“Breathless, marvelous . . . Latin American fiction at its pulpy, phantasmagorical finest . . . A literary masterpiece masquerading as a police procedural.” —Junot Diaz When a young journalist named Bernardo Blanco is killed in the fictional Mexican port city of Paracuán, investigation into his murder reveals missing links in a disturbing multiple homicide case from twenty years earlier. As police officer Ramón “el Macetón” Cabrera discovers, Blanco had been writing a book about a 1970s case dealing with the murder of several young schoolgirls in Paracuán by a man known as El Chaneque. Cabrera realizes that whoever killed Blanco wanted to keep the truth about El Chaneque from being revealed, and he becomes determined to discover that truth. The Black Minutes chronicles both Cabrera’s investigation into Blanco’s murder and goes back in time to follow detective Vicente Rangel’s investigation of the original El Chaneque case. Both narratives expose worlds of corruption, from cops who are content to close the door on a case without true justice to powerful politicians who can pay their way out of their families’ crimes. Full of dark twists and turns, and populated by a cast of captivating—and mostly corrupt—characters, The Black Minutes is an electrifying novel from a brilliant new voice. “Mr. Solares is a graceful, even poetic, writer, especially in his hard-boiled dialogue and his descriptions of the wildly varied landscapes and ethnic types of northern Mexico.” —Larry Rohter, The New York Times
Drugs and the Future presents 13 reviews collected to present the new advances in all areas of addiction research, including knowledge gained from mapping the human genome, the improved understanding of brain pathways and functions that are stimulated by addictive drugs, experimental and clinical psychology approaches to addiction and treatment, as well as both ethical considerations and social policy. The book also includes chapters on the history of addictive substances and some personal narratives of addiction. Introduced by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and Nora Volkow, director of the National Institute on Drug Abuse in the USA, the book uniquely covers the full range of disciplines which can provide insight into the future of addiction, from genetics to the humanities. Written for a scientific audience, it is also applicable to non-specialists as well. - Provides an unique overview of what we know about addiction, and how scientific knowledge can and should be applied in the societal, ethical, and political context - Applies the state-of-the-art research in fields such as Genomics, Neuroscience, Pharmacology, Social Policy and Ethics to addiction research - Includes a preface by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and in introduction by Nora Volkow, director of the National Institute on Drug Abuse in the USA
Cognitive impairment and depression in older people have challenged clinicians and families for decades. These conditions affect well over half of people after age 65 with an incidence that increases with advancing age. Many factors account for this including the aging brain, loss of purpose, social isolation, personal losses, medical morbidity, and others. The mortality, disability, and burdens associated with these conditions, affecting patients, family members, and society at large are legion. Advances in epidemiology, brain science, therapeutics, and in service delivery continue to improve our understanding of these conditions, their causes, and the best ways to treat them. Despite this cognitive impairment and depression in later life remain underdiagnosed and undertreated in the United States. This book provides a single source for clinicians who treat older people to become more effective in the evaluation, diagnosis, and treatment of these challenging late life conditions. It offers a pragmatic, easy-to-use, resource that guides clinicians in how to best evaluate and treat older people with depression and cognitive impairment.
This up-to-the-minute reference explores current trends, disease etiology and associations, novel assessment tools, and modern laboratory tests to promote coordinated treatment of comorbid substance abuse, psychiatric disease, and general medical conditions-recognizing the causal relationship between substance abuse and medical and psychiatric diso
This book covers the basic theory, practical details and advanced research of the implementation of evolutionary methods on physical substrates. Most of the examples are from electronic engineering applications, including transistor-level design and system-level implementation. The authors present an overview of the successes achieved, and the book will act as a point of reference for both academic and industrial researchers.
Highly Commended, Dermatology, BMA Awards 2009 Completely updated throughout—and still the only reference of its kind—the new edition of this well-respected resource offers you a practical guide for the evaluation, diagnosis, and management of a full range of common and uncommon obstetric and gynecologic skin disorders. Expanded coverage—including chapters on vulval vaginal disease help you meet more clinical challenges, while more than 460 illustrations emphasize pathologic and clinical appearances of dermatologic problems, providing essential visual guidance for the most informed diagnoses. Enhanced basic dermatologic information, such as general introductions to treatment, treatment options, and rashes, makes this an excellent guide for dermatologist and non-dermatologists, as well as obstetricians and gynecologists. Features the contributions of a team of international experts who provide a global perspective on today’s best practices. Provides exceptional visual guidance of both obstetric and gynecologic dermatoses, making this a convenient one-stop consultation reference. Includes more than 460 illustrations that clarify the key features of diseases and provide a greater “true-life practice perspective for making accurate diagnoses. Covers a full spectrum of conditions, including vulvar dermatoses, dermatoses of pregnancy, effect of pregnancy on other skin disorders, and more, to help you meet a full range of clinical challenges for diverse patient populations. Provides new information and illustrations in an expanded vulval section that equip you with a wider range of gynecologic dermatoses and treatment options for your most challenging clinical cases. Features the contributions of two new internationally recognized editors—known for their work in genital dermatology—who broaden the global appeal and relevance of the coverage.
Breads, salads, pasta, fondue, quesadillas, pizza, and quiche are our favorite comfort foods. And all have something in common—they're better with cheese! Multimillion-dollar marketing campaigns and international awards (not to mention those infamous Cheeseheads) have made Wisconsin cheese famous. That heritage is celebrated in this book that includes more than 100 recipes, cheesemaking (and eating) history and trivia, suggested wine pairings, a source list of fine cheese retailers, and much more.
Increasing performance demands in integrated circuits, together with limited energy budgets, force IC designers to find new ways of saving power. One innovative way is the presented adaptive voltage scaling scheme, which tunes the supply voltage according to the present process, voltage and temperature variations as well as aging. The voltage is adapted “on the fly” by means of in-situ delay monitors to exploit unused timing margin, produced by state-of-the-art worst-case designs. This book discusses the design of the enhanced in-situ delay monitors and the implementation of the complete control-loop comprising the monitors, a control-logic and an on-chip voltage regulator. An analytical Markov-based model of the control-loop is derived to analyze its robustness and stability. Variation-Aware Adaptive Voltage Scaling for Digital CMOS Circuits provides an in-depth assessment of the proposed voltage scaling scheme when applied to an arithmetic and an image processing circuit. This book is written for engineers interested in adaptive techniques for low-power CMOS circuits.
Nanosystems use new, nanoscopic electrical and/or mechanical devices which, as constituents of electronic and electromechanical systems, find application primarily in computing, embedded control and biomedical data acquisition. In particular, this book will deal with the characterization and patterning of these materials from an engineering perspective, with the objective of creating operational prototypes and products. The book will integrate various nano technologies on materials, devices and systems and identify key areas and results. The book will describe different design aspects for integrated systems on silicon, as well as on heterogeneous platforms including, but not limited to, electrical, optical, micromechanical and biological components in various forms and mixtures. By associating research topics from differing horizons, the book will provide a unique opportunity to bridge the gap between electronics/electrical engineering and materials science. The book will include topics at the intersection of these disciplines, and will interface with computer science, biology and medicine.
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