Game fishes, particularly those of the salmon family, are critical indicators of the health of those ecosystems upon which we now know we are dependent. As the authors of this important environmental book argue, “Our game fishes [then] serve as more than merely an indicator of healthy waters. Instead, they can be regarded as iconic of the ecosystems in which they occur.” Moreover, “the quality requirements of different types of fish population have formed the backbone of a great deal of water management in the UK, Europe and the USA over several decades.” With sections on how and why Britain’s game fishes are under pressure from changes in land use, agriculture, housing needs, etc. – and their concomitant pollution effects – this book assesses how our knowledge of these game fishes reflect the changing values we place on our surrounding wildlife.
The foundation for targeted therapy of cancers driven by members of the ErbB oncoprotein family was established initially by the demonstration that ectodomain binding monoclonal antibodies (mAb) could disable the protein kinase encoded by the HER2/neu oncogene. Homomeric and heteromeric erbB kinases play critical roles in the development of cancer and in the spread of early lesions. In particular, antibodies targeting the p185erbB2/neu receptor provide major clinical benefits in the treatment of breast cancer and also stomach cancer. As suggested by our study with oncogenic neu transgenic mice, anti-p185erbB2/neu antibodies are also effective in preventing the tissue hyperplasia that precedes tumorigenesis, tumor growth and the dissemination of ErbB2/neu kinase-positive cells into other tissues. As a therapeutic principle, “reversion of phenotype” for established tumors and “prevention” of tumorigenesis and spread can explain the basis for the benefits invoked by therapeutic and adjuvant therapies for breast cancer patients after cancers are surgically removed. These emerging principles being enlightened by ongoing studies of monoclonal antibody therapy will continue to provide guidance for the development of new targeted therapies for resistant tumors that arise after treatment.
This accessible textbook draws upon progressions in academic, political and global arenas, to provide a comprehensive overview of practical issues in psychological work across a diverse range of community settings. Interest in community psychology, and its potential as a distinctive approach, is growing and evolving in parallel with societal and policy changes. Thoroughly revised and updated, this new edition covers crucial issues including decolonial approaches, migration, social justice, and the environmental crisis. It has a new chapter on archive research, working with data, policy analysis and development, to reflect the continuously developing global nature of community psychology. Key features include: Sections and chapters organised around thinking, acting and reflecting Case examples and reflections of community psychology in action Discussion points and ideas for exercises that can be undertaken by the reader, in order to extend critical understanding Aiming to provide readers with not only the theories, values and principles of community psychology, but also with the practical guidance that will underpin their community psychological work, this is the ideal resource for any student of community, social, and clinical psychology, social work, community practice, and people working in community-based professions and applied settings.
Evidence and knowledge are fundamental in professional practice. A key skill for social workers is understanding how to use the range of sources available. This book recognizes and builds on the complex nature of social work practice.
High purity, thin metal coatings have a variety of important commercial applications, for example, in the microelectronics industry, as catalysts, as protective and decorative coatings as well as in gas-diffusion barriers. This book offers detailed, up- to-date coverage of the chemistry behind the vapor deposition of different metals from organometallic precursors. In nine chapters, the CVD of metals including aluminum, tungsten, gold, silver, platinum, palladium, nickel, as well as copper from copper(I) and copper(II) compounds is covered. The synthesis and properties of the precursors, the growth process, morphology, quality and adhesion of the resulting films as well as laser- assisted, ion- assisted and plasma-assisted methods are discussed. Present applications and prospects for future developments are summarized. With ca. 1000 references and a glossary, this book is a unique source of in-depth information. It is indispensable for chemists, physicists, engineers and materials scientists working with metal- coating processes and technologies. From Reviews: 'I highly recommend this book to anyone interested in learning more about the chemistry of metal CVD.' J. Am Chem. Soc.
In its list of the "Top 10 Badass Marines," Leatherneck magazine declared that Major George W. Hamilton "never asked anyone to do anything he wasn't prepared to do himself...and do better." Indeed, the author of A History of the United States Marine Corps once called Hamilton "the most outstanding Marine Corps hero in World War I." A leader of the first major American assault on June 6, 1918, and the last ranking officer in the American Expeditionary Forces to learn that the war was over, Hamilton remained in the thick of the fighting from start to finish. Although he earned the Distinguished Service Cross, the Navy Cross, the Croix de Guerre, and two Medal of Honor recommendations for his service, Hamilton's fame stalled when he died prematurely in 1922. With this first complete biography, Hamilton takes his rightful place among the first rank of American military heroes.
For almost thirty years The Civil War Dictionary has been the most complete, authoritative, and handy reference book on what has been called the Second American Revolution, 1861-1865. Periodically updated throughout sixteen printings, this invaluable volume has more than 4,000 entries, alphabetically arranged and carefully cross-referenced. Among them: -- 2,000 biographical sketches of Civil War leaders. both military and civilian -- extensive descriptions of all 20 campaigns and entries on lesser battles, engagements and skirmishes -- 120 armies, departments, and districts, as well as such famous smaller units as the Iron Brigade, the 20th Maine, and the Pennsylvania Reserves -- plus naval engagements, weapons, issues and incidents, military terms and definitions, politics, literature, statistics, and 86 specially prepared maps and diagrams
Beginning with the homes of the first European settlers to the North American colonies, and concluding with the latest trends in construction and design of houses and apartments in the United States, Homes through American History is a four-volume set intended for a general audience. From tenements to McMansions, from wattle-and-daub construction in early New England to sustainable materials for green housing, these books provide a rich historical tour through housing in the United States. Divided into 10 historical periods, the series explores a variety of home types and issues within a social, historical, and political context. For use in history, social studies, and literature classes, Homes through American History identifies ; A brief historical overview of the era, in order provide context to the discussion of homes and dwellings. ; Styles of domestic architecture around the country. ; Building material and manufacturing. ; Home layout and design. ; Furniture and decoration. ; Landscaping and outbuildings.
Offering a state-of-the-art, authoritative summary of the most relevant scientific and clinical advances in the field, Principles and Practice of Movement Disorders provides the expert guidance you need to diagnose and manage the full range of these challenging conditions. Superb summary tables, a large video library, and a new, easy-to-navigate format help you find information quickly and apply it in your practice. Based on the authors' popular Aspen Course of Movement Disorders in conjunction with the International Parkinson and Movement Disorder Society, this 3rd Edition is an indispensable resource for movement disorder specialists, general neurologists, and neurology residents. - Explores all facets of movement disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. - Provides the essential information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. - Reflects recent advances in areas such as the genetics of Parkinsonian and other movement disorders, diagnostic brain imaging, new surgical approaches to patients with movement disorders, and new treatment guidelines for conditions such as restless legs syndrome. - Features a reader-friendly, full-color format, with plentiful diagrams, photographs, and tables. - Includes access to several hundred updated, professional-quality video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.