Appropriate for a one-semester undergraduate or first-year graduate course, this text introduces the quantitative treatment of chemical reaction engineering. It covers both homogeneous and heterogeneous reacting systems and examines chemical reaction engineering as well as chemical reactor engineering. Each chapter contains numerous worked-out problems and real-world vignettes involving commercial applications, a feature widely praised by reviewers and teachers. 2003 edition.
Through four editions, Cummings Otolaryngology has been the world's most trusted source for comprehensive guidance on all facets of head and neck surgery. This 5th Edition - edited by Paul W. Flint, Bruce H. Haughey, Valerie J. Lund, John K. Niparko, Mark A. Richardson, K. Thomas Robbins, and J. Regan Thomas – equips you to implement all the newest discoveries, techniques, and technologies that are shaping patient outcomes. You'll find new chapters on benign neoplasms, endoscopic DCR, head and neck ultrasound, and trends in surgical technology... a new section on rhinology... and coverage of hot topics such as Botox. Plus, your purchase includes access to the complete contents of this encyclopedic reference online, with video clips of key index cases! Overcome virtually any clinical challenge with detailed, expert coverage of every area of head and neck surgery, authored by hundreds of leading luminaries in the field. See clinical problems as they present in practice with 3,200 images - many new to this edition. Consult the complete contents of this encyclopedic reference online, with video clips of key index cases! Stay current with new chapters on benign neoplasms, endoscopic DCR, head and neck ultrasound, and trends in surgical technology... a new section on rhinology... and coverage of hot topics including Botox. Get fresh perspectives from a new editorial board and many new contributors. Find what you need faster through a streamlined format, reorganized chapters, and a color design that expedites reference.
Mark Twain's letters for 1874 and 1875 encompass one of his most productive and rewarding periods as author, husband and father, and man of property. He completed the writing of The Adventures of Tom Sawyer, published the major collection Sketches, New and Old, became a leading contributor to the Atlantic Monthly, and turned The Gilded Age, the novel he had previously coauthored with Charles Dudley Warner, into one of the most popular comedies of the nineteenth-century American stage. His personal life also was gratifying, unmarred by the family tragedies that had darkened the earlier years of the decade. He and his wife welcomed a second healthy daughter and moved into the showplace home in Hartford, Connecticut, that they occupied happily for the next sixteen years. All of these accomplishments and events are vividly captured, in Mark Twain's inimitable language and with his unmatched humor, in letters to family and friends, among them some of the leading writers of the day. The comprehensive editorial annotation supplies the historical and social context that helps make these letters as fresh and immediate to a modern audience as they were to their original readers. This volume is the sixth in the only complete edition of Mark Twain's letters ever attempted. The 348 letters it contains, many of them never before published, have been meticulously transcribed, either from the original manuscripts (when extant) or from the most reliable sources now available. They have been thoroughly annotated and indexed and are supplemented by genealogical charts, contemporary notices of Mark Twain and his works, and photographs of him, his family, and his friends.
This text introduces the quantitative treatment of differential equations arising from modeling physical phenomena in chemical engineering. Coverage includes recent topics such as ODE-IVPs, emphasizing numerical methods and modeling of 1984-era commercial mathematical software.
The goal of this book is to provide a current overview of the impacts of climate change on tropical forests, to investigate past, present, and future climatic influences on the ecosystems with the highest biodiversity on the planet.Tropical Rainforest Responses to Climatic Change will be the first book to examine how tropical rain forest ecology is altered by climate change, rather than simply seeing how plant communities were altered. Shifting the emphasis onto ecological processes e.g. how diversity is structured by climate and the subsequent impact on tropical forest ecology, provides the reader with a more comprehensive coverage. A major theme of this book that emerges progressively is the interaction between humans, climate and forest ecology. While numerous books have appeared dealing with forest fragmentation and conservation, none have explicitly explored the long term occupation of tropical systems, the influence of fire and the future climatic effects of deforestation, coupled with anthropogenic emissions. Incorporating modelling of past and future systems paves the way for a discussion of conservation from a climatic perspective, rather than the usual plea to stop logging.
Trusted for decades by Physical Therapy students as well as experienced therapists who want to improve their knowledge, Tecklin’s Pediatric Physical Therapy provides a comprehensive and logical overview of some of the most common pediatric physical therapy diagnoses. This straightforward approach presents basic medical information regarding common clinical diagnostic categories followed by coverage of physical therapy examination, intervention and special considerations within each diagnostic group. Content in this 6th Edition has been thoroughly updated and reorganized to help prepare students for today’s clinical challenges, accompanied by case studies and interactive features that reinforce understanding and instill the clinical decision-making skills essential to successful practice.
The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage. This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries. - Updates to all chapters, including new examples and references - Chapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the book - Chapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistry - Chapter 3 (Receptors): Drug-receptor interactions, cation-p and halogen bonding; atropisomers; case history of the insomnia drug suvorexant - Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesis - Chapter 5 (Enzyme Inhibition and Inactivation): New case histories: - for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib - for transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazid - for slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptin - Chapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examples - Chapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolites - Chapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates
Climatologist, Lonnie Thompson has based his career and life on the highest and most remote ice caps along the equator in search of clues to the history of climate change. He collects ice cores that provide detailed information about climate history.
In the decades following the Civil War--as industrialization, urbanization, and economic expansion increasingly reshaped the landscape--many Americans began seeking adventure and aesthetic gratification through avian pursuits. By the turn of the century, hundreds of thousands of middle-and upper-class devotees were rushing to join Audubon societies, purchase field guides, and keep records of the species they encountered in the wild. Mark Barrow vividly reconstructs this story not only through the experiences of birdwatchers, collectors, conservationists, and taxidermists, but also through those of a relatively new breed of bird enthusiast: the technically oriented ornithologist. In exploring how ornithologists struggled to forge a discipline and profession amidst an explosion of popular interest in natural history, A Passion for Birds provides the first book-length history of American ornithology from the death of John James Audubon to the Second World War. Barrow shows how efforts to form a scientific community distinct from popular birders met with only partial success. The founding of the American Ornithologists' Union in 1883 and the subsequent expansion of formal educational and employment opportunities in ornithology marked important milestones in this campaign. Yet by the middle of the twentieth century, when ornithology had finally achieved the status of a modern profession, its practitioners remained dependent on the services of birdwatchers and other amateur enthusiasts. Environmental issues also loom large in Barrow's account as he traces areas of both cooperation and conflict between ornithologists and wildlife conservationists. Recounting a colorful story based on the interactions among a wide variety of bird-lovers, this book will interest historians of science, environmental historians, ornithologists, birdwatchers, and anyone curious about the historical roots of today's birding boom.
The first history of the dramatic civil rights battles fought by the National Association for the Advancement of Colored People (NAACP) in the 1920s, struggles that paved the way for advances made in the 1950s and 1960s.
Distilling all of the most important content from Dr. Donald L. Resnick's highly esteemed, five-volume Diagnosis of Bone and Joint Disorders into a single, concise source, Bone and Joint Imaging, 4th Edition focuses on the specific, state-of-the-art musculoskeletal imaging and interpretation knowledge practitioners need today. This highly anticipated new edition has been fully revised from cover to cover for a remarkably thorough, yet focused and pragmatic, source of clinical guidance. Dr. Resnick's carefully chosen editorial team, Drs. Jon A. Jacobson, Christine B. Chung, Mini N. Pathria (all former Resnick fellows) and Mark J. Kransdorf (co-author of the previous edition), are well-equipped to expertly address the many recent changes in musculoskeletal radiology since the previous edition. Authoritative, easy-to-read text and more than 3,800 exquisite images demonstrate every principle and capture the characteristic presentation of the wide range of disorders you're most likely to encounter in everyday practice. - Features a newly revised, streamlined organization with easy-to-digest sections on infection; trauma; osteoarticular, nerve, and muscle derangements; arthropathy; systemic diseases (metabolic, endocrine, hematologic, and connective tissue); tumors; interventional radiology; post-operative radiology; and pediatric imaging. - Provides more than 2,100 outstanding images (1,300 are new) that depict important concepts, techniques, and findings in musculoskeletal imaging. - Discusses the full range of diagnostic modalities, including advanced imaging methods and techniques and expanded content on MRI and ultrasound. - Covers key introductory material on basic science, diagnostic techniques, imaging, and interventional procedures. - A highly efficient review source for residency and radiology board examinations, as well as an indispensable reference for clinical practice. - A highly efficient review source for residency and radiology board examinations, as well as an indispensable reference for clinical practice. - Any additional digital ancillary content may publish up to 6 weeks following the publication date.
As the irreversible effects of glaucoma can lead to blindness, there is high demand for early diagnosis and an ongoing need for practitioners to adopt new and evolving medical and surgical treatment options to improve patient outcomes. Glaucoma, Second Edition is the most comprehensive resource in the field delivering expert guidance for the most timely and effective diagnosis and treatment of glaucoma – aimed at specialists, fellows and general ophthalmologists. More than 300 contributors from six continents provide a truly global perspective and explore new approaches in this user friendly reference which has been updated with enhanced images, more spotlights, new videos, and more. - Get all the accuracy, expertise, and dependability you could ask for from leading specialists across six continents, for expert guidance and a fresh understanding of the subject. - Develop a thorough, clinically relevant understanding of all aspects of adult and pediatric glaucoma in Volume One, and the latest diagnostic imaging techniques including ultrasound biomicroscopy and optical coherence tomography. - Stay at the forefront of your field with 10 brand new chapters on trending topics including: new surgical approaches such as trabeculotomy and canaloplasty; glaucoma implications in cataract and ocular surface disease; and, updates in the cost-effectiveness of medical management. - Avoid pitfalls and achieve the best outcomes thanks to more than 40 brand new spotlight commentaries from key leaders providing added insight, tips and pearls of wisdom across varying hot topics and advances in the field. - Refine and improve your surgical skills by watching over 50 video clips depicting the latest techniques and procedures including: new trabeculectomy methods, needling, implants, valve complications, and more. - Prevent and plan for complications in advance by examining over 1,600 illustrations, photos and graphics (1,250 in color) capturing essential diagnostics techniques, imaging methods and surgical approaches. - Grasp each procedure and review key steps quickly with chapter summary boxes that provide at-a-glance quick comprehension of the key take away points. - Broaden your surgical repertoire with the latest surgical techniques - such as trabeculectomy, gonio-surgery, combined surgeries, and implant procedures - in Volume Two. - Glean all essential, up-to-date, need-to-know information about stem cell research, gene transfer, and implants. - Find answers fast thanks to a well-organized, user-friendly full-color layout. - eBook version included with purchase.
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