Martin Hardmeier's Books

Brain Stimulation

Chapter 46. Superficial brain stimulation in multiple sclerosis

By: Regina Schlaeger,Martin Hardmeier,Peter Fuhr

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Brain Stimulation

Chapter 46. Superficial brain stimulation in multiple sclerosis

By: Regina Schlaeger,Martin Hardmeier,Peter Fuhr

Central motor conduction time (CMCT) is the most frequently studied measure derived from transcranial magnetic stimulation (TMS) in multiple sclerosis (MS); it is abnormal in 57–93% of patients. Addition of the triple stimulation technique and combining motor with other evoked potentials (EPs) increases sensitivity. Cross-sectional correlations of TMS measures with clinical assessments of motor dysfunction or global disability are high. Longitudinally, CMCT is sensitive to both worsening and improvement of motor function, showing its potential to detect therapeutic responses. Moreover, combined multimodal EPs are valid quantitative predictors of the clinical course over periods ranging from 2 to 14 years. Measures of transcallosal connectivity (ipsilateral silent period and interhemispheric inhibition) are altered even in early MS, and yield complementary information on subclinical changes. Pathological brain plasticity in MS has been demonstrated by paired associative stimulation studies revealing a compensatory role of the ipsilateral motor and premotor areas. Central motor fatigue is associated with reduced motor EP amplitudes and increased cortical silent periods in normal controls, whereas patients with MS suffering from subjective fatigue show various abnormalities in cortical modulation of the motor system.

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Elsevier Inc. Chapters

Published Date

ISBN 10

0128080523

ISBN 13

9780128080528

Genomics and Society

Legal, Ethical and Social Dimensions

By: Martin W. Bauer

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Genomics and Society

Legal, Ethical and Social Dimensions

By: Martin W. Bauer

The impact of genomics on society has been the focus of debate and conflict across the world. Contrasting views of risks and benefits, trust in science and regulation, the understanding of science, media coverage and mobilization of the public by civil society groups all have been cited as drivers of public opinion. The long running controversy is a signal that the public's view cannot be ignored in the development and implementation of new technologies arising out of genomics such as agricultural biotechnologies, genetic testing and the uses of genetic information, the cloning of human cells and tissues and transgenic animals. Written by a progressive international group of social scientists from Europe, North America and Japan, this volume presents a series of comparative perspectives on the social, ethical and legal implications of genomics. The result is a book which encapsulates the lessons to be learned from the controversies of the 1990s and raises the level of debate on the societal implications of new developments in genomics.

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Page Count

278

Publisher

Routledge

Published Date

ISBN 10

1136548041

ISBN 13

9781136548048

The Song of the Sea

Ex 15:1 - 21

By: Martin L. Brenner

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The Song of the Sea

Ex 15:1 - 21

By: Martin L. Brenner

The series Beihefte zur Zeitschrift für die alttestamentliche Wissenschaft (BZAW) covers all areas of research into the Old Testament, focusing on the Hebrew Bible, its early and later forms in Ancient Judaism, as well as its branching into many neighboring cultures of the Ancient Near East and the Greco-Roman world.

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205

Publisher

Walter de Gruyter

Published Date

ISBN 10

3110867222

ISBN 13

9783110867220

Where Have All the Voters Gone?

By: Martin P. Wattenberg

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Where Have All the Voters Gone?

By: Martin P. Wattenberg

As the confusion over the ballots in Florida in 2000 demonstrated, American elections are complex and anything but user-friendly. This phenomenon is by no means new, but with the weakening of political parties in recent decades and the rise of candidate-centered politics, the high level of complexity has become ever more difficult for many citizens to navigate. Thus the combination of complex elections and the steady decline of the party system has led to a decline in voter turnout. In this timely book, Martin Wattenberg confronts the question of what low participation rates mean for democracy. At the individual level, turnout decline has been highest among the types of people who most need to have electoral decisions simplified for them through a strong party system--those with the least education, political knowledge, and life experience. As Wattenberg shows, rather than lamenting how many Americans fail to exercise their democratic rights, we should be impressed with how many arrive at the polls in spite of a political system that asks more of a typical person than is reasonable. Meanwhile, we must find ways to make the American electoral process more user-friendly.

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213

Publisher

Harvard University Press

Published Date

ISBN 10

0674044959

ISBN 13

9780674044951

Knowledge Lost

A New View of Early Modern Intellectual History

By: Martin Mulsow

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Knowledge Lost

A New View of Early Modern Intellectual History

By: Martin Mulsow

A compelling alternative account of the history of knowledge from the Renaissance to the Enlightenment Until now the history of knowledge has largely been about formal and documented accumulation, concentrating on systems, collections, academies, and institutions. The central narrative has been one of advancement, refinement, and expansion. Martin Mulsow tells a different story. Knowledge can be lost: manuscripts are burned, oral learning dies with its bearers, new ideas are suppressed by censors. Knowledge Lost is a history of efforts, from the Renaissance to the Enlightenment, to counter such loss. It describes how critics of ruling political and religious regimes developed tactics to preserve their views; how they buried their ideas in footnotes and allusions; how they circulated their tracts and treatises in handwritten copies; and how they commissioned younger scholars to spread their writings after death. Filled with exciting stories, Knowledge Lost follows the trail of precarious knowledge through a series of richly detailed episodes. It deals not with the major themes of metaphysics and epistemology, but rather with interpretations of the Bible, Orientalism, and such marginal zones as magic. And it focuses not on the usual major thinkers, but rather on forgotten or half-forgotten members of the “knowledge underclass,” such as Pietro della Vecchia, a libertine painter and intellectual; Charles-César Baudelot, an antiquarian and numismatist; and Johann Christoph Wolf, a pastor, Hebrew scholar, and witness to the persecution of heretics. Offering a fascinating new approach to the intellectual history of early modern Europe, Knowledge Lost is also an ambitious attempt to rethink the very concept of knowledge.

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456

Publisher

Princeton University Press

Published Date

ISBN 10

0691208654

ISBN 13

9780691208657

Discourse and Discrimination

Rhetorics of Racism and Antisemitism

By: Martin Reisigl,Ruth Wodak

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Discourse and Discrimination

Rhetorics of Racism and Antisemitism

By: Martin Reisigl,Ruth Wodak

Discourse and Discrimination is a study of how racism, antisemitism and ethnicism are reflected in discourse. Drawing on a wide range of sources- Reisisl and Wodak question why even today, racism and antisemitism are still virulent.

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Page Count

313

Publisher

Routledge

Published Date

ISBN 10

1134579578

ISBN 13

9781134579570

Book's by Martin Hardmeier

Brain Stimulation

Brain Stimulation

Genomics and Society

Genomics and Society

The Song of the Sea

The Song of the Sea

Where Have All the Voters Gone?

Where Have All the Voters Gone?

Knowledge Lost

Knowledge Lost

Discourse and Discrimination

Discourse and Discrimination

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