Models offer benefits even before they are put on line. Based on years of experience, the authors reveal in New Directions in Bioprocess Modeling and Control that significant improvements can result from the process knowledge and insight that are gained when building experimental and first-principle models for process monitoring and control. Doing modeling in the process development and early commercialization phases is advantageous because it increases process efficiency and provides ongoing opportunities for improving process control. This technology is important for maximizing benefits from analyzers and control tool investments. If you are a process design, quality control, information systems, or automation engineer in the biopharmaceutical, brewing, or bio-fuel industry, this handy resource will help you define, develop, and apply a virtual plant, model predictive control, first-principle models, neural networks, and multivariate statistical process control. The synergistic knowledge discovery on bench top or pilot plant scale can be ported to industrial scale processes. This learning process is consistent with the intent in the Process Analyzer and Process Control Tools sections of the FDA_s Guidance for Industry PAT _ A Framework for Innovative Pharmaceutical Development, Manufacturing and Quality Assurance. It states in the Process Analyzer section of the FDA_s guidance: _For certain applications, sensor-based measurements can provide a useful process signature that may be related to the underlying process steps or transformations. Based on the level of process understanding these signatures may also be useful for the process monitoring, control, and end point determination when these patterns or signatures relate to product and process quality._
Offering a state-of-the-art, authoritative summary of the most relevant scientific and clinical advances in the field, Principles and Practice of Movement Disorders provides the expert guidance you need to diagnose and manage the full range of these challenging conditions. Superb summary tables, a large video library, and a new, easy-to-navigate format help you find information quickly and apply it in your practice. Based on the authors' popular Aspen Course of Movement Disorders in conjunction with the International Parkinson and Movement Disorder Society, this 3rd Edition is an indispensable resource for movement disorder specialists, general neurologists, and neurology residents. - Explores all facets of movement disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. - Provides the essential information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. - Reflects recent advances in areas such as the genetics of Parkinsonian and other movement disorders, diagnostic brain imaging, new surgical approaches to patients with movement disorders, and new treatment guidelines for conditions such as restless legs syndrome. - Features a reader-friendly, full-color format, with plentiful diagrams, photographs, and tables. - Includes access to several hundred updated, professional-quality video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses.
Physics of Optoelectronics focuses on the properties of optical fields and their interaction with matter. Understanding that lasers, LEDs, and photodetectors clearly exemplify this interaction, the author begins with an introduction to lasers, LEDs, and the rate equations, then describes the emission and detection processes. The book summarizes and reviews the mathematical background of the quantum theory embodied in the Hilbert space. These concepts highlight the abstract form of the linear algebra for vectors and operators, supplying the "pictures" that make the subject more intuitive. A chapter on dynamics includes a brief review of the formalism for discrete sets of particles and continuous media. It also covers the quantum theory necessary for the study of optical fields, transitions, and semiconductor gain. This volume supplements the description of lasers and LEDs by examining the fundamental nature of the light that these devices produce. It includes an analysis of quantized electromagnetic fields and illustrates inherent quantum noise in terms of Poisson and sub-Poisson statistics. It explains matter-light interaction in terms of time-dependent perturbation theory and Fermi's golden rule, and concludes with a detailed discussion of semiconductor emitters and detectors.
Easy Access is the only handbook organized by the types of help student writers need. Part One (red tabs) provides a guide to writing processes and products. Solutions to common writing problems and ESL troublespots are found in Part Two (blue tab). Part Three (yellow tab) offers alphabetically organized definitions and examples of grammar, mechanics, and punctuation terms.
The definitive resource for designing and implementing evidence-based rehabilitation programs using therapeutic exercise Written and edited by top experts in their fields, Musculoskeletal Interventions provides the rehabilitation techniques, strategies, and considerations you need to effectively treat patients of all ages, abilities, and functional levels. With expanded coverage of movement systems, along with clinical pearls and hundreds of illustrations, this edition has been fully revised to reflect a contemporary movement system approach patient care. It focuses on the practical application of theory in a clinical setting, making it ideal for students and experienced physical therapists alike. Designed to make finding what you need quickly and easily, Musculoskeletal Interventions is organized into five sections: Foundations of the Rehabilitation Process Introduces the human movement system, the Guide to Physical Therapist Practice, and the clinical reasoning process Provides grounding on tissue healing, the Neuromuscular Scan Examination, pain, posture, and function Treating Physiologic Impairments During Rehabilitation Details general impairments that require attention throughout the rehabilitation process Covers muscle performance, endurance and aerobic capacity, mobility, range of motion, and neuromuscular control Tools of Rehabilitation Explains how to achieve optimal outcomes using various tools, including plyometric exercise, open- and closed-kinetic chain interventions, proprioceptive neuromuscular facilitation techniques, joint mobilization, postural stability and balance interventions, core stabilization training, aquatic therapy, functional movement screening, and more Interventions Strategies for Specific Regions Describes applications of techniques and interventions related to common movement-based, overuse, traumatic, and postoperative musculoskeletal dysfunction Provides guidance on conditions common to the shoulder complex, elbow, wrist, hand, digits, groin, hip, thigh, knee, lower leg, ankle, foot, and spine Discusses pathomechanics and injury mechanisms while focusing on rehabilitation strategies and concerns for specific injuries and providing example protocols Special Considerations for Specific Patient Populations Provides application of all previous intervention strategies and how these may need to be selected, adapted, and utilized for geriatric patients, pediatric patient, and physically active females Musculoskeletal Interventions is filled with features that help you understand and retain critical information. Learning aids include objectives, tales, clinical pearls, figures, video links, summary points, chapter-ending treatment guidelines, and references.
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