From drilling holes into the skulls of prisoners, to solitary confinement, to deploying a range of psychological therapies, society has attempted to deal with the problem of criminals in myriad ways over the last few centuries. This analytical history explores the ever-changing approaches to punishing wrongdoers and preventing further offenses, the philosophical beliefs underlying them, and their relative effects. It discusses such core issues as the role of free will and determination, the root causes of crime, and the effects of studying crimes versus studying criminals. It highlights the continuous debate regarding rehabilitation and punishment, the history of biologically and psychologically based treatments, and the principles of effective intervention, concluding with discussion of what lies ahead.
The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Winner of the Textbook & Acadmic Authors Association 2021 McGuffey Longevity Award.
“Drs. Smolak and Levine are to be congratulated for this timely, comprehensive two-volume Handbook. The list of contributors is impressive, the breadth of topics covered is exhaustive, and the overall organization is superb.” James E. Mitchell, MD, Christoferson Professor and Chair of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences, President and Scientific Director, The Neuropsychiatric Research Institute “Unquestionably, the most comprehensive overview of eating disorders in the history of the field, edited by two of its most respected scholars. Drs. Smolak and Levine have recruited distinguished clinicians and researchers to review every aspect of these illnesses from prevention to treatment. This Handbook should be required reading for any professional that wants to work in this field.” Craig Johnson, PhD, FAED, Chief Science Officer, Eating Recovery Center, Clinical Professor of Psychiatry, University of Oklahoma College of Medicine “Eating disorders are serious public health problems. This comprehensive book on eating disorders is edited by two of the pioneers in the field, Drs. Linda Smolak and Michael Levine. Their work on topics such as eating disorders prevention, media and eating disorders, and the objectification of women have greatly informed our knowledge base and current practices. In this outstanding volume, Smolak and Levine pull together many of the leaders within the field of eating disorders. I strongly recommend this book to anyone with an interest in the etiology, consequences, prevention, or treatment of eating disorders.” Dianne Neumark-Sztainer, PhD, Professor, School of Public Health, University of Minnesota Author, “I’m, Like, So Fat!” Helping Your Teen Make Healthy Choices about Eating and Exercise in a Weight-Obsessed World “Renowned scholars Smolak and Levine have assembled the best scientists and clinicians to educate us about the major advances and important questions in the field of eating disorders. This comprehensive Handbook is a must-have, rich, and accessible resource.” Thomas F. Cash, PhD, Professor Emeritus of Psychology, Old Dominion University This groundbreaking two-volume Handbook, edited by two of the leading authorities on body image and eating disorders research, provides evidence-based analysis of the causes, treatment, and prevention of eating disorders. The Wiley Handbook of Eating Disorders features the most comprehensive and up-to-date collection of eating disorders research ever assembled, including contributions from an international group of scholars from a range of disciplines, as well as coverage of DSM-5. The Handbook includes chapters on history, etiological factors, diagnosis, assessment, treatment, prevention, social policy, and advocacy. Boldly tackling controversies and previously unanswered questions in the field, and including suggestions for further research at the conclusion of every chapter, The Wiley Handbook of Eating Disorders will be an essential resource for students, scholars, and clinicians invested in improving the treatment and prevention of eating disorders.
Designing application and middleware software to run in concurrent and networked environments is a significant challenge to software developers. The patterns catalogued in this second volume of Pattern-Oriented Software Architectures (POSA) form the basis of a pattern language that addresses issues associated with concurrency and networking. The book presents 17 interrelated patterns ranging from idioms through architectural designs. They cover core elements of building concurrent and network systems: service access and configuration, event handling, synchronization, and concurrency. All patterns present extensive examples and known uses in multiple programming languages, including C++, C, and Java. The book can be used to tackle specific software development problems or read from cover to cover to provide a fundamental understanding of the best practices for constructing concurrent and networked applications and middleware. About the Authors This book has been written by the award winning team responsible for the first POSA volume "A System of Patterns", joined in this volume by Douglas C. Schmidt from University of California, Irvine (UCI), USA. Visit our Web Page
Drawing on scientific evidence from medicine, psychology, criminology, and sociology, this book explores the veracity of claims about marijuana use and misuse. Is marijuana an innocent recreational pleasure and medicinal boon or an evil that must be outlawed to protect the American public? With the legal and social status of marijuana in transition, accurate and objective information regarding its use is necessary for informed decisionmaking in both the personal and political arenas. To distinguish truth from fiction, this book draws on scientific evidence from medicine, psychology, criminology, and sociology, exploring many of the most commonly held beliefs about marijuana and documenting the scope and impact of its use-and abuse-in the United States. The work is organized around five broad topics: patterns and trends; risks and benefits; causes and consequences; criminalization; and practice and policy. It opens with examinations of use and abuse trends among various U.S. subpopulations, then goes on to scrutinize claims about the medical risks associated with the substance. Social and interpersonal causes and consequences of marijuana use are addressed, as is the history and future of marijuana legislation in the United States. Readers will come away from this book with broad-based knowledge about marijuana-and a scientifically grounded understanding of the benefits and risks of marijuana use.
This book critiques current assumptions about 'communication', particularly digitally mediated communication, by re-examining conceptual foundations in rhetoric, linguistics, semiotics, information theory, and cybernetics. The result is a dimensional account of interaction that is at once both intuitive and revolutionary.
This issue of Medical Clinics, guest edited by Drs. Jeffrey H. Samet, Patrick G. O'Connor, and Michael D. Stein, is devoted to Substance Use and Addiction Medicine. Articles in this outstanding issue include: Making Unhealthy Substance Use a Part of Behavioral Health Integration in Primary Care; The Inpatient Addiction Consult Medical Service: Expertise for Hospitalized Patients with Complex Addiction Problems; The Addiction Physician Workforce: Addiction Psychiatry and Addiction Medicine Collaboration in a New Age; Preventing Opioid Overdose in the Clinic and Hospital: Analgesia and Opioid Antagonists; The Role of Non-Traditional Maintenance Treatments: Injectable Opioid Agonist Therapies and Managed Alcohol Programs; Office-Based Addiction Treatment (OBAT) in Primary Care: Models that Work; Alcohol Use Disorder Pharmacotherapy: the Use of FDA and non-FDA Approved Medications; When and How to Treat Possible Cannabis Use Disorder; Clinical Presentations of New Drugs with Abuse Potential; Use of Technology in Addiction Therapy; Sleep Management Among Patients with Substance Use Disorders; Pain Management Among Patients with Substance Use Disorders; E-Cigarettes: A Path to Recovery or a Road to Hell?; Are Adolescent and Young Adults Different When Addressing Substance Use Disorders?; and Smoking Cessation for Those in Recovery from Substance Use Disorders.
This sophisticated book argues that human rights literature both helps the persecuted to cope with their trauma and serves as the foundation for a cosmopolitan ethos of universal civility—a culture without borders. Michael Galchinsky maintains that, no matter how many treaties there are, a rights-respecting world will not truly exist until people everywhere can imagine it. The Modes of Human Rights Literature describes four major forms of human rights literature: protest, testimony, lament, and laughter to reveal how such works give common symbolic forms to widely held sociopolitical emotions.
The subject of this book is Complex Analysis in Several Variables. This text begins at an elementary level with standard local results, followed by a thorough discussion of the various fundamental concepts of "complex convexity" related to the remarkable extension properties of holomorphic functions in more than one variable. It then continues with a comprehensive introduction to integral representations, and concludes with complete proofs of substantial global results on domains of holomorphy and on strictly pseudoconvex domains inC", including, for example, C. Fefferman's famous Mapping Theorem. The most important new feature of this book is the systematic inclusion of many of the developments of the last 20 years which centered around integral representations and estimates for the Cauchy-Riemann equations. In particu lar, integral representations are the principal tool used to develop the global theory, in contrast to many earlier books on the subject which involved methods from commutative algebra and sheaf theory, and/or partial differ ential equations. I believe that this approach offers several advantages: (1) it uses the several variable version of tools familiar to the analyst in one complex variable, and therefore helps to bridge the often perceived gap between com plex analysis in one and in several variables; (2) it leads quite directly to deep global results without introducing a lot of new machinery; and (3) concrete integral representations lend themselves to estimations, therefore opening the door to applications not accessible by the earlier methods.
The first book on Prognostics and Health Management of Electronics Recently, the field of prognostics for electronic products has received increased attention due to the potential to provide early warning of system failures, forecast maintenance as needed, and reduce life cycle costs. In response to the subject's growing interest among industry, government, and academic professionals, this book provides a road map to the current challenges and opportunities for research and development in Prognostics and Health Management (PHM). The book begins with a review of PHM and the techniques being developed to enable a prognostics approach for electronic products and systems. building on this foundation, the book then presents the state of the art in sensor systems for in-situ health and usage monitoring. Next, it discusses the various models and algorithms that can be utilized in PHM. Finally, it concludes with a discussion of the opportunities in future research. Readers can use the information in this book to: Detect and isolate faults Reduce the occurrence of No Fault Found (NFF) Provide advanced warning of system failures Enable condition-based (predictive) maintenance Obtain knowledge of load history for future design, qualification, and root cause analysis Increase system availability through an extension of maintenance cycles and/or timely repair actions Subtract life cycle costs of equipment from reduction in inspection costs, down time, and inventory Prognostics and Health Management of Electronics is an indispensable reference for electrical engineers in manufacturing, systems maintenance, and management, as well as design engineers in all areas of electronics.
“The 1931 murder of 'Broadway Butterfly' Vivian Gordon exposed an explosive story of graft, corruption and entrapment that went all the way to the top of the state. Wolraich brings a journalist’s eye and a novelist’s elegance to this story of Jazz Age New York.”—New York Times Vivian Gordon went out before midnight in a velvet dress and mink coat. Her body turned up the next morning in a desolate Bronx park, a dirty clothesline wrapped around her neck. At her stylish Manhattan apartment, detectives discovered notebooks full of names—businessmen, socialites, gangsters. And something else: a letter from an anti-corruption commission established by Governor Franklin Delano Roosevelt. Led by the imperious Judge Samuel Seabury, the commission had uncovered a police conspiracy to frame women as prostitutes. Had Vivian Gordon been executed to bury her secrets? As FDR pressed the police to solve her murder, Judge Seabury pursued the trail of corruption to the top of Gotham’s powerful political machine—the infamous Tammany Hall.
This book is an excellent resource for students, educators, and long-term care administrators. This engaging eighth edition provides useful knowledge and up-to-date information to all those interested in long-term care management." --Doody's Review Service, 5 stars Now in its eighth edition, Nursing Home Administration remains the authoritative textbook detailing the nursing facility administrator role, what they do, how they think, and how they lead. By breaking down the art of administration into its basic, need-to-know tasks—forecasting, planning, organizing, staffing, directing, controlling quality, innovating, and marketing—this text provides the essential context for managing and leading nursing homes and skilled nursing facilities. Thoroughly updated to include the four domains of practice as put forth by the National Association of Long-Term Care Administrator Boards (NAB) for 2022 licensure examination and beyond, this textbook is complete with essential context for the domains and associated competencies to better prepare students for the required NAB examination. With revised sections addressing new federal regulations and laws affecting the field, best practices in residential care, and refreshed examples and cases, this text continues to set students up for success in working as a nursing facility administrator. Updated sections address changes within the residential care continuum, provide further information on patient-driven payment models and value-based care, and inform current practices for marketing and controlling quality within the long-term care facility. Chapter boxes reflect common pitfalls in practice while real-life case studies and critical thinking exercises, including a "What Do I Do Now?" section that concludes all chapters, encourage students to consider challenges they may experience in the field. In addition to updated domains of practice—care, services, and supports; operations; environmental and quality; and leadership and strategy—the book describes how core components fit together. New to the Eighth Edition: Includes the updated 2022 domains of practice as they relate to the licensing examination standards of the National Association of Long-Term Care Administrator Boards (NAB) Replete with information on new federal laws, requirements, and regulations including links to important resources such as the Minimum Data Set 3.0 Provides insight into the impact the COVID-19 pandemic has and will create for managing a long-term care facility Introduces Common Pitfalls in Practice sections and "What Do I Do Now?" boxes in each chapter, designed to spark critical thinking and discussion Updated figures, tables, and references throughout Key Features: Provides an in-depth discussion of nursing facility administration Utilizes current data of nursing facility administration and skilled nursing care within the context of the larger long-term care field Case studies throughout the textbook address real-world situations and experiences for administrators and managers in nursing facility administration and skilled nursing care Purchase includes digital access for use on most mobile devices or computers Qualified Instructors can gain access to the book's accompanying Instructor's Manual
Provides important new content on specific ethical, leadership, and advocacy capabilities that advance the DNP role in nursing practice This core text for the DNP curriculum encompasses all facets of the evolving advanced practice role including diverse professional opportunities and options for career advancement. With ten completely new chapters, the third edition conveys the latest developments in doctoral-level capabilities, including the specific ethical, leadership, and advocacy components that advance these roles. New content addresses health equity, role negotiation, ethical and leadership dilemmas for the clinician, and the preceptor role in relation to doctoral-level advanced practice. Considering the predominance of students seeking the Nurse Practitioner role, the book emphasizes the clinical context for the DNP along with the new AACN Domain of Professionalism. There also are contributions from Nurse Midwives, Nurse Anesthetists, Clinical Nurse Specialists, and DNPs in the Nurse Educator role. The text is distinguished by distinctive Reflective Responses to the authors of all chapters. These may be characterized as a Point-Counterpoint feature—consisting of commentaries by scholars of varying points of view—that stimulates substantive critical dialogue. It examines the role of evidence—both practice-based evidence and evidence-based practice—in the context of clinical problems and policy formation and focuses on how the doctoral advanced prepared nurse can discriminate, translate, and sometimes generate new nursing evidence. The text addresses the need for both forms of evidence and underscores the importance of innovative healthcare intervention models. Included is practical information illustrated with examples geared for both BSN-DNP students and MSN-DNP students. Content on the DNP/PhD double doctorate and the impact of DNP leadership on organizations further examines the relationship between nursing practice, education, and science. New to the Third Edition: Ten new chapters, including coverage of: COVID-19; BSN-DNP Trajectories; Practice-Based Evidence and Evidence-Based Practice; Health Equity; Role Negotiation, Ethical, Leadership, and Advocacy Roles; and 2021 AACN Essentials Expanded roles and content for students of varying experience levels Emphasis on the new AACN Domain of Professionalism throughout Key Features: Focuses on DNP role development with extensive contributions by leading DNP scholars and clinicians Delivers Reflective Responses in a Point-Counterpoint format to stimulate vigorous class discussion Provides critical thinking questions throughout including Reflective Response
Providing care for a young adult with type 1 diabetes during this stage can be difficult as well. Transitions in Care serves as a coaching manual for health care providers and parents, and as a guide to self-care and independence for young adults with diabetes. It demystifies a complicated period in a life with type 1 diabetes and makes the passage to adulthood easier for everyone involved.
All forms of psychotherapy deal with the limitations of our awareness. We have limited knowledge of our creative potential, of the details of our own behaviour, of our everyday emotional states, of what motivates us, and of the many factors within and around us which influence the decisions we make and the ways we act. Some therapists, especially those influenced by Freud and Jung, speak of the 'unconscious', giving the unintended impression that it is a kind of realm or domain of activity. Others, reacting against the specifics of Freudian theory, shun the word 'unconscious' altogether. However, so limited is the reach of everyday awareness and such is the range of unconscious factors, that one way or another these limitations must somehow be spoken about, sometimes in metaphor, sometimes more explicitly. This book offers a broad survey of psychotherapy discourses, including: The psychoanalytic The interpersonal The experiential The cognitive-behavioural The transpersonal This book offers a comprehensive overview of the ways in which these discourses employ a rich variety of concepts to address the limits of our everyday consciousness. Conscious and Unconscious is invaluable reading for all those interested in counselling and psychotherapy, including those in training, as well as for experienced therapists.
Buffalo's appreciation for a frosty pint stretches back more than a century before anyone enjoyed a cold one with a basket of wings. By the middle of the 1800s, the industrial hub counted malt and beer among its most vital and satisfying products. Operations like Simon Pure Beer, Iroquois Beverage and the Magnus Beck Brewing Company brought Buffalo's world-class ales to the rest of the country. Prohibition saw a thriving business in black market hooch, though it all but killed the city's historic breweries. A few survivors struggled to recover. Today, a new batch of breweries like Community Beer Works and Big Ditch Brewing Company are crafting a beer revolution in the Queen City. Historian Michael Rizzo and brewer Ethan Cox explore the sudsy story of Buffalo beer.
Personal property security is an important subject in commercial practice as it is the key to much of the law of banking and sale. This book examines traditional methods of securing debts (such as mortgages, charges and pledges as well as so-called 'quasi-security') on property other than land, describing how these are created, how they must be registered (or otherwise 'perfected') if they are to be valid, the rights and duties of the parties and how the security is enforced if the debt is not paid. This fourth edition has been updated to incorporate recent political and legal developments, including Brexit. The 'Edinburgh Reforms', which have followed the United Kingdom's exit from the European Union, promise a thorough overhaul of the consumer credit regime. The Retained EU Law (Revocation and Reform) Act 2023 potentially affects the interpretation of EU assimilated law, including the Financial Collateral Arrangements (No2) Regulations (FCARs). This edition further assesses the implications of the Business Contract Terms (Assignment of Receivables) Regulations 2018, taking pledges over electronic documents of title in the light of the Electronic Trade Documents Act 2023, the outlawing of 'ipso facto' clauses by the Corporate Insolvency and Governance Act 2020, and the reduced scope of the EU Insolvency Regulation. The treatment of insolvency matters within the framework of the Cape Town Convention is also considered, as are recent cases on pledges of bills of lading when the carrier no longer has possession of the goods, the distinction between fixed and floating charges, equitable liens and the right of appropriation of financial collateral. There is a full discussion of the taking of security over digital assets and the relevance of the FCARs. The only full-length treatment covering both traditional security over personal property and also devices that fulfil a similar economic function, such as retention of title and sales of receivables, The Law of Security and Title-Based Financing is a frequently-cited and indispensable reference work both for practitioners and academics.
He argues that the concept of family resemblances, as that concept has been refined and extended in prototype theory in the contemporary cognitive sciences, is the most plausible analytical strategy for resolving the central problem of the book. In the solution proposed, religion is conceptualized as an affair of "more or less" rather than a matter of "yes or no," and no sharp line is drawn between religion and non-religion."--BOOK JACKET.
Innovations and Challenges in Grammar traces the history of common understandings of what grammar is and where it came from to demonstrate how ‘rules’ are anything but fixed and immutable. In doing so, it deconstructs the notion of ‘correctness’ to show how grammar changes over time thereby exposing the social and historical forces that mould and change usage. The questions that this book grapples with are: Can we separate grammar from the other features of the language system and get a handle on it as an independent entity? Why should there be strikingly different notions and models of grammar? Are they (in)compatible? Which one or ones fit(s) best the needs of applied linguists if we assume that applied linguists address real-world problems through the lens of language? And which one(s) could make most sense to non-specialists? If grammar is not a fixed entity but a set of usage norms in constant flux, how can we persuade other professionals and the general public that this is a positive observation rather than a threat to civilised behaviour? This book draws upon both historical and modern grammars from across the globe to provide a multi-layered picture of world grammar. It will be useful to teachers and researchers of English as a first and second language, though the inclusion of examples from and occasional references to other languages (French, Spanish, Malay, Swedish, Russian, Welsh, Burmese, Japanese) is intended to broaden the appeal to teachers and researchers of other languages. It will be of use to final-year undergraduate, postgraduate and doctoral students as well as secondary and tertiary level teachers and researchers in applied linguistics, second language acquisition and grammar pedagogy.
“Follow the science.” How often have you picked up an education book to read how, according to the authors, the system is broken, failing, and flailing—but their ideas for fixing it will bring about a miraculous transformation? That’s not the approach of this volume. Sure, the editors believe that our system of education could achieve significantly better results. But they also recognize that schools have gotten better over time. One explanation is the progress schools have made in “following the science”. Especially in early reading and math instruction, scholars know more now about what works than we did in the past, and more schools are putting that knowledge into practice. Now, in the wake of a horrific pandemic, even the best elementary schools are struggling to help their students get their momentum back again. In this book, the editors share high-quality syntheses of evidence and insights from leading educators, academics, and other experts. And they communicate those findings in user-friendly language, with an understanding of the real-world complexities of schools and classrooms.
Martinez defines intelligence from a cognitive perspective as a repertoire of those skills, strategies, and knowledge structures that are most instrumental in human effectiveness. He posits that in today's complex, fast-paced, technologically dense, and information-rich society, intelligence is the supreme human resource. The current social context not only demands intelligence, but rewards it economically, psychically, and in other ways. His central argument in this book is this: The intellectual abilities that are crucial to modern life, including economic viability and effectiveness in daily living, correspond to the cognitive functions that are reasonably called intelligence; these intellectual abilities are learnable; we now know enough about the structure and mechanisms of intelligent thought and behavior to teach them directly. Martinez explicates his argument and provides research-based evidence to support his claim.
Wallach’s Interpretation of Diagnostic Tests, now in its Ninth Edition, has been completely revised and updated by a new author team from the Department of Hospital Laboratories, UMass Memorial Medical Center faculty, who are carrying on the tradition of Jacques Wallach’s teachings. This text serves as a practical guide to the use of laboratory tests which aids physicians in using tests more effectively and efficiently by offering test outcomes, possible meanings, differential diagnosis, and summaries of tests available. The book has been reorganized into 2 sections. The first section is devoted to an alphabetical listing of laboratory tests while stressing the integration of the clinical laboratory in the clinical decision making process. Test sensitivity, specificity, and positive and negative infectious disease probabilities are included whenever appropriate. Microbiology tests are listed in a separate chapter. The second section is devoted to disease states. Where appropriate, a patient’s chief complaint and/or physical findings are initially presented with subsequent discussions focused on discrete disease states as they relate to a patient’s chief complaint. Current molecular diagnostic testing, cytogenetics, common pitfalls, test limitations, and identification of appropriate tests for specific clinical presentations are also addressed. Ninth Edition highlights include: Detailed listing and description of routine and esoteric tests listed alphabetically, with information on when to order and how to interpret the test results based on evidence-based laboratory medicine. Information on how to work up patients with specific symptoms and the appropriate lab tests to order Up-to-date test procedures including molecular diagnostic tests Detailed microbiology chapter of infectious diseases
This volume, representing the combined efforts of a surgeon, a pathologist, and an internist, is the first comprehensive survey of the subject in many years. Interpreting anatomic, experimental, and clinical data the authors present the subject as a single disease--venous thromboembolism--with pulmonary embolism as its most important complication. Incidence, pathogenesis, clinical manifestations, diagnosis, and management have been dealt with throughout in a way that will acquaint the student with the fundamentals of the disease, the practitioner with current laboratory progress, and the research scientist with the most compelling unsolved problems in clinical management. A significant and lucidly written study, the monograph is thoroughly referenced and illustrated and includes a bibliography at the end of each chapter.
Bioinformatics, Biocomputing and Perl presents a modern introduction to bioinformatics computing skills and practice. Structuring its presentation around four main areas of study, this book covers the skills vital to the day-to-day activities of today’s bioinformatician. Each chapter contains a series of maxims designed to highlight key points and there are exercises to supplement and cement the introduced material. Working with Perl presents an extended tutorial introduction to programming through Perl, the premier programming technology of the bioinformatics community. Even though no previous programming experience is assumed, completing the tutorial equips the reader with the ability to produce powerful custom programs with ease. Working with Data applies the programming skills acquired to processing a variety of bioinformatics data. In addition to advice on working with important data stores such as the Protein DataBank, SWISS-PROT, EMBL and the GenBank, considerable discussion is devoted to using bioinformatics data to populate relational database systems. The popular MySQL database is used in all examples. Working with the Web presents a discussion of the Web-based technologies that allow the bioinformatics researcher to publish both data and applications on the Internet. Working with Applications shifts gear from creating custom programs to using them. The tools described include Clustal-W, EMBOSS, STRIDE, BLAST and Xmgrace. An introduction to the important Bioperl Project concludes this chapter and rounds off the book.
In print for the first time in over ten years, Act and Crime provides a unified account of the theory of action presupposed by both Anglo-American criminal law and the morality that underlies it. The book defends the view that human actions are always volitionally caused bodily movements andnothing else. The theory is used to illuminate three major problems in the drafting and the interpretation of criminal codes: 1) what the voluntary act requirement both does and should require; 2) what complex descriptions of actions prohitbited by criminal codes both do and should require (inaddition to the doing of a voluntary act); and 3) when two actions are 'the same' for purposes of assessing whether multiple prosecutions and multiple punishments are warranted. The book both contributes to the development of a coherent theory of action in philosophy, and it provides bothlegislators and judgees (and the lawyers who argue to both) a grounding in three of the most basic elelments of criminal liability.
If you want to be muscular, lean, and strong as quickly as possible without steroids, good genetics, or wasting ridiculous amounts of time in the gym and money on supplements...then you want to read this book. Here's the deal: Getting into awesome shape isn't nearly as complicated as the fitness industry wants you to believe. You don't need to spend hundreds of dollars per month on the worthless supplements that steroid freaks shill in advertisements. You don't need to constantly change up your exercise routines to "confuse" your muscles. I'm pretty sure muscles lack cognitive abilities, but this approach is a good way to just confuse you instead. You don't need to burn through buckets of protein powder every month, stuffing down enough protein each day to feed a third world village. You don't need to toil away in the gym for a couple of hours per day, doing tons of sets, supersets, drop sets, giant sets, etc. (As a matter of fact, this is a great way to stunt gains and get nowhere.) You don't need to grind out hours and hours of boring cardio to shed ugly belly fat and love handles and get a shredded six-pack. (How many flabby treadmillers have you come across over the years?) You don't need to completely abstain from "cheat" foods while getting down to single-digit body fat percentages. If you plan cheat meals correctly, you can actually speed your metabolism up and accelerate fat loss. In this book you're going to learn something most guys will never know: The exact formula of exercise and eating that makes putting on 10 to 15 pounds of quality lean mass a breeze...and it only takes 8-12 weeks. This book reveals secrets like... The 6 biggest myths and mistakes of building muscle that stunt 99% of guys' muscle gains. (These BS lies are pushed by all the big magazines and even by many trainers.) How to get a lean, cut physique that you love (and that girls drool over) by spending no more than 5 percent of your time each day. The 4 laws of muscle growth that, when applied, turn your body into an anabolic, muscle-building machine. You'll be shocked at how easy it really is to get big once you know what you're doing... How to develop a lightning-fast metabolism that burns up fat quickly and leaves you feeling full of energy all day long. The carefully-selected exercises that deliver MAXIMUM results for your efforts, helping you build a big, full chest, a wide, tapered back, and bulging biceps. A no-BS guide to supplements that will save you hundreds if not THOUSANDS of dollars each year that you would've wasted on products that are nothing more than bunk science and marketing hype. How to get shredded while still indulging in the "cheat" foods that you love every week like pasta, pizza, and ice cream. And a whole lot more! The bottom line is you CAN achieve that "Hollywood hunk" body without having your life revolve around it--no long hours in the gym, no starving yourself, no grueling cardio that turns your stomach. Imagine, just 12 weeks from now, being constantly complimented on how you look and asked what the heck you're doing to make such startling gains. Imagine enjoying the added benefits of high energy levels, no aches and pains, better spirits, and knowing that you're getting healthier every day. SPECIAL BONUS FOR READERS! With this book you'll also get a free 75-page bonus report from the author called "The Year One Challenge." In this bonus report, you'll learn exactly how to train, eat, and supplement to make maximum gains in your first year of training. By applying what you learn in the book and in this report, you can make more progress in one year than most guys make in three, four, or even five (seriously!). Scroll up, click the "Buy" button now, and begin your journey to a bigger, leaner, and stronger you!
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
Quickly acquire the knowledge and skills you need to confidentlyadminister, score, and interpret behavioral assessment tests Behavioral assessment tests analyze and assess a broad range ofbehavioral problems found among children and adolescents, includinghyperactivity, impulsivity, and ADHD. To use these tests properly,professionals need an authoritative source of advice and guidanceon how to administer, score, and interpret them. Cowritten byleading experts in the behavioral assessment field and the creatorsof the BASC (Behavioral Assessment System for Children), Essentialsof Behavioral Assessment is that source. Like all the volumes in the Essentials of Psychological Assessmentseries, this book is designed to help busy mental healthprofessionals quickly acquire the knowledge and skills they need tomake optimal use of major psychological assessment instruments.Each concise chapter features numerous callout boxes highlightingkey concepts, bulleted points, and extensive illustrative material,as well as test questions that help you gauge and reinforce yourgrasp of the information covered. Essentials of Behavioral Assessment is the first book to providestate-of-the-art interpretive and administrative guidelines tousing the BASC, CRS-R (Conners' Rating Scales-Revised), and CBCL(Achenbach Child Behavior Checklists), the leading and most highlyrecognized behavioral assessment tests used in the field. Theauthors also offer expert assessment of the tests' merits andinclude classroom observations. Other titles in the Essentials of Psychological Assessmentseries: Essentials of WJ IIITM Tests of Achievement Assessment Essentials of WJ IIITM Cognitive Abilities Assessment Essentials of WMS?-III Assessment Essentials of Individual Achievement Assessment Essentials of Nepsy? Assessment Essentials of Cross-Battery Assessment Essentials of Cognitive Assessment with KAIT and Other KaufmanMeasures Essentials of Nonverbal Assessment Essentials of WISC-III? and WPPSI-R? Assessment
This book contains refereed papers presented at the AMS-IMS-SIAM Summer Research Conference on the Penrose Transform and Analytic Cohomology in Representation Theory held in the summer of 1992 at Mount Holyoke College. The conference brought together some of the top experts in representation theory and differential geometry. One of the issues explored at the conference was the fact that various integral transforms from representation theory, complex integral geometry, and mathematical physics appear to be instances of the same general construction, which is sometimes called the ``Penrose transform''. There is considerable scope for further research in this area, and this book would serve as an excellent introduction.
An engaging introduction to marine chemistry and the ocean's geochemical interactions with the solid earth and atmosphere, for students of oceanography.
Here’s all the guidance you need to overcome the most difficult musculoskeletal problems using orthoses and assistive devices! With new coverage of postpolio syndrome, cranial orthoses, and now incorporating the perspectives of renowned physiatrists, this is a one-stop rehabilitation resource. Tips and Pearls in every chapter and a new 2-color format make accessing information a snap. Includes Chapters on biomechanics of spine, upper limb and hand and lower limb to help you understand the factors that determine the orthoses available for these joints. Incorporates chapters on the Orthotic Prescription, Strength and Materials, and the Normal and Pathologic Gait help you understand your role in the rehabilitative process. Contains information about the specific science behind the construction of orthoses—perfect for the Certified Prosthetist/Orthotist and the interested physician. Carries the authority and approval of AAOS, the preeminent orthopaedic professional society. Uses a new 2-color format to make the book easier to use and information easier to retain. Includes Tips and Pearls boxes in every chapter so you can quickly access expert guidance. Contains new chapters on: Orthoses for Persons with Postpolio Paralysis; Orthoses for Persons with Postpolio Syndromes; and Cranial Orthoses. Incorporates evidence-based recommendations into the chapters on spinal, upper- and lower-limb orthoses to help you select the most proven approach for your patients.
The 1920s in Paris are the pivotal years in Hemingway's apprenticeship as a writer, whether he was sitting in cafes or at the feet of Gertrude Stein. These are the heady times of the Nick Adams short stories and the writing of The Sun Also Rises; also Hemingway's first marriage to Hadley Richardson, the birth of his first son, and his discovery of the bullfights at Pamplona. Book jacket.
Here Michael Taylor develops pseudodifferential operators as a tool for treating problems in linear partial differential equations, including existence, uniqueness, and estimates of smoothness, as well as other qualitative properties. Originally published in 1981. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Reinventing economic development as if small business mattered In cities and towns across the nation, economic development is at a crossroads. A growing body of evidence has proven that its current cornerstone—incentives to attract and retain large, globally mobile businesses—is a dead end. Even those programs that focus on local business, through buy-local initiatives, for example, depend on ongoing support from government or philanthropy. The entire practice of economic development has become ineffective and unaffordable and is in need of a makeover. The Local Economy Solution suggests an alternative approach in which states and cities nurture a new generation of special kinds of businesses that help local businesses grow. These cutting-edge companies, which Shuman calls “pollinator businesses,” are creating jobs and the conditions for future economic growth, and doing so in self-financing ways. Pollinator businesses are especially important to communities that are struggling to lift themselves up in a period of economic austerity, when municipal budgets are being slashed. They also promote locally owned businesses that increase local self-reliance and evince high labor and environmental standards. The book includes nearly two dozen case studies of successful pollinator businesses that are creatively facilitating business and neighborhood improvements, entrepreneurship, local purchasing, local investing, and profitable business partnerships. Examples include Main Street Genome (which provides invaluable data to improve local business performance), Supportland (which is developing a powerful loyalty card for local businesses), and Fledge (a business accelerator that finances itself through royalty payments). It also shows how the right kinds of public policy can encourage the spread of pollinator businesses at virtually no cost.
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