Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease. - Over 145 full-color illustrations of the molecular and cellular cascades underlying the disease pathology. - Disease pathways are based on computational models from Elsevier's Disease Pathway Collection, published for the first time outside of Pathway Studio® commercial software. - Each relationship on the pathway models is supported by references to scientific articles and can be examined at freely available online resources.
There is a growing need for better membranes in several emerging application fields especially those related to energy conversion and storage as well as to water treatment and recycling. Processability, is an important functional property, often ignored, especially in the early discovery phase for new materials, but it should be one of the most important properties, that needs to be considered in the development of better membrane materials. Useful membrane materials have to be capable of being formed into thin membranes, in particular for membrane gas separation, water treatment and desalination, and then packaged, into large area membrane modules. All gas separation membranes that are in current commercial use are based on polymers, which are solution-processable. This book intends to deal with composite, in most cases hybrid polymer-based membranes for three separate application fields: energy conversion, energy storage and water treatment and recovery. Each chapter will explain clearly the various membrane processes then go on to discuss in detail the corresponding advanced membranes used. The logic that lies behind this is that you have to understand the process in order to develop new high-performance membranes. By taking this approach, the author aims to overcome the disconnection that currently exists between membrane materials scientists and industrial process engineers. - Discusses interdisciplinary content by a single author, approaching synthesis and development of materials from the perspective of their processability - Describes the novel aspects of membrane science that is related to energy storage, conversion and wastewater treatment - Presents an emphasis on scientific results which have an impact on real applications in terms of renewable and clean energy challenges
Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease. - Over 145 full-color illustrations of the molecular and cellular cascades underlying the disease pathology. - Disease pathways are based on computational models from Elsevier's Disease Pathway Collection, published for the first time outside of Pathway Studio® commercial software. - Each relationship on the pathway models is supported by references to scientific articles and can be examined at freely available online resources.
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