Einstein proposed his theory of special relativity in 1905. For a long time it was believed that this theory has no significant impact on chemistry. This view changed in the 1970s when it was realized that (nonrelativistic) Schrodinger quantum mechanics yields results on molecular properties that depart significantly from experimental results. Especially when heavy elements are involved, these quantitative deviations can be so large that qualitative chemical reasoning and understanding is affected. For this to grasp the appropriate many-electron theory has rapidly evolved. Nowadays relativistic approaches are routinely implemented and applied in standard quantum chemical software packages. As it is essential for chemists and physicists to understand relativistic effects in molecules, the first edition of "Relativistic Quantum Chemistry - The fundamental Theory of Molecular Science" had set out to provide a concise, comprehensive, and complete presentation of this theory. This second edition expands on some of the latest developments in this fascinating field. The text retains its clear and consistent style, allowing for a readily accessible overview of the complex topic. It is also self-contained, building on the fundamental equations and providing the mathematical background necessary. While some parts of the text have been restructured for the sake of clarity a significant amount of new content has also been added. This includes, for example, an in-depth discussion of the Brown-Ravenhall disease, of spin in current-density functional theory, and of exact two-component methods and its local variants. A strength of the first edition of this textbook was its list of almost 1000 references to the original research literature, which has made it a valuable reference also for experts in the field. In the second edition, more than 100 additional key references have been added - most of them considering the recent developments in the field. Thus, the book is a must-have for everyone entering the field, as well as for experienced researchers searching for a consistent review.
A practical handbook written for the practising physician, 'Stroke Medicine' provides an up-to-date, and easily accessible source of information on all aspects of stroke care from acute care, through to rehabilitation and secondary prevention.
This innovative book brings together two disciplines — science and art — and enables readers to produce their own computer-generated displays. 44 colour plates and 200 black and white pictures showcase the diagrams that can easily be reproduced using the accompanying CD-ROM. It is possible to create diagrams that indicate predictability or unpredictability of physical, chemical, ecological, mathematical or economic systems. Grey levels and colours indicate the stability of a predictable system, or the extent of unpredictability. In addition, diagrams can be drawn purely for their aesthetic value. Directed both at scientists and laymen, technicians and artists, this combination of book and CD-ROM is the first of its kind./aDownload Images as Wallpapers:
The relevance of software business models has tremendously increased in recent years. Markus Schief explores opportunities to improve the management of these models. Based on a conceptual framework of software business model characteristics, he conducts large empirical studies to examine the current state of business models in the software industry. These data then serve as a foundation for statistical analyses of business models’ impact on firm and M&A performance. Finally, the author develops a software business model management tool.
Questions relating to (im)migration are among the most heated topics on both sides of the Atlantic. Western societies have changed dramatically because of large-scale immigration in the last decades. Christians are also engaged in the discussion, attempting to find direction from the biblical texts. Overwhelmingly, persons in leading positions (both in the secular world and in churches and faith-based organizations) support the concept of “welcoming the stranger.” The Bible is seen by them as urging us to open the borders as wide as we can. In the broader population, however, reservations remain. This book, written by a Bible professor who has witnessed mass-migration first-hand, both in Europe and in the U.S., and who has been a migrant himself for over twenty years, attempts to step back and look at the whole of the complex biblical witness, instead of cherry-picking passages that further a specific agenda. It also looks at the salient data on the ground, in the fields of psychology, demography, economy, and security—data that can no longer be ignored when trying to apply the Bible in a responsible way. The book demonstrates the shortcomings of the vast majority of biblical and theological publications on the issue of (im)migration and presents a comprehensive argument for the use of wisdom and caution, and against short-sighted and emotionally driven policies supporting open borders.
A thorough introduction to solar physics based on recent spacecraft observations. The author introduces the solar corona and sets it in the context of basic plasma physics before moving on to discuss plasma instabilities and plasma heating processes. The latest results on coronal heating and radiation are presented. Spectacular phenomena such as solar flares and coronal mass ejections are described in detail, together with their potential effects on the Earth.
Biophysical Chemistry explores the concepts of physical chemistry and molecular structure that underlie biochemical processes. Ideally suited for undergradate students and scientists with backgrounds in physics, chemistry or biology, it is also equally accessible to students and scientists in related fields as the book concisely describes the fundamental aspects of biophysical chemistry, and puts them into a biochemical context. The book is organized in four parts, covering thermodynamics, kinetics, molecular structure and stability, and biophysical methods. Cross-references within and between these parts emphasize common themes and highlight recurrent principles. End of chapter problems illustrate the main points explored and their relevance for biochemistry, enabling students to apply their knowledge and to transfer it to laboratory projects. Features: Connects principles of physical chemistry to biochemistry Emphasizes the role of organic reactions as tools for modification and manipulation of biomolecules Includes a comprehensive section on the theory of modern biophysical methods and their applications
Providing much-needed information on fluorescence spectroscopy and microscopy, this ready reference covers detection techniques, data registration, and the use of spectroscopic tools, as well as new techniques for improving the resolution of optical microscopy below the resolution gap. Starting with the basic principles, the book goes on to treat fluorophores and labeling, single-molecule fluorescence spectroscopy and enzymatics, as well as excited state energy transfer, and super-resolution fluorescence imaging. Examples show how each technique can help in obtaining detailed and refined information from individual molecular systems.
This book brings home the message that meticulous integration management is the key to success in M&A transactions. Half of all M&A transactions are unsuccessful because many companies embarking on a merger neglect this key success factor. Based on 30 years of experience of corporate mergers and acquisitions as well as the subsequent implementation of growth strategies, the authors have developed a practical manual that helps managers optimize and streamline their growth strategy using persistent integration and transformation management. The book provides first-hand accounts of M&A transactions that the authors led or were involved in, assessing each case from an insider perspective and outlining the key success factors and pitfalls. It concludes with practical checklists including the most relevant topics for each individual step toward successful integration.
Echoes of Aquinas in Cusanus’s Vision of Man demonstrates the influence that the philosophical and theological anthropology of Saint Thomas Aquinas had on Nicholas of Cusa’s (Cusanus) view of human nature. Markus Führer demonstrates that Cusanus's view of the place of man in the universe is remarkably similar to the view of Aquinas. Führer thereby challenges the prevailing opinion that Cusanus was a Renaissance philosopher dedicated to the philosophy of man and that he was one of the founders of Renaissance humanism. A close examination of the texts of both Aquinas and Cusanus, when compared to some of the leading Renaissance writers, indicates that it is not entirely true that Cusanus was Renaissance in his analysis of the human condition. Because Cusanus’s copies of some of the works of Aquinas are still intact and his marginal comments in these manuscripts indicate not only that he read Aquinas carefully, but also actually reacted to texts in Aquinas, it is possible to conduct a study of Cusanus’s use of Aquinas based directly on the text of Aquinas. Führer also explores similarities by studying the formulae that both writers used in expressing their respective positions. This book, with its unique examination of the impact of Aquinas’s thought upon Cusanus, will appeal to students and scholars of late medieval theology and philosophy.
Research in context-aware computing has produced a number of middleware systems for context management. However, development of ubiquitous context-aware applications is still a challenge because most current middleware systems are still focused on isolated and static context-aware environments. Context-aware environments are inherently dynamic as a result of occasional additions or upgrade of sensors, applications or context inference mechanisms. Context Management for Distributed and Dynamic Context-Aware Computing proposes a novel architecture for context management based on the concept of context domains, allowing applications to keep context interests across distributed context management systems. The authors describe a distributed middleware that implements the aforementioned concepts, without compromising scalability and efficiency of context access.
Over the last decade we entered a new exploration phase of solar flare physics, equipped with powerful spacecraft such as Yohkoh, SoHO, and TRACE that pro vide us detail-rich and high-resolution images of solar flares in soft X-rays, hard X -rays, and extreme-ultraviolet wavelengths. Moreover, the large-area and high sensitivity detectors on the Compton GRO spacecraft recorded an unprecedented number of high-energy photons from solar flares that surpasses all detected high energy sources taken together from the rest of the universe, for which CGRO was mainly designed to explore. However, morphological descriptions of these beau tiful pictures and statistical catalogs of these huge archives of solar data would not convey us much understanding of the underlying physics, if we would not set out to quantify physical parameters from these data and would not subject these measurements to theoretical models. Historically, there has always been an unsatisfactory gap between traditional astronomy that dutifully describes the mor phology of observations, and the newer approach of astrophysics, which starts with physical concepts from first principles and analyzes astronomical data with the goal to confirm or disprove theoretical models. In this review we attempt to bridge this yawning gap and aim to present the recent developments in solar flare high-energy physics from a physical point of view, structuring the observations and analysis results according to physical processes, such as particle acceleration, propagation, energy loss, kinematics, and radiation signatures.
World Bank Discussion Paper No. 331. With the assistance of Emilio Mondo, Taimi Sitari, and Tadesse A. Woldu. Provides a detailed analysis of the intricate nature of the political, economic, and sociocultural issues that arise during the transition from war to peace in Ethiopia, Namibia, and Uganda. These countries offer a unique range of conditions and program models, as well as a variety of successes and failures from which to learn. A recently released overview, The Transition from War to Peace in Sub-Saharan Africa (Stock no. 13581; ISBN 0-8213-3581-2), is based on these country studies and a synthesis of reports of demobilization and reintegration programs in several other countries.
Biomateriomics is the holistic study of biological material systems. While such systems are undoubtedly complex, we frequently encounter similar components -- universal building blocks and hierarchical structure motifs -- which result in a diverse set of functionalities. Similar to the way music or language arises from a limited set of music notes and words, we exploit the relationships between form and function in a meaningful way by recognizing the similarities between Beethoven and bone, or Shakespeare and silk. Through the investigation of material properties, examining fundamental links between processes, structures, and properties at multiple scales and their interactions, materiomics explains system functionality from the level of building blocks. Biomateriomics specifically focuses the analysis of the role of materials in the context of biological processes, the transfer of biological material principles towards biomimetic and bioinspired applications, and the study of interfaces between living and non-living systems. The challenges of biological materials are vast, but the convergence of biology, mathematics and engineering as well as computational and experimental techniques have resulted in the toolset necessary to describe complex material systems, from nano to macro. Applying biomateriomics can unlock Nature’s secret to high performance materials such as spider silk, bone, and nacre, and elucidate the progression and diagnosis or the treatment of diseases. Similarly, it contributes to develop a de novo understanding of biological material processes and to the potential of exploiting novel concepts in innovation, material synthesis and design.
This practical guide for advanced students and decision-makers in the pharma and biotech industry presents key success factors in R&D along with value creators in pharmaceutical innovation. A team of editors and authors with extensive experience in academia and industry and at some of the most prestigious business schools in Europe discusses in detail the innovation process in pharma as well as common and new research and innovation strategies. In doing so, they cover collaboration and partnerships, open innovation, biopharmaceuticals, translational medicine, good manufacturing practice, regulatory affairs, and portfolio management. Each chapter covers controversial aspects of recent developments in the pharmaceutical industry, with the aim of stimulating productive debates on the most effective and efficient innovation processes. A must-have for young professionals and MBA students preparing to enter R&D in pharma or biotech as well as for students on a combined BA/biomedical and natural sciences program.
Presents modeling approaches that can be performed in SysML and other modeling languages This book combines the emerging discipline of systems architecting with model-based approaches using SysML. The early chapters of the book provide the fundamentals of systems architecting; discussing what systems architecting entails and how it benefits systems engineering. Model-based systems engineering is then defined, and its capabilities to develop complex systems on time and in a feasible quality are discussed. The remainder of the book covers important topics such as: architecture descriptions; architecture patterns; perspectives, viewpoints, views and their relation to system architecture; the roles of a system architect, their team, and stakeholders; systems architecting processes; agile approaches to systems architecting; variant modeling techniques; architecture frameworks; and architecture assessment. The book's organization allows experts to read the chapters out of sequence. Novices can read the chapters sequentially to gain a systematic introduction to system architecting. Model-Based System Architecture: Provides comprehensive coverage of the Functional Architecture for Systems (FAS) method created by the authors and based on common MBSE practices Covers architecture frameworks, including the System of Systems, Zachman Frameworks, TOGAF®, and more Includes a consistent example system, the “Virtual Museum Tour” system, that allows the authors to demonstrate the systems architecting concepts covered in the book Model-Based System Architecture is a comprehensive reference for system architects and systems engineers in technology companies. This book will also serve as a reference to students and researchers interested in functional architectures. Tim Weilkiens is the CEO at the German consultancy oose Innovative Informatik and co-author of the SysML specification. He has introduced model-based systems engineering to a variety of industry sectors. He is author of several books about modeling and the MBSE methodology SYSMOD. Jesko G. Lamm is a Senior Systems Engineer at Bernafon, a Swiss manufacturer for hearing instruments. With Tim Weilkiens, Jesko G. Lamm founded the Functional Architectures working group of the German chapter of INCOSE. Stephan Roth is a coach, consultant, and trainer for systems and software engineering at the German consultancy oose Innovative Informatik. He is a state-certified technical assistant for computer science from Physikalisch-Technische Lehranstalt (PTL) Wedel and a certified systems engineer (GfSE)®- Level C. Markus Walker works at Schindler Elevator in the research and development division as elevator system architect. He is an INCOSE Certified Systems Engineering Professional (CSEP) and is engaged in the committee of the Swiss chapter of INCOSE.
Semiconductor quantum optics is on the verge of moving from the lab to real world applications. When stepping from basic research to new technologies, device engineers will need new simulation tools for the design and optimization of quantum light sources, which combine classical device physics with cavity quantum electrodynamics. This thesis aims to provide a holistic description of single-photon emitting diodes by bridging the gap between microscopic and macroscopic modeling approaches. The central result is a novel hybrid quantum-classical model system that self-consistently couples semi-classical carrier transport theory with open quantum many-body systems. This allows for a comprehensive description of quantum light emitting diodes on multiple scales: It enables the calculation of the quantum optical figures of merit together with the simulation of the spatially resolved current flow in complex, multi-dimensional semiconductor device geometries out of one box. The hybrid system is shown to be consistent with fundamental laws of (non-)equilibrium thermodynamics and is demonstrated by numerical simulations of realistic devices.
As a continuation of classical condensed matter physics texts, this graduate textbook introduces advanced topics of correlated electron systems, mesoscopic transport,quantum computing, optical excitations and topological insulators. The book is focusing on an intuitive understanding of the basic concepts of these rather complex subjects.
This is a follow-on book to the introductory textbook "Physics of the Solar Corona" previously published in 2004 by the same author, which provided a systematic introduction and covered mostly scientific results from the pre-2000 era. Using a similar structure as the previous book the second volume provides a seamless continuation of numerous novel research results in solar physics that emerged in the new millennium (after 2000) from the new solar missions of RHESSI, STEREO, Hinode, CORONAS, and the Solar Dynamics Observatory (SDO) during the era of 2000-2018. The new solar space missions are characterized by unprecedented high-resolution imaging, time resolution, spectral capabilities, stereoscopy and tomography, which reveal the intricate dynamics of magneto-hydrodynamic processes in the solar corona down to scales of 100 km. The enormous amount of data streaming down from SDO in Terabytes per day requires advanced automated data processing methods. The book focuses exclusively on new research results after 2000, which are reviewed in a comprehensive manner, documented by over 3600 literature references, covering theory, observations, and numerical modeling of basic physical processes that are observed in high-temperature plasmas of the Sun and other astrophysical objects, such as plasma instabilities, coronal heating, magnetic reconnection processes, coronal mass ejections, plasma waves and oscillations, or particle acceleration.
Oil and Gas explores the business and politics of this complex industry from a regional perspective. This book combines theory, practice and a range of international case studies to provide a comprehensive overview of energy management.
Political interest is the strongest predictor of 'good citizenship', yet hardly anything is known about it. For the first time in over three decades, here is a study explaining what political interest is, where it comes from, and why it matters. Providing the most thorough description available of political interest in four Western democracies this study analyzes large household panel data sets rarely used in political science to explain how interest develops in people's lives. In an accessible manner, the book's analytical approach pushes applied social scientists to consider how panel data can be used to better understand political behavior. It does so in a way that doesn't gloss over complexities, and explains them in straightforward language. Advanced statistical methods are presented informally, accompanied by graphical illustrations that require no prior knowledge to understand the methods used.
The on-time delivery of goods is regarded as a primary factor of the urban economy and is being monitored by businesses and government alike. However, much analysis of freight transportation and the flow of goods into, out of and within urban areas focuses on functional, business-related approaches. This book examines the interrelationship between logistics development on one hand and urban development and geographical issues, such as land use and location, on the other. Avoiding certain one-dimensional views on 'logistics impacts on the city', it discloses the complex interaction of the logistics system with the entire urban environment. It also bridges the gap between recent geographical research into new production systems and (post)modern consumption patterns. Illustrated with case studies from the United States, Germany, France, The Netherlands and the United Kingdom, it examines issues such as: the historical nexus between urban areas and logistics; current urban developments with regards to goods distribution; city-region related characteristics of freight flows; locational dynamics; and specific freight related urban problems and conflicts.
This open access Springer Brief provides a systematic analysis of current trends and requirements in the areas of knowledge and competence in the context of the project “(A) Higher Education Digital (AHEAD)—International Horizon Scanning / Trend Analysis on Digital Higher Education.” It examines the latest developments in learning theory, didactics, and digital-education technology in connection with an increasingly digitized higher education landscape. In turn, this analysis forms the basis for envisioning higher education in 2030. Here, four learning pathways are developed to provide a glimpse of higher education in 2030: Tamagotchi, a closed ecosystem that is built around individual students who enter the university soon after secondary education; Jenga, in which universities offer a solid foundation of knowledge to build on in later phases; Lego, where the course of study is not a monolithic unit, but consists of individually combined modules of different sizes; and Transformer, where students have already acquired their own professional identities and life experiences, which they integrate into their studies. In addition, innovative practice cases are presented to illustrate each learning path.
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