This book is designed to assist physicians in the everyday management of hypertensive patients, with a particular focus on difficult-to-treat and resistant hypertension. The selected clinical cases are representative of the patients who are seen in the “real world”, rather than rare clinical cases, and provide examples of management according to current international guidelines. The scenarios considered include not only cases in which arterial hypertension is truly resistant but also instances of pseudo-resistant hypertension, including cases in which resistance is related to comorbidities, concomitant treatments, or the use of drugs. The ultimate objective is to provide paradigmatic examples of evidence-based approaches to difficult-to-treat patients that will help physicians to select the most appropriate diagnostic tools and evidence-based treatment strategy for each individual patient.
Between 1608 and 1610 the canopy of the night sky was ripped open by an object created almost by accident: a cylinder with lenses at both ends. Galileo’s Telescope tells how this ingenious device evolved into a precision instrument that would transcend the limits of human vision and transform humanity’s view of its place in the cosmos.
Artillery survey suffered during the pacifist inter-war period but the war in North Africa highlighted its importance. By the end of 1942 ten major survey units had been formed. Nine were conventional serving in all the main theatres, including the Far East. They played a key part in victories such as El Alamein, Anzio, Caen and Imphal, with their flash-spotting, sound-ranging and surveying of gun lines. A tenth regiment was secretly involved tracing the flight of Hitlers V1 and V2 rockets in order to locate their launch bases. These ‘soldier-scientists were all trained at the School of Survey, Larkhill, on Salisbury Plain. Their work took them to the front line and a considerable number were casualties or became POWs. This is the story of the contribution of these 4,000 men who made up the Survey Regiments. It tells of the heroes, such as Robert (Tug) Wilson of the SBS and the skilful men whose actions under the most difficult and dangerous conditions have received little acknowledgement until now.
Valerio Massimo Manfredi's The Ancient Curse is a thrilling archaeological mystery with a supernatural twist. In the darkest hours of the night at the Museum of Volterra, young archaeologist Fabrizio Castellani is immersed in his work. He has discovered that the famous Etruscan statue known as the 'shade of twilight' contains a mysterious object, seemingly enclosed within the sculpture itself. He is suddenly interrupted by the phone ringing – on the other end of the line an icy female voice warns him to abandon his research at once. A series of gruesome killings follow. The victims, who have all been involved in the desecration of an unexplored tomb, seem to have been torn to pieces by a beast of unimaginable size. Meanwhile, as Fabrizio excavates the Etruscan tomb he discovers something extraordinary, and chilling . . . Will Fabrizio manage to unravel these secrets without being sucked into the spiral of violence himself?
This book is designed to assist physicians in the everyday management of hypertensive patients, with a particular focus on difficult-to-treat and resistant hypertension. The selected clinical cases are representative of the patients who are seen in the “real world”, rather than rare clinical cases, and provide examples of management according to current international guidelines. The scenarios considered include not only cases in which arterial hypertension is truly resistant but also instances of pseudo-resistant hypertension, including cases in which resistance is related to comorbidities, concomitant treatments, or the use of drugs. The ultimate objective is to provide paradigmatic examples of evidence-based approaches to difficult-to-treat patients that will help physicians to select the most appropriate diagnostic tools and evidence-based treatment strategy for each individual patient.
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