This English-language translation of Mark Hengerer's Kaiser Ferdinand III: 1608–1657 Eine Biographie is based on an analysis of the weekly reports sent by the papal nuncio’s office to the Vatican. These reports give detailed information about the daily whereabouts of the dynasty, courtiers, and foreign visitors, and they contain the gossip of the court in addition to weekly analysis of some political problems. This material enabled the author to report on daily life of the dynasty and to analyze the circumstances under which policy was made, which has led to a balance between the personality of Ferdinand III and the problems with which he dealt. In this biography, Hengerer provides answers to the question: Why did it take the emperor more than ten years to end a devastating war, the traumatizing effects of which on central Europe lasted into the twentieth century, particularly since there was no hope of victory against his foreign adversaries from the very moment he came into power?
This English-language translation of Mark Hengerer's Kaiser Ferdinand III: 1608–1657 Eine Biographie is based on an analysis of the weekly reports sent by the papal nuncio’s office to the Vatican. These reports give detailed information about the daily whereabouts of the dynasty, courtiers, and foreign visitors, and they contain the gossip of the court in addition to weekly analysis of some political problems. This material enabled the author to report on daily life of the dynasty and to analyze the circumstances under which policy was made, which has led to a balance between the personality of Ferdinand III and the problems with which he dealt. In this biography, Hengerer provides answers to the question: Why did it take the emperor more than ten years to end a devastating war, the traumatizing effects of which on central Europe lasted into the twentieth century, particularly since there was no hope of victory against his foreign adversaries from the very moment he came into power?
BUFFALO, NEW YORK IS ENJOYING A RESURGENCE, AND HAS BECOME A RECOMMENDED TRAVEL DESTINATION. THIS BOOK TELLS THE STORY OF HOW IT GOT HERE. In a sweeping narrative that speaks to the serious student of urban studies as well as the general reader, Mark Goldman tells the story of twentieth-century Buffalo, New York. Goldman covers all of the major developments: - The rise and decline of the city's downtown and ethnic neighborhoods - The impact of racial change and suburbanization - The role and function of the arts in the life of the community - Urban politics, urban design, and city planning While describing the changes that so drastically altered the form, function, and character of the city, Goldman, through detailed descriptions of special people and special places, gives a sense of intimacy and immediacy to these otherwise impersonal historical forces. City on the Edge unflinchingly documents and describes how Buffalo has been battered by the tides of history. But it also describes the unique characteristics that have encouraged an innovative cultural climate, including Buffalo's dynamic survival instinct that continues to lead to a surprisingly and inspiringly high quality of community life. Finally, it offers a road map, which-if followed-could point the way to a new and exciting future for this long-troubled city.
For more than a hundred years, Buffalo was one of the world''s great industrial cities. Its grand office buildings and stately mansions overlooked a metropolis that was the eleventh largest industrial center in the United States, the third largest producer of steel, and the largest inland port. Its diverse ethnic heritage, represented by sizable enclaves of Irish, Italians, Poles, Jews, Germans, and African-Americans, gave the city a vibrant sense of community.But by the early 1970''s, all of that had changed. Unrest in the inner city had led to riots; student protests had shut down the city''s largest university; and the economy in Buffalo, as in all the "Rust Belt" cities, was crumbling as the nation entered the postindustrial age. The population was dropping, too, dramatically altering the streets and neighborhoods where the people of this aging metropolis had lived for generations. Like the Jerusalem of Jeremiah''s Lamentations, Buffalo was a dying city whose gates were desolate and whose people were embittered.It is here that Mark Goldman''s City on the Lake takes up its story. Goldman analyzes the factors that contributed to the city''s decline and describes the efforts of its leaders and citizens to restore Buffalo to its former vitality. Goldman presents the facts - like the immigration patterns in Old Buffalo and the intricate details of the city''s 1976 desegregation case - but he also introduces us to the people of Buffalo and puts the city''s history into context by interweaving it with the colorful ethnic patchwork of its day-to-day life.By the end of this careful analysis, Goldman''s narrative is one of hope. The 1980s witnessed the slow but sure calming of ethnic strife, a new mandate for quality education, and the revitalization of downtown. Goldman believes that the grandeur of Buffalo''s past will be recaptured and that Buffalonians are dedicated to building "new gates for the old city.
The fascinating story of glutamate, the neurotransmitter that controls the structure and function of the brain in health and neurological disorders. Sculptor and Destroyer tells the story of a simple, little-known molecule that became a master architect and commander of the human brain: glutamate. Upward of 90 percent of the neurons in the human brain deploy glutamate as their neurotransmitter. Other neurotransmitters can only exert their effects on brain function by subtly modifying the ongoing activity of glutamatergic neurons, but during brain development glutamate controls the growth of dendrites and the formation of synapses. In this eye-opening book, Mark Mattson explains how the neurotransmitter glutamate controls the structure and function of neuronal networks in the brain, thereby mediating the brain’s capabilities, including learning and memory, creativity, and imagination. Mattson also delves deeply into the dark side of glutamate, which he calls the “destroyer” side. He shows how relatively subtle aberrancies in the activity of neurons that deploy glutamate may result in behavioral disorders ranging from autism and schizophrenia to chronic anxiety and depression. More dramatically, he describes how glutamate can excite neurons to death, a process that occurs in epilepsy and stroke and, perhaps even more insidiously, in Alzheimer’s disease, Parkinson’s disease, ALS, and Huntington’s disease. Sculptor and Destroyer concludes with a perspective on how knowledge of glutamate’s roles in neuroplasticity might be applied to the optimization of brain health throughout our lives. Written in engaging, approachable prose, Sculptor and Destroyer will be of interest to anyone in the fields of neuroscience, neurology, psychiatry, and psychology, as well as to anyone with a curiosity about the human brain.
In 1901 Buffalo was the national symbol of the country's optimism, pride, and braggadocio. Toward the close of the century, it epitomizes the sense of economic and demographic crisis prevalent in American industrial cities. High Hopes analyzes and interprets the historical forces—external and internal— that have shaped New York's second largest city. It examines the historical shifts that have served as a catalyst in Buffalo's growth, charting the city's evolution from a small frontier community through its development as a major commercial center and its emergence and eventual decline as a significant industrial metropolis. Mark Goldman looks at the detailed patterns of local daily life from the settlement of the village in the early nineteenth century to the tragedy of Love Canal. In the process, he covers a wide range of topics, including work, ethnicity, family and community life, class structure, and values and beliefs. By bringing to bear on the events and developments that have shaped Buffalo a broad range of subjects and ideas, Goldman helps readers to understand the vast array of complex forces at work in the historical development of all American cities.
Offering a state-of-the-art, authoritative summary of the most relevant scientific and clinical advances in the field, Principles and Practice of Movement Disorders provides the expert guidance you need to diagnose and manage the full range of these challenging conditions. Superb summary tables, a large video library, and a new, easy-to-navigate format help you find information quickly and apply it in your practice. Based on the authors’ popular Aspen Course of Movement Disorders in conjunction with the International Parkinson and Movement Disorder Society, this 3rd Edition is an indispensable resource for movement disorder specialists, general neurologists, and neurology residents. Explores all facets of movement disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. Provides the essential information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Reflects recent advances in areas such as the genetics of Parkinsonian and other movement disorders, diagnostic brain imaging, new surgical approaches to patients with movement disorders, and new treatment guidelines for conditions such as restless legs syndrome. Features a reader-friendly, full-color format, with plentiful diagrams, photographs, and tables. Includes access to several hundred updated, professional-quality video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses.
Through four editions, Cummings Otolaryngology has been the world's most trusted source for comprehensive guidance on all facets of head and neck surgery. This 5th Edition - edited by Paul W. Flint, Bruce H. Haughey, Valerie J. Lund, John K. Niparko, Mark A. Richardson, K. Thomas Robbins, and J. Regan Thomas – equips you to implement all the newest discoveries, techniques, and technologies that are shaping patient outcomes. You'll find new chapters on benign neoplasms, endoscopic DCR, head and neck ultrasound, and trends in surgical technology... a new section on rhinology... and coverage of hot topics such as Botox. Plus, your purchase includes access to the complete contents of this encyclopedic reference online, with video clips of key index cases! Overcome virtually any clinical challenge with detailed, expert coverage of every area of head and neck surgery, authored by hundreds of leading luminaries in the field. See clinical problems as they present in practice with 3,200 images - many new to this edition. Consult the complete contents of this encyclopedic reference online, with video clips of key index cases! Stay current with new chapters on benign neoplasms, endoscopic DCR, head and neck ultrasound, and trends in surgical technology... a new section on rhinology... and coverage of hot topics including Botox. Get fresh perspectives from a new editorial board and many new contributors. Find what you need faster through a streamlined format, reorganized chapters, and a color design that expedites reference.
The only reference available that synthesizes this vast subspecialty into a single trustworthy resource, Cornea, 5th Edition, provides state-of-the-art coverage of the expanding range of contemporary corneal surgery, new diagnostic and imaging technologies, and medical management of corneal and external disease as well as ocular surface disease. Drs. Mark J. Mannis, Edward J. Holland, and a team of more than 200 global experts keep you up to date with both common and more obscure diseases and disorders and the best route to effective treatment and management, making this two-volume text a must-have resource for residents and fellows, general ophthalmologists, and seasoned cornea specialists. Features more than 2,300 exceptionally clear illustrations, diagnostic images, and step-by-step surgical photographs that offer superb visual guidance. Contains 14 new chapters, including Nanothin DSAEK, Aqueous Deficiency Dry Eye Syndrome, Evaluation of Recurrent Corneal Erosions, Evaluation of the Corneal Ulcer, Contemporary Approaches to the Biosynthetic Cornea, and Topography Guided Photorefractive Keratectomy, and more. Includes more than 80 video clips of current corneal surgery techniques, including new clips of the application of cryopreserved amniotic membrane in the treatment of acute stevens , penetrating keratoplasty, DM rupture management in STALK and in the keratonconus patient, and KAMRA corneal inlay implantation. Covers the latest developments in ocular surface transplantation, including new chapters on Conjunctival Limbal Autograft (CLAU); Living Related Conjunctival Limbal Allograft (Lr-CLAL); Keratolimbal Allograft; Cultivated Limbal Epithelial Transplantation; Simple Limbal Epithelial Transplantation; and Outcomes of Ocular Surface Transplantation. Provides key point overviews in each chapter that offer easier access to crucial information.
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