Nearly forty years after its original publication, one of the most influential textbooks on modern pain management is available again for today’s generation, in a unique and enhanced edition. Now complemented by expert, chapter-by-chapter commentaries from leading authorities on psychologically-oriented pain management and pain-associated disability, Fordyce’s Behavioral Methods for Chronic Pain and Illness blends Dr. Fordyce’s pioneering behavioral concepts with modern research and clinical practice. This innovative title is ideal for clinicians and researchers involved in the multidisciplinary assessment, treatment, and management of pain and pain-associated disorders, as well as anyone interested in behavioral approaches to chronic pain and illness.
Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) provides the most recent summary of toxicity data relevant to mammals, birds, reptiles, and amphibians, and provides values for use in risk assessment applications. Predicting the bioaccumulation of PFAS in terrestrial wildlife (including humans) has proven to be extremely complex. As a group, PFAS act differently than traditional non-ionic organic molecules, where PFAS can break down and reform, whereas some are demonstrated to be extremely persistent. Where sufficient data are provided, this book establishes toxicity reference values (TRVs), which are derived to assist in characterizing environmental sources of contamination and making risk-based decisions. Features: Provides toxicity reference values (TRVs) for vertebrates (mammals, birds, amphibians) for PFAS, where sufficient data are available, and includes objective supporting background information. Assigns a level of confidence to each TRV to provide the risk assessor with an understanding of the relative uncertainty associated with each value. Presents toxicity data in the formats of scatter diagrams and tables for quick review and assessment. Provides TRVs relevant for screening and decision making This book serves as a useful aid for risk assessors and managers in those industries that have sites contaminated with PFAS, consultants tasked with evaluating risks at such sites, and staff at regulatory agencies at various governmental levels, who need to know how much contamination is considered safe for wildlife. It will also appeal to researchers with an interest in filling the gaps in the current toxicological data for PFAS exposure.
An essential experience of being a baseball fan is the hopeful anticipation of seeing the hometown nine make a run at winning the World Series. In Paths to Glory, Mark L. Armour and Daniel R. Levitt review how teams build themselves up into winners. What makes a winning team like the 1900 Brooklyn Superbas or the 1917 White Sox or the 1997 Florida Marlins? And how are these teams different? What makes each championship team a unique product of its time? Armour and Levitt provide the historical context to show how the sport's business side has changed dramatically but its competitive environment remains the same. Utilizing new statistics to evaluate a player's value and career patterns, Armour and Levitt explore the teams that took risks, created their own opportunities, and changed the game. How did the Washington Senators achieve the unthinkable and blow past Babe Ruth's Yankees in 1924 and 1925? How did the 1965 Minnesota Twins quickly rise to the top and why did they just as suddenly fall? Did Charlie Finley assemble the last old-fashioned championship team before free agency, or was the Moustache Gang another example of winning by building from within? Why did the star-laden Red Sox of the 1930s keep falling short? In exploring these teams and more, Armour and Levitt analyze the players, the managers, and the executives who built teams to win and then lived with the consequences.
In the summer of 1998 two of baseball leading sluggers, Mark McGwire and Sammy Sosa, embarked on a race to break Babe Ruth’s single season home run record. The nation was transfixed as Sosa went on to hit 66 home runs, and McGwire 70. Three years later, San Francisco Giants All-Star Barry Bonds surpassed McGwire by 3 home runs in the midst of what was perhaps the greatest offensive display in baseball history. Over the next three seasons, as Bonds regularly launched mammoth shots into the San Francisco Bay, baseball players across the country were hitting home runs at unprecedented rates. For years there had been rumors that perhaps some of these players owed their success to steroids. But crowd pleasing homers were big business, and sportswriters, fans, and officials alike simply turned a blind eye. Then, in December of 2004, after more than a year of investigation, San Francisco Chronicle reporters Mark Fainaru-Wada and Lance Williams broke the story that in a federal investigation of a nutritional supplement company called BALCO, Yankees slugger Jason Giambi had admitted taking steroids. Barry Bonds was also implicated. Immediately the issue of steroids became front page news. The revelations led to Congressional hearings on baseball’s drug problems and continued to drive the effort to purge the U.S. Olympic movement of drug cheats. Now Fainaru-Wada and Williams expose for the first time the secrets of the BALCO investigation that has turned the sports world upside down. Game of Shadows: Barry Bonds, BALCO, and the Steroid Scandal That Rocked Professional by award-winning investigative journalists Mark Fainaru-Wada and Lance Williams, is a riveting narrative about the biggest doping scandal in the history of sports, and how baseball’s home run king, Barry Bonds of the San Francisco Giants, came to use steroids. Drawing on more than two years of reporting, including interviews with hundreds of people, and exclusive access to secret grand jury testimony, confidential documents, audio recordings, and more, the authors provide, for the first time, a definitive account of the shocking steroids scandal that made headlines across the country. The book traces the career of Victor Conte, founder of the BALCO laboratory, an egomaniacal former rock musician and self-proclaimed nutritionist, who set out to corrupt sports by providing athletes with “designer” steroids that would be undetectable on “state-of-the-art” doping tests. Conte gave the undetectable drugs to 28 of the world’s greatest athletes—Olympians, NFL players and baseball stars, Bonds chief among them. A separate narrative thread details the steroids use of Bonds, an immensely talented, moody player who turned to performance-enhancing drugs after Mark McGwire of the St. Louis Cardinals set a new home run record in 1998. Through his personal trainer, Bonds gained access to BALCO drugs. All of the great athletes who visited BALCO benefited tremendously—Bonds broke McGwire’s record—but many had their careers disrupted after federal investigators raided BALCO and indicted Conte. The authors trace the course of the probe, and the baffling decision of federal prosecutors to protect the elite athletes who were involved. Highlights of Game of Shadows include: Barry Bonds A look at how Bonds was driven to use performance-enhancing drugs in part by jealousy over Mark McGwire’s record-breaking 1998 season. It was shortly thereafter that Bonds—who had never used anything more performance enhancing than a protein shake from the health food store—first began using steroids. How Bonds’s weight trainer, steroid dealer Greg Anderson, arranged to meet Victor Conte before the 2001 baseball season with...
In his trademark straight-talking, no-nonsense style Mark Webber reveals his amazing life on and off the Formula One race track in Aussie Grit. Mark Webber was at the centre of one of the most captivating chapters in the history of Formula One. In 2010, while racing for Red Bull, he and his team mate Sebastian Vettel went head to head for the World Championship. There could only be one winner. Since retiring from Formula One Mark has concentrated on endurance racing, including the legendary Le Mans 24 Hour race. He hit the front pages of newspapers around the world in December 2014 when he slammed into the barricades in the final round of the FIA World Endurance Championship in South America, and was lucky to escape with his life. But the controversy of his relationship on and off the track with Vettel, who went on to win multiple world titles, has never been far beneath the surface. Here, for the first time, Webber tells the inside story of one of Formula One's most intriguing battles – it is a story that goes to the heart of why the sport is loved by millions of fans around the world. From his first taste of karting to his F1 debut in 2002, scoring Minardi's first points in three years at the Australian Grand Prix, through to his first win with Red Bull at the 2009 German Grand Prix and the year he should have been crowned World Champion. Mark Webber's journey to the top of Formula One was every bit as determined and committed as his racing. Aussie Grit is his searingly honest story. Includes a foreword by Formula One legend Sir Jackie Stewart.
Though the Civil War ended in April 1865, the conflict between Unionists and Confederates continued. The bitterness and rancor resulting from the collapse of the Confederacy spurred an ongoing cycle of hostility and bloodshed that made the Reconstruction period a violent era of transition. The violence was so pervasive that the federal government deployed units of the U.S. Army in North Carolina and other southern states to maintain law and order and protect blacks and Unionists. Bluecoats and Tar Heels: Soldiers and Civilians in Reconstruction North Carolina tells the story of the army's twelve-year occupation of North Carolina, a time of political instability and social unrest. Author Mark Bradley details the complex interaction between the federal soldiers and the North Carolina civilians during this tumultuous period. The federal troops attempted an impossible juggling act: protecting the social and political rights of the newly freed black North Carolinians while conciliating their former enemies, the ex-Confederates. The officers sought to minimize violence and unrest during the lengthy transition from war to peace, but they ultimately proved far more successful in promoting sectional reconciliation than in protecting the freedpeople. Bradley's exhaustive study examines the military efforts to stabilize the region in the face of opposition from both ordinary citizens and dangerous outlaws such as the Regulators and the Ku Klux Klan. By 1872, the widespread, organized violence that had plagued North Carolina since the close of the war had ceased, enabling the bluecoats and the ex-Confederates to participate in public rituals and social events that served as symbols of sectional reconciliation. This rapprochement has been largely forgotten, lost amidst the postbellum barrage of Lost Cause rhetoric, causing many historians to believe that the process of national reunion did not begin until after Reconstruction. Rectifying this misconception, Bluecoats and Tar Heels illuminates the U.S. Army's significant role in an understudied aspect of Civil War reconciliation.
-- Not only explains the new features of Windows .NET Server 2003, but also provides continued support for Windows 2000 administration.-- Covers changes in security, Active Directory, Microsoft Management Console, and integration with the .NET Framework, among many others changes.Windows .NET Server 2003 is the first Microsoft product that is innately affected by the company's recent Trustworthy Computing initiative. If this is successful, this will be the most stable, reliable, and dependable server OS that Microsoft has ever released. It will also feature an integrated environment with the .NET Framework and the Common Language Runtime. The Ultimate Windows .NET Server 2003 System Administrator's Guide is an essential resource for planning, deploying, and administering a Windows .NET enterprise system. The authors draw on years of experience designing and administering Windows NT and UNIX systems in order to guide you through the varied tasks involved in real-world system administration. There are detailed discussions of key Windows .NET Server administrative functions, and descriptions of many advanced tools and optional components. In addition the authors have included a comprehensive and convenient command reference.
After two years, MAKE has become one of most celebrated new magazines to hit the newsstands, and certainly one of the hottest reads. If you're just catching on to the MAKE phenomenon and wonder what you've missed, this book contains the best DIY projects from the magazine's first ten volumes -- a surefire collection of fun and challenging activities going back to MAKE's launch in early 2005. Find out why MAKE has attracted a passionate following of tech and DIY enthusiasts worldwide with one million web site visitors and a quarter of a million magazine readers. And why our podcasts consistently rank in the top-25 for computers and technology. With the Best of MAKE, you'll share the curiosity, zeal, and energy of Makers -- the citizen scientists, circuit benders, homemakers, students, automotive enthusiasts, roboticists, software developers, musicians, hackers, hobbyists, and crafters -- through this unique and inspiring assortment of DIY projects chosen by the magazine's editors. Learn to: Hack your gadgets and toys Program micontrollers to sense and react to things Take flight with rockets, planes, and other projectiles Make music from the most surprising of things Find new ways to take photos and make video Outfit yourself with the coolest tools Put together by popular demand, the Best of MAKE is the perfect gift for any maker, including current subscribers who missed early volumes of the magazine. Do you or someone you know have a passion for the magic of tinkering, hacking, and creation? Do you enjoy finding imaginative and unexpected uses for the technology and materials in your life? Then get on board with the Best of MAKE!
Recognized authorities in anesthesiology and surgical critical care present you with today's best management approaches for achieving optimal perioperative outcomes. They review the potential risks to all major organ systems by examining the incidence and significance of organ dysfunction...assessing the etiology of particular organ dysfunctions...defining the preoperative and intraoperative risk factors...and offering perioperative protection strategies to minimize potential complications. A consistent chapter format - combined with color-coded algorithms, summary tables and boxes - enable you to quickly locate specific guidance. Top evidence- and outcome-based strategies from leading world authorities enable you to avoid and manage complications. A consistent format allows you to easily and efficiently access the very latest research and clinical practice guidelines. Color-coded algorithms, as well as abundant summary tables and boxes, save you valuable time in locating the best management approaches.
This book explores the development and application of the law of treason in England across more than a thousand years, placing this legal history within a broader historical context. Describing many high-profile prosecutions and trials, the book focuses on the statutes, ordinances and customs that have at various times governed, limited and shaped this worst of crimes. It explores the reasons why treason coalesced around specific offences agreed by both the monarch and the wider political nation, why it became an essential instrument of enforcement in high politics, and why, over the past three hundred years, it has gradually fallen into disuse while remaining on the statute book. This book also considers why treason as both a word and a concept remains so potent in wider modern culture, investigating prevalent current misconceptions about what is and what is not treason. It concludes by suggesting that the abolition or 'death' of treason in the near future, while a logical next step, is by no means a foregone conclusion. The Rise and Fall of Treason in English History is a thorough academic introduction for scholars and history students, as well as general readers with an interest in British political and legal history.
Leading business consultant Williams has developed ten "lenses" to profile how people "view" race, culture and ethnicity in their world. For corporations, civic institutions, and individuals--these ten lenses provide easily accessible and recognizable profiles of people's belief systems and their influence in the workplace and in society.
For nearly 50 years, Sleisenger & Fordtran's Gastrointestinal and Liver Disease has been the go-to reference for gastroenterology and hepatology residents, fellows, physicians, and the entire GI caregiving team. Now in a fully revised 11th Edition, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with the newest techniques, technologies, and treatments for every clinical challenge you face in gastroenterology and hepatology. A logical organization, more than 1,100 full-color illustrations, and easy-to-use algorithms ensure that you'll quickly and easily find the information you need. - Features new and expanded discussions of chronic hepatitis B and C, Helicobacter pylori infection, colorectal cancer prevention through screening and surveillance, biologic agents and novel small molecules to treat and prevent recurrences of inflammatory bowel disease (IBD), gastrointestinal immune and autoimmune diseases, and more. - Offers reliable coverage of key topics such as Barrett's esophagus, gut microbiome, enteric microbiota and probiotics, fecal microbiota transplantation, and hepatic, pancreatic, and small bowel transplantation. - Provides more quick-reference algorithms that summarize clinical decision making and practical approaches to patient management. - Employs a consistent, templated, format throughout for quick retrieval of information. - Includes monthly updates online, as well as more than 20 procedural videos. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
In this entertaining homage to the golden age of the cocktail, illustrator Edward Hemingway and writer Mark Bailey present the best (and thirstiest) American writers, their favorite cocktails, true stories of their saucy escapades, and intoxicating excerpts from their literary works. It’s the perfect blend of classic cocktail recipes, literary history, and tales of the good old days of extravagant Martini lunches and delicious excess. When Algonquin Round Table legend Robert Benchley was asked if he knew that drinking was a slow death, Benchley took a sip of his cocktail and replied, “So who’s in a hurry?” Hunter S. Thompson took Muhammad Ali’s health tip to eat grapefruit every day; he just added liquor to the mix. Invited to a “come as you are” party, F. Scott Fitzgerald and his wife, Zelda, arrived in their pajamas ready for their cocktail of choice: a Gin Rickey. Forty-three classic American writers, forty-three authentic cocktail recipes, forty-three telling anecdotes about the high life, and forty-three samples of the best writing in literature –Hemingway & Bailey’s Bartending Guide to Great American Writers delivers straight-up fun.
Patient-centered care for chronic illness is founded upon the informed and activated patient, but we are not clear what this means. We must understand patients as subjects who know things and as agents who do things. Bioethics has urged us to respect patient autonomy, but it has understood this autonomy narrowly in terms of informed consent for treatment choice. In chronic illness care, the ethical and clinical challenge is to not just respect, but to promote patient autonomy, understood broadly as the patients' overall agency or capacity for action. The primary barrier to patient action in chronic illness is not clinicians dictating treatment choice, but clinicians dictating the nature of the clinical problem. The patient's perspective on clinical problems is now often added to the objective-disease perspective of clinicians as health-related quality of life (HRQL). But HRQL is merely a hybrid transitional concept between disease-focused and health-focused goals for clinical care. Truly patient-centered care requires a sense of patient-centered health that is perceived by the patient and defined in terms of the patient's vital goals. Patient action is an essential means to this patient-centered health, as well as an essential component of this health. This action is not extrinsically motivated adherence, but intrinsically motivated striving for vital goals. Modern pathophysiological medicine has trouble understanding both patient action and health. The self-moving and self-healing capacities of patients can be understood only if we understand their roots in the biological autonomy of organisms. Taking the patient as the primary perceiver and producer of health has the following policy implications: 1] Care will become patient-centered only when the patient is the primary customer of care. 2] Professional health services are not the principal source of population health, and may lead to clinical, social and cultural iatrogenic injury. 3] Social justice demands equity in health capability more than equal access to health services.
Williams has done the unthinkable and spilled the beans, identifying the "10 Fit Factors" that define a company's culture. His text provides a map to navigate the back doors and underground paths that lead to corporate success.
THE TIMES ART BOOK OF THE YEAR Named one of The Irish Times' Books of the Year for 2021 A compelling and comprehensive look at the life and art of Francis Bacon, one of the iconic painters of the twentieth century—from the Pulitzer Prize-winning authors of de Kooning: An American Master. This intimate study of the singularly private, darkly funny, eruptive man and his extraordinary art “is bejeweled with sensuous detail … the iconoclastic charm of the artist keeps the pages turning” (The Washington Post). “A definitive life of Francis Bacon ... Stevens and Swan are vivid scene setters ... Francis Bacon does justice to the contradictions of both the man and the art.” —The Boston Globe Francis Bacon created an indelible image of mankind in modern times, and played an outsized role in both twentieth century art and life—from his public emergence with his legendary Triptych 1944 (its images "so unrelievedly awful" that people fled the gallery), to his death in Madrid in 1992. Bacon was a witty free spirit and unabashed homosexual at a time when many others remained closeted, and his exploits were as unforgettable as his images. He moved among the worlds of London's Soho and East End, the literary salons of London and Paris, and the homosexual life of Tangier. Through hundreds of interviews, and extensive new research, the authors probe Bacon's childhood in Ireland (he earned his father's lasting disdain because his asthma prevented him from hunting); his increasingly open homosexuality; his early design career—never before explored in detail; the formation of his vision; his early failure as an artist; his uneasy relationship with American abstract art; and his improbable late emergence onto the international stage as one of the great visionaries of the twentieth century. In all, Francis Bacon: Revelations gives us a more complete and nuanced--and more international--portrait than ever before of this singularly private, darkly funny, eruptive man and his equally eruptive, extraordinary art. Bacon was not just an influential artist, he helped remake the twentieth-century figure.
Any man can be a father, but it takes a special person to be a dad. Chicken Soup for the Father and Son Soul takes a peak into the lives of fathers and sons, sharing the important male milestones from birth through childhood, adolescence, young adulthood, the senior years, and every step in between. This is a celebration of how fathers and sons carry each other along life's journey. Share the story of one man who didn't think much of becoming a father until the day he laid eyes on his son, and how in a matter of moments his perspective on life and being a dad had profoundly changed forever, and the touching story of a young boy who finds the father he always longed for in a special stepdad, as well as the story of the love and respect between a father-in-law and son-in-law that appears when least expected. Readers will be inspired by the stories of sons looking up to their fathers and learning by example, and fathers recollecting their own childhoods and relationships with their own dads. These insightful stories show men and boys working through the ups and downs of life, learning as they go and becoming better because of their relationship with each other. These powerful and poignant stories are written from every point of view—fathers, sons, grandfathers, mothers, and wives—everyone who has been deeply touched by the father and son relationship.
A definitive guide to the Premiership, featuring an entry for each club highlighting the players and statistics, together with the enhanced fixture list, maps and directions to the grounds of all the clubs in the Premiership.
For Republicans, the 2004 presidential election was little short of miraculous: Behind in the Electoral College tally in the days leading up to the election, behind even on the very afternoon of the vote, the Bush ticket staged a stunning comeback. The exit polls, usually so reliable, turned out to be wrong by an unprecedented 5 percent in the swing states. Conservatives argued-and the media agreed-that "moral values" had made the difference. In his new book renowned critic and political commentator Mark Crispin Miller argues that it wasn't moral values that swung the election-it was theft. While the greatest body of evidence comes from the key state of Ohio-where the Democratic staff of the House Judiciary Committee found an extraordinary onslaught of Republican-engineered vote suppression, election-day irregularities, old-fashioned intimidation tactics, and illegal counting procedures-similar practices (and occasionally worse ones) were applied in Florida, Oregon, Pennsylvania, New Mexico, Nevada, Arizona, and even New York. A huge array of anomalies, improper practices, and blatant violations of the law all, by a truly remarkable coincidence, happened to swing in the Bush ticket's favor. This pattern-not one overwhelming fraud but thousands of little ones-is, in Miller's view, the new Republican electoral strategy. This incendiary new book presents massive documentation that the election was stolen and describes the mind-set, among both the major parties and the media, that could permit it to happen again.
By assembling a host of essays that engage in interdisciplinary commentary regarding one of Western culture's most enduring artistic and socially radicalizing phenomena, this book offers a cohesive, intellectual, and often entertaining introduction to the many ways in which Springsteen continues to impact our lives by challenging our minds through his lyrics and music.
Evidence: Law and Context explains the key concepts of evidence law in England and Wales clearly and concisely, set against the backdrop of the broader political and theoretical contexts. The book focuses on the essential topics commonly found on Evidence courses, covering both criminal evidence and civil evidence. Taking a contextual approach, the authors show how wider policy debates and societal trends have impacted upon the recent evolution of the law, helping to explain how and why the law has developed. The sixth edition has been revised to include: the impacts of the COVID-19 pandemic, the introduction of the Solicitors Qualifying Examination (SQE), and updates on previous statistics on the increase in the use of ‘show pleas,’ false confessions, and miscarriages of justice, alongside a comparative perspective on how the American criminal practice has evolved along a parallel line. Learning points summarise the major principles and rules covered and practical examples are used throughout the text to give better understanding as to how the technical rules are applied in practice. Self-test questions are included in the book, helping students to test their understanding and prepare for assessment. Well written, clear, and with a logical structure throughout, it contains all the information necessary for any undergraduate evidence law module.
In this original and illuminating new study, Mark Knights reveals how the political culture of the eighteenth century grew out of earlier trends and innovations. Arguing that the period from 1675 needs to be seen as the second stage of a seventeenth-century revolution that ran on until c.1720, Representation and Misrepresentation in Later Stuart Britain charts the growth of a national political culture and traces the development of the public as an arbiter of politics. In doing so, it uncovers a crisis of public discourse and credibility, and finds a political enlightenment rooted in local and national partisan conflict. The later Stuart period was characterized by frequent elections, the lapse of pre-publication licensing, the emergence of party politics, the creation of a public debt, and ideological conflict over popular sovereignty. These factors combined to enhance the status of the 'public', not least in requiring it to make numerous acts of judgement. Contemporaries from across the political spectrum feared that the public might be misled by the misrepresentations pedalled by their rivals. Each side, and those ostensibly of no side, discerned a culture of passion, slander, libel, lies, hypocrisy, dissimulation, conspiracy, private languages, and fictions. 'Truth' appeared an ambiguous, political matter. Yet the reaction to partisanship was also creative, for it helped to construct an ideal form of political discourse. This was one based on reason rather than passion, on moderation rather than partisan zeal, on critical reading rather than credulity; and an increasing realization that these virtues arose from infrequent rather than frequent elections. Finding synergies between social, political, religious, scientific, literary, cultural, and intellectual history, Representation and Misrepresentation in Later Stuart Britain reinvigorates the debate about the emergence of 'the public sphere' in the later Stuart period.
As the adult game has increased in popularity, youth soccer has also seen significant expansion in recent years. The popularity of the youth game is set to continue. Young boy and girl players wish to emulate professional soccer stars and the professional game, often with long-term financial rewards in mind, is increasingly keen to develop young talent. Applied sports science is now a well-established feature of the adult game but the sports science that supports modern football does not translate directly into the youth game. The coaches of young players need specific information about children. Themes explored in this text include: growth of physiological systems development of motor and perceptive skills paediatric environmental physiology prevention of injury diet and nutrition youth fitness and skills training effective teaching and coaching of juniors the role of football academies. Youth Soccer: From Science to Performance blends current child-focused sports science theory with youth-specific coaching practice to help create soccer development strategies for children. It promotes knowledge and understanding in all these areas and will further professional expertise amongst coaches who wish to develop the all year round potential of youth soccer players and train the stars of the future.
Airway management is the medical process of ensuring there is an open pathway between a patient’s lungs and the outside world, as well as reducing the risk of aspiration. Airway management is a primary consideration in cardiopulmonary resuscitation, anesthesia, emergency medicine, intensive care medicine and first aid. Difficult airway (defined as more than three attempts, or taking longer than 10 minutes) is the major factor in anesthesia morbidity.
The only reference to focus on the must-know aspects of neurology for psychiatrists, Kaufman's Clinical Neurology for Psychiatrists, 9th Edition, brings you up to date with the knowledge you need to excel on the American Board of Psychiatry and Neurology and other examinations. It fully covers the exam topics you'll encounter, along with new content, high-quality illustrations, and multiple-choice questions. In addition, this book prepares you for clinical work in the 21st century. - Discusses timely, clinically-relevant topics such as chronic and acute traumatic brain injury, Alzheimer's disease, correctible causes of dementia, violence, neurologic illnesses that present with symptoms of autism, illicit drug use, stroke, migraine, Parkinson's disease, tardive dyskinesia current treatments, and more. - Includes nearly 2,000 multiple-choice questions both in print and online—all written to help you succeed on the ABPN certifying exam. - Features new content, new and improved clinical illustrations: life-like patient sketches, anatomy line drawings, CTs, MRIs, and EEGs. - Explains each condition's neurologic and psychiatric features, easily performed office and bedside examinations, appropriate tests, differential diagnosis, and management options. - Correlates neurologic illnesses with the DSM-5.
Mark Bernstein shows that much of the culture that surrounds American football, both good and bad, has its roots in the Ivy League. With their long winning streaks, distinctive traditions, and impressive victories, Ivy teams started a national obsession with football in the first decades of the twentieth century that remains alive today. In so doing they have helped develop our ideals about the role of athletics in college life.
Regulation of Securities: SEC Answer Book, Fourth Edition is your complete guide to understanding and complying with the day-to-day requirements of the federal securities laws that affect all public companies. Using a question-and-answer format similar to that which the SEC has embraced, this valuable desk reference provides concise, understandable answers to the most frequently asked compliance questions, and ready access to key statutes, regulations, and court decisions. Designed for both beginners and seasoned professionals, the volume contains approximately 1,400 pages organized in 23 self-contained chapters. Each chapter covers the basics before moving into the nuanced details, meeting the needs of those who seek a general understanding of a topic as well as those grappling directly with critical issues. Twice-yearly supplements keep the book current in this rapidly evolving field. Whether you are a lawyer, accountant, corporate executive, director or investor, youand’ll be able to quickly find concise answers to essential questions about the Dodd-Frank Act, Exchange Act registration and reporting, executive compensation disclosure, derivatives disclosure, managementand’s discussion and analysis, audit committee responsibilities, Sarbanes-Oxley, electronic filing, interactive financial data, tender offers, proxy solicitations, insider trading, going private transactions, shareholdersand’ rights, SEC investigations, criminal enforcement, securities class actions, and much more!
Hydrology is vital to human civilisations as well as to natural ecosystems, yet it has only emerged as a distinct scientific discipline during the last 50 years or so. This book reviews the development of modern hydrology primarily through the experiences of the multidisciplinary team of scientists and engineers at Wallingford, near Oxford, who have been at the forefront of many of the developments in UK hydrological research. These topics include: • The development of basic understanding through the collection of data with specialised instrumentation in experimental basins • The study of extreme flows – both floods and droughts • The role moisture in the soil • Studies of the processes controlling evaporation • Water resource studies • Modelling and prediction of the extremes of flow improved • Understanding of water quality issues • A widening recognition of the importance of an ecosystem approach • Meeting the challenges of climate change, • Data handling • Future developments in hydrology and the pressures which generate them. Readership: hydrologists in both academia and a wide range of applied fields such as civil engineering, meteorology, geography and physics, as well as advanced students in earth science, environmental science and physical geography programmes worldwide.
This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage. This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries. - Updates to all chapters, including new examples and references - Chapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the book - Chapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistry - Chapter 3 (Receptors): Drug-receptor interactions, cation-p and halogen bonding; atropisomers; case history of the insomnia drug suvorexant - Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesis - Chapter 5 (Enzyme Inhibition and Inactivation): New case histories: - for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib - for transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazid - for slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptin - Chapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examples - Chapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolites - Chapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates
*Exploits new features of Visual Studio .NET 2003 and the Oracle database 10g. (But concepts and code still apply to the earlier releases, 8i and 9i, that currently comprise most business systems). *Explains Oracle programming using both C# and VB.NET languages; provides a one-stop reference for VS.NET developers working with Oracle. *Excellent resource for J2EE programmers in environments considering moving to a .NET environment (and retaining the Oracle database).
What are the most effective tools, techniques and technologies available to coaches and sport scientists in the assessment of player and team performance? This is the first book dedicated to the assessment of performance in field sports such as soccer, rugby, hockey and lacrosse. It provides detailed and clear information about the laboratory and field-based methods that can be used to evaluate improvements in individual and team performance, from basic physiological assessment to the use of video and information technologies. Standing at the interface between sport sciences and sport coaching, the book examines a wide range of performance criteria, including: physiology strength, conditioning and fitness decision-making coordination and motor skills sport specific skills team play. Integrating cutting-edge theory, research and technology with best practice in applied sport science, this book is important reading for all students of sport sciences, kinesiology, human movement science, sports performance, or sports coaching. Christopher Carling is Head of Sports Science at Lille Football Club. Thomas Reilly is Director of the Research Institute for Sport and Exercise Sciences at Liverpool John Moores University. He is President of the World Commission of Science and Sports. A. Mark Williams is Professor of Motor Behaviour at the Research Institute for Sport and Exercise Sciences, Liverpool John Moores University.
Full of vital information on vegetarian nutritional needs and healthier, more satisfying diets, the Third Edition can be used as an aid for counseling vegetarian clients and those interested in becoming vegetarians, or serve as a textbook for students who have completed introductory coursework in nutriation. --Book Jacket.
Furnishes table of nonlinear optical properties of organic substances as well as experimental procedures for measuring the nonlinearity of the elements tabulated, including composite materials-offering support for scientists and engineers involved in characterizing, optimizing, and producing materials for manufacturing optical devices.
Since the arrival of European settlers, Native American cultural sovereignty has been under attack. Self-determination is a tribal right of Native people, but colonial oppression banned their traditions and religion, purloined and misused sacred sites, and betrayed treaties when convenient. Over time, the settlers usurped Native American culture and lands, and these destructive behaviors continue today. Within the decimated Native American culture left after forced assimilation, American Indians still struggle to retain their rights. In this historical account of the despotism against Native American culture, the altercations of sovereignty, territory, and pluralistic democracy are analyzed in an effort to provide a path towards justice.
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