Neurogenesis, or the birth of new neuronal cells, was thought to occur only in developing organisms. However, recent research has demonstrated that neurogenesis does indeed continue into and throughout adult life. On going neurogenesis is thought to be an important mechanism underlying neuronal plasticity, enabling organisms to adapt to environmental changes and influencing learning and memory throughout life. A number of different factors that regulate neurogenesis have been identified. Physicial activity and environmental conditions have been known to affect proliferation and survival of neurons. Hormones have also been found to influence the rate of neurogenesis in vertebrates (e.g. testosterone) and invertebrates (eg: ecdysone). Serotonin is believed to play a key role in neurogenesis.
The healthcare system is experiencing unprecedented challenges and opportunities that will revolutionize the sector. The rising demand for health services and the resources restrictions have put increased pressure on healthcare organizations to improve cost-efficiency and service offerings. The pandemic has further exacerbated the main pressure points of the healthcare sector. Currently, the shift towards patient centricity is gaining momentum, therefore there is a need to rethink how health systems can embrace this concept, in particular with digitization, service innovation and value co-creation. Focusing on digital healthcare, this book proposes a theoretical framework, along with managerial implications, on moving towards a patient-centric model. It explores the role of digitization and innovation in solving existing challenges in the sector, and includes the concept of 'One Digital Health', which refers to global health and transformation and recognizes the importance of the connection between humans, animals, nature and the interrelation of different health systems. With clear implications to Sustainable Development Goal 3: ‘Ensure healthy lives and promote wellbeing for all at all ages,’ the authors argue that innovative transformation in the sector can support the Agenda 2030.
Insurance intermediaries can help consumers to economize on information and transaction costs in insurance markets. This book analyzes conduct and performance in the market for insurance information services by applying search theoretical and industrial organization approaches. Based on a sample of 927 insurance intermediaries, coverage empirically studies the factors that affect the quality of the information services provided by them.
Climate change has had a significant impact globally, predominantly for those vulnerable to its influence. The first book of its kind, The Climate Resilient Organization assesses the issues that have mounted for decision-makers in the field, while prov
Bernardo Bellotto is considered to be one of the greatest topographical and landscape painters of the eighteenth century. Trained as a painter of cityscapes, he produced vivid and memorable images of many of the greatest cities of Europe, including Venice, Florence, Rome, Dresden, Munich, Vienna, and Warsaw. He also ventured successfully into genre, portraiture, allegory, and history painting. This beautiful book, written by leading specialists on Bellotto, examines his career and artistic development, places his work in the context of the political needs of central European monarchs, and presents a selection of his major paintings from each of his principal periods and genres. Bellotto began as a painter of conventional views of Venice in the manner of his more famous uncle, Canaletto. However, his quest for new subject matter led him to visit half a dozen cities in northern and central Italy in the early 1740s, and at twenty-five he left Italy for northern Europe, where he spent the rest of his life working for royal and aristocratic patrons. In Dresden he was engaged in the service of Augustus III, where he created many glorious canvases and was awarded the title of Court Painter. He then moved to Vienna and recorded its attractions for Empress Maria Theresa. He ended his career as Court Painter in Warsaw, and his detailed paintings of the city played an important role in its reconstruction after the Second World War. The book demonstrates that in each of the places Bellotto lived, he was able to capture the particular light and life with sensitivity and imagination.
F. Scott Fitzgerald on Silent Film is the first full-length monograph focusing on the silent movie adaptations of the celebrated author’s work. This ground-breaking book reveals the crucial role that Hollywood played in establishing Fitzgerald’s burgeoning reputation in the 1920s.
Computational immunology offers in silico strategies for understanding of complex processes occurring in the natural immune system of a living organism that are difficult to explore by traditional in vivo or in vitro techniques. The monograph introduces conceptual languages and approaches for modelling biological processes. The Agent Modelling Language is investigated for conceptualisation of immune processes. AML-based diagrams represent properties and processes occurring in a lymph node.
Psychoneuroendocrinology is the clinical study of hormone fluctuations and their relationship to human behaviour. It may be viewed from the perspective of psychiatry, where in certain mood disorders, there are associated neuroendocrine or hormonal changes. It may also be viewed from the perspective of endocrinology, where certain endocrine disorders can be associated with psychiatric illness. It is the blend of psychiatry and endocrinology. This new book presents the latest research advances in the field.
The COVID-19 pandemic and the subsequent need for policy support have called the traditional separation between fiscal and monetary policies into question. Based on simulations of an open economy DSGE model calibrated to emerging and advance economies and case study evidence, the analysis shows when constraints are binding a more integrated approach of looking at policies can lead to a better policy mix and ultimately better macroeconomic outcomes under certain circumstances. Nonetheless, such an approach entails risks, necessitating a clear assessment of each country’s circumstances as well as safeguards to protect the credibility of the existing institutional framework.
Putting forward a comprehensive view of knowledge with a specific perspective on place and space, this book provides a new perspective on the globalisation of knowledge. Crossing disciplinary boundaries, the principal agenda of this volume is to open up a perspective ’beyond knowledge’ - i.e. beyond the interpretation of knowledge as scientific-technical knowledge. Author Martina Fuchs introduces further kinds of knowledge and interpretation which influence managements’ perception of globalisation and therefore the knowledge which is going global. She refers to knowledge in the sense of experiences, competencies in the production and labour process, as well as mutually shared mental constructs which are embedded in a context of understanding and interpretation. Exploring beyond the meaning of worldwide knowledge as general open access knowledge, this book also discusses barriers to knowledge, problems of transfer, and the influence of governance and control.
This book traces the evolution of biotechnology from prehistoric organismal manipulation by our first settled ancestors through to speculation about future directions for the technology as it increasingly intersects with other high technologies such as IT and Nanotech. The trajectory is demonstrated by various events throughout history that have intersected or built on one another to lead to the forward progression of a technology.
Seminar paper from the year 2003 in the subject English Language and Literature Studies - Linguistics, grade: 2+ (B), University of Duisburg-Essen (Anglistics), course: Hauptseminar: Aspects of the history of English, language: English, abstract: In this work I examine the history of the English language - especially the Middle English period throughout Geoffrey Chaucer. I also want to show how English has developed over the years and how it has been influenced. After the general view on Chaucer’s life and influences I try to give an overview of several aspects of the English language at this time. But I have to say that I can not go too far in detail in some points because there are too much facts which have influenced the English language. At last I close with a short view about the Early-Modern-English period.
An insight into PES policies and practices. Public Employment Services are confronted with the ever-changing world of work from various angles: as organisation, as employer and as key actor on the labour market. Decisive mega trends such as globalisation, demographic shifts or migration, driven by tremendous technological developments and characterised by a considerable extent of complexity and volatility, have a huge impact on our labour markets and finally on PES. Guiding citizens through this (r)evolution and supporting them to manage necessary or desired transitions is a shared challenge of European PES and a huge public responsibility PES are actively taking up. Thereby PES are contributing to well-balanced labour markets which are essential for sustainable growth and for maintaining our social welfare supporting systems. PES jointly develop solutions through exchanging and learning from each other, rethinking practices and policies and continuously improving their organisations for more sustainable and inclusive labour markets and in order to better serve employers and jobseekers. This book gives an insight into PES policies and practices which are inspired by the close collaboration in the PES Network. PES Network members reflect on their European-wide learning organisation, they point out challenges and their strategic and operational answers from a national perspective, bringing in valuable personal experience. “PES Policies and Practices” thus touches upon a broad variety of PES core topics and gives you the chance to understand their business in a politically shaped environment, characterised by a unique collaboration. The collection of voices from the PES Network world in this book demonstrates the Network ́s potential to anticipate and respond to changes in the world of work. EXTRACT What is Benchlearning about? How do other Public Employment Services (PES) solve problems? What is the secret of their success? Can I learn from the others and transfer successful practices? PES try to find answers on these questions through “Benchlearning”. Comparing performance, benchmarking, was the main subject of the initial discussions in the Network of Heads of PES going back to the 1998s. Over time, the focus moved to mutual learning and the exchange of good practices across Europe. Benchlearning combines these two main elements. It is about interlinking benchmarking and mutual learning. In more detail: The PES Network Decision defines Benchlearning as “process of creating a systematic and integrated link between benchmarking and mutual learning activities that consists of identifying good performances through indicator-based benchmarking systems [...] and of using findings for tangible and evidence-informed mutual learning activities, including good or best practice models”. ABOUT AUTHORS Fons Leroy was the chief executive officer of VDAB, the Flemish Public Employment Service, and current Chair of the European Network of Public Employment Services. Lenka Kint was from 2011 to 2017 Executive Sercetary at WAPES, the World Association of Public Employment Services, and is currently Strategic accountmanager International Relations at VDAB. Martina Winkler is a Seconded National Expert from the German Federal Employment Agency to the EU Commission, working in the PES Network Secretariat on the Benchlearning initiative.
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