's Core Title for 2023! The #1 Textbook in Pharmacotherapy providing optimal patient outcomes using evidence-based medication therapies—updated with the latest advances and guidelines For more than 30 years, DiPiro’s Pharmacotherapy has been the essential textbook for learning how to properly select, administer, and monitor drugs―everything needed to provide safe, effective drug therapy across all therapeutic categories. This new edition has been fully updated with the latest evidence-based information and recommendations. With content from 300 expert contributors, this valuable resource offers detailed descriptions of common and uncommon disease states, including treatment by pharmacologic and non-pharmacologic means. Each disease chapter opens with a Patient Care Process, helping readers understand the collaborative care model in which pharmacists work and communicate with other healthcare providers for effective coordinated care. Here's why DiPiro's Pharmacotherapy: A Pathophysiologic Approach is the perfect learning tool for students, pharmacists, and other healthcare providers: All chapters provide the most current, reliable, and relevant information available Key concepts are included at the beginning of each chapter Clinical Presentation boxes concisely outline disease signs and symptoms New: Beyond the Book feature points readers to multimedia resources to deepen their understanding of the material Diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches clearly distinguish treatment pathways New: Drug monitoring tables have been added Patient care process boxes help readers know how to communicate with other health care providers New: Additional FREE E-Chapters are available on AccessPharmacy New: Over 2000 Review Questions to help prepare students!
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