This book is for students and researchers who have a specific interest in learning and memory and want to understand how computational models can be integrated into experimental research on the hippocampus and learning. It emphasizes the function of brain structures as they give rise to behavior, rather than the molecular or neuronal details. It also emphasizes the process of modeling, rather than the mathematical details of the models themselves. The book is divided into two parts. The first part provides a tutorial introduction to topics in neuroscience, the psychology of learning and memory, and the theory of neural network models. The second part, the core of the book, reviews computational models of how the hippocampus cooperates with other brain structures -- including the entorhinal cortex, basal forebrain, cerebellum, and primary sensory and motor cortices -- to support learning and memory in both animals and humans. The book assumes no prior knowledge of computational modeling or mathematics. For those who wish to delve more deeply into the formal details of the models, there are optional "mathboxes" and appendices. The book also includes extensive references and suggestions for further readings.
Products Liability Law, Second Edition, by prolific tort scholar Mark Geistfeld, represents the “next generation” of casebooks on products liability. Earlier texts focused on the relative merits of strict liability and negligence, embodied in the apparently competing liability frameworks of the consumer expectations test in the Restatement (Second) of Torts and the risk-utility test in the Restatement (Third) of Torts.The majority of courts, however, have incorporated the risk-utility test into the framework of consumer expectations. By providing balanced coverage of both consumer expectations and the risk-utility test, the casebook keeps pace with ongoing developments in the case law and moves beyond the battles that largely defined products liability in the twentieth century. In addition to teaching students how liability rules protect consumer expectations via comprehensive application of the risk-utility test, this innovative casebook underscores the importance of doctrinal history, the psychology of evaluating product risks, and the role of products liability in the modern regulatory state. Students will learn how courts have applied established doctrines to novel problems ranging from the relevance of scientific evidence in toxic-tort cases to the distribution of defective products on the Amazon online marketplace. To further illustrate this dynamic, the casebook has twenty-nine problems with associated analysis involving the liability issues likely to be raised by the emerging technology of autonomous vehicles. Finally, the casebook reinforces students’ knowledge of fundamental tort principles while developing specialized expertise and a deeper understanding of the torts process. New to the Second Edition: A dozen new main cases updating older case law, providing coverage of new issues not addressed in the First Edition, and/or improving upon the analysis provided by the associated case in the First Edition Retention of the majority of main cases from the first edition, with revisions to the ensuing notes incorporating relevant case law developments A reorganized and updated chapter covering the controversy over the relative merits of the consumer expectations and risk-utility tests Comprehensive discussion of the tort version of the implied warranty—the genesis of the consumer expectations test—and its relation to product malfunctions and the risk-utility test A new chapter addressing the existence of the tort duty and identifying the difference between patent dangers and patent defects Reorganization of the chapter on factual causation, emphasizing the continuity of evidentiary problems running across different types of cases, ranging from the heeding presumption in warning cases, to market-share liability, to proof of both general and specific causation in toxic-tort cases Professors and students will benefit from: Classroom-tested materials taught for over 20 years by an award-winning professor Interesting cases that illustrate both the traditional and contemporary character of products liability litigation; cases are followed by extensive notes Each chapter addressing doctrinal issues concludes with problems on autonomous vehicles. The full set of 29 problems provides students with the necessary background for understanding liability issues posed by this emerging technology. Each problem is followed by the author’s analysis of the associated issues, cross-referenced to the relevant casebook material.
For nearly 50 years, Sleisenger & Fordtran's Gastrointestinal and Liver Disease has been the go-to reference for gastroenterology and hepatology residents, fellows, physicians, and the entire GI caregiving team. Now in a fully revised 11th Edition, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with the newest techniques, technologies, and treatments for every clinical challenge you face in gastroenterology and hepatology. A logical organization, more than 1,100 full-color illustrations, and easy-to-use algorithms ensure that you'll quickly and easily find the information you need. - Features new and expanded discussions of chronic hepatitis B and C, Helicobacter pylori infection, colorectal cancer prevention through screening and surveillance, biologic agents and novel small molecules to treat and prevent recurrences of inflammatory bowel disease (IBD), gastrointestinal immune and autoimmune diseases, and more. - Offers reliable coverage of key topics such as Barrett's esophagus, gut microbiome, enteric microbiota and probiotics, fecal microbiota transplantation, and hepatic, pancreatic, and small bowel transplantation. - Provides more quick-reference algorithms that summarize clinical decision making and practical approaches to patient management. - Employs a consistent, templated, format throughout for quick retrieval of information. - Includes monthly updates online, as well as more than 20 procedural videos. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Enriched and Impoverished Environments: Effects on Brain and Behaviour is the most recent review of the active area of neuronal plasticity. The question of how experience is recorded is fundamental to psychology; speculations and investigations concerning the role of the brain in this process have entered a particularly exciting phase as of the late 1980's. Manipulations of environmental complexity is one of the earliest methods utilized in the study of neural plasticity. This monograph organizes the evidence to date concerning the responsiveness of neural and behavioural systems to external manipulation of the environment. Further consideration is given to the issues of causation of the general effects of environment on brain and behaviour.
The history of music is most often written as a sequence of composers and works. But a richer understanding of the music of the past may be obtained by also considering the afterlives of a composer's works. Genealogies of Music and Memory asks how the stage works of Christoph Willibald Gluck (1714-87) were cultivated in nineteenth-century Paris, and concludes that although the composer was not represented formally on the stage until 1859, his music was known from a wide range of musical and literary environments. Received opinion has Hector Berlioz as the sole guardian of the Gluckian flame from the 1820s onwards, and responsible -- together with the soprano Pauline Viardot -- for the 'revival' of the composer's Orfeo in 1859. The picture is much clarified by looking at the concert performances of Gluck during the first two thirds of the nineteenth century, and the ways in which they were received and the literary discourses they engendered. Coupled to questions of music publication, pedagogy, and the institutional status of the composer, such a study reveals a wide range of individual agents active in the promotion of Gluck's music for the Parisian stage. The 'revival' of Orfeo is contextualised among other attempts at reviving Gluck's works in the 1860s, and the role of Berlioz, Viardot and a host of others re-examined.
Composite decisions are decisions consisting of interconnected parts (subdecisions) and they correspond to a composite (composable, modular, decomposable) system. The material will be of interest to scientists (e.g., mathematicians, computer scientists, economists, social engineers,etc.). The book can be used as a text for courses (for example: systems engineering, system design, life cycle engineering, engineering design, combinatorial synthesis) at the level of undergraduate (a compressed version), graduate/PhD levels and for continuing education.
This book is both a telling of operatic histories 'after' Richard Wagner, and a philosophical reflection upon the writing of those histories. Historical musicology reckons with intellectual and cultural history, and vice versa. The 'after' of the title denotes chronology, but also harmony and antagonism within a Wagnerian tradition. Parsifal, in which Wagner attempted to go beyond his achievement in the Ring, to write 'after' himself, is followed by two apparent antipodes: the strenuously modernist Arnold Schoenberg and the stheticist Richard Strauss. Discussion of Strauss's Capriccio, partly in the light of Schoenberg's Moses und Aron, reveals a more 'political' work than either first acquaintance or the composer's 'intention' might suggest. Then come three composers from subsequent generations: Luigi Dallapiccola, Luigi Nono, and Hans Werner Henze. Geographical context is extended to take in Wagner's Italian successors; the problem of political emancipation in and through music drama takes another turn here, confronting challenges and opportunities in more avowedly 'politically engaged' art. A final section explores the world of staging opera, of so-called Regietheater, as initiated by Wagner himself. Stefan Herheim's celebrated Bayreuth production of Parsifal, and various performances of Lohengrin are discussed, before looking back to Mozart (Don Giovanni) and forward to Alban Berg's Lulu and Nono's Al gran sole carico d'amore. Throughout, the book invites us to consider how we might perceive the sthetic and political integrity of the operatic work 'after Wagner'. After Wagner will be invaluable to anyone interested in twentieth-century music drama and its intersection with politics and cultural history. It will also appeal to those interested in Richard Wagner's cultural impact on succeeding generations of composers. MARK BERRY is Senior Lecturer in Music at Royal Holloway, University of London.
Though Sean O’Hanlon was a United States Navy SEAL and considered himself American above all else, he was irrevocably tied to the land of his birth. Bound to an ancient land, it’s history and it’s people by a seemingly cruel fate, Sean struggles to make sense of the legacy left to him by successive generations of O’Hanlons. He sacrificed everything to become a SEAL like his father before him. However, once the Trident was won he begins to doubt then curse the choices he has made in his life. He longs for the life he could have had with his precious Maggie. Their love transcended their own mortality, yet whether by God’s design or his own ill choices they could never be together. And so Sean is commanded to his fate, embarking on a journey that takes him from the “troubles” in Northern Ireland to the jungles of South East Asia. From sunny California beaches to the wind swept mountains of northern Iran and from the polished corridors of the Pentagon to the cool morning skies above the Iraqi desert. Like pieces of a puzzle, every turn in his life is an integral part of a prophetic equation. Trained as a Navy SEAL he is an expert in the special warefare arena. And in the flooded tunels of Cambodia, he learns first hand about the horrors of biological weapons. Ultimately, the final piece of the puzzle leads Sean back to where it all began- his native Derry. A terrorist holds the United Kingdom hostage with the threat of releasing a deadly virus. And only Sean O'Hanlon knows where to find him and how to stop him. Through it all, he strives to make his own destiny, only to succumb time and time again to an unyielding fate; the fate of Irish sons.
This book is for students and researchers who have a specific interest in learning and memory and want to understand how computational models can be integrated into experimental research on the hippocampus and learning. It emphasizes the function of brain structures as they give rise to behavior, rather than the molecular or neuronal details. It also emphasizes the process of modeling, rather than the mathematical details of the models themselves. The book is divided into two parts. The first part provides a tutorial introduction to topics in neuroscience, the psychology of learning and memory, and the theory of neural network models. The second part, the core of the book, reviews computational models of how the hippocampus cooperates with other brain structures -- including the entorhinal cortex, basal forebrain, cerebellum, and primary sensory and motor cortices -- to support learning and memory in both animals and humans. The book assumes no prior knowledge of computational modeling or mathematics. For those who wish to delve more deeply into the formal details of the models, there are optional "mathboxes" and appendices. The book also includes extensive references and suggestions for further readings.
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