Each year ecotoxicological problems become increasingly complex and encompass broader spatial and temporal scales. Our practical understanding must evolve accordingly to maintain an acceptable quality of life. Fully revised and expanded to reflect new developments, the third edition of Fundamentals of Ecotoxicology provides a broad overview of the
Michael Hrobak studied hybrid integrated front end modules for high frequency measurement equipment and especially for synthetic automatic test systems. Recent developments of innovative, critical millimeter-wave components like frequency multipliers, directional couplers, filters, triple balanced mixers and power detectors are illustrated by the author separately and in combination.
Since the end of Dennard scaling in the early 2000s, improving the energy efficiency of computation has been the main concern of the research community and industry. The large energy efficiency gap between general-purpose processors and application-specific integrated circuits (ASICs) motivates the exploration of customizable architectures, where one can adapt the architecture to the workload. In this Synthesis lecture, we present an overview and introduction of the recent developments on energy-efficient customizable architectures, including customizable cores and accelerators, on-chip memory customization, and interconnect optimization. In addition to a discussion of the general techniques and classification of different approaches used in each area, we also highlight and illustrate some of the most successful design examples in each category and discuss their impact on performance and energy efficiency. We hope that this work captures the state-of-the-art research and development on customizable architectures and serves as a useful reference basis for further research, design, and implementation for large-scale deployment in future computing systems.
Find answers fast with The 5-Minute Pediatric Consult, 9th Edition—your go-to resource for the effective medical care of infants, children, and adolescents. Using the proven 5-Minute format, it provides rapid access to information on diagnosis, treatment, medications, follow-up, and associated factors for more than 530 diseases and conditions. The 5-Minute Pediatric Consult is designed to help you make quick, accurate decisions every day ... helping you save time and offer every patient the best possible care.
Plasma Engineering, Second Edition, applies the unique properties of plasmas (ionized gases) to improve processes and performance over many fields, such as materials processing, spacecraft propulsion and nanofabrication. The book considers this rapidly expanding discipline from a unified standpoint, addressing fundamentals of physics and modeling, as well as new and real-word applications in aerospace, nanotechnology and bioengineering. This updated edition covers the fundamentals of plasma physics at a level suitable for students using application examples and contains the widest variety of applications of any text on the market, spanning the areas of aerospace engineering, nanotechnology and nanobioengineering. This is highly useful for courses on plasma engineering or plasma physics in departments of Aerospace Engineering, Electrical Engineering and Physics. It is also useful as an introduction to plasma engineering and its applications for early career researchers and practicing engineers. - Features new material relevant to application, including emerging areas of plasma nanotechnology and medicine - Contains a new chapter on plasma-based control, as well as a description of RF and microwave-based plasma applications, plasma lighting, reforming and other most recent application areas - Provides a technical treatment of the fundamental and engineering principles used in plasma applications
Since the end of Dennard scaling in the early 2000s, improving the energy efficiency of computation has been the main concern of the research community and industry. The large energy efficiency gap between general-purpose processors and application-specific integrated circuits (ASICs) motivates the exploration of customizable architectures, where one can adapt the architecture to the workload. In this Synthesis lecture, we present an overview and introduction of the recent developments on energy-efficient customizable architectures, including customizable cores and accelerators, on-chip memory customization, and interconnect optimization. In addition to a discussion of the general techniques and classification of different approaches used in each area, we also highlight and illustrate some of the most successful design examples in each category and discuss their impact on performance and energy efficiency. We hope that this work captures the state-of-the-art research and development on customizable architectures and serves as a useful reference basis for further research, design, and implementation for large-scale deployment in future computing systems.
In daily medical practice, physicians often use scores, classifications and schematic diagnostic paths to make clear and comprehensive decisions. Treatment algorithms have also proven to be effective. However, it has become increasingly difficult or even impossible to have all scores, schemata and algorithms at hand, and a search on the internet can be very time consuming. Gastrix solves this problem: unlike classic gastroenterology and hepatology textbooks, it summarizes all necessary information in the form of a pocket-sized book. Gastroenterologists will thus have all relevant information easily available at all times.
The soil is a fundamental constituent of the Earth's system, maintaining a careful state of equilibrium within the biosphere. However, this natural balance is being increasingly disturbed by a variety of anthropogenic and natural processes, leading to the degradation of many soil environments. Soil Management provides a comprehensive and authoritative introduction to the many problems, challenges and potential solutions facing soil management in the twenty-first century. Covering a range of topics, including erosion, desertification, salinization, soil structure, carbon sequestration, acidification and chemical pollution, the book also develops a prognosis for the future of soil management in the face of growing populations and global warming. Written with the needs of students in mind, each chapter provides a broad overview of a problem, analyses approaches to its solution and concludes with references and suggestions for further reading. Soil Management will be of great value to environmental science and geography undergraduates taking soil management courses in their second or third year.
Vision is the sense by which we and other animals obtain most of our information about the world around us. Darwin appreciated that at first sight it seems absurd that the human eye could have evolved by natural selection. But we now know far more about vision, the many times it has independently evolved in nature, and the astonishing variety of ways to see. The human eye, with a lens forming an image on a sensitive retina, represents just one. Scallops, shrimps, and lobsters all use mirrors in different ways. Jumping spiders scan with their front-facing eyes to check whether the object in front is an insect to eat, another spider to mate with, or a predator to avoid. Mantis shrimps can even measure the polarization of light. Animal eyes are amazing structures, often involving precision optics and impressive information processing, mainly using wet protein - not the substance an engineer would choose for such tasks. In Eyes to See, Michael Land, one of the leading world experts on vision, explores the varied ways in which sight has evolved and is used in the natural world, and describes some of the ingenious experiments researchers have used to uncover its secrets. He also discusses human vision, including his experiments on how our eye movements help us to do everyday tasks, as well as skilled ones such as sight-reading music or driving. He ends by considering the fascinating problem of how the constantly shifting images from our eyes are converted in the brain into the steady and integrated conscious view of the world we experience.
In February 2016, while testifying in a House Appropriations Subcommittee hearing, U.S. Attorney General Loretta Lynch, a Barack Obama appointee, promised that her department would act with independence in investigating Hillary Clinton's usage of a personal email server during her tenure as Secretary of State. During that hearing, Congressman John Carter (R-TX) asked Lynch: If the FBI makes the case that Hillary Clinton mishandled classified information and put America's security at risk, will you prosecute the case? . . .[P]lease look the American people in the eye and tell us what your position is as you are the chief prosecutor of the United States. In response to this questioning, Lynch asserted that: [The matter] is being handled by . . . independent attorneys in the Department of Justice. They follow the evidence, they look at the law and they'll make a recommendation to me when the time is appropriate. . .This will be conducted as every other case. We will review all the facts and all the evidence and come to an independent conclusion as how to best handle it. And I am also aware of no efforts to undermine our review or investigation into this matter at all (Goldman 2016). Despite strong claims of prosecutorial independence, many Republicans complained that a Department of Justice run by Obama appointees could not impartially pass legal judgment on the Hillary Clintonemails matter. A June 27, 2016 meeting between Lynch and former U.S. President Bill Clinton would not help matters. The two privately talked for approximately 20 minutes on a plane sitting on the Phoenix Sky Harbor airport tarmac in a meeting described as unplanned and "primarily social." Despite the meeting's claimed innocuous content, it "caused a cascading political storm" for Hillary Clinton's presidential campaign and "provided fodder for Republicans who have accused the Justice Department of bias in its inquiry into Secretary Clinton's use of a private email server at the State Department" (Chozick 2016). Even Democrats expressed concerns about the meeting Senator Chris Coons (D-DE) remarked that "I do think that this meeting sends the wrong signal . . . I think she should have steered clear, even of a brief, casual social meeting with the former president"--
This unique multidisciplinary 8-volume set focuses on the emerging issues concerning synthesis, characterization, design, manufacturing and various other aspects of composite materials from renewable materials and provides a shared platform for both researcher and industry. The Handbook of Composites from Renewable Materials comprises a set of 8 individual volumes that brings an interdisciplinary perspective to accomplish a more detailed understanding of the interplay between the synthesis, structure, characterization, processing, applications and performance of these advanced materials. The Handbook comprises 169 chapters from world renowned experts covering a multitude of natural polymers/ reinforcement/ fillers and biodegradable materials. Volume 5 is solely focused on 'Biodegradable Materials'. Some of the important topics include but not limited to: Rice husk and its composites; biodegradable composites based on thermoplastic starch and talc nanoparticles; recent progress in biocomposites of biodegradable polymer; microbial polyesters: production and market; biodegradable and bioabsorbable materials for osteosynthesis applications; biodegradable polymers in tissue engineering; composites based on hydroxyapatite and biodegradable polylactide; biodegradable composites; development of membranes from biobased materials and their applications; green biodegradable composites based on natural fibers; fully biodegradable all-cellulose composites; natural fiber composites with bioderivative and/or degradable polymers; synthetic biodegradable polymers for bone tissue engineering; polysaccharides as green biodegradable platforms for building up electroactive composite materials; biodegradable polymer blends and composites from seaweeds; biocomposites scaffolds derived from renewable resources for bone tissue repair; pectin-based composites; recent advances in conductive composites based on biodegradable polymers for regenerative medicine applications; biosynthesis of PHAs and their biomedical applications; biodegradable soy protein isolate/poly(vinyl alcohol) packaging films; and biodegradability of biobased polymeric materials in natural environment.
Given the unprecedented demands on the U.S. military since 2001 and the risks posed by stress and trauma, there has been growing concern about the prevalence and consequences of sleep problems. This first-ever comprehensive review of military sleep-related policies and programs, evidence-based interventions, and barriers to achieving healthy sleep offers a detailed set of actionable recommendations for improving sleep across the force.
Self-Doped Conducting Polymers provides an introduction to conducting polymers in general and self-doped conducting polymers in particular. This is followed by an in depth exploration of the synthesis, properties and utilization of several types of self-doped polymers. Optimization of self-doped polymers is also discussed.
The thoroughly updated Second Edition of Health Promotion in Multicultural Populations grounds readers in the understanding that health promotion programs in multicultural settings require an in-depth knowledge of the cultural group being targeted. Numerous advances and improvements in theory and practice in health promotion and disease prevention (HPDP) are presented. Editors Michael V Kline and Robert M Huff have expanded the book to include increased attention directed to students and instructors while also continuing to provide a handbook for practitioners in the field. This book combines the necessary pedagogical features of a textbook with the scholarship found in a traditional handbook. Several new chapters have been added early in the text to provide stronger foundations for understanding the five sections that follow. The book considers five specific multicultural groups: Hispanic/Latino, African American, American Indian and Alaska Native, Asian American, and Pacific Islander populations. The first chapter in each of the five population group sections presents an overview devoted to understanding this special population from a variety of perspectives. The second chapter of each section explains how to assess, plan, implement, and evaluate health promotion programs for each of the specific groups. The third chapter in each section highlights a case study to emphasize points made in the overview and planning chapters. The fourth chapter in each section provides "Tips" for working with the cultural groups described in that section. New to the Second Edition Devotes a chapter to traditional health beliefs and traditions that can help the practitioner better understand how these beliefs and traditions can impact on Western biomedical practices Contains a new chapter that evaluates health disparities across the U.S. Presents a new chapter that examines ethical dilemmas and considerations in a multicultural context Offers updated citations and content throughout Gives selected Web sites of interest Intended Audience This book is ideal for practitioners and students in the fields of health promotion and education, public health, nursing, medicine, psychology, sociology, social work, physical therapy, radiology technology and other allied professions.
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Make the most effective diagnostic and therapeutic decisions quickly and efficiently! Find answers fast with The 5-Minute Pediatric Consult, 8th Edition – your go-to resource for the effective medical care of infants, children, and adolescents. Using the proven 5-Minute format, it provides rapid access to information on diagnosis, treatment, medications, follow-up, and associated factors for more than 500 diseases and conditions. The 5-Minute Pediatric Consult is designed to help you make quick, accurate decisions every day ... helping you save time and offer every patient the best possible care. Written by experts in the field of pediatrics and associated subspecialties and published by the leader in medical content, The 5-Minute Pediatric Consult, 8th Edition includes a 10-Day Free Trial to 5MinuteConsult.com.
Consistently lauded for its comprehensiveness and full-color color presentation, the latest edition of Rheumatology by Marc C. Hochberg, MD, MPH et al. continues the tradition of excellence of previous editions. Designed to meet the needs of the practicing clinician, it provides extensive, authoritative coverage of rheumatic disease from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format covering all major disorders of the musculoskeletal system in complete, self-contained chapters. Get trusted perspectives and insights from chapters co-authored by internationally renowned leaders in the field, 25% of whom are new to this edition. Track disease progression and treat patients more effectively with the most current information, including 22 new chapters on genetic findings, imaging outcomes, and cell and biologic therapies as well as rheumatoid arthritis and SLE. Incorporate the latest findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics.
In the never-ending quest for miniaturization, optically controlled particle trapping has opened up new possibilities for handling microscopic matter non-invasively. This thesis presents the application of photorefractive crystals as active substrate materials for optoelectronic tweezers. In these tweezers, flexible optical patterns are transformed into electrical forces by a photoconductive material, making it possible to handle matter with very high forces and high throughput. Potential substrate materials’ properties are investigated and ways to tune their figures-of-merit are demonstrated. A large part of the thesis is devoted to potential applications in the field of optofluidics, where photorefractive optoelectronic tweezers are used to trap, sort and guide droplets or particles in microfluidic channels, or to shape liquid polymers into optical elements prior to their solidification. Furthermore, a new surface discharge model is employed to discuss the experimental conditions needed for photorefractive optoelectronic tweezers.
What happened to the so-called "golden age" of the postwar boom? Unprecedented rates of economic growth, profitability, and wage increases during the 1950s and 60s have given way to a global capitalist economy in disarray. Reassessing common interpretations of postwar economic history and geography, this book focuses on the evolution of the global economy from the 1950s to the present. Based on extensive research, the book assesses histories of growth, profitability, and technological change in core industrial economies (Japan and the USA), raw material dependent economies (Australia and Canada), and several newly industrializing countries (Brazil, South Korea, and Taiwan). The authors build on standard models of economic change to incorporate new developments in regional dynamics: they use nonlinear, nonequilibrium, and evolutionary arguments to frame discussions of profit rates, technological change, and interregional capital flows.
Professor Blakeney has written a detailed work on the current state of international enforcement of intellectual property rights. Using the background to, and the negotiation of, the Anti-Counterfeiting Trade Agreement, as well as the provisions of the ACTA itself, the book is a mine of information and analysis. Professor Blakeney's long experience of work on the laws and practice of IPR enforcement as a right-holder, an administrator, and as an academic and researcher, are second to none and it shows in this all-encompassing work.' – John Anderson, Global Anti-Counterfeiting Network This important book is the first detailed analytical treatment of the Anti-Counterfeiting Trade Agreement (ACTA) and its impact on intellectual property enforcement. The ACTA had been formulated to deal with the burgeoning growth in the trade in counterfeit and pirate products which was estimated to have increased ten-fold since the promulgation of the TRIPS Agreement in 1994. The book clarifies how the ACTA supplements the enforcement provisions of the TRIPS Agreement, namely by: expanding the reach of border protection to infringing goods in transit; providing greater detail of the implementation of civil enforcement and; providing for the confiscation of the proceeds of intellectual property crimes. As the book illustrates, a significant additional innovation is the introduction of provisions dealing with enforcement of intellectual property rights in the digital environment. This book will strongly appeal to intellectual property rights policymakers at the World Trade Organization and World Intellectual Property Organization, legal practitioners, academics and students.
This guide to the Eastern Orthodox churches of the world is presented in alphabetical order by their chief sees or national boundaries. Each entry includes a brief summary of the church's history; the location, number, and language of its members; the official title of the primate; the language used in the church; primary sources for the entry; and a chronology of the reigns of the church's primates from its founding to the present day. A concise preface explains the criteria used to include churches in the book and the process by which the entries were created. Descriptions of more than 75 churches make up the bulk of the volume. Following the individual entries are tables presenting comparative names of the primates (rendered in transcriptions of their original languages); statistical information about the primates (most common names, longest reigns); and current hierarchs as of 2004, arranged by church, date of accession, and date of birth. A glossary, selected bibliography and general index complete the work.
This SpringerBrief offers a state of the art analysis of electronic word-of-mouth (eWOM) communications and its role in marketing. The book begins with an overview of traditional word-of-mouth (WOM) and its evolution to eWOM. It discusses the differences between traditional and online WOM. The book examines why people engage in eWOM communications, but also how consumers evaluate its persuasiveness. It also looks at the effects of eWOM. The book identifies current gaps in the eWOM research, but also highlights future directions for this growing field. eWOM is an important marketing technique in brand communications, and it plays an important role in modern e-commerce. Marketers become extremely interested in enhancing the power of eWOM developing loyalty programs and building brands. Studying the effect of eWOM can be beneficial for companies. This book should be a good resource for scholars and practitioners that need to understand the pervasive effects of eWOM.
Healthcare professionals, including doctors, pharmacists and nurses, are often confronted with patients who use over-the-counter (OTC) herbal medicinal products and food supplements. While taking responsibility for one’s own health and treatment options is encouraged, many patients use these products based on limited (and sometimes inaccurate) information from non-scientific sources, such as the popular press and internet. There is a clear need to offer balanced, well-informed advice to patients, yet a number of studies have shown that, generally, conventionally trained health practitioners consider their knowledge about herbal medicinal products and supplements to be weak. Phytopharmacy fills this knowledge gap, and is intended for use by the busy pharmacist, nurse, or doctor, as well as the ‘expert patient’ and students of pharmacy and herbal medicine. It presents clear, practical and concise monographs on over a hundred popular herbal medicines and plant-based food supplements. Information provided in each monograph includes: • Indications • Summary and appraisal of clinical and pre-clinical evidence • Potential interactions • Contraindications • Possible adverse effects An overview of the current regulatory framework is also outlined, notably the EU Traditional Herbal Medicinal Products Directive. This stipulates that only licensed products or registered traditional herbal medicinal products (THRs), which have assured quality and safety, can now legally be sold OTC. Monographs are included of most of the major herbal ingredients found in THRs, and also some plant-based food supplements, which while not strictly medicines, may also have the potential to exert a physiological effect.
Taiwan's electronics industry, especially the semiconductor and information products sectors, is characterized by rapid growth and high potential. This book investigates the past performance, current status, and future development of this industry, providing engineers with important data. Corporate business planners and electronics managers will find helpful information for decision making regarding joint ventures and alliances with Taiwanese manufacturers.
Encapsulation Technologies for Electronic Applications, Second Edition, offers an updated, comprehensive discussion of encapsulants in electronic applications, with a primary emphasis on the encapsulation of microelectronic devices and connectors and transformers. It includes sections on 2-D and 3-D packaging and encapsulation, encapsulation materials, including environmentally friendly 'green' encapsulants, and the properties and characterization of encapsulants. Furthermore, this book provides an extensive discussion on the defects and failures related to encapsulation, how to analyze such defects and failures, and how to apply quality assurance and qualification processes for encapsulated packages. In addition, users will find information on the trends and challenges of encapsulation and microelectronic packages, including the application of nanotechnology. Increasing functionality of semiconductor devices and higher end used expectations in the last 5 to 10 years has driven development in packaging and interconnected technologies. The demands for higher miniaturization, higher integration of functions, higher clock rates and data, and higher reliability influence almost all materials used for advanced electronics packaging, hence this book provides a timely release on the topic. - Provides guidance on the selection and use of encapsulants in the electronics industry, with a particular focus on microelectronics - Includes coverage of environmentally friendly 'green encapsulants' - Presents coverage of faults and defects, and how to analyze and avoid them
This book serves as a one-stop source for comprehensive information on the entertainment industry, providing a historical overview of the economics of the field, a series of short biographies of the impact makers, and an extensive annotated bibliography of more sources for in-depth research. Entertainment Industry: A Reference Handbook casts the spotlight on the evolution of the entertainment industry over the entire span of the 20th century, covering everything from vaudeville to radio and from sports to television and movies. It explores how the entertainment industry stands apart from other high-dollar, big-business enterprises with regard to how its economy is sustained, and it serves as a handy source for more in-depth information that general readers will find fascinating. An extensive annotated bibliography guides reader through their research, while a historical overview of the economics of the industry, a series of short biographies of the impact makers in the industry, and sources of more current information makes this work essential reading for anyone seeking comprehensive and specific information about the entertainment industry.
Mathog’s Atlas of Craniofacial Trauma covers a practical step-by-step approach of procedures to treat craniofacial fractures. This definitive book on surgery for craniofacial trauma covers a wide range of procedures that cross a number of specialties. Each procedure has been updated to reflect current methods being utilized today. Although the focus is on the facial skeleton, there are adequate presentations to orient the reader to vascular, central nervous system, dental, and ophthalmic injuries, which is important as most of these injuries cross specialties. This completely revised Second Edition will have multiple new chapters, including Imaging of Craniofacial Fractures; Plates, Materials, and Instrumentation; Multidisciplinary Approach to Trauma; Free Flap Reconstruction of the Mandible.
The fundamental purpose of this book is to synthesise the divergent literature on aquatic lipids into a co-ordinated, digestible form. A large part of the book addresses lipid composition and production in freshwater organisms, with chapters on phytoplankton, zooplankton and benthic invertebrates. A common theme throughout the book is the function of lipids in aquatic food webs, with a chapter devoted exclusively to lipids as indicators of health in fish populations. A complementary chapter highlights the role of lipids and essential fatty acids in mariculture. Methodologies to determine the lipid content of aquatic samples and suggestions as to the utility of fatty acids as trophic markers are included, as is one chapter on the role of lipids in the bioaccumulation and bioconcentration of toxicants and another on the relationships between lipids and surface films and foams. The final chapter highlights the similarities and differences between lipids of marine and freshwater origin. Students and researchers in ecology, phycology, aquatic toxicology, physiological ecology and limnology will find this an invaluable guide and reference.
An explanation of the concepts and principles of marketing as they are increasingly being applied in the travel and tourism industry. Numerous examples are used throughout the text, which are drawn from recent practice in several countries.
Revised, updated, and enhanced from cover to cover, the Sixth Edition of Greenfield’s Surgery: Scientific Principles and Practice remains the gold standard text in the field of surgery. It reflects surgery’s rapid changes, new technologies, and innovative techniques, integrating new scientific knowledge with evolving changes in surgical care. Updates to this edition include new editors and contributors, and a greatly enhanced visual presentation. Balancing scientific advances with clinical practice, Greenfield’s Surgery is an invaluable resource for today’s residents and practicing surgeons.
In this thoroughly revised and updated third edition, Michael Blakeney investigates the European laws which regulate the use of geographical indications (GIs) in the marketing of agricultural products, food, wines and spirits, and cultural products such as handicrafts. Key updates include new material exploring the 2023 Regulation on GIs for craft and industrial products, and the protection of wine GIs under the Common Organisation of Agricultural Markets (CMO).
In Ecotoxicology: A Hierarchical Treatment, 20 recognized experts from around the world identify and present the fundamental concepts of ecotoxicology at the biological level central to their own research. Superbly organized, the book proceeds sequentially by chapter from the chemical to cellular to the ecosystem level, making it easy to read, understand, and use. Specifically, each author identifies important hypotheses, paradigms, "false" paradigms, or new techniques in his or her research area. As a result, this book is a stimulating progressive treatment of ecotoxicology at all levels of organization. Each chapter draws mechanistic interpretation from the next lower level and attempts to predict effects at the next higher level. This innovative approach underscores ecotoxicology's potential for development into a new discipline and makes Ecotoxicology: A Hierarchical Treatment the definitive reference at this crucial juncture.
In this book Michael Riccards, renowned scholar of the American presidency, focuses his study on the vagaries of presidential leadership between nations. Tracing the history of the often difficult and contentious diplomatic relations between the United States and China, Riccards describes and analyzes various meetings and interactions. He concludes that war and trade necessities intimately bound the histories of both nations--often in spite of their individual rhetoric and initiatives. Students and scholars whose focus is the points of contact between U.S. and Asian history will find this book essential reading.
Chromic or colour related phenomena are produced in response to a chemical or physical stimulus. This new edition will update the information on all those areas where chemicals or materials interact with light to produce colour, a colour change, or luminescence especially in the imaging, analysis, lighting and display areas. The book has been restructured to show greater emphasis on applications where 'coloured' compounds are used to transfer energy or manipulate light in some way therefore reducing the details on classical dyes and pigments. In the past eight years, since the previous edition, there has been a remarkable increase in the number of papers and reviews being produced reflecting the growth of interest in this area. This ongoing research interest is matched by a large number of new technological applications gaining commercial value covering e.g. biomedical areas, energy, data storage, physical colour, bio-inspired materials and photonics. This book appeals to industrial chemists, professionals, postgraduates and as high level recommended reading for colour technology courses.
This Synthesis Lecture focuses on techniques for efficient data orchestration within DNN accelerators. The End of Moore's Law, coupled with the increasing growth in deep learning and other AI applications has led to the emergence of custom Deep Neural Network (DNN) accelerators for energy-efficient inference on edge devices. Modern DNNs have millions of hyper parameters and involve billions of computations; this necessitates extensive data movement from memory to on-chip processing engines. It is well known that the cost of data movement today surpasses the cost of the actual computation; therefore, DNN accelerators require careful orchestration of data across on-chip compute, network, and memory elements to minimize the number of accesses to external DRAM. The book covers DNN dataflows, data reuse, buffer hierarchies, networks-on-chip, and automated design-space exploration. It concludes with data orchestration challenges with compressed and sparse DNNs and future trends. The target audience is students, engineers, and researchers interested in designing high-performance and low-energy accelerators for DNN inference.
Historically, the major emphasis on the study of purinergic systems has been predominantly in the areas of physiology and gross pharmacology. The last decade has seen an exponential in crease in the number of publications related to the role of both adenosine and A TP in mammalian tissue function, a level of interest that has evolved from a more molecular focus on the identity of adenosine and A TP receptor subtypes and the search for selective ligands and development of radioligand binding assays by Fred Bruns and colleagues (especially that for A receptors) that played z a highly significant role in advancing research in the area. In the 60 years since adenosine was first shown to be a potent hypotensive agent, a considerable investment has been made by several pharmaceutical companies-including Abbott, Byk Gulden, Takeda, Warner-LambertlParke Davis, Boehringer Mann heim, Boehringer Ingelheim, Nelson/Whitby Research and CffiA Geigy-as well as John Daly's laboratory at the National Institutes of Health, to design new adenosine receptor ligands, and both agon ists and antagonists with the aim of developing new therapeutic entiities. Numerous research tools have derived from these efforts including: 2-chloroadenosine, R-PIA (~-phenylisopropyladeno sine; NECA (5' N-ethylcarboxamidoadenosine); CV1808; CI936; PD 125,944; ~-benzyladenosine; PACPX; CPX; CPT; XAC; CGS 15943 and CGS 21680. Yet in the realm of therapeutics it was only in 1989 that adenosine itself was approved for human use in the treatment of supraventricular arrythmias.
This book examines the interactions between implants and biological fluids that cause fouling in biosensors and the serious issue of thrombus formation suitable for professional researchers in academia and industry and postgraduate students.
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