Humans are exposed daily to low concentrations of metals that are released into the environment by both natural and industrial processes. Environmental Metal Pollutants, Reactive Oxygen Intermediaries and Genotoxicity: Molecular Approaches to Determine Mechanisms of Toxicity examines concerns about the acute and/or chronic exposure of humans to concentrations of these metals that are below the threshold levels established by various federal regulatory agencies. Some of these metals are accumulated in various tissues and over time this may result in the accumulation of a significant body burden. This could increase the risk of developing a variety of diseases later in life, at a time when thresholds for such effects may already be reduced by the processes of aging. Such possibilities could only further compromise the quality of life in the elderly population and could contribute to the rising cost of health care in this country. Studies that have been conducted to determine the possible risks associated with exposure to relatively non-toxic concentrations of environmental metals have been hampered by a lack of appropriate models and a lack of funding. It has also been difficult for researchers to demonstrate a correlation between the exposure of humans or animals to low concentrations of environmental pollutants and disease. This book examines recent technological advances in the areas of molecular biology, biochemistry, and computer-enhanced image analyses that provide researchers with the tools to begin elucidating the genotoxic effects of environmental metal pollutants and the mechanisms by which these metals cause DNA damage. Environmental Metal Pollutants, Reactive Oxygen Intermediaries and Genotoxicity: Molecular Approaches to Determine Mechanisms of Toxicity presents data that demonstrate that certain environmental metal pollutants are genotoxic. The authors describe the role of reactive oxygen intermediates in causing the DNA damage induced by environmental metal pollutants and discuss their possible role in human disease.
How has technology changed the art and science of nursing practice?Many facets of nursing practice have stayed constant over the years such as the way we advocate for our patients and the art of caring for our patients. However, nursing practice has evolved over the years especially in the bedside delivery of state of the art nursing care. Technology at the bedside has forced nurse educators to change the ways in which we always have taught nursing students. Technology has also begun to change the methods used in the actual bedside nursing care. In this issue, you will hear from some of the nursing experts in areas of nursing care that has changed in either the delivery of care or method of assessing care of the patient. Nursing experts will describe some of the historical changes and intrigue you in the changes expected to come to the bedside. Why is this issue important? First, we gain insight from a review of where we have been and nurses tend to reminisce on our past as well as romance our historical roots. Second, technology is ever changing and it is good practice to keep abreast of what is happening in other areas of nursing so that we can apply others successes in our own specific areas of nursing. Third, informatics in nursing is a growing field and nursing must embrace technology and learn to adapt various methods of delivery so that we can appropriately care for and advocate for our patients.With the changes in our national healthcare system, we must encourage nurses to try out new methods of delivery as well as encourage their ideas of how nursing can change. The articles in this issue reflect these changes.
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