Chimpanzees, including bonobos and common chimpanzees, are our closest living relatives. However, surprisingly, the information about the soft tissues of bonobos is very scarce, making it difficult to discuss and understand human evolution. This book, which is the first photographic and descriptive musculoskeletal atlas of bonobos (Pan paniscus), adopts the same format as the photographic atlases of other apes previously published by the same authors. These books are part of a series of monographs that will set out the comparative and phylogenetic context of the gross anatomy and evolutionary history of the soft tissue morphology of modern humans and their closest relatives. The present atlas, which includes detailed high quality photographs of the musculoskeletal structures from most anatomical regions of the body as well as textual information about the attachments, innervation, function and weight of the respective muscles, is based on dissections of seven bonobos, including adults, adolescents, infants and fetuses, and males and females, and on an extensive review of the literature for comparisons with common chimpanzees. It therefore provides an updated review of the anatomical variations within chimpanzees as well as an extensive list of synonyms used in the literature to designate the structures covered here. Moreover, contrary to the previous photographic atlases of apes, it also provides details on neurovascular structures such as the brachial and lumbrosacral plexuses. The book will therefore be of interest to students, teachers and researchers focusing on primatology, comparative anatomy, functional morphology, zoology, and physical anthropology and to medical students, doctors and researchers who are curious about the origin, evolution, homology and variations of the musculoskeletal and neurovascular structures of modern humans.
This book, first published in 1991, is a revised and updated version of Professor Marie Lavigne's best seller Economie Internationale des Pays Socialistes.
This book constitutes the thoroughly refereed post-proceedings of the 5th International Workshop on Engineering Societies in the Agents World, ESAW 2004, held in Toulouse, France, in October 2004. The 23 revised full papers presented together with an invited paper went through two rounds of reviewing and improvement and were carefully selected from 48 initial submissions. The papers are organized in topical sections on roles, organizations, and institutions for agents; social issues in multi-agent systems; cooperation and collective behavior in agent societies; methodologies and platforms for agent-oriented engineering; agent-oriented simulation; and models for multi-agent systems.
Extensively revised and expanded, Practical Thoracic Pathology: Diseases of the Lung, Heart, and Thymus (formerly Practical Cardiovascular Pathology) is a superbly illustrated, one-volume reference to pathology of the thorax. More than 1,000 full-color illustrations, tables, and “practical points” boxes help you arrive at a diagnosis accurately and efficiently. Ideal for both pathology residents and practicing surgical pathologists, this in-depth resource focuses on illustrated practical diagnosis, including differential diagnosis.
Fresh perspectives on political theater and its essential contribution to contemporary culture. Focused studies of individual plays complement broad-based discussions of the place of theater in a radically democratic society. This consistently challenging collection describes the art of change confronting the actual processes of change. 17 photos.
One of the key features of biological systems is complexity, where the behavior of high level structures is more than the sum of the direct interactions between single components. Synthetic Biologists aim to use rational design to build new systems that do not already exist in nature and that exhibit useful biological functions with different levels of complexity. One such case is metabolic engineering, where, with the advent of genetic and protein engineering, by supplying cells with chemically synthesized non-natural amino acids and sugars as new building blocks, it is now becoming feasible to introduce novel physical and chemical functions and properties into biological entities. The rules of how complex behaviors arise, however, are not yet well understood. For instance, instead of considering cells as inert chassis in which synthetic devices could be easily operated to impart new functions, the presence of these systems may impact cell physiology with reported effects on transcription, translation, metabolic fitness and optimal resource allocation. The result of these changes in the chassis may be failure of the synthetic device, unexpected or reduced device behavior, or perhaps a more permissive environment in which the synthetic device is allowed to function. While new efforts have already been made to increase standardization and characterization of biological components in order to have well known parts as building blocks for the construction of more complex devices, also new strategies are emerging to better understand the biological dynamics underlying the phenomena we observe. For example, it has been shown that the features of single biological components [i.e. promoter strength, ribosome binding affinity, etc] change depending on the context where the sequences are allocated. Thus, new technical approaches have been adopted to preserve single components activity, as genomic insulation or the utilization of prediction algorithms able to take biological context into account. There have been noteworthy advances for synthetic biology in clinical technologies, biofuel production, and pharmaceuticals production; also, metabolic engineering combined with microbial selection/adaptation and fermentation processes allowed to make remarkable progress towards bio-products formation such as bioethanol, succinate, malate and, more interestingly, heterologous products or even non-natural metabolites. However, despite the many progresses, it is still clear that ad hoc trial and error predominates over purely bottom-up, rational design approaches in the synthetic biology community. In this scenario, modelling approaches are often used as a descriptive tool rather than for the prediction of complex behaviors. The initial confidence on a pure reductionist approach to the biological world has left space to a new and deeper investigation of the complexity of biological processes to gain new insights and broaden the categories of synthetic biology. In this Research Topic we host contributions that explore and address two areas of Synthetic Biology at the intersection between rational design and natural complexity: (1) the impact of synthetic devices on the host cell, or "chassis" and (2) the impact of context on the synthetic devices. Particular attention will be given to the application of these principles to the rewiring of cell metabolism in a bottom-up fashion to produce non-natural metabolites or chemicals that should eventually serve as a substitute for petrol-derived chemicals, and, on a long-term view, to provide economical, ecological and ethical solutions to today’s energetic and societal challenges.
Provides detailed listings of more than 4,100 programs sponsored by U.S. and foreign universities, language schools, and a wide variety of other organizations.
To Catch a Virus To Catch a Virus Trace the evolution of diagnostic virology from yellow fever to COVID-19 Join expert storytellers John Booss, Marilyn J. August, and Marie Louise Landry in a journey through the history of viral epidemics and the detective work of those determined to identify the culprits and treat the infected. From the identification of the first virus in the late 1800s to the molecular techniques that enabled the rapid recognition of and vaccine development for the SARS-CoV-2 virus, viral diagnostic methods have progressed over the past century to become a formidable tool in human health care. This collection of gripping historical narratives covers a range of fascinating outbreaks and public health challenges, from yellow fever and smallpox to AIDS and COVID-19. This new edition chronicles the ongoing story of the COVID-19 pandemic, highlighting the people, the pathogen, and the progress in the diagnostic laboratory and clinical settings that has touched every aspect of global health. The many photographs and rich biographical sketches of key figures, diagrams of diagnostic procedures, micrographs of virus-infected cells, timelines, and a new glossary of key terms make To Catch a Virus compelling reading. This book serves as an excellent resource for courses in virology, immunology, microbiology, and public health. As the world struggles with the ongoing pandemic of SARS-CoV-2/COVID-19, To Catch a Virus is an insightful and superbly told story that chronicles the incredible metamorphosis of diagnostic virology and the technological advances that now make it possible to quickly and accurately detect and monitor the many disease-causing viruses that plague humankind. A stimulating, informative, and absorbing read that is highly recommended. —Richard L. Hodinka, PhD, Professor Emeritus, Perelman School of Medicine at the University of Pennsylvania; former Director, Clinical Virology Laboratory, Children’s Hospital of Philadelphia To Catch a Virus provides a beautifully written and compelling story of scientific discovery. It carefully traces the understanding of viral diseases from the turn of the twentieth century to the present. For general readers the authors provide timely and expert guidance to the extraordinary advances in diagnosis, surveillance, and therapeutics that constitute the silver lining in the otherwise somber years of COVID-19. For anyone wishing to understand the challenges confronting virologists and their accomplishments to date, this work is the place to start. —Frank M. Snowden, PhD, Andrew Downey Orrick Professor Emeritus of History, Yale University; former Chair, Program in History of Science and History of Medicine, Yale University
The most complete reference work on mosquitoes ever produced, Mosquitoes of the World is an unmatched resource for entomologists, public health professionals, epidemiologists, and reference libraries.
Chimpanzees, including bonobos and common chimpanzees, are our closest living relatives. However, surprisingly, the information about the soft tissues of bonobos is very scarce, making it difficult to discuss and understand human evolution. This book, which is the first photographic and descriptive musculoskeletal atlas of bonobos (Pan paniscus), adopts the same format as the photographic atlases of other apes previously published by the same authors. These books are part of a series of monographs that will set out the comparative and phylogenetic context of the gross anatomy and evolutionary history of the soft tissue morphology of modern humans and their closest relatives. The present atlas, which includes detailed high quality photographs of the musculoskeletal structures from most anatomical regions of the body as well as textual information about the attachments, innervation, function and weight of the respective muscles, is based on dissections of seven bonobos, including adults, adolescents, infants and fetuses, and males and females, and on an extensive review of the literature for comparisons with common chimpanzees. It therefore provides an updated review of the anatomical variations within chimpanzees as well as an extensive list of synonyms used in the literature to designate the structures covered here. Moreover, contrary to the previous photographic atlases of apes, it also provides details on neurovascular structures such as the brachial and lumbrosacral plexuses. The book will therefore be of interest to students, teachers and researchers focusing on primatology, comparative anatomy, functional morphology, zoology, and physical anthropology and to medical students, doctors and researchers who are curious about the origin, evolution, homology and variations of the musculoskeletal and neurovascular structures of modern humans.
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