A highly-illustrated, case-based clinical guide for diagnosing and managing adult neuromuscular disease, starting from the case-history to mimic clinical practice.
The Grand River, winding for nearly 300 kilometres through southwestern Ontario, is a Heritage River, its watershed rich in prehistoric, historical and contemporary features. It is important in the history of First Peoples, and the story of European settlement along its banks is a microcosm of that in Canada as a whole. The watershed contains many treasures, such as part of the Carolinian Forest, some of the best farmland in Canada, the spectacular Elora Gorge and a wealth of historic architecture. Far more than that, the Grand is both uniquely itself and also typical of many of the planet’s rivers in the challenges it faces: issues of water management, farmland versus urban development, exploitation of natural resources and restoration of a polluted environment. Each of us lives in a watershed, and this is the story of our world. In the images and words of two artists, The Grand River explores the river’s history, beginning with its formation after the end of the last Ice Age. The book gives insight into the private life of a river—the dialogue of land and water—as well as the ways in which a river interacts with humans, vegetation, wildlife, weather and the planet. It takes the reader on an imaginary journey from the Grand’s first drop of moving water at the source to the point where it flows into Lake Erie.
Parkinson's disease (PD) is characterised by an insidious onset with slowing of emotional and voluntary movement, muscular rigidity, postural abnormality and tremor. Parkinson's disease was first described in 1817 by James Parkinson. It is a progressive, neurological disease mainly affecting people over the age of 50, although at least 10 per cent of cases occur at an earlier age. It affects people of either sex and all ethnic groups. In the normal brain, some nerve cells produce the chemical dopamine, which transmits signals within the brain to produce smooth movement of muscles. In Parkinson's patients, 80 percent or more of these dopamine-producing cells are damaged, dead, or otherwise degenerated. This causes the nerve cells to fire wildly, leaving patients unable to control their movements. This new book brings together the latest research in this field.
There are over 600 neuromuscular disorders and the variability of these syndromes can leave clinicians feeling as if they are lost in a maze as they seek to diagnose and manage patients. This book addresses this problem by using the case-history and symptom manifestation as a starting point for the diagnostic process in adult patients, mimicking the situation in the consultation room. For each case, diagnostic tools, disease pathogenesis, prognosis and treatment options are discussed, along with rare manifestations and differential diagnoses. Symptoms, signs and syndromes are cross-linked to help the reader navigate the variety of disorders. Accompanying tables give a broader picture of the manifestations of a particular disease within the landscape of neuromuscular disorders. This highly-illustrated book, with accompanying videos, will aid neurologists at all levels, internists, geneticists, rehabilitation physicians and researchers in the field, as they seek to familiarize themselves with this complex range of disorders.
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