Matthew J Killeen's Books

Cardiac Drug Safety: A Bench To Bedside Approach

By: Matthew J Killeen

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Cardiac Drug Safety: A Bench To Bedside Approach

By: Matthew J Killeen

Ensuring the safety of new medical products remains a major challenge for the pharmaceutical industry. Cardiac safety, particularly drug-induced heart rhythm abnormalities, remains an important cause of pipeline attrition and has resulted in countless major product recalls or label changes. The risk of encountering this major adverse event continues to shape the drug development and regulatory landscape.Extensive research over the past decade has shed light on the root causes of arrhythmias that are triggered by medications and has helped drive, and optimize, drug safety testing. However, current cardiac safety platforms have several limitations and there remains a pressing unmet need to improve the predictive power of today's drug safety tests.Fundamental to addressing the problem of drug-induced arrhythmias, and to reducing the impact of this safety signal on drug development, is a complete understanding of how these events may arise, what cardiac safety tests are currently used, and what opportunities there are to enhance patient safety and reduce the risk of detecting cardiac toxicity in later stages of product commercialization. By introducing the reader to these core concepts, this book delivers key insight into the increasingly important and dynamic field of cardiac safety.

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Page Count

189

Publisher

World Scientific

Published Date

ISBN 10

9814464406

ISBN 13

9789814464406

Building Fjords in the Great Deserts

Combining Forgotten Lands and Forgotten People to Defeat Ancient Climate Change

By: James Michael Matthew

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Building Fjords in the Great Deserts

Combining Forgotten Lands and Forgotten People to Defeat Ancient Climate Change

By: James Michael Matthew

After the United Nations held its 2023 Climate Change Conference, it became vogue to label the fossil fuels industry as “the elephant in the room.” But it’s really just the tiny baby elephant. The real elephant in the room – the one that no one wants to acknowledge let alone talk about – is that net zero carbon and sustainability will never work to defeat climate change. It’s also not practical, as it would result in the destruction of economies and force people to live lives they do not want to live. Even if it could be achieved, it would not fix rising ocean coastlines, biodiversity loss, desertification, and climate change. James Michael Matthew, the founder and chairman of JM Prophecies Corp. and the author of numerous books on how to defeat climate change, proposes the perfect solution in this book: building fjords in the great deserts. His plan to defeat climate change begins with pumping ocean water into salt basins that already exist in deserts and arid regions around the world. Consider what’s at stake and find out how the author’s strategy could be implemented step by step in this groundbreaking work.

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Page Count

135

Publisher

Archway Publishing

Published Date

ISBN 10

166576001X

ISBN 13

9781665760010

Fusion's Promise

How Technological Breakthroughs in Nuclear Fusion Can Conquer Climate Change on Earth (And Carry Humans To Mars, Too)

By: Matthew Moynihan,Alfred B. Bortz

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Fusion's Promise

How Technological Breakthroughs in Nuclear Fusion Can Conquer Climate Change on Earth (And Carry Humans To Mars, Too)

By: Matthew Moynihan,Alfred B. Bortz

For over 60 years, scientists and engineers have been trying to crack a seemingly intractable problem: how to build practical devices that exploit nuclear fusion. Access to electricity has facilitated a standard of living that was previously unimaginable, but as the world’s population grows and developing nations increasingly reap the benefits of electrification, we face a serious global problem: burning fossil fuels currently produces about eighty percent of the world's energy, but it produces a greenhouse effect that traps outgoing infrared radiation and warms the planet, risking dire environmental consequences unless we reduce our fossil fuel consumption to near zero in the coming decades. Nuclear fusion, the energy-producing process in the sun and stars, could provide the answer: if it can be successfully harnessed here on Earth, it will produce electricity with near-zero CO2 byproduct by using the nuclei in water as its main fuel. The principles behind fusion are understood, but the technology is far from being fully realized, and governments, universities, and venture capitalists are pumping vast amounts of money into many ideas, some highly speculative, that could lead to functioning fusion reactors. This book puts all of these attempts together in one place, providing clear explanations for readers who are interested in new energy technologies, including those with no formal training in science or engineering. For each of the many approaches to fusion, the reader will learn who pioneered the approach, how the concept works in plain English, how experimental tests were engineered, the future prospects, and comparison with other approaches. From long-established fusion technologies to emerging and exotic methods, the reader will learn all about the idea that could eventually constitute the single greatest engineering advance in human history.

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Page Count

285

Publisher

Springer Nature

Published Date

ISBN 10

3031229061

ISBN 13

9783031229060

Cardiac Drug Safety: A Bench To Bedside Approach

By: Matthew J Killeen

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Cardiac Drug Safety: A Bench To Bedside Approach

By: Matthew J Killeen

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

189

Publisher

World Scientific

Published Date

ISBN 10

9814464406

ISBN 13

9789814464406

Book's by Matthew J Killeen

Cardiac Drug Safety: A Bench To Bedside Approach

Cardiac Drug Safety: A Bench To Bedside Approach

Building Fjords in the Great Deserts

Building Fjords in the Great Deserts

Fusion's Promise

Fusion's Promise

Cardiac Drug Safety: A Bench To Bedside Approach

Cardiac Drug Safety: A Bench To Bedside Approach

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