This issue of Immunology and Allergy Clinics, guest edited by Mariana C. Castells, MD, is devoted to Mastocytosis. Articles in this issue include: New Insight into Clonal Mast Cell Disorders Including Mastocytosis; Cutaneous Mastocytosis in Adults and Children: New Classification and Prognostic Factors; Hymenoptera Anaphylaxis as a Clonal Mast Cell Disorder; Non Clonal Mast Cell Activation Syndrome: A growing body of evidence; Familial Tryptasemia Syndromes: Genotyping and Symptoms; POTS and EDS: Entities Associated to Mast Cell Activation; KIT Mutations: New Insight and Diagnostic Value; Patients’ Perceptions in Mast Cell Activation Disorders; Mast Cell Mediators of Significance in Clinical Practice; Tyrosine Kinase Inhibition in Mast Cell Activation Disorders; Gastrointestinal Involvement in Mast Cell Activation Disorders; Bone Marrow Expression of Mast Cell Disorders; Genomics and Proteonomics in Clonal Mast Cell Disorders; and Pediatric Expression of Mast Cell Activation Disorders.
This issue of Immunology and Allergy Clinics, guest edited by Mariana Castells, is devoted to Drug Hypersensitivity and Desensitizations. Articles in this issue include: Principles and Practice of Drug Desensitization; Incidence and Prevalence of Drug Hypersensitivity; Drug-Induced Anaphylaxis; Penicillin and Beta Lactam Hypersensitivity; Platins Chemotherapy Hypersensitivity: Prevalence and Management; Monoclonal Antibodies Hypersensitivity: Prevalence and Management; Injectable Drugs and MoAbs Reactions and Management with Desensitization; Delayed Cutaneous Reactions to Antibiotics, Management with Desensitization; Management of Children with Hypersensitivity to Antibiotics and MoAbs; Taxenes Hypersensitivity and Management; Progesterone Autoimmune Dermatitis; Severe Delayed Drug Reaction: Role of Genetics and Viral Infections; andAspirin and NSAIDS Hypersensitivity and Management.
Toronto prides itself on being “the world’s most diverse city,” and its officials seek to support this diversity through programs and policies designed to promote social inclusion. Yet this progressive vision of law often falls short in practice, limited by problems inherent in the political culture itself. In Everyday Law on the Street, Mariana Valverde brings to light the often unexpected ways that the development and implementation of policies shape everyday urban life. Drawing on four years spent participating in council hearings and civic association meetings and shadowing housing inspectors and law enforcement officials as they went about their day-to-day work, Valverde reveals a telling transformation between law on the books and law on the streets. She finds, for example, that some of the democratic governing mechanisms generally applauded—public meetings, for instance—actually create disadvantages for marginalized groups, whose members are less likely to attend or articulate their concerns. As a result, both officials and citizens fail to see problems outside the point of view of their own needs and neighborhood. Taking issue with Jane Jacobs and many others, Valverde ultimately argues that Toronto and other diverse cities must reevaluate their allegiance to strictly local solutions. If urban diversity is to be truly inclusive—of tenants as well as homeowners, and recent immigrants as well as longtime residents—cities must move beyond micro-local planning and embrace a more expansive, citywide approach to planning and regulation.
This book develops a new framework for analyzing the spatio-temporal workings of law and other forms of governance. Chronotopes of Law argues that studies of law and governance can be reinvigorated by drawing on a bundle of quite heterogenous analytical tools that do not have a single provenance or a single political or normative aim but that work well in combination. Analyses of legal temporality carried out by anthropologists and studies of law and space undertaken by geographers and legal scholars have proliferated in recent years, but these research traditions have remained largely separate. By adapting notions such as intertextuality, dialogism, and the ‘chronotope’ from Mikhail Bakhtin, notions designed specifically to synthesize considerations of space and time in a framework that is open-ended, interactive and dynamic, Mariana Valverde develops an anti-metaphysical theory and method for legal studies. This approach will be useful both to theorists and to researchers seeking to illuminate the actual workings of law and other forms of governance. Indeed, a key aim of the book is to break down the institutional and disciplinary barriers that prevent theorists from learning from empirical studies and viceversa. Written by one of the foremost sociolegal scholars writing today, this theoretically innovative work constitutes a major contribution to contemporary studies in law and society.
Following the excellent reception of the first two editions of the AC/E Digital Culture Annual Report (2014 and 2015) – more than 5,000 copies of each have been distributed over the past two years – we are pleased to share with culture sector professionals the third edition, which sets out to analyse the impact of new technologies on artistic creation and their use at cultural festivals. To achieve this aim, the broad-ranging content of the third edition of the report has been divided into two main sections to make it easier to read for the different audiences at which it is aimed. 'Smart Culture' is the overarching theme established by the Advisory Committee of the AC/E Digital Culture Annual Report 2016 as a basis for choosing the six articles that make up the first part of this year's edition. Just as the first report's Focus dealt with the impact of the Internet on the performing arts (theatre, opera, dance, ballet, etc.) and that of the second edition analysed the use of new technologies in the world of museums, for this third edition it conducts a thorough analysis of the use of new technologies at some 50 Spanish and foreign cultural festivals.
This issue of Immunology and Allergy Clinics, guest edited by Mariana C. Castells, MD, is devoted to Mastocytosis. Articles in this issue include: New Insight into Clonal Mast Cell Disorders Including Mastocytosis; Cutaneous Mastocytosis in Adults and Children: New Classification and Prognostic Factors; Hymenoptera Anaphylaxis as a Clonal Mast Cell Disorder; Non Clonal Mast Cell Activation Syndrome: A growing body of evidence; Familial Tryptasemia Syndromes: Genotyping and Symptoms; POTS and EDS: Entities Associated to Mast Cell Activation; KIT Mutations: New Insight and Diagnostic Value; Patients’ Perceptions in Mast Cell Activation Disorders; Mast Cell Mediators of Significance in Clinical Practice; Tyrosine Kinase Inhibition in Mast Cell Activation Disorders; Gastrointestinal Involvement in Mast Cell Activation Disorders; Bone Marrow Expression of Mast Cell Disorders; Genomics and Proteonomics in Clonal Mast Cell Disorders; and Pediatric Expression of Mast Cell Activation Disorders.
This issue of Immunology and Allergy Clinics, guest edited by Mariana Castells, is devoted to Drug Hypersensitivity and Desensitizations. Articles in this issue include: Principles and Practice of Drug Desensitization; Incidence and Prevalence of Drug Hypersensitivity; Drug-Induced Anaphylaxis; Penicillin and Beta Lactam Hypersensitivity; Platins Chemotherapy Hypersensitivity: Prevalence and Management; Monoclonal Antibodies Hypersensitivity: Prevalence and Management; Injectable Drugs and MoAbs Reactions and Management with Desensitization; Delayed Cutaneous Reactions to Antibiotics, Management with Desensitization; Management of Children with Hypersensitivity to Antibiotics and MoAbs; Taxenes Hypersensitivity and Management; Progesterone Autoimmune Dermatitis; Severe Delayed Drug Reaction: Role of Genetics and Viral Infections; andAspirin and NSAIDS Hypersensitivity and Management.
Despite wide recognition as a serious public health problem, anaphylaxis and hypersensitivity reactions remain under-recognized and under-diagnosed. This book fills the gaps in our understanding of the identification of triggers, recognition of clinical presentations, understanding of the natural history of these reactions, and selection of treatment strategies including those focused on cellular and molecular targets. The book provides a detailed examination of disease etiology, pathogenesis, and pathophysiology and their correlation to clinical practice. Forefront knowledge of the mediators and mechanisms of anaphylaxis is covered with an emphasis on how new discoveries shape our current and emerging therapies.
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