From the command line to Apple's graphical tools, this book uses a thorough, fundamental approach that leads readers to mastery of every aspect of the server. Full of much-needed insight, clear explanations, troubleshooting tips, and security information in every chapter, the book shows system administrators how to utilize the software's capabilities and features for their individual needs. Some of the topics covered in detail include: Installation Deployment Server management Directory services Web application services System interaction Data gathering Stress planning This comprehensive guide also takes the time to carefully highlight and analyze the differences between Mac OS X and the other server platforms.Whether you're a seasoned Unix or Windows administrator or a long-time Mac professional, Essential Mac OS X Panther Server Administration provides you with the depth you're seeking to maximize the potential of your Mac OS X Panther Server.
The Merger: M.D.s and D.O.s in California If you are interested in the recent history of the medical professions, this book is for you. If personal narratives of historical events speak to you as a second layer of documentation, this book is for you. If you are aware that in America there exist two separate yet equal, fully licensed physicians, M.D.s and D.O.s, you might be interested in learning about their unique relationship in California. If you know little about D.O.s, this book will give you a picture of their approach to patient care and to their M.D. colleagues. The osteopathic profession in California has a unique history, as it differs dramatically from the professions history in the rest of the nation. More than 100 years ago, a small pioneering group of osteopathic physicians established in Southern California the Pacific School of Osteopathy to graduate physicians and surgeons with the ability to acquire an unlimited license. Since then, the educational, research, and regulatory arenas of osteopathy have seen in California low points of near elimination and high points of recognition. Cultures are based on firm beliefs in the truth of their understanding of the world. Often they collide with those who respect different truths. Similarly, the medical culture in California went through collisions between osteopathic and allopathic medicine, often in response to competition and antagonism. Which values and beliefs about each others profession were held so fervently in California that prompted the unique event of absorbing the osteopathic profession into allopathic mainstream medicine? This project explores the events, unique to California but with repercussions nation-wide, of a merger between osteopathic and allopathic medicine. In 1962, the relatively small medical organization of fully licensed osteopathic physicians (the California Osteopathic Organization) merged with the much larger mainstream medical profession (the California Medical Association). What were the incentives for a fully licensed parallel healthcare profession to forfeit its identity and philosophy? What key players and leaders emerged? How did the individual practicing physician think and feel about the merger? While about two thousand osteopathic physicians changed to the M.D. degree, about two hundred California D.O.s did not merge but persevered in their battle to restore the licensing power of their profession in California. What social and personal motivational sources sustained this group for over a decade? How has osteopathys unique history affected medical education and professional relations, nation-wide and internationally? Answers to these questions have emerged in historical narratives by key persons figuring in the events. Most of them have not written about their lives and their social and political surroundings at the time of the merger and its repercussions. Many never learned the long-term outcomes of their endeavors. Our multidisciplinary research team transcribed in-depth interviews to capture the thoughts and feelings among individuals who played significant roles from the 1940s to the 70s. With the approval of the Institutional Review Board of the University of California, Irvine for the protection of the participants rights, we asked a diverse group, 35 in all, of physicians, administrators, lawyers and lobbyists, to provide their historical narratives and their suggestions for future directions. Our objective has been to give an unbiased account, listening equally to representatives of allopathy, osteopathy, and politics. Inspired by Dr. Gevitz cogent academic analysis of osteopathic medicine in America, this book presents personal perceptions of events, integrated with documented descriptions, stored in archives, to facilitate the readers understanding and analysis. The work has been based on the assumption
MicroRNAs (miRNAs) are a member of the family of non-coding RNA molecules, and consist of small conserved sequences between 19–25 nucleotides in length that are responsible for regulating many cellular functions by affecting a wide range of messenger RNAs in a sequence specific manner. Fundamental biological processes like cell proliferation and growth, stress resistance, tumorigenesis, fat metabolism, and neural development have all been shown to be governed by miRNAs. miRNAs carry out the post-transcriptional silencing of gene expression via targeting the 30-untranslated region (UTR) of the complementary mRNA sequence. The dysregulation of the expression levels of various miRNAs is typical of tumor cells, and has been associated with tumor progression and poor prognosis. Many miRNAs are up-regulated in cancer, where they can silence tumor suppressor genes such as apoptosis and immune response associated genes. Therefore, it is possible to profile the expression levels of miRNAs as biomarkers, in order to diagnose cancer and noncancerous diseases. Moreover, cancer detection in the early stages is crucial in clinical situations. Characterization of miRNAs in serum, plasma, and other bodily fluids, and understanding their stability against RNase degradation, is important to assess their suitability as biomarkers and diagnostic tools. Exosomes play an important role in inter-cellular communications, and these nanosized particles have various functions in diverse physiological pathways, in normal as well as abnormal cells. Exosomes can carry diverse cargos such as mRNAs, miRNAs, and proteins that transfer information between donor and recipient cells. Furthermore, uptake of exosomes and their cargos may promote or suppress various molecular and cellular pathways, which alter the cellular behavior. Many reports have discussed the role of exosomes released from cancer cells on the progression of cancer at various stages. Exosomes and their cargos may affect the growth of the tumor, metastasis, drug resistance, immune system function, as well as angiogenesis. Therefore, exosomes have been explored as diagnostic biomarkers in many cancers. Moreover, exosomes can be used as biological vehicles to deliver different drugs and agents like doxorubicin (DOX), miRNAs, and siRNAs. The present book covers the role of exosomes and micro-RNAs in the pathogenesis and treatment of various diseases.
On September 10, 1897, in the hamlet of Lattimer mines, Pennsylvania, an armed posse took aim and fired into a crowd of oncoming mine workers, who were marching in their corner of the coal-mining region to call their fellow miners out on strike. The marchers Poles, Slovaks, Hungarians, most of whom could not yet speak English were themselves armed only with an American flag and a timid, budding confidence in their new found rights as free men in their newly adopted country. The mine operators took another view of these rights and of the strange, alien men who claimed them. When the posse was done firing, nineteen of the demonstrators were dead and thirty-nine were seriously wounded. Some six months later a jury of their peers was to exonerate the deputies of any wrong-doing. This long-forgotten incident is here movingly retold by Michael Novak, himself the son of Slovak immigrants and one of our most gifted writers and social observers. In his hands, the so-called "Lattimer Massacre" becomes not only a powerful story in its own right (and an invaluable key to the history of the growth of the united mine Workers), but an allegory of that peculiarly American experience undergone over and over again throughout the land, and down to this very day; the experience of new immigrants, still miserable with poverty and bewilderment and suffering the trauma of culture shock, being confronted by the hostility and blind contempt of the "real" Americans. In Michael Novak's uniquely vivid account, the incident at Lattimer is seen as a tragedy brought on not so much by inhumanity as by the profound failure of majority WASP society to understand the needs and responses of "foreigners." The Guns of Lattimer is a gripping book that tells Americans, old and new, a great deal about themselves and the society they live in.
Part of the highly regarded Master Techniques in Orthopaedic Surgery series, Fractures, Fourth Edition, is a concise, lavishly illustrated reference covering the most advanced, successful surgical techniques for fractures of the upper extremity, lower extremity, pelvis, and acetabulum—all in step-by-step detail. This fully revised edition presents the preferred techniques of surgical masters, illustrated with full-color, sequential, surgeon’s-eye view intraoperative photographs, as well as superb drawings by noted medical illustrators. New and rewritten chapters keep you fully up to date with recent changes in the field.
In order for a community to be truly prepared to respond to any type of emergency, it must develop effective emergency planning. Emergency Planning guides readers through the steps of developing these plans, offering a number of strategies that will help ensure success. It delves into the patterns of human disaster behavior, social psychology, and communication as well as the basics of generic protective actions, planning concepts, implementation, and action.
The recent devastation caused by tsunamis, hurricanes and wildfires highlights the need for highly trained professionals who can develop effective strategies in response to these disasters. This invaluable resource arms readers with the tools to address all phases of emergency management. It covers everything from the social and environmental processes that generate hazards to vulnerability analysis, hazard mitigation, emergency response, and disaster recovery.
Significantly revised and updated, the new edition of this highly regarded reference on the shoulder continues to impress. A multitude of leading international authorities—30% new to this 4th edition—present today’s most comprehensive, in-depth view of the current state of shoulder practice, all in a beautifully illustrated, full-color 2-volume masterwork. They deliver the most up-to-date coverage of shoulder function and dysfunction, along with practical approaches for patient evaluation and balanced discussions of treatment alternatives—open and arthroscopic, surgical and nonsurgical. Greatly expanded and visually enhanced coverage of arthroscopy, as well as many new chapters, provide expert guidance on the latest minimally invasive approaches. New “Critical Points summary boxes highlight key technical tips and pearls, and two DVDs deliver new videos that demonstrate how to perform open and arthroscopic procedures. And now, as an Expert Consult title, this thoroughly updated 4th edition comes with access to the complete fully searchable contents online, as well as videos of arthroscopic procedures from the DVDs—enabling you to consult it rapidly from any computer with an Internet connection. Includes tips and pearls from leaders in the field, as well as their proven and preferred methods. Offers scientifically based coverage of shoulder function and dysfunction to aid in the decision-making process. Provides a balance between open and arthroscopic techniques so you can chose the right procedures for each patient. Includes the entire contents of the book online, fully searchable, as well as procedural videos from the DVDs, for quick, easy anywhere access. Features 30% new expert contributors and new chapters, including Effectiveness Evaluation and the Shoulder, Revision of Rotator Cuff Problems, Management of Complications of Rotator Cuff Surgery, Management of Infected Shoulder Prosthesis, and others, providing you with abundant fresh insights and new approaches. Provides new and expanded material on the management of advanced arthritis and CTA, infected arthroplasty, procedures to manage the stiff shoulder, and much more keeping you on the cusp of the newest techniques. Offers enhanced coverage of shoulder arthroscopy, including basic and advanced techniques and complications, for expert advice on all of the latest minimally invasive approaches. Devotes an entire new chapter to research frontiers to keep you apprised of what’s on the horizon. Incorporates “Critical Points summary boxes that highlight key technical tips and pearls. Uses a new full-color design for optimal visual guidance of arthroscopic views and procedures. Presents new videos on arthroscopic procedures on 2 DVDs to help you master the latest techniques.
From award-winning chef Gabriel Kreuther, the definitive cookbook on rustic French cooking from Alsace Gabriel Kreuther is the cookbook fans of the James Beard Award-winning chef have long been waiting for. From one of the most respected chefs in the United States, this cookbook showcases the recipes inspired by Kreuther’s French-Swiss-German training and refined global style, one that embraces the spirits of both Alsace, his homeland, and of New York City, his adopted home. Sharing his restaurant creations and interpretations of traditional Alsatian dishes, Kreuther will teach the proper techniques for making every dish, whether simple or complex, a success. Recipes include everything from the chef's take on classic Alsatian food like the delicious Flammekueche (or Tarte Flambée) and hearty Baeckeoffe (a type of casserole stew) to modern dishes like the flavorful Roasted Button Mushroom Soup served with Toasted Chorizo Raviolis and the decadent Salmon Roe Beggar’s Purse garnished with Gold Leaf. Featuring personal stories from the chef's childhood in France and career in New York as well as stunning photography, Gabriel Kreuther is the definitive resource for Alsatian cooking worthy of fine dining.
Michael H. Weisman, Michael Weinblatt, James S Louie, and Ronald Van Vollenhoven offer their unique insights into choosing the correct pharmacological and non-pharmacological therapies for your patients. Chapters cover the full breadth of rheumatic diseases, rheumatoid arthritis, lupus, connective tissue diseases, osteoporosis, regional pain disorders, and fibromyalgia. The full-color design presents detailed clinical photographs and treatment algorithms for visual guidance and easy reference. Covers the treatment of pediatric patients as well as adults so that you can properly address the particular needs of any patient you see. Features the guidance and specific recommendations of experts from United States and Europe for a state-of-the-art approach to the variety of treatments currently in use. Displays the clinical manifestations of rheumatic diseases in full color, along with treatment algorithms for easy at-a-glance reference.
Biotechnology represents a major area of research focus, and many universities are developing academic programs in the field. This guide to biomanufacturing contains carefully selected articles from Wiley's Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology as well as new articles (80 in all,) and features the same breadth and quality of coverage and clarity of presentation found in the original. For instructors, advanced students, and those involved in regulatory compliance, this two-volume desk reference offers an accessible and comprehensive resource.
Fully updated with completely updated content, exciting new authors, and commentary by national and international experts in the field, Rockwood and Matsen’s The Shoulder, 5th Edition continues its tradition of excellence as the cornerstone reference for effective management of shoulder disorders. This masterwork provides how-to guidance on the full range of both tried-and-true and recent surgical techniques, including both current arthroscopic methods and the latest approaches in arthroplasty. An outstanding editorial team headed by Drs. Charles A. Rockwood, Jr. and Frederick A. Matsen III ensures that you have the tools you need to achieve optimal patient outcomes for any shoulder challenge you encounter. Throughout the book the authors focus on the value of the procedures to patients, showing ways that expense and risk can be minimized. Combines the ‘how to’ for ‘tried and true’ shoulder procedures along with the latest arthroscopic methods for managing shoulder disorders. Focuses on the most challenging open procedures, including those often overlooked in training programs, yet thoroughly reviews the rationale for using minimally invasive arthroscopic techniques whenever possible. Offers scientifically based coverage of shoulder function and dysfunction to aid in the decision-making process. Features new commentaries from international authorities – including dissenting and alternative viewpoints -- and final comments by our editorial experts. Covers new approaches, including reverse total shoulder, the latest rotator cuff repair methods, and the "ream and run" procedure, as well as emerging imaging methods.
Blending the latest technical and clinical skills of hand surgery and hand therapy, Hand and Upper Extremity Rehabilitation: A Practical Guide, 4th Edition walks you through the treatment of common medical conditions affecting the upper extremities and highlights non-surgical and surgical procedures for these conditions. This expanded fourth edition presents the latest research in hand and upper extremity rehabilitation and provides the purpose and rationale for treatment options. Clinical outcomes included in each chapter relate clinical expectations to the results of clinical research trials, providing you with the expected range of motion and function based on evidence in the literature. Highly structured organization makes information easy to find, allowing the text to function as a quick reference in the clinical setting. Contributors from a variety of clinical settings like hand therapy clinics, hospitals, and outpatient clinics means you get to learn from the experience of clinicians working in diverse clinical contexts like yourself. Over 400 line drawings and clinical photographs delineate important concepts described in text. Chapters divided into eight parts - Wound Management, Nerve Injuries, Tendon Injuries, Shoulder, Elbow, Wrist and Distal Radial Ulnar Joint, Hand, and Special Topics - so information can be located quickly. 51 leading experts offer fresh insight and authoritative guidance on therapeutic approaches for many common diagnoses. Treatment guidelines presented for each stage of recovery from a wide range of upper extremity conditions. NEW! Authoritative quick reference guide to surgical and non-surgical procedures for hand and all upper extremity conditions. NEW! Updated information and references offers the latest information and research in the areas of hand and upper extremity rehabilitation. NEW! Larger trim size and new design accommodates a two-column format that is easier to follow.
Like a dating service, this edition (updated since the initial 1996 one) guides all levels of executives to the job recruiters most likely to match their industry and salary requirements. To avert perils akin to blind dating, a state-by-state recruiter directory and recruiter index by industry are provided, as well as a briefing on strategies for best utilizing both retainer and contingency-based search firms. Recruiter listings include contact information, minimum salary placed, and specialty area(s), but not fees, Internet presence, or any evaluative data on their placement record; nor is the overall success of such corporate "headhunters" addressed. Annotation copyrighted by Book News, Inc., Portland, OR
Handbook of Clinical Neurology: Headache covers various aspects of headaches. It covers up-to-date information about the cultural developments and the scientific advances in the field of neurological science. One of the most frequent symptoms that people encounter is migraine or other type of headaches. At least 40% of neurological consultations are headache-related. With this, significant advances in basic and applied brain sciences have emerged in the field of headache-related problems. Divided into six sections, the book discusses the socioeconomic aspects of headaches, the contribution of biological sciences to the study of the pathophysiology of headache, and the management of headache and other related problems. It also deals with headache-related issues, such as pathogenic (chronobiological, endocrinological, and neuroimaging correlates), nosographic (i.e., migraine, vertigo, and headache in children), and treatment-related issues. The book will serve as a reference for researchers, clinical physicians, and other readers who want additional knowledge about the clinical features of headaches.
Explains the basics of the Macintosh OS X Panther server, covering installation and administration, services for files, directories, IP, security, and the Internet, and management tools for clients and workstations.
In As the Broken White Lines Become One, Michael Gehring recounts his spiritual journey through the landscape of late-twentieth-century southern American Christianity. This account depicts how and why he drifted away from the Roman Catholic Church, fellowshipped for a while with the Assemblies of God, sojourned for a prolonged time as an outsider to the institutional church, and eventually found a theological home within United Methodism. What follows is a spiritual journey with a lot of turns. The work is not intended to be a complete autobiography. Significant biographical details and relationships are not included as this narrative focuses on the shifting and sifting grounds of American Christian denominations. This chronicle primarily concerns the spiritual journey that led him to United Methodism and what it was like, not only to choose it, but also to inhabit it.
At mischief again, of course: always at it." Mrs Potter said this angrily, and with much emphasis, as she seized her son by the arm and dragged him out of a pool of dirty water, into which he had tumbled. "Always at mischief of one sort or another, he is," continued Mrs Potter, with increasing wrath, "morning, noon, and night-he is; tumblin' about an' smashin' things for ever he does; he'll break my heart at last-he will. There: take that!" "That," which poor little Tommy was desired to take, was a sounding box on the ear, accompanied by a violent shake of the arm which would have drawn that limb out of its socket if the child's bones and muscles had not been very tightly strung together.
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