A chilling novel of psychological suspense from critically acclaimed and internationally bestselling Swedish author, Marie Hermanson. When Daniel arrives in Himmelstal -- a private Swiss psychiatric facility -- to visit his twin brother Max, he has no idea what's in store for him. He finds himself unquestioningly accepting Max's plea for help and the brothers swap places in order for Max to take care of some business. All he claims to need is a couple of days in the outside world to settle his debt. But soon Daniel realizes Max isn't coming back, and that the clinic is far from a place of recovery. Struggling to get anyone to believe who he really is, Daniel finds himself trapped in a cruel and highly secretive prison: this is no sanctuary, it's a living nightmare . . .
“A fascinating tale of discovery and mystery.” —The Minneapolis Star Tribune In the early 1800's, on a Hebridean beach in Scotland, the sea exposed an ancient treasure cache: 93 chessmen carved from walrus ivory. The Lewis Chessmen are probably the most famous chess pieces in the world. Harry played Wizard's Chess with them in Harry Potter and the Sorcerer's Stone. Housed at the British Museum, they are among its most visited and beloved objects. Questions abounded: Who carved them? Where? Nancy Marie Brown's Ivory Vikings explores these mysteries by connecting medieval Icelandic sagas with modern archaeology, art history, forensics, and the history of board games. In the process, Ivory Vikings presents a vivid history of the 400 years when the Vikings ruled the North Atlantic, and the sea-road connected countries and islands we think of as far apart and culturally distinct: Norway and Scotland, Ireland and Iceland, and Greenland and North America. The story of the Lewis chessmen brings from the shadows an extraordinarily talented woman artist of the twelfth century: Margret the Adroit of Iceland.
The goal of this fascinating new book is to review the diversity of methods available to apply in situ hybridization histochemistry (ISHH) to a variety of experimental questions. This work includes topics such as synthesis and use of nick-translated DNA probes for ISHH, synthesis and use of oligomeric DNA probes for ISHH, and synthesis and use of RNA probes for ISHH. These interesting chapters describe the preparation of different radiolabeled probes for ISHH. They also discuss their respective advantages and limitations, and describe current results based on the use of these various probes. Sections of the text highlight low and high resolution autoradiography for ISHH, the use of biotin-labeled probes for ISHH, as well as the use of ISHH in combination with established anatomical techniques. In Situ Hybridization Histochemistry answers all of your questions regarding the quantification of ISHH. It also provides a practical description of typical protocols, both from molecular biology and histology. Investigators will understand and value this useful, powerful tool-whatever their backgrounds might be.
True, compelling Nebraska stories, including the Roaring '20s, Depression, World War II, and Blizzards of 1949 are narrated by the people who lived them.
This new and important international source of information beings together leading-edge research dedicated to monoclonal antibodies. Monoclonal antibodies (MAbs) are: antibodies of exceptional purity and specificity; components of the immune system; able to recognise and bind to a specific antigen. Monoclonal antibodies are currently utilised in many diagnostic procedures, including: measuring protein and drug levels in serum; typing tissue and blood; identifying infectious agents; identifying clusters of differentiation for the classification and follow-up therapy of leukaemias and lymphomas; identifying tumour antigens and auto-antibodies; identifying the specific cells involved in the immune response; identifying and quantifying hormones. For example, monoclonal antibodies (MABs or MOABs) work on cancer cells in the same way natural antibodies work, by identifying and binding to the target cells. They then alert other cells in the immune system to the presence of the cancer cells. MABs are specific for a particular antigen-one designed for a B-cell lymphoma will not work on cells for ovarian cancer cells for example.
A chilling novel of psychological suspense from critically acclaimed and internationally bestselling Swedish author, Marie Hermanson. When Daniel arrives in Himmelstal -- a private Swiss psychiatric facility -- to visit his twin brother Max, he has no idea what's in store for him. He finds himself unquestioningly accepting Max's plea for help and the brothers swap places in order for Max to take care of some business. All he claims to need is a couple of days in the outside world to settle his debt. But soon Daniel realizes Max isn't coming back, and that the clinic is far from a place of recovery. Struggling to get anyone to believe who he really is, Daniel finds himself trapped in a cruel and highly secretive prison: this is no sanctuary, it's a living nightmare . . .
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