A Choice Outstanding Academic Title, 2015 The first comprehensive history of modern American evangelicalism to appear in a generation, American Apocalypse shows how a group of radical Protestants, anticipating the end of the world, paradoxically transformed it. “The history Sutton assembles is rich, and the connections are startling.” —New Yorker “American Apocalypse relentlessly and impressively shows how evangelicals have interpreted almost every domestic or international crisis in relation to Christ’s return and his judgment upon the wicked...Sutton sees one of the most troubling aspects of evangelical influence in the spread of the apocalyptic outlook among Republican politicians with the rise of the Religious Right...American Apocalypse clearly shows just how popular evangelical apocalypticism has been and, during the Cold War, how the combination of odd belief and political power could produce a sleepless night or two.” —D. G. Hart, Wall Street Journal “American Apocalypse is the best history of American evangelicalism I’ve read in some time...If you want to understand why compromise has become a dirty word in the GOP today and how cultural politics is splitting the nation apart, American Apocalypse is an excellent place to start.” —Stephen Prothero, Bookforum
Negotiating is both an art and a science that requires specific knowledge and skills. Few school administrator preparation programs provide training in negotiating skills. As a result, when faced with the need to negotiate, most school administrators relyon the negotiating skills they have learned from other life experiences. While these strategies may work well when attempting to purchase a car, such skills often leave Individualized Education Plan meeting participants feeling dissatisfied, worn out, and alienated. This book prepares school administrators to successfully negotiate complex de.
Nearly every American Indian tribe has its own laws and courts. Taken together, these courts decide thousands of cases. Many span the full panoply of law—from criminal, civil, and probate cases, to divorce and environmental disputes.American Indian Tribal Law, now in its Second Edition, surveys the full spectrum of tribal justice systems. With cases, notes, and historical context, this text is ideal for courses on American Indian Law or Tribal Governments—and an essential orientation to legal practice within tribal jurisdictions. New to the Second Edition: A new chapter on professional responsibility and the regulation of lawyers in tribal jurisdictions Enhanced materials on Indian child welfare Additional materials on tribal laws that incorporate Indigenous language and culture Additional examples from tribal justice systems and practice Recent and noteworthy cases from tribal courts Professors and students will benefit from: A broad survey of dispute resolution systems within tribal jurisdictions A review of recent flashpoints in tribal law, such as internal tribal political matters, including intractable citizenship and election disputes enhanced criminal jurisdiction over nonmembers and non-Indians tribal constitutional reform, including a case study on the White Earth Nation Cases and material reflecting a wide range of American Indian tribes and legal issues Excerpts and commentary from a wellspring of current scholarship
Law and Society offers a contemporary overview of the structure and function of legal institutions, along with a lively discussion of criminal and civil law and their impact on society. Author Matthew Lippman draws on insights from over thirty years of teaching to develop an interdisciplinary approach that introduces students to both the influence of law on society and the influence of society on the law. Distinctive coverage of diversity, inequality, civil liberties, and globalism provides an incisive look at the intersection of theory and practice. The highly anticipated Third Edition includes updated discussions of issues facing today’s society, including inequality, international human rights, privacy and surveillance, and social control. Included with this title: The password-protected Instructor Resource Site (formally known as SAGE Edge) offers access to all text-specific resources, including a test bank and editable, chapter-specific PowerPoint® slides.
Beginning shortly after Charlemagne's death in 814, the inhabitants of his historical empire looked back upon his reign and saw in it an exemplar of Christian universality - Christendom. They mapped contemporary Christendom onto the past and so, during the ninth, tenth, and eleventh centuries, the borders of his empire grew with each retelling, almost always including the Christian East. Although the pull of Jerusalem on the West seems to have been strong during the eleventh century, it had a more limited effect on the Charlemagne legend. Instead, the legend grew during this period because of a peculiar fusion of ideas, carried forward from the ninth century but filtered through the social, cultural, and intellectual developments of the intervening years. Paradoxically, Charlemagne became less important to the Charlemagne legend. The legend became a story about the Frankish people, who believed they had held God's favour under Charlemagne and held out hope that they could one day reclaim their special place in sacred history. Indeed, popular versions of the Last Emperor legend, which spoke of a great ruler who would reunite Christendom in preparation for the last battle between good and evil, promised just this to the Franks. Ideas of empire, identity, and Christian religious violence were potent reagents. The mixture of these ideas could remind men of their Frankishness and move them, for example, to take up arms, march to the East, and reclaim their place as defenders of the faith during the First Crusade. An Empire of Memory uses the legend of Charlemagne, an often-overlooked current in early medieval thought, to look at how the contours of the relationship between East and West moved across centuries, particularly in the period leading up to the First Crusade.
As the world considers how to deal with the impacts of a changing climate, it’s vital that we understand the ways in which the United States’ policymaking process addresses environmental issues. A mix of existing theory and original analysis, Environmental Policymaking in an Era of Climate Change applies recent policy scholarship to questions of environmental governance, with a particular focus on climate change. The book examines how competing political actors influence policies within and across institutions, focusing on both a macro-level, where formal bodies set the agenda, and a meso-level, where issues are contained within policy subsystems. Divided into two sections, the book incorporates insights from political science and public policy to provide the reader with a better understanding of how environmental policy decisions are made. Part I offers a framework for understanding environmental policymaking, exploring the history of environmental policy, and discussing the importance of values in environmental policy. Part II applies the framework to the issue of climate change, focusing on agenda-setting and the role of formal institutions in the policymaking process, covering topics that include Congress, the Executive and Judicial branches, and how climate change cuts across policy subsystem boundaries. By placing specific climate change case studies in a broader context, Environmental Policymaking in an Era of Climate Change will help students enrolled in political science, public administration, public policy, and environmental studies courses – as well as all those interested in the impacts of policy on climate change – to understand what is, and will likely continue to be, one of the most pressing policy issues of our time.
Emphasising the contradictions of fandom, Matt Hills outlines how media fans have been conceptualised in cultural theory. Drawing on case studies of specific fan groups, from Elvis impersonators to X-Philes and Trekkers, Hills discusses a range of approaches to fandom, from the Frankfurt School to psychoanalytic readings, and asks whether the development of new media creates the possibility of new forms of fandom. Fan Cultures also explores the notion of "fan cults" or followings, considering how media fans perform the distinctions of 'cult' status.
Predestination has been the subject of perennial controversy among Christians, although in recent years theologians have shied away from it as a divisive and unedifying topic. In this book Matthew Levering argues that Christian theological reflection needs to continue to return to the topic of predestination, for two reasons: Firstly, predestinarian doctrine is taught in the New Testament. Reflecting the importance of the topic in many strands of Second Temple Judaism, the New Testament authors teach predestination in a manner that explains why Christian theologians continually recur to this topic. Secondly, the doctrine of predestination provides a way for Christian theologians to reflect upon two fundamental affirmations of biblical revelation. The first is God's love, without any deficiency or crimp, for each and every rational creature; the second is that God from eternity brings about the purpose for which he created us, and that he permits some rational creatures freely and permanently to rebel against his love. When theologians reflect on these two key biblical affirmations, they generally try to unite them in a logical synthesis. Instead, Levering argues, it is necessary to allow for the truth of each side of the mystery, without trying to blend the two affirmations into one. Levering pairs his discussion of Scripture with ecumenically oriented discussion of the doctrine of predestination in through the ages through the figures of Origen, Augustine, Boethius, John of Damascus, Eriugena, Aquinas, Ockham, Catherine of Siena, Calvin, Molina, Francis de Sales, Leibniz, Bulgakov, Barth, Maritain, and Balthasar. He concludes with a constructive chapter regarding the future of the doctrine.
Written by world renowned experts in surgical oncology, this book examines various types of cancer and their treatment options based on 'Level of Evidence' tables. The text provides an up-to-date review of the knowledge required by surgical oncologists, from basic biology, to the application of regional chemotherapy, minimally invasive surgery and palliative care.
In divided societies, representation in the police that empowers previously-marginalized groups reduces crime, builds trust, and improves citizen-state relations.
Germany, 1914-1933: Politics, Society and Culture takes a fresh and critical look at a crucial period in German history. Rather than starting with the traditional date of 1918, the book begins with the outbreak of the First World War in 1914, and argues that this was a pivotal turning point in shaping the future successes and failures of the Weimar Republic. Combining traditional political narrative with new insights provided by social and cultural history, the book reconsiders such key questions as: How widespread was support for the war in Germany between 1914 and 1918? How was the war viewed both ‘from above’, by leading generals, admirals and statesmen, and ‘from below’, by ordinary soldiers and civilians? What were the chief political, social, economic and cultural consequences of the war? In particular, did it result in a brutalisation of German society after 1918? How modern were German attitudes towards work, family, sex and leisure during the 1920s? What accounts for the extraordinary richness and experimentalism of this period? The book also provides a thorough and comprehensive discussion of the difficulties faced by the Weimar Republic in capturing the hearts and minds of the German people in the 1920s, and of the causes of its final demise in the early 1930s.
Become a machine learning pro! Google TensorFlow has become the darling of financial firms and research organizations, but the technology can be intimidating and the learning curve is steep. Luckily, TensorFlow For Dummies is here to offer you a friendly, easy-to-follow book on the subject. Inside, you’ll find out how to write applications with TensorFlow, while also grasping the concepts underlying machine learning—all without ever losing your cool! Machine learning has become ubiquitous in modern society, and its applications include language translation, robotics, handwriting analysis, financial prediction, and image recognition. TensorFlow is Google's preeminent toolset for machine learning, and this hands-on guide makes it easy to understand, even for those without a background in artificial intelligence. Install TensorFlow on your computer Learn the fundamentals of statistical regression and neural networks Visualize the machine learning process with TensorBoard Perform image recognition with convolutional neural networks (CNNs) Analyze sequential data with recurrent neural networks (RNNs) Execute TensorFlow on mobile devices and the Google Cloud Platform (GCP) If you’re a manager or software developer looking to use TensorFlow for machine learning, this is the book you’ll want to have close by.
Wrap your head around the complicated world of investment banking with this understandable and comprehensive resource The celebrated authors of Investment Banking For Dummies, 2nd Edition have updated and modernized their best-selling book to bring readers an invaluable and accessible volume about the investment banking industry. Written in the straightforward and approachable tone the For Dummies series is known for the world over, authors Matthew Krantz and Robert Johnson have created an indispensable resource for students and professionals new to investment banking. The book covers all the crucial topics required to understand the fundamentals of the industry, including: Strategies for different types of risk management: market, credit, operating, reputation, legal, and funding The key investment banking operations: venture capital, buyouts, M&A, equity underwriting, debt, and more The relationship between leverages buyout funds, hedge funds, and corporate and institutional clients Investment Banking For Dummies, 2nd Edition offers, for the first time, a brand-new chapter devoted to cryptocurrencies, and new content on “unicorn” IPOs, including Uber, Lyft, and Airbnb.
This book offers a comprehensive, biography-led examination of queenship in England between 850 and 1000, tracing the development of the queen’s role from bed companion to institutional office. The period 850–1000 is critical to the development of English queenship. In the aftermath of viking invasion, the kings of Wessex expanded their hegemony over neighbouring regions, gradually establishing themselves as the kings of England. Parallel to this broad narrative of political change is the lesser-known story, told in this book, of the royal women who took part in it. The lives of three remarkable women – Æthelflæd, Lady of the Mercians, and the West Saxon consorts Eadgifu and Ælfthryth – are central to the story, here retold through the careful analysis and reappraisal of source documents. These biographies set the stage for detailed study of the agency and advocacy of all women who held queenly office in England between 850 and 1000, as well as their legacies and reception by later generations. Early English Queens, 850–1000 gives important insights into the role women played in the first 150 years of the West Saxon dynasty, offering a compelling narrative that will appeal to students and scholars of early medieval England and royal studies.
From ancient Rome to the current Internet age, this sweeping history of ideas explores how different epochs wrestled with the issue of truth and lies. From the ancient Greeks and Romans to the modern era, how have people determined what is true? How have those with power and influence sought to control the narrative? Are we living in a post-truth era, or is that notion simply the latest attempt to control the narrative? The relationship between truth and power is the key theme. Moving through major historical periods, the author focuses on notable people and events, from well-known leaders like Julius Caesar and Adolf Hitler to lesser-known individuals like Procopius and Savonarola. He notes distinct parallels in history to current events. Julius Caesar's publication of his Gallic Wars and Civil Wars was an early exercise in political spin not unlike what we see today. During the English Civil War and the Enlightenment, pamphleteering coupled with the new power of the printing press challenged the status quo, as online and social media does in our time. And "fake news" was already being used by German chancellor Otto von Bismarck in nineteenth-century Europe and by the "yellow journalism" of American newspaper magnates William Randolph Hearst and Joseph Pulitzer near the turn of the twentieth century. The author concludes optimistically, noting that we are debating and discussing truth more fiercely today than in any previous era. The determination to arrive at the truth, despite the manipulations of the powerful, bodes well for the future of democracy.
At the close of the 19th century, strange new forms of energy arrested the American public's attention in ways that no scientific discovery ever had before. This groundbreaking cultural history tells the story of the first nuclear culture, one whose lasting effects would be seen in the familiar "atomic age" of the post-war twentieth century.
Forensic Psychology provides students with an in-depth and insightful introduction to the clinical practice of forensic psychology, the assessment and treatment of individuals who interact with the legal system. Focuses on the clinical practice of forensic psychology Integrates research, cases, and theory that provides students with a well-balanced picture of forensic psychology Incorporates two main themes, scope of practice and therapeutic jurisprudence, that focus on empirically supported clinical practice and expose students to case law and statutory law necessary in the practice of forensic psychology Utilizes real world examples and cases such as the impact of intelligence testing in the landmark Atkins vs. Virginia case that help students understand the practical role of forensic psychology Encourages an understanding of the law as a living and breathing entity, examining its ability to be therapeutic or anti-therapeutic for the people most directly affected by it Examines not only the criminal aspects of psychology and law but also civil aspects such as civil competence issues, sexual harassment claims, child custody evaluations, and personal injury cases which are often part of forensic practice Covers unique challenges that forensic psychologists often face clinically, legally, and ethically Instructor's Resources available at www.blackwellpublishing.com/huss.
2014 BMA Medical Book Awards Highly Commended in Radiology category! Image-Guided Interventions, a title in the Expert Radiology Series, brings you in-depth and advanced guidance on all of today?s imaging and procedural techniques. Whether you are a seasoned interventionalist or trainee, this single-volume medical reference book offers the up-to-the-minute therapeutic methods necessary to help you formulate the best treatment strategies for your patients. The combined knowledge of radiology experts from around the globe provides a broad range of treatment options and perspectives, equipping you to avoid complications and put today's best approaches to work in your practice. "... the authors and editors have succeeded in providing a book that is both useful, instructive and practical" Reviewed by RAD Magazine, March 2015 Formulate the best treatment plans for your patients with step-by-step instructions on important therapeutic radiology techniques, as well as discussions on equipment, contrast agents, pharmacologic agents, antiplatelet agents, and protocols. Make effective clinical decisions with the help of detailed protocols, classic signs, algorithms, and SIR guidelines. Make optimal use of the latest interventional radiology techniques with new chapters covering ablation involving microwave and irreversible electroporation; aortic endografts with fenestrated grafts and branch fenestrations; thoracic endografting (TEVAR); catheter-based cancer therapies involving drug-eluting beads; sacroiliac joint injections; bipedal lymphangiography; pediatric gastrostomy and gastrojejunostomy; and peripartum hemorrhage. Know what to look for and how to proceed with the aid of over 2,650 state-of-the-art images demonstrating interventional procedures, in addition to full-color illustrations emphasizing key anatomical structures and landmarks. Quickly reference the information you need through a functional organization highlighting indications and contraindications for interventional procedures, as well as tables listing the materials and instruments required for each. Access the fully searchable contents, online-only material, and all of the images online at Expert Consult.
Visually stunning and easy to use, this volume in the highly regarded Diagnostic Pathology series covers the normal histology of every organ system. This edition incorporates the most recent scientific and technological knowledge in the field to provide a comprehensive overview of all areas of normal histology, including introductory chapters on electron microscopy, immunofluorescence, immunohistochemistry and histochemistry, the cell, and the basic organization of tissues. With nearly 1,800 outstanding images, this reference is an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. Unparalleled visual coverage with carefully annotated photomicrographs, spectacular gross images, electron micrographs, and medical illustrations Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index Thoroughly updated content throughout, with all-new chapters on synovium and histologic artifacts, a thoroughly revised skeletal muscle chapter that now addresses normal histology in the setting of neuromuscular biopsy, and coverage of additional histologic variations that cause diagnostic confusion New content on immunohistochemistry; more image examples of newly recognized normal variations, mimics, and pitfalls; and expanded text in many sections for greater clarity and ease of reference
What is the place-if any-for violence in the Christian life? This book explores this question by analyzing a paradox of mainstream Christian history, theology, and ethics: At the heart of the Christian story, the suffering of violence stands as the price of faithfulness. From Jesus himself to martyrs who have died while following him, at the core of Christian faith is an experience of being victimized by the world's violence. At the same time, the majority opinion for most of Christian history has held that there are situations when the follower of Jesus may be justified in inflicting violence on others, especially in the context of war. Do these two facets of Christian ethics and experience-martyrdom and the just war-represent a contradiction, the self-defeating irony of those who follow a Lord who refused to defend himself taking up deadly weapons? In arguing that they do not, the book contends that any meaningful coherence between a theology of martyrdom and commitment to a just war ethic requires shifts away from a common heroic conception of Christian martyrdom and a common secularized Realpolitik conception of necessary violence. Instead, it requires a view of martyrdom that acknowledges even the martyrs as subject to the ambiguities of the human condition, even as they present a compelling witness to Jesus and the way of the cross. And it requires an approach to justified violence that reflects the self-sacrificial ethos of Jesus displayed in the lives of true Christian martyrs"--
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of normal histology of every organ system, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Normal Histology is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource. - Covers all areas of normal histology, including introductory chapters on electron microscopy, immunohistochemistry and histochemistry, the cell, and the basic organization of tissues - Includes important updates throughout, covering not only traditional normal histology, but also its morphologic spectrum (variant normal histology) as well as recent advances in immunohistochemistry that expand the spectrum of antigen expression in normal tissues - Contains new images in over 50% of the chapters, including images of the most common abnormal findings in each organ system, helping provide direct contrast with adjacent normal histology (i.e., what is normal and what is not) - Provides the at-a-glance information necessary for diagnosis or adequacy evaluation at the time of procedure, using a concise, synoptic writing style - Features more than 2,100 print and online images, including carefully annotated photomicrographs, gross images, electron micrographs, and full-color medical illustrations to help practicing and in-training pathologists reach a confident diagnosis - Employs consistently templated chapters, bulleted content, key facts, a variety of test data tables, annotated images, and an extensive index for quick, expert reference at the point of care - An eBook version is included with purchase. Giving you the power to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
While the fate of minorities under Nazism is well known, the earlier expulsions of Germany's unwanted residents are less well understood. Against a backdrop of raging public debate, and numerous claims of a 'state of exception', tens of thousands of vulnerable people living in the German Empire were the victims of mass expulsion orders between 1871 and 1914. Groups as diverse as Socialists, Jesuits, Danes, colonial subjects, French nationalists, Poles, and 'Gypsies' were all removed, under circumstances that varied from police actions undertaken by provincial governors through to laws authorising removals passed by the Reichstag. Purging the Empire examines the competing voices demanding the removal or the preservation of suspect communities, suggesting that these expulsions were enabled by the decentralised and participatory nature of German politics. In a surprisingly responsive political system, a range of players, including the Kaiser, the Reichstag, the bureaucracy, provincial officials, and local police authorities were all empowered to authorise the expulsion of unwanted residents. Added to this, the German press, civic associations, chambers of commerce, public intellectuals, religious societies, and the grassroots membership of political parties all played an important role in advocating or denouncing the measures before, during and after their implementation. Far from revealing the centrality of authoritarian caprice, Germany's mass expulsions point to the diffuse nature of coercive sovereign power and the role of public pressure in authorising or censuring the removals that took place in a modern, increasingly parliamentary Rechtsstaat.
Policy change is not predictable from election results or public opinion. The amount, issue content, and ideological direction of policy depend on the joint actions of policy entrepreneurs, especially presidents, legislators, and interest groups. This makes policymaking in each issue area and time period distinct and undermines unchanging models of policymaking.
Companion volume to Cinemeducation Volume 1 Cinemeducation, Volume 2 outlines a comprehensive approach to using film in graduate and medical education. It provides readers with a wide array of film excerpts ready for immediate application in the classroom. Each excerpt includes the counter time, year of release, names of actors, a short description of the movie and the scene being highlighted as well as discussion questions. Entire chapters are dedicated to reality television, mainstream television, music videos, documentaries and YouTube. Clearly structured, this second volume dives deep into human experiences. Authors from five continents have composed 49 chapters devoted to a wide assortment of new topics relevant to medical and postgraduate healthcare education. Some of the specific issues covered include substance abuse, gambling, dealing with tragedy, diabetes, heart disease, chronic illness and obstetrics as well as mental health problems. Some films portray health care professionals both positively and negatively and these are presented with rich detail. A wide variety of specialties and different health careers are covered. All of these areas converge on the common ground of compassion in the medical experience. This book is ideal for the undergraduate or postgraduate classroom. All healthcare educators will appreciate its comprehensive scope and innovative approach, including those in psychology, social services, dentistry and veterinary science.
In an era when technology, biology & culture are becoming ever more closely connected, 'The Dada Cyborg' explains how the cyborg as we know it today developed between 1918 & 1933 as German artists gave visual form to their utopian hopes & fantasies in a fearful response to World War I.
Now in full color, the #1 text spanning the fields of public health and preventive medicine brings you fully up to date on the issues and topics you need to know A Doody's Core Title for 2023! Maxcy-Rosenau-Last Public Health and Preventive Medicine has been updated and revised for the first time in more than a decade. This highly anticipated and extensive edition provides the most current information and insights available on evidence-based public health and preventive medicine, from basic methodologies of public health to principles of epidemiology and infection control to environmental toxicology to global health. The most comprehensive resource of its kind, Maxcy-Rosenau-Last Public Health and Preventive Medicine is the clear choice for anyone seeking a career in public health. Features: • Edited and written by a who's who of global experts • 384 photos and illustrations • New full-color format and improved artwork • Significantly expanded coverage of diseases and preventive methods common in international markets • Greater use of tables and summary lists for easier reading and retention
Web surfers find their PC-side companion with this updated guide to resources, techniques and contacts for their favorite hobbies and interests. Contains updated coverage of how to get started, how to do searches, sending email, getting a home page, and more.
How the attorney-client relationship favors the privileged in criminal court—and denies justice to the poor and to working-class people of color The number of Americans arrested, brought to court, and incarcerated has skyrocketed in recent decades. Criminal defendants come from all races and economic walks of life, but they experience punishment in vastly different ways. Privilege and Punishment examines how racial and class inequalities are embedded in the attorney-client relationship, providing a devastating portrait of inequality and injustice within and beyond the criminal courts. Matthew Clair conducted extensive fieldwork in the Boston court system, attending criminal hearings and interviewing defendants, lawyers, judges, police officers, and probation officers. In this eye-opening book, he uncovers how privilege and inequality play out in criminal court interactions. When disadvantaged defendants try to learn their legal rights and advocate for themselves, lawyers and judges often silence, coerce, and punish them. Privileged defendants, who are more likely to trust their defense attorneys, delegate authority to their lawyers, defer to judges, and are rewarded for their compliance. Clair shows how attempts to exercise legal rights often backfire on the poor and on working-class people of color, and how effective legal representation alone is no guarantee of justice. Superbly written and powerfully argued, Privilege and Punishment draws needed attention to the injustices that are perpetuated by the attorney-client relationship in today’s criminal courts, and describes the reforms needed to correct them.
The Leading Introduction to Biochemical and Bioprocess Engineering, Updated with Key Advances in Productivity, Innovation, and Safety Bioprocess Engineering, Third Edition, is an extensive update of the world’s leading introductory textbook on biochemical and bioprocess engineering and reflects key advances in productivity, innovation, and safety. The authors review relevant fundamentals of biochemistry, microbiology, and molecular biology, including enzymes, cell functions and growth, major metabolic pathways, alteration of cellular information, and other key topics. They then introduce evolving biological tools for manipulating cell biology more effectively and to reduce costs of bioprocesses. This edition presents major advances in the production of biologicals; highly productive techniques for making heterologous proteins; new commercial applications for both animal and plant cell cultures; key improvements in recombinant DNA microbe engineering; techniques for more consistent authentic post-translational processing of proteins; and other advanced topics. It includes new, improved, or expanded coverage of The role of small RNAs as regulators Transcription, translation, regulation, and differences between prokaryotes and eukaryotes Cell-free processes, metabolic engineering, and protein engineering Biofuels and energy, including coordinated enzyme systems, mixed-inhibition and enzyme-activation kinetics, and two-phase enzymatic reactions Synthetic biology The growing role of genomics and epigenomics Population balances and the Gompetz equation for batch growth and product formation Microreactors for scale-up/scale-down, including rapid scale-up of vaccine production The development of single-use technology in bioprocesses Stem cell technology and utilization Use of microfabrication, nanobiotechnology, and 3D printing techniques Advances in animal and plant cell biotechnology The text makes extensive use of illustrations, examples, and problems, and contains references for further reading as well as a detailed appendix describing traditional bioprocesses. Register your product at informit.com/register for convenient access to downloads, updates, and corrections as they become available.
For western colonists in the early American backcountry, disputes often ended in bloodshed and death. Making the Frontier Man examines early life and the origins of lawless behavior in Pennsylvania, Virginia, Kentucky, and Ohio from 1750 to 1815. It provides a key to understanding why the trans-Appalachian West was prone to violent struggles, especially between white men. Traumatic experiences of the Revolution and the Forty Years War legitimized killing as a means of self-defense—of property, reputation, and rights—transferring power from the county courts to the ordinary citizen. Backcountry men waged war against American Indians in state-sponsored militias as they worked to establish farms and seize property in the West. And white neighbors declared war on each other, often taking extreme measures to resolve petty disputes that ended with infamous family feuds. Making the Frontier Man focuses on these experiences of western expansion and how they influenced American culture and society, specifically the nature of western manhood, which radically transformed in the North American environment. In search of independence and improvement, the new American man was also destitute, frustrated by the economic and political power of his elite counterparts, and undermined by failure. He was aggressive, misogynistic, racist, and violent, and looked to reclaim his dominance and masculinity by any means necessary.
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