Historians have long held that during the decades from the end of the Habsburg-Valois Wars in 1559 until the outbreak in 1618 of the Thirty Years' War, Spanish domination of Italy was so complete that one can refer to the period as a "pax hispanica." In this book, based on extensive research in the papers of the ambassadors who represented Charles V and Philip II, Michael J. Levin instead reveals the true fragility of Spanish control and the ambiguous nature of its impact on Italian political and cultural life.While exploring the nature and weaknesses of Spanish imperialism in the sixteenth century, Levin focuses on the activities of Spain's emissaries in Rome and Venice, drawing us into a world of intrigue and occasional violence as the Spaniards attempted to manipulate the crosscurrents of Italian and papal politics to serve their own ends. Levin's often-colorful account uncovers the vibrant world of late Renaissance diplomacy in which popes were forced to flee down secret staircases and ambassadors too often only narrowly avoided assassination. An important contribution to our understanding of the nature and limits of the Spanish imperial system, Agents of Empire more broadly highlights the centrality of diplomatic history to any consideration of the politics of empire.
Measurements in Evaluating Science Education is a comprehensive, intuitive guide to many of the key instruments created to assess science education environments, learning, and instruction. Nearly 70 different surveys, tests, scales, and other metrics are organized according to the qualities the measures attempt to gauge, such as attitudes toward science, beliefs and misconceptions, self-efficacy, and content knowledge. Summaries of each instrument, usage information, developmental history and validation, and reported psychometric properties make this an essential reference for anyone interested in understanding science education assessment.
The Sixth Edition of a classic in organic chemistry continues its tradition of excellence Now in its sixth edition, March's Advanced Organic Chemistry remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions. The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease. New features include: More than 25,000 references to the literature to facilitate further research Revised mechanisms, where required, that explain concepts in clear modern terms Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries A revised Appendix B to facilitate correlating chapter sections with synthetic transformations
Hilbert's talk at the second International Congress of 1900 in Paris marked the beginning of a new era in the calculus of variations. A development began which, within a few decades, brought tremendous success, highlighted by the 1929 theorem of Ljusternik and Schnirelman on the existence of three distinct prime closed geodesics on any compact surface of genus zero, and the 1930/31 solution of Plateau's problem by Douglas and Radò. The book gives a concise introduction to variational methods and presents an overview of areas of current research in this field. This new edition has been substantially enlarged, a new chapter on the Yamabe problem has been added and the references have been updated. All topics are illustrated by carefully chosen examples, representing the current state of the art in their field.
Most research about financial stability and sustainable growth focuses on the financial sector and macroeconomics and neglects the real sector, microeconomics and psychology issues. Real-sector and financial-sectors linkages are increasing and are a foundation of economic/social/environmental/urban sustainability, given financial crises, noise, internet, “transition economics”, disintermediation, demographics and inequality around the world. Within complex systems theory framework, this book analyses some multi-sided mechanisms and risk-perception that can have symbiotic relationships with financial stability, systemic risk and/or sustainable growth. Within the context of Regret Minimization, MN-Transferable Utility and WTAL, new theories-of-the-firm are developed that consider sustainable growth, price stability, globalization, financial stability and birth-to-death evolutions of firms. This book introduces new behaviour theories pertaining to real estate and intangibles, which can affect the evolutions of risk-taking and risk perception within organizations and investment entities. The chapters address elements of the dilemma of often divergent risk perceptions of, and risk-taking by corporate executives, regulators and investment managers.
This volume provides the texts of lectures given by L. Ambrosio, L. Caffarelli, M. Crandall, L.C. Evans, N. Fusco at the Summer course held in Cetraro, Italy in 2005. These are introductory reports on current research by world leaders in the fields of calculus of variations and partial differential equations. Coverage includes transport equations for nonsmooth vector fields, viscosity methods for the infinite Laplacian, and geometrical aspects of symmetrization.
While our five senses are doing a reasonably good job at representing the world around us on a macro-scale, we have no existing intuitive representation of the nanoworld, ruled by laws entirely foreign to our experience. This is where molecules mingle to create proteins; where you wouldn't recognize water as a liquid; and where minute morphological changes would reveal how much 'solid' things, such as the ground or houses, are constantly vibrating and moving. Following in the footsteps of Nano-Society and Nanotechnology: The Future is Tiny, this title introduces a new collection of stories demonstrating recent research in the field of nanotechnology. This drives home the fact that a plethora of nanotechnology R&D will become an integral part of improved and entirely novel materials, products, and applications yet will remain entirely invisible to the user. The book gives a personal perspective on how nanotechnologies are created and developed, and will appeal to anyone who has an interest in the research and future of nanotechnology. Reviews of Nanotechnology: The Future is Tiny: 'The book is recommended not only to all interested scientists, but also to students who are looking for a quick and clear introduction to various research areas of nanotechnology' Angew. Chem., 2017, 56(26), 7351–7351 'Once you start reading you will find it very difficult to stop' Chromatographia, 2017, 80, 1821
Clinical Anesthesia, Seventh Edition covers the full spectrum of clinical options, providing insightful coverage of pharmacology, physiology, co-existing diseases, and surgical procedures. This classic book is unmatched for its clarity and depth of coverage. *This version does not support the video and update content that is included with the print edition. Key Features: • Formatted to comply with Kindle specifications for easy reading • Comprehensive and heavily illustrated • Full color throughout • Key Points begin each chapter and are labeled throughout the chapter where they are discussed at length • Key References are highlighted • Written and edited by acknowledged leaders in the field • New chapter on Anesthesia for Laparoscopic and Robotic Surgery Whether you’re brushing up on the basics, or preparing for a complicated case, the digital version will let you take the content wherever you go.
Clinical Anesthesia, Seventh Edition covers the full spectrum of clinical options, providing insightful coverage of pharmacology, physiology, co-existing diseases, and surgical procedures. This classic book is unmatched for its clarity and depth of coverage. *This version does not support the video and update content that is included with the print edition. Key Features: • Formatted to comply with Kindle specifications for easy reading • Comprehensive and heavily illustrated • Full color throughout • Key Points begin each chapter and are labeled throughout the chapter where they are discussed at length • Key References are highlighted • Written and edited by acknowledged leaders in the field • New chapter on Anesthesia for Laparoscopic and Robotic Surgery Whether you’re brushing up on the basics, or preparing for a complicated case, the digital version will let you take the content wherever you go.
Main headings: I. Basic concepts of pulsatile arterial hemodynamics. - II. Pathophysiological mechanisms. - III. Arterial stiffness, wave reflections, cardiovascular risk and end-organ damage. - IV. Clinical aspects of arterial stiffness and wave reflections. - V. Therapeutic aspects of arterial stiffness and wave reflections.
A major reevaluation of Caravaggio from one of today's leading art historians This is a groundbreaking examination of one of the most important artists in the Western tradition by one of the leading art historians and critics of the past half-century. In his first extended consideration of the Italian Baroque painter Michelangelo Merisi da Caravaggio (1573-1610), Michael Fried offers a transformative account of the artist's revolutionary achievement. Based on the A. W. Mellon Lectures in the Fine Arts delivered at the National Gallery of Art, The Moment of Caravaggio displays Fried's unique combination of interpretive brilliance, historical seriousness, and theoretical sophistication, providing sustained and unexpected readings of a wide range of major works, from the early Boy Bitten by a Lizard to the late Martyrdom of Saint Ursula. The result is an electrifying new perspective on a crucial episode in the history of European painting. Focusing on the emergence of the full-blown "gallery picture" in Rome during the last decade of the sixteenth century and the first decades of the seventeenth, Fried draws forth an expansive argument, one that leads to a radically revisionist account of Caravaggio's relation to the self-portrait; of the role of extreme violence in his art, as epitomized by scenes of decapitation; and of the deep structure of his epoch-defining realism. Fried also gives considerable attention to the art of Caravaggio's great rival, Annibale Carracci, as well as to the work of Caravaggio's followers, including Orazio and Artemisia Gentileschi, Bartolomeo Manfredi, and Valentin de Boulogne. Please note: All images in this ebook are presented in black and white and have been reduced in size.
This book provides a down-to-earth account of the virtues and failures of environmental risk assessment. The assessment process involves politics, technology, and issues of social choice, an unstructured grouping that often presents contradictory and confusing standpoints: the virtues of science and the scientific method are extolled on the one hand and condemned on the other; no viable solutions are offered; and there is no real understanding of the issues being discussed. This chaotic situation is analyzed using cultural theory, to offer a powerful and groundbreaking account of such topics as technological decision making, politics, energy, engineering, and technology as a whole.
The Mediterranean was one of Napoleon's greatest spheres of influence. With territory in Spain, Italy and, of course, France, Napoleon's regime dominated the Great Sea for much of the early nineteenth century. The 'Napoleonic Mediterranean' was composed of almost the entirety of the western, European lands bordering its northern shores, however tenuously many of those shores were held. The disastrous attempt to conquer Egypt in 1798-99, and the rapid loss of Malta to the British, sealed its eastward and southern limits. None of Napoleon's Mediterranean possessions were easily held; they were volatile societies which showed determined resistance to the new state forged by the French Revolution. In this book, acclaimed historian and biographer of Napoleon, Michael Broers looks at the similarities and differences between Napoleon's Mediterranean imperial possessions. He considers the process of political, military and legal administration as well as the challenges faced by Napoleon's Prefects in overcoming hostility in the local population. With chapters covering a range of imperial territories, this book is a unique and valuable addition to the historical literature on Napoleonic Europe and the process and practice of imperialism.
The Italian Wars 1494–1559 outlines the major impact that these wars had, not just on the history of Italy, but on the history of Europe as a whole. It provides the first detailed account of the entire course of the wars, covering all the campaigns and placing the military conflicts in their political, diplomatic, social and economic contexts. Throughout the book, new developments in military tactics, the composition of armies, the balance between infantry and cavalry, and the use of firearms are described and analysed. How Italians of all sectors of society reacted to the wars and the inevitable political and social change that they brought about is also examined, offering a view of the wars from a variety of perspectives. Fully updated and containing a range of maps as well as a brand-new chapter on propaganda and images of war, this second edition of The Italian Wars 1494–1559 is essential reading for all students of Renaissance and military history.
The first large-scale study of how fifteenth-century motets were used across Western Europe, dispelling the mysteries surrounding these outstanding works.
Necrotizing enterocolitis is an acute inflammatory necrosis of bowel that primarily afflicts premature infants in the neonatal intensive care unit setting. Although patients who develop this disease have high morbidity and mortality rates, the pathogenesis is poorly understood, and therefore there are no specific preventive or treatment strategies that have been clearly effective. Recent studies have suggested that the pathophysiology of necrotizing enterocolitis includes alterations in the inflammatory response leading to dysregulated pro-inflammatory signaling in premature infants, as well as abnormal intestinal bacterial colonization patterns that can activate these inflammatory pathways, and these factors are discussed in depth in the following chapters. While human milk feedings are currently the standard of care for the prevention of this challenging condition, new approaches will be described based on sound evidence that might have a significant impact for premature infants throughout the world.
Visualization and visual analytics are powerful concepts for exploring data from various application domains. The endless number of possible parameters and the many ways to combine visual variables as well as algorithms and interaction techniques create lots of possibilities for building such techniques and tools. The major goal of those tools is to include the human users with their tasks at hand, their hypotheses, and research questions to provide ways to find solutions to their problems or at least to hint them in a certain direction to come closer to a problem solution. However, due to the sheer number of design variations, it is unclear which technique is suitable for those tasks at hand, requiring some kind of user evaluation to figure out how the human users perform while solving their tasks. The technology of eye tracking has existed for a long time; however, it has only recently been applied to visualization and visual analytics as a means to provide insights to the users’ visual attention behavior. This generates another kind of dataset that has a spatio-temporal nature and hence demands for advanced data science and visual analytics concepts to find insights into the recorded eye movement data, either as a post process or even in real-time. This book describes aspects from the interdisciplinary field of visual analytics, but also discusses more general approaches from the field of visualization as well as algorithms and data handling. A major part of the book covers research on those aspects under the light and perspective of eye tracking, building synergy effects between both fields – eye tracking and visual analytics – in both directions, i.e. eye tracking applied to visual analytics and visual analytics applied to eye tracking data. Technical topics discussed in the book include: • Visualization; • Visual Analytics; • User Evaluation; • Eye Tracking; • Eye Tracking Data Analytics; Eye Tracking and Visual Analytics includes more than 500 references from the fields of visualization, visual analytics, user evaluation, eye tracking, and data science, all fields which have their roots in computer science. Eye Tracking and Visual Analytics is written for researchers in both academia and industry, particularly newcomers starting their PhD, but also for PostDocs and professionals with a longer research history in one or more of the covered research fields. Moreover, it can be used to get an overview about one or more of the involved fields and to understand the interface and synergy effects between all of those fields. The book might even be used for teaching lectures in the fields of information visualization, visual analytics, and/or eye tracking.
Light therapy' is established worldwide as the treatment of choice for seasonal affective disorder. It is also successfuly used in nonseasonal depression, as well as for many other psychiatric and neurologic illnesses, and in sleep medicine. Wake therapy is the fastest antidepressant known. Imaging studies show that both methods share neurobiological substrates with antidepressants, but act much faster. 'Chronotherapeutics' the combination of light and wake therapy achieves rapid results and, by reducing residual symptoms, also minimises relapse. Written by three prominent clinical and research experts in biological rhythms, this manual aims to broaden knowledge and practical application of these non-pharmacologic interventions for bipolar and unipolar disorders. Clinical understanding is deepened by an explanation of the circadian timing system and sleep regulatory mechanisms which underlie the novel treatment strategy. The step-by-step guide and description of the interventions in centers throughout the world provides clear hands-on instructions, supported by a solid body of clinical research. The first edition of 'Chronotherapeutics for Affective Disorders' has kindled a network of psychiatrists and psychologists who are actively introducing these treatments for their inpatients and outpatients. This manual is also essential reading for primary care physicians, sleep medicine specialists and health care administrators.
Buy a new version of this textbook and receive access to the Connected eBook with Study Center on CasebookConnect, including: lifetime access to the online ebook with highlight, annotation, and search capabilities; practice questions from your favorite study aids; an outline tool and other helpful resources. Connected eBooks provide what you need most to be successful in your law school classes. Learn more about Connected eBooks. A problem-based Evidence coursebook that presents the Federal Rules of Evidence in context, illuminates the rules’ underlying theories and perspectives, and provides a fully updated and systematic account of the law in a student-friendly hornbook-style format. The material is accompanied with straightforward and systematic explanations. Lively discussion and interesting problems (rather than numerous appellate case excerpts) engage students in understanding the principles, policies, and debates that surround evidence law. The book also contains self-assessment sections in each chapter that teach students how to identify and resolve legal issues and succeed in the final exam. To sum up: this book stands out as “all in one”: it gives students of evidence an up-to-date comprehensive account of the law; it explains complex evidentiary issues in a straightforward and systematic fashion; and it also tells students what their exam will look like and how to succeed in it. New to the Seventh Edition: A new case file to introduce numerous evidence issues throughout the semester, with spin-off problems in each chapter. Updated doctrine, including application of evidence rules to electronic evidence and the online environment. Professors and students will benefit from: An opening case file introducing students to the process of analyzing evidence in terms of the essential elements of a legal dispute, serving as an effective introduction to much of the course to follow A wide range of real-world problems exposes students to the depth and complexity of the Rules of Evidence Every chapter addresses basic rules interpretation, essential policy, and connects theory to practice Assessment problems (modeled on exam questions) at the end of each chapter, including answers with explanations Teaching materials Include: Updated and streamlined Teacher’s Manual, including sample syllabi for both 4- and 3-credit courses, transition guide for each chapter, teaching guidance, and answers to all the problems in the book Problems Supplement that includes most problems deleted from prior editions
Turn to the field's definitive text for a thoroughunderstanding of the clinical and scientific aspects of pulmonary medicine Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the underlying basic and applied science upon which clinical practice is based. The Fifth Edition, with 270 contributing authors, includes over 2,000 illustrations, 60 videos, and 18,000 references. The book opens with a comprehensive overview of the scientific basis of lung function in health and disease. It then provides detailed coverage of the broad array of diseases and disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms,respiratory infections, and respiratory failure, among others. The Fifth Edition has been completely updated to reflect the many advancements that have been made in pulmonary medicine over the past few years, including: Molecular development of the lung Stem cells and respiratory disease Genetics of pulmonary disease and the growth of personalized medicine Technical advances in lung transplantation Growth in immunology and immunosuppressive management Diagnosis and treatment of pulmonary hypertension Circadian rhythms and sleep biology Rapid evolution in lung imaging techniques, including functional imaging Contemporary interventional bronchoscopic techniques You will also find state-of-the-art coverage of thelatest topics in critical care medicine, including: Early diagnosis and management of sepsis Multiple organ dysfunction syndrome (MODS) Acute respiratory distress syndrome (ARDS) Management of agitation and delirium in the ICU The newly defined entity of "chronic critical illness
First Prize, Orthopaedics and Rheumatology, BMA Awards 2009 This state-of-the-art reference provides current insights into the etiology, diagnosis and management of rheumatoid arthritis. Leading international authorities in RA examine all of the latest scientific and clinical developments in understanding and managing this challenging disease, including new concepts in pathogenesis, epidemiology, risk factors, imaging, clinical outcomes and treatment. It’s the guidance you need to offer optimal care to your patients with rheumatoid arthritis. Presents the work of leading international experts in rheumatoid arthritis for guidance you can trust. Provides the very latest understanding of the pathogenesis of rheumatoid arthritis, including molecular pathways/mechanisms, and genetic and environmental factors that instigate and drive the disease. Includes comprehensive coverage of clinical features of rheumatoid arthritis including articular, peri-articular and extra-articular manifestations, comorbidities, and outcome measures—disease activity, joint assessment, imaging, and more—for expert diagnosis and monitoring of disease progression. Examines evidence-based treatment options—including traditional and biologic DMARDs and combination therapies—as well as promising therapies on the horizon, placing up-to-date guidance on disease modifying or disease controlling agents at your fingertips.
Discover Europe's best-dressed city: Milan, home of some of the world's most luxurious clothes shops and most exclusive fashion houses. The guide uncovers all the best places to window-shop and to pick up a designer label. It also explores the city's remarkable architectural heritage: from Galleria Vittorio Emanuele--the elegant glass-roofed arcade that encloses many of the finest boutiques, to the unmissable Piazza del Duomo--with its enormous 14th-century marble cathedral. Milan also finds time for art--with four world-renowned galleries and Leonardo's 'Last Supper'; and for music--La Scala is the centre of Italian opera. After covering the highlights in depth, the guide includes extensive listings of the hidden gems, the little galleries, theatres, and concert venues that make the city tick. Detailed reviews of the best places to stay and eat out, along with full-color photographs, plenty of maps, and valuable practical information make this an essential companion for a business trip, shopping expedition, or art-lover's pilgrimage.
The definitive guide to the clinical and scientific aspects of pulmonary medicine―fully updated with the latest advances in the field A Doody's Core Title for 2023! Fishman’s Pulmonary Diseases and Disorders delivers unparalleled coverage of pulmonary medicine. With nearly 2500 illustrations, 60 videos, and 22,000 references, this peerless, two-volume resource provides a comprehensive overview of the scientific basis of lung function in health and disease. You’ll find detailed coverage of the broad array of disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms, respiratory infections, and respiratory failure. In addition, you’ll learn about all the latest advances, including molecular development of the lung, stem cells and respiratory disease, the genetics of pulmonary disease, the growth of personalized medicine, technical advances in lung transplantation, and much more. Notable new content in the 6th edition includes discussion of the respiratory effects of vaping, detailed consideration of the idiopathic interstitial pneumonitides, state-of the-art discussion of lung nodules, a summary of the use of immunotherapy in the treatment of lung cancer, COVID-19-related lung disease and its management, and a comprehensive discussion of noninvasive ventilation, including its use in ambulatory and ICU settings. In addition, new chapters on cystic lung disease, lung cancer screening, the lung microbiome, developmental lung disorders, nocardiosis and actinomycosis, and application of ECMO are included.
This book provides a new mathematical theory for the treatment of an ample series of spatial problems of electrodynamics, particle physics, quantum mechanics and elasticity theory. This technique proves to be as powerful for solving the spatial problems of mathematical physics as complex analysis is for solving planar problems. The main analytic tool of the book, a non-harmonic version of hypercomplex analysis recently developed by the authors, is presented in detail. There are given applications of this theory to the boundary value problems of electrodynamics and elasticity theory as well as to the problem of quark confinement. A new approach to the linearization of special classes of the self-duality equation is also considered. Detailed proofs are given throughout. The book contains an extensive bibliography on closely related topics. This book will be of particular interest to academic and professional specialists and students in mathematics and physics who are interested in integral representations for partial differential equations. The book is self-contained and could be used as a main reference for special course seminars on the subject.
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