A real jewel of science history...brims with suspense and now-forgotten catastrophe and intrigue...Wadman’s smooth prose calmly spins a surpassingly complicated story into a real tour de force."—The New York Times “Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—Nature The epic and controversial story of a major breakthrough in cell biology that led to the conquest of rubella and other devastating diseases. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus--measles--on the rise today, no medical story could have more human drama, impact, or urgency than The Vaccine Race.
The sequel to Lead Me Not, this dangerously sexy second installment in the Twisted Love series continues Aubrey and Maxx’s love story, from New York Times bestselling author A. Meredith Walters—who “writes the most beautifully flawed characters that still have you swooning” (Sawyer Bennett, USA TODAY bestselling author of the Off series). Aubrey Duncan has loved…and lost. Should she follow a heart that’s betrayed her or a head that tells her to let go? Maxx Demelo’s addiction almost destroyed him. It ruined his life and, most importantly, his relationship with the only girl he ever loved. He has vowed to become the man Aubrey Duncan deserves. Even if he has to tear himself apart to do it. So he enters rehab, trying to fix the parts of him that are shattered as he longs to be healthy and whole. Aubrey lost everything because she chose to listen to her heart. Now she has sworn to put herself first, to heal in the only way that she can…far away from Maxx and his demons. But just as Aubrey is starting over, Maxx is released from rehab and thrust back into her world, determined to prove how much they still need each other. And the chaos that had defined them threatens to unleash once again… But a heart, no matter how broken, is impossible to ignore.
Reproduction of the original. The publishing house Megali specialises in reproducing historical works in large print to make reading easier for people with impaired vision.
This issue of Critical Care Nursing Clinics will include articles on the following topics: Non-invasive ventilation; Modes of mechanical ventilation; Mechanical ventilation effect on heart/lung interactions; Effect of ventilation on the lungs; VAP; Liberation/weaning & Sedation/pain control; Self/unplanned extubation; Communication; recovery and rehab post ICU; Airway protection with aging; home ventilation; monitoring of the mechanical vent patient; and Dyspnea.
An innovative analysis of Simone Forti's interdisciplinary art, viewing her influential 1960s “dance constructions” as negotiating the aesthetic strategies of John Cage and Anna Halprin. Simone Forti's art developed within the overlapping circles of New York City's advanced visual art, dance, and music of the early 1960s. Her “dance constructions” and related works of the 1960s were important for both visual art and dance of the era. Artists Robert Morris and Yvonne Rainer have both acknowledged her influence. Forti seems to have kept one foot inside visual art's frames of meaning and the other outside them. In Soft Is Fast, Meredith Morse adopts a new way to understand Forti's work, based in art historical analysis but drawing upon dance history and cultural studies and the history of American social thought. Morse argues that Forti introduced a form of direct encounter that departed radically from the spectatorship proposed by Minimalism, and prefigured the participatory art of recent decades. Morse shows that Forti's work negotiated John Cage's ideas of sound, score, and theater through the unique approach to movement, essentially improvisational and grounded in anatomical exploration, that she learned from performer and teacher Ann (later Anna) Halprin. Attentive to Robert Whitman's and La Monte Young's responses to Cage, Forti reshaped Cage's concepts into models that could accommodate Halprin's charged spaces and imagined, interpenetrative understanding of other bodies. Morse considers Forti's use of sound and her affective use of materials as central to her work; examines Forti's text pieces, little discussed in art historical literature; analyzes Huddle, considered one of Forti's signature works; and explicates Forti's later improvisational practice. Forti has been relatively overlooked by art historians, perhaps because of her work's central concern with modes of feeling and embodiment, unlike other art of the 1960s, which was characterized by strategies of depersonalization and affectlessness. Soft Is Fast corrects this critical oversight.
Geared to primary care practitioners, The Washington Manual® of Outpatient Internal Medicine focuses on common ambulatory medical problems encountered in each medical subspecialty. The book has a quick-reference format similar to The Washington Manual® of Medical Therapeutics, with a standard chapter template, a bulleted style, numerous tables and figures, and a two-color design. All chapters are written by house staff and faculty at Barnes-Jewish Hospital and Washington University School of Medicine. Coverage includes the traditional internal medicine subspecialties and other areas where problems are frequently seen in the ambulatory setting, such as dermatology, neurology, ophthalmology, otolaryngology, and psychiatry. Most subspecialties have separate symptom- and disease-based chapters. The Washington Manual® is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by LWW under license from Washington University.
Why do we often teach English poetic meter by the Greek terms iamb and trochee? How is our understanding of English meter influenced by the history of England's sense of itself in the nineteenth century? Not an old-fashioned approach to poetry, but a dynamic, contested, and inherently nontraditional field, "English meter" concerned issues of personal and national identity, class, education, patriotism, militarism, and the development of English literature as a discipline. The Rise and Fall of Meter tells the unknown story of English meter from the late eighteenth century until just after World War I. Uncovering a vast and unexplored archive in the history of poetics, Meredith Martin shows that the history of prosody is tied to the ways Victorian England argued about its national identity. Gerard Manley Hopkins, Coventry Patmore, and Robert Bridges used meter to negotiate their relationship to England and the English language; George Saintsbury, Matthew Arnold, and Henry Newbolt worried about the rise of one metrical model among multiple competitors. The pressure to conform to a stable model, however, produced reactionary misunderstandings of English meter and the culture it stood for. This unstable relationship to poetic form influenced the prose and poems of Robert Graves, Siegfried Sassoon, Wilfred Owen, W. B. Yeats, Ezra Pound, and Alice Meynell. A significant intervention in literary history, this book argues that our contemporary understanding of the rise of modernist poetic form was crucially bound to narratives of English national culture.
A comparative study of economic development policy, and its relationship with local power structures and cultural and social relations, in two Maryland towns that have rejected development.
Community economic development is conventionally explained using one of two models: a market model that assumes individuals always attempt to maximize their wealth, or a growth model that assumes land use is controlled by real estate developers who invariably pursue outside investment as a way of increasing land values and creating jobs and opportunities. In the first edition of Community, Culture, and Economic Development, Meredith Ramsay's close study of two small towns on Maryland's Lower Shore demonstrated that neither model can explain why these communities, alike in so many ways, responded so differently to economic decline or why archaic hierarchies of race, class, and gender remain deeply embedded and poverty seems nearly intractable. Ramsay showed how the lack of economic progress in Somerset, Maryland's poorest county, can best be explained by factoring history, culture, and social relations into the investigator's research. In this second edition she discusses changes that have taken place in the county since the early 1990s, including the dramatic legal victory of the "Somerset Six" and the Maryland ACLU, which ultimately paved the way for the election of an African American to a top county position for the first time in history.
Nikki Lee Manos' introduction draws upon a wide range of historical and critical texts, from John Stuart Mill's feminist tract of 1869 to Mary Poovey's contemporary theories about gender in Victorian fiction.".
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