More people were killed by smallpox during the twentieth century--over 300 million--than by all of the wars of that period combined. In 1918 and 1919, influenza virus claimed over 50 million lives. A century later, influenza is poised to return, ongoing plagues of HIV/AIDS and hepatitis infect millions, and Ebola, Zika, and West Nile viruses cause new concern and panic. The overlapping histories of humans and viruses are ancient. Earliest cities became both the cradle of civilization and breeding grounds for the first viral epidemics. This overlap is the focus of virologist/immunologist Michael Oldstone in Viruses, Plagues and History. Oldstone explains principles of viruses and epidemics while recounting stories of viruses and their impact on human history. This fully updated second edition includes engrossing new chapters on hepatitis, Zika, and contemporary threats such as the possible return of a catastrophic influenza, and the impact of fear of autism on vaccination efforts. This is a fascinating panorama of humankind's longstanding conflict with unseen viral enemies, both human successes--such as control of poliomyelitis, measles, smallpox and yellow fever, and continued dangers--such as HIV and Ebola. Impeccably researched and accessibly written, Viruses, Plagues and History will fascinate all with an interest in how viral illnesses alter the course of human history.
Oldstone presents a vivid history of a fascinating field, focusing on the most famous viruses humanity has battled: smallpox, polio, measles, yellow fever, and the new, unconquered strains of Ebola, Hantavirus, mad cow disease, and AIDS. 56 illustrations.
Ebola's Curse: 2013-2016 Outbreak in West Africa is about hemorrhagic fever viruses, especially Ebola, its initial origin in central Africa 1976, its unprecedented appearance in West Africa in 2013. The book records in sequence and detective style how the initial outbreak of Ebola from the index case in rural Guinea traveled to Sierra Leone, the work and fate of those working in the Kenema Government Hospital (KGH) isolation ward in Sierra Leone. The book provides vignettes of the three main players involved with Ebola at KGH, Sheik Khan, Pardis Sabeti, and Robert Garry. Khan was the head of the unit, declared a national hero by his Sierra Leone government. He died fighting Ebola and was/is recognized in the USA by American societies by awards created for his historic work and death. Pardis Sabeti, a geneticist from Harvard and Broad MIT Institute, who was honored as a "Scientist of the Year" by Time Magazine and the Smithsonian Institute. Robert Garry, head of the operation to fight hemorrhagic fevers and Ebola, shuttled between Tulane University, KGH, and The White House to make aware through the press and others the dilemma and tragedy that was unfolding, and the need to obtain additional medical and health care support and supplies. Sabeti and Garry currently work with Oldstone on Ebola at KGH and thus personal communication and knowledge was/is available to the author for the book. - Includes perspectives from the 2013-2016 outbreak in West Africa - Provides a detailed overview of the origins of Ebola virus through present day discoveries - Written with an integrative approach, incorporating scientific research with insights from the field on Public Health and Medical History
More people were killed by smallpox during the twentieth century--over 300 million--than by all of the wars of that period combined. In 1918 and 1919, influenza virus claimed over 50 million lives. A century later, influenza is poised to return, ongoing plagues of HIV/AIDS and hepatitis infect millions, and Ebola, Zika, and West Nile viruses cause new concern and panic. The overlapping histories of humans and viruses are ancient. Earliest cities became both the cradle of civilization and breeding grounds for the first viral epidemics. This overlap is the focus of virologist/immunologist Michael Oldstone in Viruses, Plagues and History. Oldstone explains principles of viruses and epidemics while recounting stories of viruses and their impact on human history. This fully updated second edition includes engrossing new chapters on hepatitis, Zika, and contemporary threats such as the possible return of a catastrophic influenza, and the impact of fear of autism on vaccination efforts. This is a fascinating panorama of humankind's longstanding conflict with unseen viral enemies, both human successes--such as control of poliomyelitis, measles, smallpox and yellow fever, and continued dangers--such as HIV and Ebola. Impeccably researched and accessibly written, Viruses, Plagues and History will fascinate all with an interest in how viral illnesses alter the course of human history.
Would you want to be cared for by a robot? Michael C. Brannigan’s Caregiving, Carebots, and Contagion explores caring robots’ lifesaving benefits, particularly during contagion, while probing the threat they pose to interpersonal engagement and genuine human caregiving. As our COVID-19 purgatory lingers on, caring robots will join our nursing and healthcare frontlines. Carebots can perform lifesaving tasks to minimize infection, safeguard vulnerable persons, and relieve caregivers of certain burdens. They also spark profound moral and existential questions: What is caring? How will we relate with each other? What does it mean to be human? Underscoring carebots' hands-on benefits, Brannigan also warns us of perils. They can be a dangerous lure in a culture that settles for substitutes and venerates the screen. Alerting us to the threatening prospect of carebots becoming our surrogate for interpersonal connection, he maintains they are not the culprits. The challenge lies in how we relate to them. While they beneficially complement our caregiving, carebots cannot replace human caring. Caring is a fundamentally human act and lies at the heart of ethics. As humans, we have a binding moral responsibility to care for the Other, and genuine caring demands our embodied, human-to-human presence.
The foremost text in this complex and fast-changing field, Medical Microbiology, 9th Edition, provides concise, up-to-date, and understandable explanations of key concepts in medical microbiology, immunology, and the microbes that cause human disease. Clear, engaging coverage of basic principles, immunology, laboratory diagnosis, bacteriology, virology, mycology, and parasitology help you master the essentials of microbiology―effectively preparing you for your coursework, exams, and beyond. - Features significant new information on the human microbiome and its influence on the immune and other body systems, and new developments in microbial diagnosis, treatment, diseases, and pathogens. - Updates every chapter with state-of-the-art information and current literature citations. - Summarizes detailed information in tabular format rather than in lengthy text. - Provides review questions at the end of each chapter that correlate basic science with clinical practice. - Features clinical cases that illustrate the epidemiology, diagnosis, and treatment of infectious diseases. - Introduces microbe chapters with summaries and trigger words for easy review. - Highlights the text with clear, colorful figures, clinical photographs, and images that help you visualize the clinical presentation of infections. - Offers additional study features online, including 200 self-assessment questions, microscopic images of the microbes, videos, and a new integrating chapter that provides hyperlinks between the microbes, the organ systems that they affect, and their diseases. - Evolve Instructor site with an image and video collection is available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com.
This book provides an intimate portrait of multiple outbreaks of Ebola in Africa and reveals how the results of that experience can help us fight COVID-19. Michael B.A. Oldstone, who led the Viral-Immunobiology Laboratory at the Scripps Research Institute worked with Ebola, teams up with Madeleine Rose Oldstone to give a detailed account of the 2013-2016 and 2018-2020 Ebola outbreaks. The authors trace the origin of the disease, its spread like a tsunami thru Guinea, Sierra Leone and Liberia, the collapse of economies, and the development of anti-viral therapies against Ebola. They compare the outbreaks of one of the world’s deadliest viruses with today’s struggle to overcome the COVID-19 pandemic. You will gain intimate knowledge of a deadly pathogen that devastated a region of the world that lacks resources to fight it, and learn why the world was unprepared for the Ebola outbreak. You will meet people who fought heroically with limited resources, including Sheik Kahn who died fighting Ebola and was declared a national hero by the Sierra Leone government, Pardis Sabeti, a geneticist working in infectious diseases from Harvard and MIT who was named “Scientist of the Year” by Time magazine, and Robert Garry, who headed the fight against viral hemorrhagic diseases and kept the White House and the press informed. Sabeti and Garry worked with Oldstone and provided information about the outbreak to the authors, making the narrative particularly incisive and timely. Ebola’s Evolution will give you a fast paced, detailed, and fascinating picture of a feared disease that killed thousands of people and threatening to become a global pandemic before it was stopped.
Ebola's Curse: 2013-2016 Outbreak in West Africa is about hemorrhagic fever viruses, especially Ebola, its initial origin in central Africa 1976, its unprecedented appearance in West Africa in 2013. The book records in sequence and detective style how the initial outbreak of Ebola from the index case in rural Guinea traveled to Sierra Leone, the work and fate of those working in the Kenema Government Hospital (KGH) isolation ward in Sierra Leone. The book provides vignettes of the three main players involved with Ebola at KGH, Sheik Khan, Pardis Sabeti, and Robert Garry. Khan was the head of the unit, declared a national hero by his Sierra Leone government. He died fighting Ebola and was/is recognized in the USA by American societies by awards created for his historic work and death. Pardis Sabeti, a geneticist from Harvard and Broad MIT Institute, who was honored as a "Scientist of the Year" by Time Magazine and the Smithsonian Institute. Robert Garry, head of the operation to fight hemorrhagic fevers and Ebola, shuttled between Tulane University, KGH, and The White House to make aware through the press and others the dilemma and tragedy that was unfolding, and the need to obtain additional medical and health care support and supplies. Sabeti and Garry currently work with Oldstone on Ebola at KGH and thus personal communication and knowledge was/is available to the author for the book. - Includes perspectives from the 2013-2016 outbreak in West Africa - Provides a detailed overview of the origins of Ebola virus through present day discoveries - Written with an integrative approach, incorporating scientific research with insights from the field on Public Health and Medical History
The Prose Reader promotes the skills of thinking, reading, and writing, enabling the user to think more clearly and logically--both in his/her mind and on paper. Prose models are intended to inspire, encouraging improved writing with a partnership with some of the best examples of professional prose available today. Each chapter begins with an explanation of a single technique, with essays that follow each chapter introduction selected from a wide variety of well-known contemporary authors. It helps readers discover various ways of thinking about and analyzing the essay. The book progresses from selections that require literal skills (Description, Narration, and Example) through readings involving more interpretation (Process Analysis, Division/Classification, Comparison/Contrast, and Definition) to essays that demand a high degree of analytical thought (Cause/Effect and Argument/Persuasion). An excellent and demanding reader for anyone interested in building their reading, writing, and thinking skills.
This book provides an intimate portrait of multiple outbreaks of Ebola in Africa and reveals how the results of that experience can help us fight COVID-19. Michael B.A. Oldstone, who led the Viral-Immunobiology Laboratory at the Scripps Research Institute worked with Ebola, teams up with Madeleine Rose Oldstone to give a detailed account of the 2013-2016 and 2018-2020 Ebola outbreaks. The authors trace the origin of the disease, its spread like a tsunami thru Guinea, Sierra Leone and Liberia, the collapse of economies, and the development of anti-viral therapies against Ebola. They compare the outbreaks of one of the world’s deadliest viruses with today’s struggle to overcome the COVID-19 pandemic. You will gain intimate knowledge of a deadly pathogen that devastated a region of the world that lacks resources to fight it, and learn why the world was unprepared for the Ebola outbreak. You will meet people who fought heroically with limited resources, including Sheik Kahn who died fighting Ebola and was declared a national hero by the Sierra Leone government, Pardis Sabeti, a geneticist working in infectious diseases from Harvard and MIT who was named “Scientist of the Year” by Time magazine, and Robert Garry, who headed the fight against viral hemorrhagic diseases and kept the White House and the press informed. Sabeti and Garry worked with Oldstone and provided information about the outbreak to the authors, making the narrative particularly incisive and timely. Ebola’s Evolution will give you a fast paced, detailed, and fascinating picture of a feared disease that killed thousands of people and threatening to become a global pandemic before it was stopped.
Measles virus, one of the most contagious of all human viruses, has been largely contained by the development and use of a vaccine that was introduced 50 years ago. These two volumes were timed to honor the introduction of the vaccine and to record the enormous advancements made in understanding the molecular and cell biology, pathogenesis, and control of this infectious disease. Where vaccine has been effectively delivered, endemic measles virus transmission has been eliminated. However, difficulties in vaccine delivery, lack of health care support and objection to vaccination in some communities continue to result in nearly 40 million cases and over 300,000 deaths per year from measles.
Measles virus, one of the most contagious of all human viruses, has been largely contained by the development and use of a vaccine that was introduced 50 years ago. These two volumes were timed to honor the introduction of the vaccine and to record the enormous advancements made in understanding the molecular and cell biology, pathogenesis, and control of this infectious disease. Where vaccine has been effectively delivered, endemic measles virus transmission has been eliminated. However, difficulties in vaccine delivery, lack of health care support and objection to vaccination in some communities continue to result in nearly 40 million cases and over 300,000 deaths per year from measles.
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