Explains the tools and techniques of scientific investigators and discusses the details of some of the most sensational crimes of the twentieth century in Germany, the United States, and Canada.
Mark Benecke provides an entertaining investigation into the biological meaning of life and death and the prospects for extending human longevity, or even achieving immortality. Discussing the biological fundamentals of why death exists as well as the various ways humans cope with a finite life span, Benecke looks at alternative ways for extending our lives through such technologies as cloning, organ and brain transplantation, and live cell therapy. Maintaining a skeptical attitude to many of the claims and counterclaims made by countless experts, Benecke has written a book that both challenges and informs.
«The images are sharp and beautiful, and when I saw a couple of skulls which have a shape our brain interprets as a smile, I had to smile along with them. For everything to be at rest and truly be in peace is something I've rarely seen captured so poetically, organically and lovingly as in this book. Enjoy your time discovering the photographs in this book.» Mark Benecke, Ph.D. «Fabian Haas has dedicated himself to this natural phenomenon, life and death, and approached it with thousands of photos on his safari in the Kenya wilderness. Moments of this safari to the end of life have been selected in this book, a tribute to past and future life.» Ulrich Werner Schulze
The new, therapeutically-focused Botulinum Toxin presents comprehensive, cross-disciplinary guidance on current practices, covering more than 100 non-cosmetic conditions that occur in neurology, physical medicine and rehabilitation, pain medicine, ophthalmology, gastroenterology, urology, orthopedics, and surgery. International contributors review the current understanding of the biology and cellular mechanisms along with relevant research so you can easily apply them to the pathophysiology of the numerous disorders that botulinum toxin is used to treat—such as botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing. With discussions of the latest in approved treatment practices as well as new and emerging uses, you’ll get in-depth management guidance on the application of the toxin. Provides clinical applications of botulinum toxin for over 100 disorders for immediate access and easy reference during practice and treatment. Covers a broad array of hot topics, including botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing. Focuses on approved uses with expert advice on thoroughly tested applications but also discusses new and emerging applications to expose you to additional treatment options. Presents the most comprehensive and up-to-date material available so you get all the information you need from this one resource. Offers the cross-disciplinary guidance of the best world-class expertise through an authoritative, international group of authors who demonstrate the applications of botulinum toxin across various specialties.
Electromyography (EMG) is a technique for evaluating and recording the electrical activity produced by nerves and muscles. Interpreting EMG is a mandatory skill for neurologists and rehabilitation specialists. This textbook provides the reader with a detailed discussion of the concepts and principles underlying electrodiagnostic medicine. It is written for an audience without pre-existing knowledge in this discipline, including beginner technicians and physicians in training. It is an ideal review for seasoned practitioners and those preparing for board examinations. It begins with a review of the foundational sciences and works through the field in twenty chapters, including a large number of case studies demonstrating correct application and interpretation. Appendices of information frequently required in the EMG laboratory, such as Nerve Conduction Study techniques and their age-related normal values, anatomic regions assessed by each NCS and needle EMG studies, safety issues, and other important topics, are also included.
This is the third book on material studies in this series on medieval Novgorod and its territory, and deals with a substantial body of animal bones that has been recovered over the last decade. The zooarchaeological evidence is discussed by the editor and a number of other British and Russian specialists looking at the remains of mammals, birds and fish. Topics discussed include diet, butchery practices, the exploitation of fur and skins, mortality patterns of mammals, and metrical analyses of a wide range of species. Detailed data sets are provided to enable the reader to make comparisons with their own research, but the book is also suitable for those with a more general interest in medieval Russian archaeology.
Kingdoms, Empires, and Domains explores the history of the idea that there is more to the living world than plants and animals. Progressing chronologically through philosophical, religious, literary, and other pre-scientific traditions, leading molecular systematist Mark A. Ragan traces how transgressive creatures such as sponges, corals, algae, fungi, and diverse microscopic beings have been described, categorized, and understood throughout history. The book also explores how the concept of a "third kingdom of life" evolved within the fields of scientific botany and zoology, and continues to evolve up to the present day.
Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters. This book: Provides a comprehensive account of inference techniques in systems biology. Introduces classical and Bayesian statistical methods for complex systems. Explores networks and graphical modeling as well as a wide range of statistical models for dynamical systems. Discusses various applications for statistical systems biology, such as gene regulation and signal transduction. Features statistical data analysis on numerous technologies, including metabolic and transcriptomic technologies. Presents an in-depth presentation of reverse engineering approaches. Provides colour illustrations to explain key concepts. This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field.
In 1949 Bavaria was not only the largest and best known but also the poorest, most agricultural, and most industrially backward region of Germany. It was further its most politically conservative region. The largest political party in Bavaria was the Christian Social Union (CSU), an extremely conservative, even reactionary, regional party. In the ensuing twenty years, the leaders of the CSU's small liberal wing (in particular Franz Josef Strauss, long-time party chair and the most colorful and polarizing politician in postwar Germany) broke with the anti-industrial traditions of Bavarian Catholic politics and made themselves useful to industry. With tactical brilliance the politicians pursued their individual political ambitions, rather than a coherent modernization strategy, which, by 1969, had turned Bavaria into a prosperous Land, the center of Germany's new aerospace, defense, and energy industries, with a disproportionate share of its research institutes.
- A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology. - International list of contributors including the leading workers in the field. - Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care. - A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology. - International list of contributors including the leading workers in the field. - Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.
A groundbreaking history of early America that shows how Boston built and sustained an independent city-state in New England before being folded into the United States In the vaunted annals of America’s founding, Boston has long been held up as an exemplary “city upon a hill” and the “cradle of liberty” for an independent United States. Wresting this revered metropolis from these misleading, tired clichés, The City-State of Boston highlights Boston’s overlooked past as an autonomous city-state, and in doing so, offers a pathbreaking and brilliant new history of early America. Following Boston’s development over three centuries, Mark Peterson discusses how this self-governing Atlantic trading center began as a refuge from Britain’s Stuart monarchs and how—through its bargain with the slave trade and ratification of the Constitution—it would tragically lose integrity and autonomy as it became incorporated into the greater United States. The City-State of Boston peels away layers of myth to offer a startlingly fresh understanding of this iconic urban center.
A minute-by-minute and day-by-day account of the elite 101st Airborne’s daring parachute landing behind enemy lines at Normandy is accompanied by firsthand accounts from Airborne veterans and forty incredible, previously unknown (let alone published) color photos of the “Screaming Eagles” at Normandy and in Great Britain prior to the invasion. Accompanying these remarkable D-Day color Kodachromes—which were unearthed in the attic of an Army doctor’s daughter—are more than two hundred black-and-white photographs from 101st survivors and the author’s own private collection. This is an unprecedented look at an elite fighting force during one of the last century’s most crucial moments.
This book is the first detailed discussion of the impact of the First World War on English theology. Assessing the close relationships between English and German theologians before the First World War, Chapman then explores developments throughout the war. A series of case studies make use of a large amount of unpublished material, showing how some theologians sought to maintain relationships with their German colleagues, while others, especially from a more Anglo-Catholic perspective, used the war as an opportunity to distance themselves from the liberal theology which was beginning to dominate the universities before the war. The increasing animosity between Britain and Germany meant that relations were never healed. English theology became increasingly insular, dividing between a more home-grown variety of liberalism and an ascendant Anglo-Catholicism. Consequently, this book offers useful insights into the development of theology in the twentieth century and will be of keen interest to scholars and students of the history of theology.
Examining local politics in three Japanese domains (Yonezawa, Tokushima, and Hirosaki), this book shows how warlords (daimyo) and their samurai adapted the theory and practice of warrior rule to the peacetime challenges of demographic change and rapid economic growth in the mid-Tokugawa period. The author has a dual purpose. The first is to examine the impact of shogunate/domain relations on warlord legitimacy. Although the shogunate had supreme power in foreign and military affairs, it left much of civil law in the hands of warlords. In this civil realm, Japan resembled a federal union (or "compound state"), with the warlords as semi-independent sovereigns, rather than a unified kingdom with the shogunate as sovereign. The warlords were thus both vassals of the shogun and independent lords. In the process of his analysis, the author puts forward a new theory of warlord legitimacy in order to explain the persistence of their autonomy in civil affairs. The second purpose is to examine the quantitative dimension of warlord rule. Daimyo, the author argues, struggled against both economic and demographic pressures. It is in these struggles that domains manifested most clearly their autonomy, developing distinctive regional solutions to the problems of protoindustrialization and peasant depopulation. In formulating strategies to promote and control economic growth and to increase the peasant population, domains drew heavily on their claims to semisovereign authority and developed policies that anticipated practices of the Meiji state.
A compelling evolutionary narrative that reveals how human civilization follows the same ecological rules that shape all life on Earth Offering a bold new understanding of who we are, where we came from, and where we are going, noted ecologist Mark Bertness argues that human beings and their civilization are the products of the same self-organization, evolutionary adaptation, and natural selection processes that have created all other life on Earth. Bertness follows the evolutionary process from the primordial soup of two billion years ago through today, exploring the ways opposing forces of competition and cooperation have led to current assemblages of people, animals, and plants. Bertness's thoughtful examination of human history from the perspective of natural history provides new insights about why and how civilization developed as it has and explores how humans, as a species, might have to consciously overrule our evolutionary drivers to survive future challenges.
Ultrasound-Guided Chemodenervation Procedures provides a comprehensive multimedia approach to neurotoxin therapy using ultrasound. This combined text/atlas offers a complete review of toxin therapy, both current indications and emerging applications, as well as a detailed review of ultrasound technology and ultrasound guidance techniques for botulinum toxin injections and nerve blocks. The work also includes a detailed anatomic and pictorial atlas, which will be invaluable to clinicians performing procedures with or without ultrasound guidance. The text section of the book is a reference manual, covering conditions and indications, chemodenervation agents, and ultrasound basics including essential physics, machine settings, artifacts, scanning techniques, and procedural guidance techniques. The illustrated atlas sections offer a stunning visual roadmap for understanding ultrasound anatomy, localizing muscles, and safely and successfully performing chemodenervation procedures. Features of Ultrasound-Guided Chemodenervation Procedures include: More than 1,300 clinical pictures, anatomical drawings, and ultrasound stills Practical yet comprehensive-an indispensable print and electronic reference for clinicians Review of ultrasound technology, techniques, and clinical applications for chemodenervation Review of clinical indications and emerging uses of botulinum toxin
Might people one day live for ever? Would they want to? What sense can be made of ideas commonly referred to in terms of an 'afterlife'? What about notions of Heaven and Hell, of Purgatory and reincarnation? And in what sort of state are human beings expected to be during this 'afterlife' - immortal souls or resurrected bodies (and does either notion make sense)? What about the fact that any 'afterlife' concerns not just the fate of individuals but of society ('communion of saints') and even the physical universe itself? This book tries to survey some of the existing arguments about life 'after' death, with chapters on material from Christian tradition (particularly the New Testament and the Early Church) and from the philosophy of religion. It then attempts to reach its own conclusions, drawing on Kant and Barth in order to suggest that death is to be overcome rather than survived.
The monograph series Oxford Studies in Medieval Literature and Culture showcases the plurilingual and multicultural quality of medieval literature and actively seeks to promote research that not only focuses on the array of subjects medievalists now pursue—in literature, theology, and philosophy, in social, political, jurisprudential, and intellectual history, the history of art, and the history of science—but also that combines these subjects productively. It offers innovative studies on topics that may include, but are not limited to, manuscript and book history; languages and literatures of the global Middle Ages; race and the post-colonial; the digital humanities, media and performance; music; medicine; the history of affect and the emotions; the literature and practices of devotion; the theory and history of gender and sexuality, ecocriticism and the environment; theories of aesthetics; medievalism. Meditating about death and the afterlife was one of the most important techniques that Christian societies in medieval and early modern Europe had at their disposal for developing a sense of individual selfhood. Believers who regularly and systematically reflected on the inevitability of death and the certainty of eternal punishment in hell or reward in heaven would acquire an understanding of themselves as a unique persons defined by their moral actions; they would also learn to discipline themselves by feeling remorse for their sins, doing penance, and cultivating a permanent vigilance over their future thoughts and deeds. This book covers a crucial period in the formation and transformation of the technique of meditating on death: from the thirteenth century, when a practice that had mainly been the preserve of a monastic elite began to be more widely disseminated among all segments of Christian society, to the sixteenth, when the Protestant Reformation transformed the technique of spiritual exercise into a bible-based mindfulness that avoided the stigma of works piety. It discusses the textual instructions for meditation as well as the theories and beliefs and doctrines that lay behind them; the sources are Latin and vernacular and enjoyed widespread circulation in Roman Christian and Protestant Europe during the period under consideration.
Data, technology and insights have forever changed the public relations and corporate communications function. Failure to adapt is more a matter of willingness than inability. Now, technology, data and insights inform more meaningful objectives and elevate performance evaluation. The result is a positive return on PR investment, reduced reputational risk and optimal efficiency. By ignoring these essential assets, PR professionals risk losing executive attention and organizational investment. While "building buzz" or "breaking through the media clutter" may have been adequate measures of success in the past, the top executives who fund and evaluate corporate communications expect much more, including a quantifiable and positive return on PR investment. Leaders assume that corporate communications and PR professionals already understand the fundamentals of business, and they expect an ability to contextualize PR objectives, outputs and outcomes in the language of business. PR Technology, Data and Insights helps communications professionals understand the purpose-built technologies, data assets and actionable insights available to them while sharing best practices to apply these assets for improved PR performance over time, versus objectives and against competitors. Using case studies from industries as varied as financial services, technology, travel, automotive and more, along with best practice examples from Adobe, Mastercard, Southwest, Ford and other world class organizations, PR Technology, Data and Insights shows professional communicators how to optimize technology, lead with data, quantify PR's ability to convert public relations outputs to business outcomes, and deliver insights that empower executive decision-making.
A comprehensive survey of the state of current practice, this new edition of Brain Stimulation Therapies for Clinicians provides thoroughly updated information on the growing list of electrical stimulation therapies now in use or under study, including electroconvulsive therapy (ECT), vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS), deep brain stimulation (DBS), cortical stimulation (CS), and transcranial direct current stimulation (TDCS), as well as new coverage of promising treatments such as low intensity focused ultrasound pulsation (LIFUP) and temporal interference stimulation (TI). After a brief course on the fundamentals of electricity and a refresher on neuroanatomy, the text explores how electricity works within biological systems before progressing to the chapters on individual therapies, which cover the history and evolution of the treatment, the techniques involved, clinical indications, side effects, and an up-to-date review of the evidence base supporting its use. The book is designed to help the reader cut through the initially daunting "alphabet soup" (e.g., ECT, TMS) by providing a clear and straightforward analysis of the prevailing techniques -- an indispensable resource for both clinicians and patients seeking in-depth knowledge of these acronyms and methods. The book's noteworthy features are many: Refinements in treatment protocols since the last edition are discussed in detail. For example, the sections on ECT cover advances such as focal electrically administered seizure therapy (FEAST) and magnetic seizure therapy (MST), while the TMS chapter covers theta burst and recent approval for obsessive-compulsive disorder. The underlying science is addressed in the initial review of electricity and physics, information that is foundational to these treatment modalities, but that clinicians do not encounter in the medical school curriculum. The section also addresses the parameters for brain stimulation and how to determine the right dose. A separate chapter is devoted to low intensity focused ultrasound pulsations (LIFUP) and temporally interfering (TI) electric fields, emerging treatments that have the potential to noninvasively stimulate focal locations deep in the brain without surgery or the implantation of hardware. The section on using DBS for treatment-resistant Parkinson's disease (PD) is thorough, authoritative, and a boon to clinicians assessing the viability and efficacy of treatment options for their PD patients. The new edition retains the amusing, but always informative sidebars highlighting the history of brain experimentation and applications of brain stimulation techniques Written in a down-to-earth, accessible style by authors at the forefront of progress in the field, Brain Stimulation Therapies for Clinicians is a rigorous, evidence based review of clinical data that focuses on what we know, what we don't know, and the strength of the evidence.
Principles and Practice of Movement Disorders provides the complete, expert guidance you need to diagnose and manage these challenging conditions. Drs. Stanley Fahn, Joseph Jankovic and Mark Hallett explore all facets of these disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. An accompanying Expert Consult website makes the content fully searchable and contains several hundred video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses. Get just the information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Find the answers you need quickly and easily thanks to a reader-friendly full-color format, with plentiful diagrams, photographs, and tables. Apply the latest advances to diagnosis and treatment of pediatric movement disorders, Parkinson disease, and much more. View the characteristic presentation of each disorder with a complete collection of professional-quality, narrated videos online. Better visualize every concept with new full-color illustrations throughout. Search the complete text online, follow links to PubMed abstracts, and download all of the illustrations, at www.expertconsult.com.
This book, cohesively written by an expert author with supreme breadth and depth of perspective on polyurethanes, provides a comprehensive overview of all aspects of the science and technology on one of the most commonly produced plastics. Covers the applications, manufacture, and markets for polyurethanes, and discusses analytical methods, reaction mechanisms, morphology, and synthetic routes Provides an up-to-date view of the current markets and trend analysis based on patent activity and updates chapters to include new research Includes two new chapters on PU recycling and PU hybrids, covering the opportunities and challenges in both
This study focuses on the uses of the grammatical concept of etymologia in primarily Latin writings from the early Middle Ages. Etymologia is a fundamental procedure and discursive strategy in the philosophy and analysis of language in early medieval Latin grammar, as well as in Biblical exegesis, encyclopedic writing, theology, and philosophy. Read through the frame of poststructuralist analysis of discourse and the philosophy of science, the procedure of the ars grammatica are interpreted as overlapping genres (commentary, glossary, encyclopedia, exegesis) which use different verbal or extraverbal criteria to explain the origins and significations of words and which establish different epistemological frames within which an etymological account of language is situated. The study also includes many translations of heretofore untranslated passages from Latin grammatical and exegetical writings.
Progress in Motor Control, Volume Two, features 12 chapters by internationally known researchers in the field of motor control. Comprehensive and up to date, the reference reflects the spirit of the great Nikolai Bernstein, one of the founders of the area now defined as motor control and a significant contributor to the structure-function controversy. Progress in Motor Control, Volume Two, preserves many of the features that made the first volume a state-of-the-art reference and presents these new features: -A reader-friendly design -More than 170 figures to illustrate the scientific ideas expressed -Many up-to-date references to help readers find the most current research in the field Less theoretical than the first volume, this book provides readers with valuable information on these subjects: -The direct relations of the motor function to neurophysiological and/or biomechanical structures -The role of the motor cortex and other brain structures in motor control and motor learning -The multidimensional and temporal regulation of limb mechanics by spinal circuits In this unique forum, prominent motor control scientists contribute varying viewpoints on different aspects of structure-function relations. These prominent scholars include scientists from the former Soviet Union who either knew Bernstein personally or worked closely with his students, biomechanists and neurophysiologists who focus on the role of particular body structures in the movement of production, and clinicians who analyze changes in movements with children and adults with neurological disorders. The book also gives an overview of the disagreement between Ivan Pavlov and Nikolai Bernstein, which is one of the most fascinating and controversial disagreements in the history of contemporary neurophysiology. Whether you're a researcher, or graduate or postdoctoral student, Progress in Motor Control, Volume Two, thoroughly summarizes the latest motor control issues, research, and theories, and it identifies problems in need of investigation.
Cannabis: Evolution and Ethnobotany is a comprehensive, interdisciplinary exploration of the natural origins and early evolution of this famous plant, highlighting its historic role in the development of human societies. Cannabis has long been prized for the strong and durable fiber in its stalks, its edible and oil-rich seeds, and the psychoactive and medicinal compounds produced by its female flowers. The culturally valuable and often irreplaceable goods derived from cannabis deeply influenced the commercial, medical, ritual, and religious practices of cultures throughout the ages, and human desire for these commodities directed the evolution of the plant toward its contemporary varieties. As interest in cannabis grows and public debate over its many uses rises, this book will help us understand why humanity continues to rely on this plant and adapts it to suit our needs.
With eight new chapters and 130 pages of fresh material, this second edition covers a wide range of topics, including movement disorders and current theories of motor control and co-ordination.
The successful launch of viable MEMs product hinges on MEMS reliability, the reliability and qualification for MEMs based products is not widely understood. Companies that have a deep understanding of MEMs reliability view the information as a competitive advantage and are reluctant to share it. MEMs Reliability, focuses on the reliability and manufacturability of MEMS at a fundamental level by addressing process development and characterization, material property characterization, failure mechanisms and physics of failure (POF), design strategies for improving yield, design for reliability (DFR), packaging and testing.
The authors explore recent progress in theoretical & experimental studies of motor control, from the perspective of practitioners who work with patients that have motor disorders. The text also develops new approaches to motor rehabilitation.
This study of Gottfried von Strassburg discusses the narrative technique of his romance Tristan (c. 1210) against the double background of Latin rhetoric and poetics on the one hand, and the developing written vernacular tradition on the other. It argues that Gottfried's poetics represents the attempt to mediate between opposing tendencies in vernacular narrative, the one historiographic and archival, the other fictional and experimental. Verisimilitude, the res ficta quae tamen fieri potest, occupies an intermediate position between the res factae of history and the res fictae of poetry; it is on this middle ground that Gottfried situates his narrative.
Through four editions, Cummings Otolaryngology has been the world's most trusted source for comprehensive guidance on all facets of head and neck surgery. This 5th Edition - edited by Paul W. Flint, Bruce H. Haughey, Valerie J. Lund, John K. Niparko, Mark A. Richardson, K. Thomas Robbins, and J. Regan Thomas – equips you to implement all the newest discoveries, techniques, and technologies that are shaping patient outcomes. You'll find new chapters on benign neoplasms, endoscopic DCR, head and neck ultrasound, and trends in surgical technology... a new section on rhinology... and coverage of hot topics such as Botox. Plus, your purchase includes access to the complete contents of this encyclopedic reference online, with video clips of key index cases! Overcome virtually any clinical challenge with detailed, expert coverage of every area of head and neck surgery, authored by hundreds of leading luminaries in the field. See clinical problems as they present in practice with 3,200 images - many new to this edition. Consult the complete contents of this encyclopedic reference online, with video clips of key index cases! Stay current with new chapters on benign neoplasms, endoscopic DCR, head and neck ultrasound, and trends in surgical technology... a new section on rhinology... and coverage of hot topics including Botox. Get fresh perspectives from a new editorial board and many new contributors. Find what you need faster through a streamlined format, reorganized chapters, and a color design that expedites reference.
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