Bribes, Bullets, and Intimidation is the first book to examine drug trafficking through Central America and the efforts of foreign and domestic law enforcement officials to counter it. Drawing on interviews, legal cases, and an array of Central American sources, Julie Bunck and Michael Fowler track the changing routes, methods, and networks involved, while comparing the evolution and consequences of the drug trade through Belize, Costa Rica, Guatemala, Honduras, and Panama over a span of more than three decades. Bunck and Fowler argue that while certain similar factors have been present in each of the Central American states, the distinctions among these countries have been equally important in determining the speed with which extensive drug trafficking has taken hold, the manner in which it has evolved, the amounts of different drugs that have been transshipped, and the effectiveness of antidrug efforts.
During the past 20 years, transgenesis has become a popular technique and a crucial tool for molecular geneticists and biologists. Transgene expression is now better-controlled and even specifically inducible by exogenous factors. While these techniques have quite significantly transformed the experimental approaches taken by biologists, the applications are more limited than expected and concerns have arisen regarding biosafety as well as physiological, social, and philosophical issues. Transgenic Animals: Generation and Use contains articles on the techniques used to generate transgenic animals and a section on the preparation of vectors for the optimally controlled expression of transgenes. It also examines the use of transgenic animals in the study of gene function and human diseases, the preparation of recombinant proteins and organs for pharmaceutical and medical use, and the improvement of genetic characteristics of farm animals. Finally, it discusses more recent problems generated by transgenic animals including conservation of transgenic lines, specific database patenting, biosafety, and bioethics. Drawn from both academia and industry, the contributors to this monograph present in one concise volume all the relevant information on the different aspects of transgenesis. This book can be used as both a reference book and a textbook for specialized university courses and will be of interest to everyone involved in basic research in animal biology, molecular genetics, animal biotechnology, pharmaceutical science, and medicine.
How to manage the cybersecurity of industrial systems is a crucial question. To implement relevant solutions, the industrial manager must have a clear understanding of IT systems, of communication networks and of control-command systems. They must also have some knowledge of the methods used by attackers, of the standards and regulations involved and of the available security solutions. Cybersecurity of Industrial Systems presents these different subjects in order to give an in-depth overview and to help the reader manage the cybersecurity of their installation. The book addresses these issues for both classic SCADA architecture systems and Industrial Internet of Things (IIoT) systems.
Monitoring vegetation dynamics and land cover change in Kenya are essential for the sustainable management of natural resources and biodiversity conservation. However, accurate status of seasonal variation in vegetation and long-term land cover change data valid at the regional and country level generally do not exist or are hard to obtain. Here, we describe the various ecological regions of Kenya and the associated rainfall and land cover patterns of each ecological zone. This includes the use of low-resolution satellite data time series to characterise for each ecoregion and land cover type the interannual variability of the vegetation cycle, including the start-, mid- and end of the growing season. Seasonal variation in vegetation phenology is mapped to highlight the areas of greatest interannual variation and compared to rainfall patterns over the focal study period. Statistical estimates of land cover change are produced for six broad classes for the years 1990, 2000 and 2010, based on detailed land cover change assessed by a systematic sampling of high-resolution satellite imagery. Rates of change for Kenya are presented and discussed in light of the low-resolution time series analysis. Results highlight information on land cover change processes such as vegetation dynamics and deforestation. These are discussed within the context of the drivers of changes to the natural ecosystem—their potential impact on land availability for human activities such as agriculture and logging for timber and fire wood production on the one side and habitat and biodiversity conservation on the other side. Finally, biodiversity and habitat value, ecosystems and threats are analysed for Kenya’s conservation and protected areas so as to identify the status of and pressures on the country’s protected areas. Six indicators of species irreplaceability, habitat irreplaceability and the level of perceived threat to a protected area’s habitat and species from agriculture and human population are analysed. In addition, high-resolution satellite images taken over conservation areas are used for assessing land cover changes inside protected areas and in the surrounding 20km buffer zone. The results show the importance and effectiveness of protected areas in reducing the loss of natural vegetation and hence protecting the habitats and biodiversity.
The Norman conquerors of Anglo-Saxon England have traditionally been seen both as rapacious colonizers and as the harbingers of a more civilized culture, replacing a tribal Germanic society and its customs with more refined Continental practices. Many of the scholarly arguments about the Normans and their influence overlook the impact of the past on the Normans themselves. The Continuity of the Conquest corrects these oversights. Wendy Marie Hoofnagle explores the Carolingian aspects of Norman influence in England after the Norman Conquest, arguing that the Normans’ literature of kingship envisioned government as a form of imperial rule modeled in many ways on the glories of Charlemagne and his reign. She argues that the aggregate of historical and literary ideals that developed about Charlemagne after his death influenced certain aspects of the Normans’ approach to ruling, including a program of conversion through “allurement,” political domination through symbolic architecture and propaganda, and the creation of a sense of the royal forest as an extension of the royal court. An engaging new approach to understanding the nature of Norman identity and the culture of writing and problems of succession in Anglo-Norman England, this volume will enlighten and enrich scholarship on medieval, early modern, and English history.
A scientific look at the biological bases of human nutrition. Covering advanced nutrition with a comprehensive, easy-to-understand approach, Biochemical, Physiological, and Molecular Aspects of Human Nutrition, 4th Edition, focuses on nutrition at the molecular, cellular, tissue, and whole-body levels. Written by Martha Stipanuk, Marie Caudill, and a team of nutrition experts, the text addresses nutrients by classification, and describes macronutrient function from digestion to metabolism. This edition includes the most current recommendations from the Dietary Guidelines for Americans, plus coverage of the historical evolution of nutrition and information on a wide range of vitamins, minerals, and other food components. More than 20 expert contributors provide the latest information on all areas of the nutrition sciences. Thinking Critically sections within boxes and at the end of chapters help in applying scientific knowledge to "real-life" situations. Common Abbreviations for the entire book are listed alphabetically on the inside back cover for easy reference. Nutrition Insight boxes discuss hot topics and take a closer look at basic science and everyday nutrition. Clinical Correlation boxes show the connection between nutrition-related problems and their effects on normal metabolism. Food Sources boxes summarize and simplify data from the USDA National Nutrient Database on the amount and types of foods needed to reach the recommended daily allowances for vitamins and minerals. DRIs Across the Life Cycle boxes highlight the latest data from the Institute of Medicine on dietary reference intakes for vitamins and minerals, including coverage of infants, children, adult males and females, and pregnant and lactating women. Historical Tidbit boxes provide a historical context to key nutritional findings. NEW! Thoroughly updated art program helps to clarify complex concepts. NEW! Select bolded summary headings enable students to efficiently review information and recognize major messages NEW! Content updated throughout incorporates the latest research and findings, including extensively revised coverage of lipids, lipoproteins, cholesterol, fatty acids, and triacylglycerol metabolism. NEW! Improved writing style makes the material more concise, direct, and accessible. NEW! Additional boxes, tables, and critical thinking questions break up the narrative and reinforce key concepts.
This study provides a new insight in the development and background of the church-political and ecclesiological ideas of the famous chancellor of the Paris University, Jean Gerson (1363-1429).
Digital commerce – the use of computer networks to facilitate transactions involving the production, distribution, sale, and delivery of goods and services – has grown from merely streamlining relations between consumer and business to a much more robust phenomenon embracing efficient business processes within a firm and between firms. Inevitably, the related taxation issues have grown as well. This latest edition of the preeminent text on the taxation of digital transactions revises, updates and expands the book’s coverage. It includes a detailed and up-to-date analysis of income tax and VAT developments regarding digital commerce under the OECD and G20 Base Erosion and Profit Shifting (BEPS) reforms. It explores the implications of digital commerce for US state sales and use tax regimes resulting from the 2018 US Supreme Court decision in Wayfair. It discusses cross-border tax in the United States while continuing to focus on tax developments throughout the world. Analysing the practical tax consequences of digital commerce from a multijurisdictional perspective, and using examples to illustrate the application of different taxes to digital commerce transactions, the book offers in-depth treatment of such topics as the following: how tax rules governing cross-border digital commerce are increasingly applied to all cross-border activities; how tax rules and institutional processes have evolved to confront challenges posed by digital commerce; how an emerging ‘tax war’ is developing whereby different countries are unilaterally imposing new tax rules on cross-border digital commerce; how technology enhances tax and cross-border tax information exchanges; how technology reduces both compliance and enforcement costs; cross-border consumption tax issues raised by cloud computing; and different approaches to the legal design of VAT place of taxation rules. The authors offer insightful views on the likely development of new approaches to taxing cross-border digital commerce. This edition, while building on the analysis of the relationship between traditional tax laws and the Internet in the first edition and its predecessors, contains a more explicit and systematic consideration of digital commerce issues and the ongoing policy responses to them. Tax professionals and academics everywhere will welcome the important contribution it makes towards the design of cross-border tax rules that are both conceptually sound and practical in application. ‘A tour de force … much larger and richer than its predecessors … a massive contribution to the growing literature on the taxation of e-commerce.’ – Rita de la Feria, British Tax Review ‘Provides important understandings for ongoing policy discussions … I would warmly recommend.’ – P. Rendahl, World Journal of VAT/GST Law
This book presents a modern perspective on the modelling, analysis, and synthesis ideas behind convex-optimisation-based control of nonlinear systems: it embeds them in models with convex structures. Analysis and Synthesis of Nonlinear Control Systems begins with an introduction to the topic and a discussion of the problems to be solved. It then explores modelling via convex structures, including quasi-linear parameter-varying, Takagi–Sugeno models, and linear fractional transformation structures. The authors cover stability analysis, addressing Lyapunov functions and the stability of polynomial models, as well as the performance and robustness of the models. With detailed examples, simulations, and programming code, this book will be useful to instructors, researchers, and graduate students interested in nonlinear control systems.
Breast Pathology, a title in the Foundations in Diagnostic Pathology series, provides all of the most essential information on the pathological entities encountered in practice in an easy-to-use format. Drs. Frances P. O'Malley, Sarah E. Pinder, and Anna Marie Mulligan provide unparalleled expert guidance for the study and diagnosis of a broad spectrum of breast lesions as well as the broad range of appearances of normal breast tissue. The consistent, practical format with a wealth of illustrations, at-a-glance boxes, and tables, make this title ideal for quick reference for both novices and experienced breast pathologists. Reference key information quickly and easily with a consistent, user-friendly format and at-a-glance boxes and tables throughout the text. Examine all aspects of a pathologic entity, including clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnosis, and prognostic and therapeutic considerations. Catch all the nuances of how pathological lesions present through over 400 full-color illustrations. Practice with confidence and overcome your toughest challenges with advice from the top minds in breast pathology. Apply the latest molecular diagnostic techniques to recognize newly identified classifications in breast disease. Get more of the information you need from new and expanded chapters covering a broad range of diseases and topics including fine needle aspiration cytology and the physical handling of core biopsy specimens; handling and evaluation of sentinel lymph nodes; diseases of the male breast; and state-of-the-art coverage of molecular advances in malignant breast disease. Prepare for the future of breast pathology with a new chapter dedicated to gene profiling and stem cell diagnostic techniques.
From trendy cities to classic fishing villages, soak up the romance of this charming country with Moon Portugal. Inside you'll find: Strategic, flexible itineraries including a two-week tour of the best of Portugal, a five-day trip to charming villages, and more Must-see highlights and unique experiences: Relax on a beach sipping vinho verde and snacking on freshly grilled sardines (a Portuguese classic!). Shop for hand-painted tiles or authentic leather goods, visit the famous Port wine cellars, or browse contemporary galleries and museums along Lisbon's cosmopolitan avenues. Savor a romantic meal on cobblestone esplanades and catch a traditional fado show in an intimate bar. Explore the Roman ruins in Évora, trek majestic mountain ranges, cruise the Sado River, or soak in a volcanic hot spring Trusted local advice from long-time Portugal resident Carrie-Marie Bratley Full-color photos and detailed maps throughout Background information on Portugal's landscape, history, and cultural customs In-depth coverage of Lisbon, the Algarve, the Alentejo, Porto and Northern Portugal, Coimbra and Central Portugal, and the Azores and Madeira Handy tools such as visa information, a Portuguese phrasebook, and tips for traveling with children or as a senior With Moon Portugal's practical tips and local insight, you can plan your trip your way. Exploring more of Portugal? Check out Moon Azores. About Moon Travel Guides: Moon was founded in 1973 to empower independent, active, and conscious travel. We prioritize local businesses, outdoor recreation, and traveling strategically and sustainably. Moon Travel Guides are written by local, expert authors with great stories to tell—and they can't wait to share their favorite places with you. For more inspiration, follow @moonguides on social media.
This new and revised version of the successful manual, Home Care IV Therapy, provides a practical, comprehensive reference on safe and effective home IV therapy. it offers all the information needed to operate and administer a quality home IV therapy program with step-by-step instructions for performing procedures, criteria for certification and recertification, recommended agency policies and protocols, staff education material, sample worksheets, and illustrated patient education manuals. The manual also includes discussions of medications approved for IV administration and a chemotherapy drug manual, all in a convenient looseleaf format. it also features directions For The care and maintenance of the many new types of catheters that have come on the market in recent years. The manual is a complete and comprehensive infusion manual.
Organisations continually use integrated marketing communications to achieve a competitive advantage and meet their marketing objectives. This 5th edition of Integrated Marketing Communications emphasises digital and interactive marketing, the most dynamic and crucial components to a successful IMC campaign today. Incorporating the most up-to-date theories and practice, this text clearly explains and demonstrates how to best select and co-ordinate all of a brand's marketing communications elements to effectively engage the target market. Chapters adopt an integrative approach to examine marketing communications from both a consumer's and marketer's perspective. With a new chapter on digital and social marketing addressing the development of interactive media in IMC and new IMC profiles featuring Australian marketer's, along with a wide range of local and global examples including: Spotify, Pandora, Snapchat, Palace Cinemas, Woolworths, KFC, Old Spice, Telstra, Colgate and QANTAS, this text has never been so relevant for students studying IMC today. Unique to the text, is a series of new student and instructor IMC videos showing students how key objectives in IMC theory are applied by real businesses.
Discover the habits that distinguish true business professionals—and how to make a great impression on customers, clients, and colleagues. Many people invest in their careers, yet have no clue how to set themselves apart from their competition. This guide, from the author of What Self-Made Millionaires Do That Most People Don’t, reveals the unwritten and unspoken rules of success. It gives new hires and seasoned executives alike nearly effortless strategies—for avoiding mistakes that hold you back and climbing that slippery ladder of success. You’ll learn appropriate ways to: •Introduce two people whose names you've forgotten •Ask for some of your boss’s time •Manage coworkers who drop into your office on a moment's notice •Handle being put on the spot in a meeting •Play the corporate hierarchy game with your boss and other higher-ups •Deal with international hosts, colleagues and customers, and much more
From trendy cities to classic fishing villages, soak up the romance of this charming country with Moon Portugal. Inside you'll find: Strategic, flexible itineraries including a ten-day tour of the best of Portugal and two days in Lisbon, designed for foodies, art lovers, history buffs, and more Must-see highlights and unique experiences: Relax on a beach sipping vinho verde and snacking on freshly grilled sardines (a Portuguese classic!). Shop for hand-painted tiles or authentic leather goods, visit the famous Port wine cellars, or browse contemporary galleries and museums along Lisbon's cosmopolitan avenues. Savor a romantic meal on cobblestone esplanades and catch a traditional fado show in an intimate bar. Explore the Roman ruins in Évora, trek majestic mountain ranges, cruise the Sado River, or soak in a volcanic hot spring Trusted advice from long-time Portugal resident Carrie-Marie Bratley Full-color photos and detailed maps throughout Background information on Portugal's landscape, history, and cultural customs In-depth coverage of Lisbon, the Algarve, the Alentejo, Porto and Northern Portugal, Coimbra and Central Portugal, and the Azores and Madeira Handy tools such as visa information, a Portuguese phrasebook, and tips for traveling with children or as a senior With Moon Portugal's practical tips and local insight, you can plan your trip your way. Seeing more of the Iberian Peninsula? Check out Moon Barcelona & Madrid or Moon Barcelona Walks.
Principles of Virology is the leading virology textbook because it does more than collect and present facts about individual viruses. Instead, it facilitates an understanding of basic virology by examining the shared processes and capabilities of viruses. Using a set of representative viruses to present the complexity and diversity of a myriad of viruses, this rational approach enables students to understand how reproduction is accomplished by known viruses and provides the tools for future encounters with new or understudied viruses. This fully updated edition represents the rapidly changing field of virology. A major new feature is the inclusion of 26 video interviews with leading scientists who have made significant contributions to the field of virology. Applicable courses: undergraduate courses in virology and microbiology as well as graduate courses in virology and infectious diseases.
Illegal immigration has been near the top of the political agendas of the member states of the Council of Europe for almost two decades. They are worried about the scale of the problem and frightened that it might exacerbate existing social tensions. This report, which was discussed at the 7th conference of European Ministers responsible for Migration Affairs in Helsinki in September 2002, surveys the problems and offers some recommendations on future policy. After defining illegal immigration, it discusses the organised traffic in human beings and the measures to control and deter settlement. It then examines the particular problems of the enlargement of the EU and Community policy before looking at the underlying demographic and economic trends and their effect on the labour market. The recommendations focus on a desire for a transparent system, which harmonises asylum and immigration policy and allows a positive regulation of labour migration.
Drawn from five large volumes published between 1825 and 1882, this student's edition showcases the architectural splendor of Renaissance Rome for a new generation. Paul Letarouilly's original work constitutes the standard reference, presenting the mostcomplete collection of plans, elevations, and details of great buildings and monuments designed by Michelangelo, Peruzzi, Vignola, Bernini, and many others. "--
Principles of Virology, the leading virology textbook in use, is an extremely valuable and highly informative presentation of virology at the interface of modern cell biology and immunology. This text utilizes a uniquely rational approach by highlighting common principles and processes across all viruses. Using a set of representative viruses to illustrate the breadth of viral complexity, students are able to under-stand viral reproduction and pathogenesis and are equipped with the necessary tools for future encounters with new or understudied viruses. This fifth edition was updated to keep pace with the ever-changing field of virology. In addition to the beloved full-color illustrations, video interviews with leading scientists, movies, and links to exciting blogposts on relevant topics, this edition includes study questions and active learning puzzles in each chapter, as well as short descriptions regarding the key messages of references of special interest. Volume I: Molecular Biology focuses on the molecular processes of viral reproduction, from entry through release. Volume II: Pathogenesis and Control addresses the interplay between viruses and their host organisms, on both the micro- and macroscale, including chapters on public health, the immune response, vaccines and other antiviral strategies, viral evolution, and a brand new chapter on the therapeutic uses of viruses. These two volumes can be used for separate courses or together in a single course. Each includes a unique appendix, glossary, and links to internet resources. Principles of Virology, Fifth Edition, is ideal for teaching the strategies by which all viruses reproduce, spread within a host, and are maintained within populations. This edition carefully reflects the results of extensive vetting and feedback received from course instructors and students, making this renowned textbook even more appropriate for undergraduate and graduate courses in virology, microbiology, and infectious diseases.
Distribution systems drive energy and societal transition. System planning enables investments to be made in the right place, at the right time and with the right technology. Distribution System Planning is centered on the evolution of planning methods that will best support this transition, and describes the historical context and concepts that enable planning, its challenges and key influencing factors to be grasped. It also analyzes the impact of the development of renewable and decentralized energy resources, government recommendations and distributor initiatives to promote their integration. Through the use of case studies, this book provides examples of how planning methodologies have evolved, as well as an overview of new and emerging solutions.
This updated and revised third edition of the leading reference volume on distance metrics includes new items from very active research areas in the use of distances and metrics such as geometry, graph theory, probability theory and analysis. Among the new topics included are, for example, polyhedral metric space, nearness matrix problems, distances between belief assignments, distance-related animal settings, diamond-cutting distances, natural units of length, Heidegger’s de-severance distance, and brain distances. The publication of this volume coincides with intensifying research efforts into metric spaces and especially distance design for applications. Accurate metrics have become a crucial goal in computational biology, image analysis, speech recognition and information retrieval. Leaving aside the practical questions that arise during the selection of a ‘good’ distance function, this work focuses on providing the research community with an invaluable comprehensive listing of the main available distances. As well as providing standalone introductions and definitions, the encyclopedia facilitates swift cross-referencing with easily navigable bold-faced textual links to core entries. In addition to distances themselves, the authors have collated numerous fascinating curiosities in their Who’s Who of metrics, including distance-related notions and paradigms that enable applied mathematicians in other sectors to deploy research tools that non-specialists justly view as arcane. In expanding access to these techniques, and in many cases enriching the context of distances themselves, this peerless volume is certain to stimulate fresh research.
Principles of Virology, the leading virology textbook in use, is an extremely valuable and highly informative presentation of virology at the interface of modern cell biology and immunology. This text utilizes a uniquely rational approach by highlighting common principles and processes across all viruses. Using a set of representative viruses to illustrate the breadth of viral complexity, students are able to understand viral reproduction and pathogenesis and are equipped with the necessary tools for future encounters with new or understudied viruses. This fifth edition was updated to keep pace with the ever-changing field of virology. In addition to the beloved full-color illustrations, video interviews with leading scientists, movies, and links to exciting blogposts on relevant topics, this edition includes study questions and active learning puzzles in each chapter, as well as short descriptions regarding the key messages of references of special interest. Volume I: Molecular Biology focuses on the molecular processes of viral reproduction, from entry through release. Volume II: Pathogenesis and Control addresses the interplay between viruses and their host organisms, on both the micro- and macroscale, including chapters on public health, the immune response, vaccines and other antiviral strategies, viral evolution, and a brand new chapter on the therapeutic uses of viruses. These two volumes can be used for separate courses or together in a single course. Each includes a unique appendix, glossary, and links to internet resources. Principles of Virology, Fifth Edition, is ideal for teaching the strategies by which all viruses reproduce, spread within a host, and are maintained within populations. This edition carefully reflects the results of extensive vetting and feedback received from course instructors and students, making this renowned textbook even more appropriate for undergraduate and graduate courses in virology, microbiology, and infectious diseases.
The fascinating area of Nutrigenomics describes this daily communication between our diet and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannahs of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms. The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book represents an updated but simplified version of our textbook “Nutrigenomics” (ISBN 978-3-319-30413-7). Besides its value as a textbook, “Nutrigenomics: how science works” will be a useful reference for individuals working in biomedicine
This work provides a new narrative for Orsanmichele in the era before the Renaissance. It examines Orsanmichele from the mid-thirteenth century, as the piazza transformed into the city’s grain market. It considers the market’s tandem confraternity, with its stunning Madonnas over three successive loggias. It examines the grain market and confraternity from a social, economic, political, and artistic perspective. It provides extensive data on the Florentine grain trade, sales at the market, and the nexus between traders, political leaders, and the confraternity. The work suggests that developments at Orsanmichele during the medieval period formed the basis for the Renaissance structure.
Gibbs, one of the original activists from the contaminated neighborhoods at Love Canal, explains what dioxin is and describes how it affects human health, summarizing the September 1994 EPA draft report on dioxin and important reports published since the EPA report. She reviews the politics surrounding the history of dioxin, and offers step-by-step instructions for grass-roots organizing, creating a coalition, identifying sources of contamination in the community, and shutting down an incinerator. Contains appendices on the chemistry of dioxin, conversion charts, sample ordinances, agreements and resolutions, and a declaration of principles of environmental justice. Annotation copyright by Book News, Inc., Portland, OR
This book deals with the prediction of possible future scenarios concerning the COVID-19 pandemic. Based on the well-known SIR model by Kermack and McKendrick a compartment model is established. This model comprises its own assumptions, transition rates and transmission dynamics, as well as a corresponding system of ordinary differential equations. Making use of numerical methods and a nonstandard-finite-difference scheme, two submodels are implemented in Matlab in order to make parameter estimations and compare different scenarios with each other.
Sometimes we have HUGE expectations for the ideal relationship, but dating isn’t about being perfect or catching the perfect partner; it’s all about creating compassionate self-awareness and stronger self-esteem. A must-read for daters, this no-nonsense guide from clinical psychologist Carla Marie Manly, PhD, takes the guesswork out of dating with real-life examples, the latest research, and 33 vital mindset shifts designed to foster: empowered communication, strong, healthy boundaries, realistic, mindful expectations, increased red flag awareness, healthy dating dynamics, and more! Self-discovery is key to healthy relationships. Your life will change when you discover how to date strong, date fearlessly, and date smart.
In this twist on Phantom of the Opera, 16-year-old Enna Evans runs away from boarding school to Paris, France, where she joins a theater company. After she learns of a mysterious person named Skyla connected to the opera house, she becomes entangled in a curse.
Providing a concise, yet comprehensive, reference on all aspectsof industrial exposures and toxicants; this book aidstoxicologists, industrial hygienists, and occupational physiciansto investigate workplace health problems. • Updates and expands coverage with new chapterscovering regulatory toxicology, toxicity testing, physical hazards,high production volume (HPV) chemicals, and workplace druguse • Includes information on occupational and environmentalsources of exposure, mammalian toxicology, industrial hygiene,medical management and ecotoxicology • Retains a succinct chapter format that has become thehallmark for the previous editions • Distils a vast amount of information into one resourcefor both academics and professionals
The fascinating area of Nutrigenomics describes this daily communication between diet, food and nutrients, their metabolites and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannas of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life, and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms. The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. We are not aiming to compete with more comprehensive textbooks on molecular nutrition, evolutionary biology, genomics, gene regulation or metabolic diseases, but rather will focus on the essentials and will combine, in a compact form, elements from different disciplines. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule “a picture tells more than thousand words”. The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book is subdivided into three sections and twelve chapters. Following the "Introduction" there are sections on the "Molecular genetic basis" and the "Links to disease", which take a view on nutrigenomics from the perspective of molecular mechanisms or from the causes of metabolic diseases, respectively. Besides its value as a textbook, Nutrigenomics will be a usefull reference for individuals working in biomedicine.
About one-third of countries covered by the IMF's African Department are members of the CFA franc zone. With most other countries moving away from fixed exchange rates, the issue of an adequate policy framework to ensure the sustainability of the CFA franc zone is clearly of interest to policymakers and academics. However, little academic research exists in the public domain. This book aims to fill this void by bringing together work undertaken in the context of intensified regional surveillance and highlighting the current challenges and the main policy requirements if the arrangements are to be carried forward. The book is based on empirical research by a broad group of IMF economists, with contributions from several outside experts.
Juan de Segovia (d. 1458), theologian, translator of the Qur'ān, and lifelong advocate for the forging of peaceful relations between Christians and Muslims, was one of Europe's leading intellectuals. Today, however, few scholars are familiar with this important fifteenth-century figure. In this well-documented study, Anne Marie Wolf presents a clear, chronological narrative that follows the thought and career of Segovia, who taught at the University of Salamanca, represented the university at the Council of Basel (1431–1449), and spent his final years arguing vigorously that Europe should eschew war with the ascendant Ottoman Turks and instead strive to convert them peacefully to Christianity. What could make a prominent thinker, especially one who moved in circles of power, depart so markedly from the dominant views of his day and advance arguments that he knew would subject him to criticism and even ridicule? Although some historians have suggested that the multifaith heritage of his native Spain accounts for his unconventional belief that peaceful dialogue with Muslims was possible, Wolf argues that other aspects of his life and thought were equally important. For example, his experiences at the Council of Basel, where his defense of conciliarism in the face of opposition contributed to his ability to defend an unpopular position and where his insistence on conversion through peaceful means was bolstered by discussions about the proper way to deal with the Hussites, refined his arguments that peaceful conversion was prefereable to war. Ultimately Wolf demonstrates that Segovia's thought on Islam and the proper Christian stance toward the Muslim world was consistent with his approach to other endeavors and with cultural and intellectual movements at play throughout his career.
Chimpanzees, including bonobos and common chimpanzees, are our closest living relatives. However, surprisingly, the information about the soft tissues of bonobos is very scarce, making it difficult to discuss and understand human evolution. This book, which is the first photographic and descriptive musculoskeletal atlas of bonobos (Pan paniscus), adopts the same format as the photographic atlases of other apes previously published by the same authors. These books are part of a series of monographs that will set out the comparative and phylogenetic context of the gross anatomy and evolutionary history of the soft tissue morphology of modern humans and their closest relatives. The present atlas, which includes detailed high quality photographs of the musculoskeletal structures from most anatomical regions of the body as well as textual information about the attachments, innervation, function and weight of the respective muscles, is based on dissections of seven bonobos, including adults, adolescents, infants and fetuses, and males and females, and on an extensive review of the literature for comparisons with common chimpanzees. It therefore provides an updated review of the anatomical variations within chimpanzees as well as an extensive list of synonyms used in the literature to designate the structures covered here. Moreover, contrary to the previous photographic atlases of apes, it also provides details on neurovascular structures such as the brachial and lumbrosacral plexuses. The book will therefore be of interest to students, teachers and researchers focusing on primatology, comparative anatomy, functional morphology, zoology, and physical anthropology and to medical students, doctors and researchers who are curious about the origin, evolution, homology and variations of the musculoskeletal and neurovascular structures of modern humans.
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