Ten years ago, Bella Soroush's life was ruined by one of her pupils – Kane McCarthy. She has gradually rebuilt things – new school, new town, new friends – and finally feels at home in the depths of the countryside. Now Kane is back in her classroom, armed with relics of the past and claiming to want forgiveness. As the truths they've clung to begin to collapse, teacher and pupil are forced to confront their prejudices and the shared history that has bound them together.
Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.
Matthew Dennison's elegant and magisterial biography of Her late Majesty, updated following the death of Elizabeth II and the accession of King Charles III. 'A worthy and balanced overview of the Queen's life. Dennison is especially good on her childhood... quietly, tactfully, tastefully reverent.'The Times The death of Queen Elizabeth II on 8 September 2022 was more than just a moment of profound sadness; her passing marked the end of an era in our national life – and the final closing of the Elizabethan Age. For millions of people, both in Britain and across the world, Elizabeth II was the embodiment of monarchy. Her long life spanned nearly a century of national and global history, from a time before the Great Depression to the era of Covid-19. Her reign embraced all but seven years of Britain's postwar history up to the accession of her son King Charles III; she was served by fifteen UK prime ministers from Churchill to Truss, and witnessed the administrations of fourteen US presidents from Truman to Biden. In this brand-new biography of the longest-reigning sovereign in British history, Matthew Dennison traces her life and reign across an era of unprecedented and often seismic social change. Stylish in its writing and nuanced in its judgements, The Queen charts the joys and triumphs as well as the disappointments and vicissitudes of a remarkable royal life; it also assesses the achievement of a woman regarded as the champion of a handful of 'British' values endorsed – if no longer practised – by the bulk of the nation: service, duty, steadfastness, charity and stoicism.
This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.
Momentous events since September 11, 2001-Operation Enduring Freedom, the global war on terrorism, and the war in Iraq-have dramatically altered the political environment of the Muslim world. Many of the forces influencing this environment, however, are the products of trends that have been at work for many decades. This book examines the major dynamics that drive changes in the religio-political landscape of the Muslim world-a vast and diverse region that stretches from Western Africa through the Middle East to the Southern Philippines and includes Muslim communities and diasporas throughout the world-and draws the implications of these trends for global security and U.S. and Western interests. It presents a typology of ideological tendencies in the different regions of the Muslim world and identifies the factors that produce religious extremism and violence. It assesses key cleavages along sectarian, ethnic, regional, and national lines and examines how those cleavages generate challenges and opportunities for the United States. Finally, the authors identify possible strategies and political and military options for the United States to pursue in response to changing conditions in this critical and volatile part of the world.
In Mission Manifest, Matthew Shannon argues that American evangelicals were central to American-Iranian relations during the decades leading up to the 1979 revolution. These Presbyterian missionaries and other Americans with ideals worked with US government officials, nongovernmental organizations, and their Iranian counterparts as cultural and political brokers—the living sinews of a binational relationship during the Second World War and early Cold War. As US global hegemony peaked between the 1940s and the 1960s, the religious authority of the Presbyterian Mission merged with the material power of the American state to infuse US foreign relations with the messianic ideals of Christian evangelicalism. In Tehran, the missions of American evangelicals became manifest in the realms of religion, development programs, international education, and cultural associations. Americans who lived in Iran also returned to the United States to inform the growth of the national security state, higher education, and evangelical culture. The literal and figurative missions of American evangelicals in late Pahlavi Iran had consequences for the binational relationship, the global evangelical movement, and individual Americans and Iranians. Mission Manifest offers a history of living, breathing people who shared personal, professional, and political aims in Iran at the height of American global power.
An Introduction to Political Geography continues to provide a broad-based introduction to contemporary political geography for students following undergraduate degree courses in geography and related subjects. The text explores the full breadth of contemporary political geography, covering not only traditional concerns such as the state, geopolitics, electoral geography and nationalism; but also increasing important areas at the cutting-edge of political geography research including globalization, the geographies of regulation and governance, geographies of policy formulation and delivery, and themes at the intersection of political and cultural geography, including the politics of place consumption, landscapes of power, citizenship, identity politics and geographies of mobilization and resistance. This second edition builds on the strengths of the first. The main changes and enhancements are: four new chapters on: political geographies of globalization, geographies of empire, political geography and the environment and geopolitics and critical geopolitics significant updating and revision of the existing chapters to discuss key developments, drawing on recent academic contributions and political events new case studies, drawing on an increasing number of international and global examples additional boxes for key concepts and an enlarged glossary. As with the first edition, extensive use is made of case study examples, illustrations, explanatory boxes, guides to further reading and a glossary of key terms to present the material in an easily accessible manner. Through employment of these techniques this book introduces students to contributions from a range of social and political theories in the context of empirical case study examples. By providing a basic introduction to such concepts and pointing to pathways into more specialist material, this book serves both as a core text for first- and second- year courses in political geography, and as a resource alongside supplementary textbooks for more specialist third year courses.
Look into the eyes of these soldiers and see the faces of those who dared to stare into the face of Death. The Battle of Fredericksburg, fought December 11-15, 1862, is often remembered for the seemingly futile attacks by the Army of the Potomac against dug in Confederates on Marye's Heights. Less well understood is the fighting south of the heights on what has become known as Slaughter Pen Farm. In this work the images of thirty Union soldiers are published for the first time. They give a face and history to those men who struggled across that bloody landscape, as well as to those that charged up the slope of Marye's Heights into Confederate fire. Authors Matthew Borders and Joseph Stahl introduce you to these men, their stories and their sacrifice on the bullet swept battlefield of Fredericksburg.
Make the right decisions when it comes to pest control in agriculture! Bacillus thuringiensis: A Cornerstone of Modern Agriculture explores the impact that one of the most prominent biologically based pesticides has had on pest control technology—and the issues that surround its use. The book examines the development, use, and management of technologies derived from Bacillus thuringiensis (Bt), addressing the health, economic, environmental, and social concerns generated by the deployment of genetically engineered crops. Authors representing a diverse cross section of the international scientific community contribute review articles and research findings that address the use of Bt in microbial formulations and transgenic crops, technological advances in the genetic engineering of plants, advances in methodologies, and improved agricultural practices and productivity through the use of Bt cotton. Bacillus thuringiensis: A Cornerstone of Modern Agriculture examines the vital issues surrounding this Gram-positive bacterium. Contributors from academia, government, and industry address the safety of Bt for human consumption, its effects on non-target organisms, the role of microbial Bt products in crop production in the United States, and the utility and management of transgenic plants. The book also explores: engineering Bt transgenic rice for insect pest protection the Bt potato in developing countries Bt expression in sugarcane and cauliflower a comparative analysis of Bt cotton in Argentina the ecological impact, gene expression, and current resistance management requirements of Bt cotton in the United States and much more! Bacillus thuringiensis: A Cornerstone of Modern Agriculture is an essential resource for advanced students and technical specialists working in agriculture, biotechnology, entomology, pest management, and crop sciences. Stakeholders will also find it invaluable in regulatory decision making about genetically engineered crops, pesticide use, and crop protection.
Few areas of biomedical research provide greater opportunities to capitalize upon the revolution in genomics and molecular biology than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy in the Brain: From Bench to Bedside represents the definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped to create the field as well as those who are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects which would be of interest to anyone who is currently using or contemplating exploring gene therapy for neurobiological applications. Basic gene transfer technologies are discussed, with particular emphases upon novel vehicles, immunological issues and the role of gene therapy in stem cells. Numerous research applications are reviewed, particularly in complex fields such as behavioral neurobiology. Several preclinical areas are also covered which are likely to translate into clinical studies in the near future, including epilepsy, pain and amyotrophic lateral sclerosis. Among the most exciting advances in recent years has been the use of neurological gene therapy in human clinical trials, including Parkinson's disease, Canavan disease and Batten disease. Finally, readers will find "insider" information on technological and regulatory issues which can often limit effective translation of even the most promising idea into clinical use. This work provides up-to-date information and key insights into those gene therapy issues which are important to both scientists and clinicians focusing upon the brain and central nervous system.
Ten years ago, Bella Soroush's life was ruined by one of her pupils – Kane McCarthy. She has gradually rebuilt things – new school, new town, new friends – and finally feels at home in the depths of the countryside. Now Kane is back in her classroom, armed with relics of the past and claiming to want forgiveness. As the truths they've clung to begin to collapse, teacher and pupil are forced to confront their prejudices and the shared history that has bound them together.
. . . from expected death comes unexpected new life!" The Gospel of Matthew does not shy away from the realities of struggle, suffering, doubt, and death. Yet, from the first names in the genealogy to the last words spoken by Jesus, the Gospel testifies to the promise that from expected death comes unexpected new life. Through the actions of Tamar, Rahab, Ruth, and Bathsheba, we experience the expectation of death and the promise of unexpected new life. In the birth story of Jesus, Joseph suspects Mary of committing adultery. It is this dilemma that is the focus of the narrative. If he reveals her pregnancy, she could be killed. If he conceals her pregnancy, he will be going against the law of the Lord. What is a righteous man to do? In Joseph's dilemma, this experience of expected death, the Gospel of Matthew proclaims the promise of unexpected new life. The promise of unexpected new life is a theme that continues throughout Matthew's Gospel in the life and ministry of Jesus. The call of his disciples is a call from death to new life. The teaching of Jesus focuses on the experience of death and the promise of new life. In both healing and curing, Jesus brings unexpected new life to those who face death. But it is the death and resurrection of Jesus that is the climax of unexpected new life in the Gospel of Matthew. Even as Jesus experiences a most horrific and humiliating death in the crucifixion, death and the grave do not have the final say. In bearing witness to Jesus' resurrection, the Gospel of Matthew proclaims the magnificent promise of unexpected new life. Matthew J. Marohl invites you in these pages to read the Gospel of Matthew in a new way, from a fresh perspective. Integrating insights from the study of Mediterranean anthropology, Marohl makes the cultural world of the Gospel come alive, so that as you read Matthew again (or perhaps for the first time) you will certainly experience the powerful promise that from expected death comes unexpected new life!
Explore the tenderness and the tensions in the teachings of Jesus. The Gospel of Matthew portrays Jesus and his message as full of tender compassion and urgent warning. This six-part exploration of an enigmatic Gospel takes readers into the themes, topics, and tensions at the heart of Matthew's story about the life and work of Jesus. Chapters focus on blessing and comfort, judgment and retribution, the meaning of discipleship, Jesus’ vision for the Church and world, conflicts and complaints, and how the Gospel of Matthew speaks to believers today. The book can be read alone or used by small groups anytime throughout the year. Components include video teaching sessions featuring Matthew Skinner and a comprehensive Leader Guide.
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