Margaret M. McCarthy's Books

Sex and the Developing Brain

Second Edition

By: Margaret M. McCarthy

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The brains of males and females, men and women, are different, that is a fact. What is debated is how different and how important are those differences. Sex differences in the brain are determined by genetics, hormones, and experience, which in humans includes culture, society, and parental and peer expectations. The importance of nonbiological variables to sex differences in humans is paramount, making it difficult if not impossible to parse out those contributions that are truly biological. The study of animals provides us the opportunity to understand the magnitude and scope of biologically based sex differences in the brain, and understanding the cellular mechanisms provides us insight into novel sources of brain plasticity. Many sex differences are established during a developmental sensitive window by differences in the hormonal milieu of males versus females. The neonatal testis produces large amounts of testosterone which gains access to the brain and is further metabolized into active androgens and estrogens which modify brain development. Major parameters that are influenced by hormones include neurogenesis, cell death, neurochemical phenotype, axonal and dendritic growth, and synaptogenesis. Variance in these parameters results in sex differences in the size of particular brain regions, the projections between brain regions, and the number and type of synapses within particular brain regions. The cellular mechanisms are both region and endpoint specific and invoke many surprising systems such as prostaglandins, endocannabinoids, and cell death proteins. Epigenetic modifications to the genome both establish and maintain sex differences in the brain and behavior. By understanding when, why, and how sex differences in the brain are established, we may also learn the source of strong gender biases in the relative risk and severity of numerous neurological diseases and disorders of mental health. Boys are much more likely to be diagnosed with autism spectrum or attention and hyperactivity disorders, as well as speech and language deficits, compared to girls. By contrast, women are more likely to suffer from affective disorders, such as depression, anxiety, compulsion, and eating disorders and more likely to experience autoimmune and neurodegenerative disorders. Schizophrenia with an early onset is more common in males but a late-onset version is markedly more frequent in females. Male biased disorders have origins in development while female biased disorders are almost exclusively post-puberty. This remarkable shift in disease risk demands our attention. Novel insights into the biological origins of disease are also gained by comparing and contrasting the same processes in different sexes.

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Page Count

156

Publisher

Biota Publishing

Published Date

ISBN 10

1615047298

ISBN 13

9781615047291

Emergency and Trauma Care for Nurses and Paramedics - eBook

By: Kate Curtis,Clair Ramsden,Ramon Z. Shaban,Margaret Fry,Julie Considine

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Emergency and Trauma Care for Nurses and Paramedics - eBook

By: Kate Curtis,Clair Ramsden,Ramon Z. Shaban,Margaret Fry,Julie Considine

- Expanded editorial team, all internationally recognised researchers and leaders in Emergency Care - Chapter 6 Patient safety and quality care in emergency - All chapters revised to reflect the most up-to-date evidence-based research and practice - Case studies and practice tips highlight cultural considerations and communication issues - Aligns to NSQHSS 2e, NMBA and PBA Standards - An eBook included in all print purchases

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Page Count

1502

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0729587193

ISBN 13

9780729587198

Community Development in Action

Putting Freire Into Practice

By: Margaret Ledwith

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Community Development in Action

Putting Freire Into Practice

By: Margaret Ledwith

In a world in which social divisions are widening not lessening, it is essential for community development, or any other practice committed to social justice and sustainability, to understand how power works at every level, from grassroots projects to movements for change. This exciting and practical book is filled to the brim with useful ideas for busy practitioners. Building on the work of Paulo Freire, theories are presented in interesting and straightforward ways to provide an everyday reference for practice. Contained in these pages is all you need to give your practice a critical edge!

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Page Count

208

Publisher

Policy Press

Published Date

ISBN 10

1847428754

ISBN 13

9781847428752

Continuing Professional Development in Social Work

By: Halton, Carmel,Powell, Fred,Margaret Scanlon

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Continuing Professional Development in Social Work

By: Halton, Carmel,Powell, Fred,Margaret Scanlon

Continuing professional development has become an important and widespread practice in twenty-first-century social work. This volume traces its emergence and evolution, identifying the characteristics of continuing professional development, the barriers to undertaking it, and the way social workers view it. Drawing on an international survey of practitioners and interviews with social workers and their managers, the authors provide unique insight into the possibilities and challenges of continuing professional development for newly qualified and experienced social workers alike.

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Page Count

232

Publisher

Policy Press

Published Date

ISBN 10

1447307380

ISBN 13

9781447307389

Nutrition & Dietetics

Practice and Future Trends

By: Esther A. Winterfeldt,Margaret L. Bogle,Lea L. Ebro

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Nutrition & Dietetics

Practice and Future Trends

By: Esther A. Winterfeldt,Margaret L. Bogle,Lea L. Ebro

This text provides an overview of the career opportunities for dietitians, explaining what they do, highlighting the specific areas of dietetic practice, and listing the requirements to become a dietitian."--Back cover.

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Page Count

290

Publisher

Jones & Bartlett Publishers

Published Date

ISBN 10

1449679048

ISBN 13

9781449679040

Rockwood and Green's Fractures in Adults

By: Charles Court-Brown,James D. Heckman,Michael McKee,Margaret M. McQueen,William Ricci,Paul Tornetta, III

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Rockwood and Green's Fractures in Adults

By: Charles Court-Brown,James D. Heckman,Michael McKee,Margaret M. McQueen,William Ricci,Paul Tornetta, III

Need the go-to reference on adult bone and joint injuries? Get the definitive guide on fracture treatment, written by the world’s top orthopaedic surgeons: Rockwood and Green’s Fractures in Adults. This fully updated and expanded 8th edition offers up-to-the-minute research and recommendations from more than 80 leading orthopaedic experts from around the world. An essential resource on fractures for every orthopaedic surgeon or resident.. Features: NEW chapters on: Management of the Geriatric or Elderly Patient; Management of Bone Defects;; Psychological Aspect of Trauma NEW authors from countries including India, China, Columbia, Greece, and Denmark NEW 10 new full length videos added to the video library. All videos feature easy navigation so you can go directly to specific steps in the procedure, or watch the entire procedure from start to finish Pearls and Pitfalls and preventive measures listed for all procedures NEW Time-saving outline template for easy quick-reference “Before the Case” checklists of all necessary equipment for each surgical procedure Preferred Technique section provides algorithms explaining each author’s choice of preferred procedure Full-color operative photos, tables, x-rays, diagrams, and more than 500 line drawings of surgical procedures

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Page Count

6127

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1469884828

ISBN 13

9781469884820

Book's by Margaret M. McCarthy

Sex and the Developing Brain

Sex and the Developing Brain

Emergency and Trauma Care for Nurses and Paramedics - eBook

Emergency and Trauma Care for Nurses and Paramedics - eBook

Community Development in Action

Community Development in Action

Continuing Professional Development in Social Work

Continuing Professional Development in Social Work

Nutrition & Dietetics

Nutrition & Dietetics

Rockwood and Green's Fractures in Adults

Rockwood and Green's Fractures in Adults

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