Born in 1915 to one of New England’s elite wealthy families, Isabella Gardner was expected to follow a certain path in life—one that would take her from marriageable debutante to proper society lady. But that plan was derailed when at age eighteen, Isabella caused a drunk-driving accident. Her family, to shield her from disgrace, sent her to Europe for acting studies, not foreseeing how life abroad would fan the romantic longings and artistic impulses that would define the rest of Isabella’s years. In Not at All What One Is Used To, author Marian Janssen tells the story of this passionate, troubled woman, whose career as a poet was in constant compromise with her wayward love life and her impulsive and reckless character. Life took Gardner from the theater world of the 1930s and ’40s to the poetry scene of the ’50s and ’60s to the wild, bohemian art life of New York’s Hotel Chelsea in the ’70s. She often followed where romance, rather than career, led her. At nineteen, she had an affair with a future president of Ireland, then married and divorced three famous American husbands in succession. Turning from acting to poetry, Gardner became associate editor of Chicago’s Poetry magazine and earned success with her best-received collection, Birthdays from the Ocean, in 1955. Soon after, her life took a turn when she met the southern poet Allen Tate. He was married to Caroline Gordon but left her to wed Gardner, who moved to Minneapolis and gave up writing to please him, but after a few short years, Tate fell for a young nun and abandoned her. In the liveliest of places at the right times, Gardner associated with many of the most significant cultural figures of her age, including her cousin Robert Lowell, T.S. Eliot, Ludwig Mies van der Rohe, Virgil Thomson, Tennessee Williams, and Robert Penn Warren. But famous connections could never save Isabella from herself. Having abandoned her work, she suffered through alcoholism, endured more failed relationships, and watched the lives of her children unravel fatally. Toward the end of her life, though, she took her pen back up for the poems in her final volume. Redeemed by her writing, Gardner died alone in 1981, just after being named the first poet laureate of New York State. Through interviews with many Gardner intimates and extensive archival research, author Marian Janssen delves deep into the life of a woman whose poetry, according to one friend, “probably saved her sanity.” Much more than a biography, Not at All What One Is Used To is the story of a woman whose tumultuous life was emblematic of the cultural unrest at the height of the twentieth century.
Application of scientific findings to effective practice and informed policymaking is an aspiration for much research in the biomedical, behavioural, and developmental sciences. But too often translations of science to practice are conceptually narrow, ethically underspecified, and developed quickly as salves to an urgent problem. For developmental science, widely implemented parenting interventions are prime examples of technical translations from knowledge about the causes of children’s mental distress. Aiming to support family relationships and facilitate adaptive child development, these programmes are rushed through when the scientific findings on which they are based remain contested and without ethical grounding of their aims. In Matters of Significance, Marinus van IJzendoorn and Marian Bakermans-Kranenburg draw on 40 years of experience with theoretical, empirical, meta-analytic and translational work in child development research to highlight the complex relations between replication, translation and academic freedom. They argue that challenging fake facts promulgated by under-replicated and under-powered studies is a critical type of translation beyond technical applications. Such challenges can, in the highlighted field of attachment and emotion regulation research, bust popular myths about the decisive role of genes, hormones, or the brain on parenting and child development, with a balancing impact for practice and policymaking. The authors argue that academic freedom from interference by pressure groups, stakeholders, funders, or university administrators in the core stages of research is a necessary but besieged condition for adversarial research and myth busting. Praise for Matters of Significance ‘This thoughtful volume is an accessible overview of the authors’ field-shaping collaborative research on attachment and an indispensable primer on differentiating between sense and nonsense in the service of producing cumulative developmental science and ethically translating its core insights.’ Glenn I. Roisman, University of Minnesota ‘The truly original arguments presented in Matters of Significance go beyond attachment, as they concern the nature of developmental science and its relation to ethical, cultural, legal and political issues.’ Jay Belsky, University of California, Davis
Pressure is one of the essential thermodynamic variables that, due to some former experimental difficulties, was long known as the “forgotten variable.” But this has changed over the last decade. This book includes the most essential first experiments from the 1960's and reviews the progress made in understanding glass formation with the application of pressure in the last ten years. The systems include amorphous polymers and glass-forming liquids, polypeptides and polymer blends. The thermodynamics of these systems, the relation of the structural relaxation to the chemical specificity, and their present and future potential applications are discussed in detail. The book provides (a) an overview of systems exhibiting glassy behavior in relation to their molecular structure and provides readers with the current state of knowledge on the liquid-to-glass transformation, (b) emphasizes the relation between thermodynamic state and dynamic response and (c) shows that the information on the pressure effects on dynamics can be employed in the design of materials for particular applications. It is meant to serve as an advanced introductory book for scientists and graduate students working or planning to work with dynamics. Several scientific papers dealing with the effects of pressure on dynamics have appeared in leading journals in the fields of physics in the last ten years. The book provides researchers and students new to the field with an overview of the knowledge that has been gained in a coherent and comprehensive way.
This open access book provides teachers with approaches to strengthen reading comprehension instruction based on scientific research and evidence-based didactic principles. In this volume, the Progress in International Reading Study (PIRLS) framework is used to inform teachers about the skills and knowledge that students need to comprehend certain texts. The book gives practical guidance on how a teacher can help students to learn these skills, specifically, when teaching reading to multilingual students. Good practices from schools in five participating PIRLS countries -- Chile, Chinese Taipei, England, Georgia, and Spain -- are shared. A description of the schools' education in reading comprehension is provided with practical tips and example lessons. These insights into daily reading education in multilingual classrooms across the globe can be an inspiration to teachers all over the world.
This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.
The need to understand and quantify change is fundamental throughout the environmental sciences. This might involve describing past variation, understanding the mechanisms underlying observed changes, making projections of possible future change, or monitoring the effect of intervening in some environmental system. This book provides an overview of modern statistical techniques that may be relevant in problems of this nature. Practitioners studying environmental change will be familiar with many classical statistical procedures for the detection and estimation of trends. However, the ever increasing capacity to collect and process vast amounts of environmental information has led to growing awareness that such procedures are limited in the insights that they can deliver. At the same time, significant developments in statistical methodology have often been widely dispersed in the statistical literature and have therefore received limited exposure in the environmental science community. This book aims to provide a thorough but accessible review of these developments. It is split into two parts: the first provides an introduction to this area and the second part presents a collection of case studies illustrating the practical application of modern statistical approaches to the analysis of trends in real studies. Key Features: Presents a thorough introduction to the practical application and methodology of trend analysis in environmental science. Explores non-parametric estimation and testing as well as parametric techniques. Methods are illustrated using case studies from a variety of environmental application areas. Looks at trends in all aspects of a process including mean, percentiles and extremes. Supported by an accompanying website featuring datasets and R code. The book is designed to be accessible to readers with some basic statistical training, but also contains sufficient detail to serve as a reference for practising statisticians. It will therefore be of use to postgraduate students and researchers both in the environmental sciences and in statistics.
The hereditary retinopathy, retinitis pigmentosa (RP), which affects 1 in 3,500 people worldwide, is the most common cause of registered visual handicap among those of the working age in developed countries. RP is a highly variable disorder where patients may develop symptomatic visual loss in early childhood, while others may remain asymptomatic until mid-adulthood. Most cases of RP segregate in autosomal dominant, recessive or X-linked recessive modes, with approximately 41 genes being implicated in disease pathology to date (RetNet). The extensive genetic heterogeneity associated with autosomal dominant RP (adRP) is an undisputed hindrance to the development of genetically based therapeutics.
The seven essays included in this volume move beyond the famed Ashcan School to recover the lesser known work of Robert Henri's women students. The contributors, who include well-known scholars of art history, American studies, and cultural studies demonstrate how these women participated in the "modernizing" of women's roles during this era.
A pioneering forecaster predicts the trends and technologies that will shape global culture and commerce in the next two decades—a must-read guide for business leaders, entrepreneurs, and anyone looking for an edge. “In a world of half-baked hot takes, Marian Salzman is a true seer.”—Andrew Yang A little more than twenty years ago, the Y2K computer glitch threatened to bring the global economy to its knees. But instead of overnight disruption, humankind slipped into two decades of economic turmoil, ecological angst, and tribalism, all set against the backdrop of a newly global and digital civilization. Sometimes the events that seem pivotal are just blips, while the more meaningful cultural shifts are hiding in plain sight. Marian Salzman’s job is to uncover those hidden shifts. So what’s in store for the next two decades? In this acutely observed guide, Salzman, whose past predictions have been heralded for coming uncannily close to the way we live now, unpacks the course of human life from the bumpy turn of the millennium through the pandemic era, when chaos and “together apart” are the new normal, equity has become a battle cry, and breathing space emerged as the greatest luxury of all. Drawing inspiration from John Naisbitt’s classic 1982 book Megatrends, Salzman then turns to the two decades ahead. Navigating deftly among geographies, she connects threads across business, civic life, consumerism, family, and entertainment, revealing the trends and developments—some established, some surprising—poised to recast our past, shape our collective future, and shift our identities. In a world dominated by disruption, being prepared for change is a critical advantage. The New Megatrends is gripping reading for anyone seeking to understand the shape and texture of the next era, which, above all, will be marked by its relentless pace, new technology, and the ever-present threats of climate change and political division.
Clinical Nutrition for Surgical Patients, Third Edition, is the most comprehensive resource available for practitioners who offer interdisciplinary nutrition care to surgical patients. This reference begins with a through review of the basics of medical nutrition therapy for surgical patients, including nutritional assessment, the role of surgical diets, and the indications and contraindications for specialized nutrition support. Subsequent chapters, written by experts in the field, address specific medical and surgical conditions and disease states that present specific challenges with provision of nutrition support. All recommendations are evidence-based and can be applied to clinical practice. The latest nutrition support techniques are described and their roles in managing many types of surgical patients are outlined. Any clinician caring for surgical patients will benefit from the wealth of current information provided in this text.
Want to speak Hittite? Hold out a glass and ask for &“wa-tar.&” This unique activity book for children ages nine and up shows what life was like among the Nubians, Mesopotamians, Hittites, and their neighbors the Egyptians from around 3100 B.C., when Upper and Lower Egypt became one kingdom, to the death of Queen Cleopatra under the Romans, in 30 B.C. Projects such as building a Nubian irrigation machine, creating a Mesopotamian cylinder seal out of clay, making kilts like those worn by Egyptian boys and men, and writing in Hittite cuneiform help young readers to connect with these ancient cultures and see how profoundly they have influenced our own.
During the fourteenth and thirteenth centuries BCE, the kings of Egypt, Babylonia, Assyria, and Hatti participated in a complex international community. These two hundred years also witnessed the production of luxurious artworks made of gold, ivory, alabaster, and faience--objects that helped to foster good relations among the kingdoms. In fact, as Marian H. Feldman makes clear here, art and international relations during the Late Bronze Age formed an unprecedented symbiosis, in concert with expanded travel and written communications across the Mediterranean. And thus diplomacy was invigorated through the exchange of lavish art objects and luxury goods, which shared a repertoire of imagery that modern scholars have called the first International Style in the history of art. Previous studies have focused almost exclusively on stylistic attribution of these objects at the expense of social contextualization. Feldman's Diplomacy by Design instead examines the profound connection between art produced during this period and its social and political contexts, revealing inanimate objects as catalysts--or even participants--in human dynamics. Feldman's fascinating study shows the ways in which the diplomatic circulation of these works actively mediated and strengthened political relations, intercultural interactions, and economic negotiations and she does so through diverse disciplinary frameworks including art history, anthropology, and social history. Written by a specialist in ancient Near Eastern art and archaeology who has excavated and traveled extensively in this area of the world, Diplomacy by Design considers anew the symbolic power of material culture and its centrality in the construction of human relations.
Born in 1915 to one of New England’s elite wealthy families, Isabella Gardner was expected to follow a certain path in life—one that would take her from marriageable debutante to proper society lady. But that plan was derailed when at age eighteen, Isabella caused a drunk-driving accident. Her family, to shield her from disgrace, sent her to Europe for acting studies, not foreseeing how life abroad would fan the romantic longings and artistic impulses that would define the rest of Isabella’s years. In Not at All What One Is Used To, author Marian Janssen tells the story of this passionate, troubled woman, whose career as a poet was in constant compromise with her wayward love life and her impulsive and reckless character. Life took Gardner from the theater world of the 1930s and ’40s to the poetry scene of the ’50s and ’60s to the wild, bohemian art life of New York’s Hotel Chelsea in the ’70s. She often followed where romance, rather than career, led her. At nineteen, she had an affair with a future president of Ireland, then married and divorced three famous American husbands in succession. Turning from acting to poetry, Gardner became associate editor of Chicago’s Poetry magazine and earned success with her best-received collection, Birthdays from the Ocean, in 1955. Soon after, her life took a turn when she met the southern poet Allen Tate. He was married to Caroline Gordon but left her to wed Gardner, who moved to Minneapolis and gave up writing to please him, but after a few short years, Tate fell for a young nun and abandoned her. In the liveliest of places at the right times, Gardner associated with many of the most significant cultural figures of her age, including her cousin Robert Lowell, T.S. Eliot, Ludwig Mies van der Rohe, Virgil Thomson, Tennessee Williams, and Robert Penn Warren. But famous connections could never save Isabella from herself. Having abandoned her work, she suffered through alcoholism, endured more failed relationships, and watched the lives of her children unravel fatally. Toward the end of her life, though, she took her pen back up for the poems in her final volume. Redeemed by her writing, Gardner died alone in 1981, just after being named the first poet laureate of New York State. Through interviews with many Gardner intimates and extensive archival research, author Marian Janssen delves deep into the life of a woman whose poetry, according to one friend, “probably saved her sanity.” Much more than a biography, Not at All What One Is Used To is the story of a woman whose tumultuous life was emblematic of the cultural unrest at the height of the twentieth century.
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