A logical approach to formulating a pathologic diagnosis from the diverse array of tissue received in the surgical pathology laboratory. The authors are both prominent gynaecologic pathologists, and this book is the result of their long-running Short Course presented at the International Academy of Pathology. Illustrations show typical artefacts and distortion and explain their impact on diagnostic interpretation, and each chapter includes a section on "Clinical Queries and Reporting" that summarises the features to be discussed in the final pathology report. Here is a strongly didactic approach to one of the most frequently ordered pathological examinations. You find superb illustrations on virtually every page and fast answers to everyday questions since emphasis is placed on clinically relevant material: commonly encountered specimens, common problems and common diagnostic issues.
With its large industrial base of ammunition plants and arsenals, the Army has more ordnance manufacturing capacity than it needs. This study proposes a strategic vision for this capacity and explores four options for managing it: privatization, creation of a federal government corporation, consolidation, and recapitalization on multifunction posts. It weighs the options from different perspectives, including feasibility, economic viability, and risk posed to national interests. ISBN: 0-8330-3322-0 Price: $30.00 Page count: 350
Practitioners of forensic medicine have various tools at their disposal to determine cause of death, and today‘s computed tomography (CT) can provide valuable clues if images are interpreted properly. This volume is a guide for the forensic pathologist who wants to use CT imaging to assist in determining the mechanism of injury that might have contributed to death. Enhanced with hundreds of CT images that clarify the text and case studies to put the material in context, the book gives a head-to-toe catalogue of various injuries and how they are represented on a CT scan.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
A history of the development of Chicago as a railroad hub, from its earliest days to the present, illustrated with color and black and white photographs, maps, and railroad memorabilia"--
Here it is: the first-time look at the remarkable American multinational mass media empire and its century of entertainment—the story of Twentieth Century Fox (1915–2015). Or, to borrow the title of a classic 1959 Fox film, The Best of Everything. This is the complete revelatory story—bookended by empire builders William Fox and Rupert Murdoch—aimed as both a grand, entertaining, nostalgic and picture-filled interactive read and the ultimate guide to all things Twentieth Century Fox. The controversies and scandals are here, as are the extraordinary achievements. Among other firsts, the book offers fun tours of its historic production and ranch facilities including never-before-told stories about its stars and creative personalities (Marilyn Monroe, Elvis Presley, James Dean, and Shirley Temple got started there). Finally, it is the first such work approved by the company and utilizing its own unique resources. The authors primarily tell a celebratory tale, but most importantly, an accurate one.
This third edition of Reconstructing Quaternary Environments has been completely revised and updated to provide a new account of the history and scale of environmental changes during the Quaternary. The evidence is extremely diverse ranging from landforms and sediments to fossil assemblages and geochemical data, and includes new data from terrestrial, marine and ice-core records. Dating methods are described and evaluated, while the principles and practices of Quaternary stratigraphy are also discussed. The volume concludes with a new chapter which considers some of the key questions about the nature, causes and consequences of global climatic and environmental change over a range of temporal scales. This synthesis builds on the methods and approaches described earlier in the book to show how a number of exciting ideas that have emerged over the last two decades are providing new insights into the operation of the global earth-ocean-atmosphere system, and are now central to many areas of contemporary Quaternary research. This comprehensive and dynamic textbook is richly illustrated throughout with full-colour figures and photographs. The book will be of interest to undergraduates, postgraduates and professionals in Earth Science, Environmental Science, Physical Geography, Geology, Botany, Zoology, Ecology, Archaeology and Anthropology
This issue of Endocrinology and Metabolism Clinics of North America provides the endocrinologist with essential updates on treatment of type 1 diabetes, with an eye toward future trends and developments. The Guest Editors brought together a remarkable group of notable authors, such as Paul Robertson, President of the National Diabetes Association. Topics covered include epidemiology; economics; contemporary management; inpatient management; update on insulin pumps and continuous glucose monitoring systems; update on studies aimed at interdicting and preventing type 1 diabetes; advances in the prediction, natural history, and mechanisms leading to type 1 diabetes; complications; hypoglycemia in type 1 diabetes; new lessons from animal models; the role of the gut in the genesis of type 1 diabetes and other autoimmune diseases; and an update on transplantation for reversing type 1 diabetes.
Largely reorganised and much expanded in this second edition, Practice and Procedures brings together in a single volume general methods of pain assessment and presents the wide range of therapies that can be provided by a range of health care disciplines. Authored by a multidisciplinary team of experts, chapters can stand alone for readers looking
This book analyzes the social construction of John Fitzgerald Kennedy's memory in the arts, literature, and in the many monuments erected in his honor.
This comprehensive reference guide reviews the literature concerning the impact of the automobile on American social, economic, and political history. Covering the complete history of the automobile to date, twelve chapters of bibliographic essays describe the important works in a series of related topics and provide broad thematic contexts. This work includes general histories of the automobile, the industry it spawned and labor-management relations, as well as biographies of famous automotive personalities. Focusing on books concerned with various social aspects, chapters discuss such issues as the car's influence on family life, youth, women, the elderly, minorities, literature, and leisure and recreation. Berger has also included works that investigate the government's role in aiding and regulating the automobile, with sections on roads and highways, safety, and pollution. The guide concludes with an overview of reference works and periodicals in the field and a description of selected research collections. The Automobile in American History and Culture provides a resource with which to examine the entire field and its structure. Popular culture scholars and enthusiasts involved in automotive research will appreciate the extensive scope of this reference. Cross-referenced throughout, it will serve as a valuable research tool.
As the modern food system continues to transform food - its composition, taste, availability, value, and appearance - consumers are increasingly confronted by legal and regulatory issues that affect us all on a daily basis. In Food Law in the United States, Michael T. Roberts addresses these issues in a comprehensive, systematic manner that lays out the national legal framework for the regulation of food and the legal tools that fill gaps in this framework, including litigation, state law, and private standards. Covering a broad expanse of topics including commerce, food safety, marketing, nutrition, and emerging food-systems issues such as local food, sustainability, security, urban agriculture, and equity, this book is an essential reference for lawyers, students, non-law professionals, and consumer advocates who must understand food law to advance their respective interests.
Applied Photometry, Radiometry, and Measurements of Optical Losses reviews and analyzes physical concepts of radiation transfer, providing quantitative foundation for the means of measurements of optical losses, which affect propagation and distribution of light waves in various media and in diverse optical systems and components. The comprehensive analysis of advanced methodologies for low-loss detection is outlined in comparison with the classic photometric and radiometric observations, having a broad range of techniques examined and summarized: from interferometric and calorimetric, resonator and polarization, phase-shift and ring-down decay, wavelength and frequency modulation to pulse separation and resonant, acousto-optic and emissive - subsequently compared to direct and balancing methods for studying free-space and polarization optics, fibers and waveguides. The material is focused on applying optical methods and procedures for evaluation of transparent, reflecting, scattering, absorbing, and aggregated objects, and for determination of power and energy parameters of radiation and color properties of light.
Carrying on the tradition established by its founding editor, the late Dr. Martin Abeloff, the 4th Edition of this respected reference synthesizes all of the latest oncology knowledge in one practical, clinically focused, easy-to-use volume. It incorporates basic science, pathology, diagnosis, management, outcomes, rehabilitation, and prevention – all in one convenient resource – equipping you to overcome your toughest clinical challenges. What's more, you can access the complete contents of this Expert Consult title online, and tap into its unparalleled guidance wherever and whenever you need it most! Equips you to select the most appropriate tests and imaging studies for diagnosing and staging each type of cancer, and manage your patients most effectively using all of the latest techniques and approaches. Explores all of the latest scientific discoveries' implications for cancer diagnosis and management. Employs a multidisciplinary approach - with contributions from pathologists, radiation oncologists, medical oncologists, and surgical oncologists - for well-rounded perspectives on the problems you face. Offers a user-friendly layout with a consistent chapter format • summary boxes • a full-color design • and more than 1,445 illustrations (1,200 in full color), to make reference easy and efficient. Offers access to the book's complete contents online – fully searchable – from anyplace with an Internet connection. Presents discussions on cutting-edge new topics including nanotechnology, functional imaging, signal transduction inhibitors, hormone modulators, complications of transplantation, and much more. Includes an expanded color art program that highlights key points, illustrates relevant science and clinical problems, and enhances your understanding of complex concepts.
Although the present edition of Fundamentals of Creep in Metals and Alloys remains broadly up to date for metals, there are a range of improvements and updates that are either desirable, or required, in order to ensure that the book continues to meet the needs of researchers and scholars in the general area of creep plasticity. Besides updating the areas currently covered in the second edition with recent advances, the third edition will broaden its scope beyond metals and alloys to include ceramics, covalent solids, minerals and polymers, thus addressing the fundamentals of creep in all basic classes of materials. - Numerous line drawings with consistent format and units allow easy comparison of the behavior of a very wide range of materials - Transmission electron micrographs provide direct insight into the basic microstructure of metals deforming at high temperatures - Extensive literature review of about 1000 references provides an excellent overview of the field
This book describes the important role that the transfer of genes between organisms has played during the origin and evolution of humans, and the evolution of organisms on which the human species depends for shelter, sustenance and companionship.
Operative Techniques in Surgery is a new comprehensive, 2-volume surgical atlas that helps youmaster a full range of general surgical procedures. Ideal for residents as well as experienced surgeons, it guides you step-by-step through each technique using concise, bulleted text, full-color illustrations, and intraoperative photographs to clarify exactly what to look for and how to proceed.
Learn the best time to do everything -- from drink your coffee to have sex or go for a run -- according to your body's chronotype. Most advice centers on what to do, or how to do it, and ignores the when of success. But exciting new research proves there is a right time to do just about everything, based on our biology and hormones. As Dr. Michael Breus proves in The Power Of When, working with your body's inner clock for maximum health, happiness, and productivity is easy, exciting, and fun. The Power Of When presents a groundbreaking program for getting back in sync with your natural rhythm by making minor changes to your daily routine. After you've taken Dr. Breus's comprehensive Bio-Time Quiz to figure out your chronotype (are you a Bear, Lion, Dolphin or Wolf?), you'll find out the best time to do over 50 different activities. Featuring a foreword by Mehmet C. Oz, MD, and packed with fascinating facts, fun personality quizzes, and easy-to-follow guidelines, The Power Of When is the ultimate "lifehack" to help you achieve your goals.
A comprehensive introduction to interval logic and duration calculus for modelling, analysing and verifying real-time systems. The Duration Calculus (DC) represents a logical approach to formal design of real-time systems. In DC real numbers are used to model time and Boolean-valued (i.e. {0,1}-valued) functions over time to model states of real-time systems. The duration of a state in a time interval is the accumulated presence time of the state in the interval. DC extends interval logic to a calculus to specify and reason about properties of state durations. The text covers theory (completeness, decidability, undecidability, model-checking), results, as well as case studies (Deadline Driven Scheduler).
Ipilimumab is the first drug to show a survival benefit for patients with advanced melanoma and was approved by the US Food and Drug Administration in March of 2011. Ipilimumab enhances antitumor immunity by enhancing T-cell function by blocking the negative regulatory molecule, cytotoxic T-lymphocyte antigen 4 (CTLA-4). Unlike traditional cancer therapy, ipilimumab’s effects may be delayed and occur after initial apparent disease progression. A distinct set of side effects have been described, and ongoing efforts continue to characterize immunologic changes associated with patients who benefit from therapy. Efforts to characterize ipilimumab’s clinical activity in malignancies other than melanoma are ongoing.
Materials and Sustainable Development, Second Edition, written by noted materials selection authority Mike Ashby, provides a structure and framework for analyzing sustainable development and the role of materials in it. The book's aim is to introduce ways of exploring sustainable development to readers in a way that avoids simplistic interpretations and approaches complexity in a systematic way. There is no completely 'right' answer to questions of sustainable development, instead, there is a thoughtful, well-researched response that recognizes concerns of stakeholders, conflicting priorities, and the economic, legal and social aspects of the technology and its environmental legacy. The intent of the book is not to offer solutions to sustainability challenges but rather to improve the quality of discussion and enable informed, balanced debate. This updated edition has been updated to reflect new insights, regulatory trends and other developments that have occurred since publication of the previous edition. - Describes sustainable development in increasingly detailed progression, from a broad overview to specific tools and methods - Includes updated chapter length case studies on topics such as biopolymers, electric cars, bamboo, and lighting that vividly illustrate the sustainable development process from a materials perspective - Covers business and economic aspects in chapters on corporate sustainability and the "circular materials economy
This is a translation, with a commentary and a long contextualizing introduction, of the only major work of Han (206 B.C. to 220 A.D.) philosophy that is still available in complete form. It is the first translation of the work into a European language and provides unique access to this formative period in Chinese history. Because Yang Hsiung's interpretations drew upon a variety of pre-Han sources and then dominated Confucian learning until the twelfth century, this text is also a valuable resource on early Chinese history, philosophy, and culture beyond the Han period. The T'ai hsüan is also one of the world's great philosophic poems comparable in scale and grandeur to Lucretius' De rerum naturum. Nathan Sivin has written that this is one of the titles on the short list of Chinese books every cultivated person should read. Han thinkers saw in this text a compelling restatement of Confucian doctrine that addressed the major objections posed by rival schools including Mohism, Taoism, Legalism and Yin-Yang Five Phase Theory. Since this Han amalgam formed the basis for the state ideology of China from 134 B.C. to 1911, an ideology that in turn provided the intellectual foundations for the Japanese and Korean states, the importance of this book can hardly be overestimated.
Few areas of biomedical research provide greater opportunities to capitalize upon the revolution in genomics and molecular biology than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy in the Brain: From Bench to Bedside represents the definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped to create the field as well as those who are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects which would be of interest to anyone who is currently using or contemplating exploring gene therapy for neurobiological applications. Basic gene transfer technologies are discussed, with particular emphases upon novel vehicles, immunological issues and the role of gene therapy in stem cells. Numerous research applications are reviewed, particularly in complex fields such as behavioral neurobiology. Several preclinical areas are also covered which are likely to translate into clinical studies in the near future, including epilepsy, pain and amyotrophic lateral sclerosis. Among the most exciting advances in recent years has been the use of neurological gene therapy in human clinical trials, including Parkinson's disease, Canavan disease and Batten disease. Finally, readers will find "insider" information on technological and regulatory issues which can often limit effective translation of even the most promising idea into clinical use. This work provides up-to-date information and key insights into those gene therapy issues which are important to both scientists and clinicians focusing upon the brain and central nervous system.
Financial struggles of American families are headline news. In communities across the nation, families feel the pinch of stagnant and sometimes declining incomes. Many have not recovered from the Great Recession, when millions lost their homes and retirement savings. They are bombarded daily with vexing financial decisions: Which bills to pay? Where to cash checks? How to cover an emergency? How to improve a credit report? How to bank online? How to save for the future? Low- and moderate-income families have few places to turn for guidance on financial matters. Not many can afford to pay a financial advisor to help navigate an increasingly complex financial world. They do their best with advice from family and trusted individuals. Social workers, financial counselors, and human services professionals can help. As "first responders," they assist families and help in finding financial support from public and private sources. But these professionals are too often unprepared to address the full range of financial troubles of ordinary working families. Financial Capability and Asset Building in Vulnerable Households prepares social workers, financial counselors, and other human service professionals for financial practice with vulnerable families. Building on more than 20 years of research, the book sets the stage with key concepts, historical antecedents, and current financial challenges of families in America. It provides knowledge and tools to assist families in pressing financial circumstances, and offers a lifespan perspective of financial capability and environmental influences on financial behaviors and actions. Furthermore, the text details practice principles and skills for direct interventions, as well as for designing financial services and policy innovations. It is an essential resource for preparing the next generation of practitioners who can enable families to achieve economic security and development.
Clinical Chemistry: Principles, Techniques, and Correlations, Enhanced Eighth Edition demonstrates the how, what, why, and when of clinical testing and testing correlations to help you develop the interpretive and analytic skills you’ll need in your future career.
This accessible introduction provides social work students and practitioners with the knowledge they need both to evaluate research and to apply it to their own practice. Exploring a range of research methodologies, the author discusses the strengths and limitations of each and shows the reader how to identify the assumptions underlying them.
The book discusses a new approach to the classification problem following the decision support orientation of multicriteria decision aid. The book reviews the existing research on the development of classification methods, investigating the corresponding model development procedures, and providing a thorough analysis of their performance both in experimental situations and real-world problems from the field of finance. Audience: Researchers and professionals working in management science, decision analysis, operations research, financial/banking analysis, economics, statistics, computer science, as well as graduate students in management science and operations research.
This book provides a new point of view on the field of financial engineering, through the application of multicriteria intelligent decision aiding systems. The aim of the book is to provide a review of the research in the area and to explore the adequacy of the tools and systems developed according to this innovative approach in addressing complex financial decision problems, encountered within the field of financial engineering. Audience: Researchers and professionals such as financial managers, financial engineers, investors, operations research specialists, computer scientists, management scientists and economists.
Recognized as the most prestigious, comprehensive text on Global Health for GRADUATE programs in public and global health. Global Health, Third Edition (formerly titled International Public Health) brings together contributions from the world's leading authorities into a single comprehensive text. It thoroughly examines the wide range of global health challenges facing low and middle income countries today and the various approaches nations adopt to deal with them. These challenges include measurement of health status, infectious and chronic diseases, injuries, nutrition, reproductive health, global environmental health and complex emergencies. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.
CBT and EXISTENTIAL PSYCHOLOGY Explore the possibilities and challenges of bringing two highly diverse disciplines—CBT and existential therapy—into dialogue In CBT and Existential Psychology: Philosophy, Psychology and Therapy, distinguished clinical psychologist Dr Michael Worrell delivers a singular exploration of the relationship between diverse forms of contemporary cognitive behaviour therapy and existential phenomenology. Written for both experienced and beginning CBT therapists, as well as therapists who practice from an existential perspective, this book clarifies and discusses the potential and challenges presented when these two different schools of thought and practice are brought into dialogue. The author outlines, in accessible fashion, the implications and possibilities offered by the combination of CBT and existential practice. He also presents a series of discussions with the highly experienced CBT therapists, researchers, and trainers, Tomas Heidenreich and Alexander Noyon, and existential therapy leader Ernesto Spinelli. The book includes a series of “existential reflections” and experiential exercises to allow the reader to develop an understanding of descriptive phenomenological approaches to therapeutic conversations. Readers will also find: A thorough introduction to existential philosophy, psychology, and therapy, including the theory and practice of existential therapy Comprehensive discussions of cognitive and behavioural psychotherapies, including Beckian CBT, schema-focused therapies, and constructivist, narrative, and postmodern CBT In-depth explorations of existential challenges and contributions to therapy, including discussions of anxiety, possibility, and uncertainty Enlightening dialogues on CBT and existential psychology with Tomas Heidenreich, Alexander Noyon, and Ernesto Spinelli Perfect for beginning and advanced CBT and existential therapists, CBT and Existential Psychology: Philosophy, Psychology and Therapy will also earn a place in the libraries of trainee clinical and counselling psychologists, as well as integrative and humanistic psychotherapists.
Radio systems capable of localization have emerging applications in homeland security, law enforcement, emergency response, defense command and control, multi-robot coordination and vehicle-to-vehicle and vehicle-to-pedestrian collision avoidance. In fact, high resolution localization is vital for many applications, including: traffic alert, emergency services, e.g., indoor localization for firefighters, and battlefield command and control. These systems promise to dramatically reduce society's vulnerabilities to catastrophic events and improve its quality of of life. While work this important area is progressing, limited resources are available to support graduate students and researchers in this important area. Specifically, a limited number of books has been published in this area covering selected subjects. This comprehensive handbook offers gaps of available localization books presenting in-depth coverage from fundamentals of coordinates to advanced application examples.
With an emphasis on global advantage, the text offers a comprehensive examination of regional and international issues to provide a complete, accurate and up-to-date explanation of the strategic management process. New coverage on environmental concerns and emerging technologies as well as examples and cases from Australia, New Zealand and Asia-Pacific serve to engage students while updated international content demonstrates how strategic management is used in the global economy. The text takes a 'resource-based' approach, which requires the examining of a firm's unique bundling of its internal resources. This text is appropriate for upper-level undergrad, usually third year; post grad in Masters courses.
Emerging Phytosynthesized Nanomaterials for Biomedical Applications provides readers with an increased understanding of the efficacy of phytochemicals obtained from plant extracts for the synthesis of nanomaterials, mechanism of formation, and the development of functional composites, all while still minimizing toxicity to humans and the environment. The book presents various novel biomedical applications of phytosynthesized nanomaterials for cancer, diabetes and cardiovascular treatment, drug delivery, antimicrobial agents, orthopedics, and biosensors, as well as pharmaceutical product development. This is an important reference source for biomaterials scientists and plant scientists looking to increase their understanding of how photosynthesized nanomaterials can be used in biomedical applications. - Outlines the significance of phytochemicals in nanomaterial biosynthesis for sustainable applications - Explores the efficiency of phytosynthesized nanomaterials in various biomedical applications, including cancer, diabetes and cardiovascular ailment treatment, drug delivery, antimicrobial agents, orthopedics and biosensors - Assesses the potential limitations of phytosynthesized nanomaterials and ways to mitigate these challenges for emerging applications, including wound healing plasters, nanorobots, artificial organs and antimicrobial textiles
50th Anniversary Edition of the groundbreaking case-based pharmacotherapy text, now a convenient two-volume set. Celebrating 50 years of excellence, Applied Therapeutics, 12th Edition, features contributions from more than 200 experienced clinicians. This acclaimed case-based approach promotes mastery and application of the fundamentals of drug therapeutics, guiding users from General Principles to specific disease coverage with accompanying problem-solving techniques that help users devise effective evidence-based drug treatment plans. Now in full color, the 12th Edition has been thoroughly updated throughout to reflect the ever-changing spectrum of drug knowledge and therapeutic approaches. New chapters ensure contemporary relevance and up-to-date IPE case studies train users to think like clinicians and confidently prepare for practice.
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