Masatoshi Nei's Books

Mutation-Driven Evolution

By: Masatoshi Nei

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The purpose of this book is to present a new theory of mutation-driven evolution, which is based on recent advances in genomics and evolutionary developmental biology. This theory asserts that the driving force of evolution is mutation and natural selection is of secondary importance.

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Page Count

261

Publisher

OUP Oxford

Published Date

ISBN 10

0199661731

ISBN 13

9780199661732

Mutation-Driven Evolution

By: Masatoshi Nei

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Mutation-Driven Evolution

By: Masatoshi Nei

The purpose of this book is to present a new mechanistic theory of mutation-driven evolution based on recent advances in genomics and evolutionary developmental biology. The theory asserts, perhaps somewhat controversially, that the driving force behind evolution is mutation, with natural selection being of only secondary importance. The word 'mutation' is used to describe any kind of change in DNA such as nucleotide substitution, gene duplication/deletion, chromosomal change, and genome duplication. A brief history of the principal evolutionary theories (Darwinism, mutationism, neo-Darwinism, and neo-mutationism) that preceded the theory of mutation-driven evolution is also presented in the context of the last 150 years of research. However, the core of the book is concerned with recent studies of genomics and the molecular basis of phenotypic evolution, and their relevance to mutation-driven evolution. In contrast to neo-Darwinism, mutation-driven evolution is capable of explaining real examples of evolution such as the evolution of olfactory receptors, sex-determination in animals, and the general scheme of hybrid sterility. In this sense the theory proposed is more realistic than its predecessors, and gives a more logical explanation of various evolutionary events. Mutation-Driven Evolution is suitable for graduate level students as well as professional researchers (both empiricists and theoreticians) in the fields of molecular evolution and population genetics. It assumes that the readers are acquainted with basic knowledge of genetics and molecular biology.

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Page Count

605

Publisher

OUP Oxford

Published Date

ISBN 10

0191637823

ISBN 13

9780191637827

Molecular Evolution and Phylogenetics

By: Masatoshi Nei,Sudhir Kumar

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Molecular Evolution and Phylogenetics

By: Masatoshi Nei,Sudhir Kumar

During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.

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Page Count

444

Publisher

Oxford University Press

Published Date

ISBN 10

0199881227

ISBN 13

9780199881222

Molecular Evolutionary Genetics

By: Masatoshi Nei

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Molecular Evolutionary Genetics

By: Masatoshi Nei

-- "The Scientist

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Page Count

526

Publisher

Columbia University Press

Published Date

ISBN 10

0231063210

ISBN 13

9780231063210

Molecular Evolution and Phylogenetics

By: Masatoshi Nei,Sudhir Kumar

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Molecular Evolution and Phylogenetics

By: Masatoshi Nei,Sudhir Kumar

This is a treatment of the statistical methods used in molecular evolution and phylogenetics study. Newly developed statistical methods for studying the molecular clock, adaptive evolution and inference of ancestral amino acid sequences are also included.

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Page Count

356

Publisher

Oxford University Press, USA

Published Date

ISBN 10

0195135857

ISBN 13

9780195135855

Book's by Masatoshi Nei

Mutation-Driven Evolution

Mutation-Driven Evolution

Mutation-Driven Evolution

Mutation-Driven Evolution

Molecular Evolution and Phylogenetics

Molecular Evolution and Phylogenetics

Molecular Evolutionary Genetics

Molecular Evolutionary Genetics

Molecular Evolution and Phylogenetics

Molecular Evolution and Phylogenetics

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