This book contributes to the scientific field of optimal control theory applied to dynamic models of the firm. It discusses optimal investment, financing and production policies of the firm, that have to deal with a variety of aspects, such as financial constraints, start-up costs, business cycles, increasing returns to scale, production life cycles and experience curves. In contrast to many other publications on this subject, here, in combination with an analytical approach, the dynamic optimization problems are solved numerically with the aid of a powerful computer and specific programs for optimizing non-linear functions of a finite number of variables and non-linear constraints.
Examines effects of the environmental distribution of antimicrobial resistance genes on human health and the ecosystem Resistance genes are everywhere in nature—in pathogens, commensals, and environmental microorganisms. This contributed work shows how the environment plays a pivotal role in the development of antimicrobial resistance traits in bacteria and the distribution of resistant microbial species, resistant genetic material, and antibiotic compounds. Readers will discover the impact of the distribution in the environment of antimicrobial resistance genes and antibiotics on both the ecosystem and human and animal health. Antimicrobial Resistance in the Environment is divided into four parts: Part I, Sources, including ecological and clinical consequences of antibiotic resistance by environmental microbes Part II, Fate, including strategies to assess and minimize the biological risk of antibiotic resistance in the environment Part III, Antimicrobial Substances and Resistance, including antibiotics in the aquatic environment Part IV, Effects and Risks, including the effect of antimicrobials used for non-human purposes on human health Recognizing the intricate links among overlapping complex systems, this book examines antimicrobial resistance using a comprehensive ecosystem approach. Moreover, the book's multidisciplinary framework applies principles of microbiology, environmental toxicology, and chemistry to assess the human and ecological risks associated with exposure to antibiotics or antibiotic resistance genes that are environmental contaminants. Each chapter has been written by one or more leading researchers in such fields as microbiology, environmental science, ecology, and toxicology. Comprehensive reference lists at the end of all chapters serve as a gateway to the primary research in the field. Presenting and analyzing the latest findings in a field of growing importance to human and environmental health, this text offers readers new insights into the role of the environment in antimicrobial resistance development, the dissemination of antimicrobial resistant genetic elements, and the transport of antibiotic resistance genes and antibiotics.
Providing critical insights that will interest readers ranging from economists to environmentalists, policymakers, and politicians, this book analyzes the economics and technology trends involved in the dilemma of decarbonization and addresses why aggressive policy is required in a capitalist political economy to create a sea change away from fossil fuels. The environmental damage across the globe is a result of the success of capitalist industrialism—250 years of carbon pollution resulting from consumption of fossil fuels to drive the economy and the worldwide aspiration to ever-increasing levels of economic development. But capitalism has also produced the tools to solve the problems it has created in the form of a technological revolution in low-carbon renewables, distributed resources, and intelligent systems to integrate supply and demand. This book comprehensively examines the political economy of electricity and analyzes the challenge of transforming today's electricity sector to meet the dual goals of decarbonization and development expressed in the Paris Agreement. Author Mark Cooper defines the dilemma of development and decarbonization as the great challenge facing the electricity industry and documents how the economic resources costs of a 100 percent-renewable portfolio has declined to the point that decarbonization can pay for itself, making the low-carbon renewable technologies that enable desired environmental and public-health benefits an easy sell. He identifies the substantial benefit of increasing use of information, communications, and advanced control technologies; shows how targeted innovation could speed the transition by a decade or two and lower the overall cost of the transition by as much as half; and explains why the flexible, multi-stakeholder approach of the Paris Agreement is the correct approach.
Edited and authored by some of the most respected figures in the field, this newly revised book is your comprehensive guide to all areas of urogynecology, including urinary and fecal incontinence, urodynamic testing, management of genuine stress incontinence, pelvic organ prolapse, overactive bladder, and much more. Uniquely organized to reflect a physician's decision-making process, this practical, clinically oriented text moves from basic concepts through to clinical and urodynamic evaluation, management, and treatment. Inside, you'll find evidence-based assessments of appropriate therapies, along with algorithmic approaches to common complaints, and clear surgical illustrations. Exclusive to the third edition is a section addressing painful and irritative voiding disorders, including overactive bladder, as well as 20 new case presentations that offer opinions from the leading experts in urogynecology and urology. Features step-by-step instructions for urodynamic testing. Addresses all urogynecologic disorders, including genuine stress incontinence · pelvic organ prolapse · defecation disorders · painful and irritative voiding disorders · and specific conditions such as urinary tract infection. Presents vital information on urethral injections, covering the newest treatment options available. Examines the use of autologous materials and mesh in reconstructive pelvic surgery. Uses over 300 crisp illustrations to illuminate every detail. Contains a new section on painful and irritative voiding disorders, including a discussion of overactive bladder and the latest treatment options available. Discusses urodynamics and the most up-to-date testing available for urethral sphincteric function. Features 20 all new case presentations with expert commentary.
This fourth edition offers a practical guide to endovascular treatment of cerebrovascular disease and provides a comprehensive reference for the related neurovascular anatomy and the various disorders that affect the vascular system. Chapters cover fundamental principles underlying cerebral and spinal angiography; interventional techniques, devices, and practice guidelines; and commonly encountered cerebrovascular disorders for which interventional and endovascular methods are appropriate Building on the previous edition, the text is presented similarly in style and scope to emphasize accessibility and ease of reading. All chapters are fully updated to include more recent data, and obsolete products and techniques are replaced with the most current technology. Some key updates include: A greater emphasis on the use of radial artery access for the discussed endovascular techniques. The associations of COVID-19 with ischemic stroke and the implications of providing care for cerebrovascular patients during a pandemic. An extensive update to the acute ischemic stroke chapter with new references and format to more closely follow the format of other chapters in that section. Expansion of the pediatric sections of disease chapters, including discussions of genetic associations with disease. This is an ideal guide for clinicians and trainees in neurology, neurosurgery and neuroradiology, as well as practicing clinicians in related fields caring for patients with cerebrovascular disease.
Edited and authored by some of the most respected figures in the field, Urogynecology and Reconstructive Pelvic Surgery presents definitive, state-of-the-art guidance on every aspect of Female Pelvic Medicine and Reconstructive Surgery (FPMRS), equipping you to make the best clinical decisions and optimize outcomes. Its easily accessible format is uniquely organized to reflect a physician's decision-making process -- from basic concepts through to clinical and urodynamic evaluation, management, and treatment. This practical, clinically oriented text is an ideal resource for OB/GYNs and Urologists as well as subspecialists in FPMRS, providing the latest information on procedures and available research regarding the evaluation and treatment of the growing number of patients presenting with these types of conditions. Glean all essential, up-to-date, need-to-know information with a new section on surgical complications and their management; important new discussions on the psychosocial issues associated with treating patients with female pelvic floor disorders; and a new focus on female sexual function and dysfunction. Prevent and plan for complications prior to a procedure thanks to a step-by-step approach to each procedure, complete with personal techniques and tips from leading experts. Put concepts into practice. Case presentations from leading experts in FPMRS allow the reader to apply the information presented to everyday clinical situations. Effectively detect, prevent and treat common female pelvic floor disorders including stress incontinence, overactive bladder, pelvic organ prolapse, defecation disorders, painful bladder and irritative voiding disorders, and urinary tract infection. Get a true-to-life view of each procedure through full-color, crisp illustrations that illuminate every detail and nuance. Stay current the latest advancements and developments with sweeping updates and 9 NEW chapters: Congenital Anomalies of the Female Genital and Urinary Tracts l Physiology of the Pelvic Muscles, Vagina and Ano-Rectum l Female Sexual Function and Dysfunction l Multichannel-Urodynamics: Indications, Techniques and Interpretation with Case Studies l Video and Ambulatory Urodynamics: Indications, Techniques and Interpretation with Case Studies l Hysteropexy l Avoiding and Managing Lower Urinary Tract Injuries During Pelvic Surgery l Managing Mesh and other Vaginal Complications after Surgeries for Incontinence and Prolapse l and Surgical Management of Detrusor Compliance Abnormalities. Master urodynamic testing with step-by-step instructions on basic evaluation as well as the evaluation of complex cases with videourodynamics. Know what to do and expect with algorithmic approaches to common complaints, evidence-based assessments of appropriate therapies, and clear full-color surgical illustrations as well as evidence-based assessments of appropriate therapies.
This third Edition is a completely new version in a new century of the Encyclopedia of Polymer Science and Technology. The new edition will bring the state-of-the-art up to the 21st century, with coverage of nanotechnology, new imaging and analytical techniques, new methods of controlled polymer architecture, biomimetics, and more. New topics covered include nanotechnology, AFM, MALDI, biomimetics, and genetic methods, of increasing importance since 1990 and will also bring up-to-date coverage of traditional topics of continuing interest. This edition will publish in 3 Parts of 4 volumes each. Each Part will be an A-Z selection of the newest articles available in the online edition of this encyclopedia. A list of the titles to appear in Part I can be viewed by clicking "What's New" at www.mrw.interscience.wiley.com/epst. Titles for Parts II and III will appear there as well when available.
This book contributes to the scientific field of optimal control theory applied to dynamic models of the firm. It discusses optimal investment, financing and production policies of the firm, that have to deal with a variety of aspects, such as financial constraints, start-up costs, business cycles, increasing returns to scale, production life cycles and experience curves. In contrast to many other publications on this subject, here, in combination with an analytical approach, the dynamic optimization problems are solved numerically with the aid of a powerful computer and specific programs for optimizing non-linear functions of a finite number of variables and non-linear constraints.
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