An up-to-date overview of the field of connectomics, introducing concepts and mechanisms underlying brain network change at different stages. The human brain undergoes massive changes during its development, from early childhood and the teenage years to adulthood and old age. Across a wide range of species, from C. elegans and fruit flies to mice, monkeys, and humans, information about brain connectivity (connectomes) at different stages is now becoming available. New approaches in network neuroscience can be used to analyze the topological, spatial, and dynamical organization of such connectomes. In Changing Connectomes, Marcus Kaiser provides an up-to-date overview of the field of connectomics and introduces concepts and mechanisms underlying brain network changes during evolution and development.
This book, an authoritative text on musculoskeletal and physical medicine that integrates Eastern and Western approaches, covers every aspect of musculoskeletal medicine, starting with an in depth introduction to Traditional Chinese Medicine (TCM) principles as they relate to the subject. Author Alon Marcus surveys the science of pain from both modern biomedical and TCM perspectives, examines the foundations of integrative musculoskeletal medicine, explores biomedical and osteopathic clinical assessment, and outlines treatment options such as acupuncture, blood-letting, and meridian therapy. Other chapters analyze herbal medicine, integrative electrotherapeutics, manual therapy, and much more.
An Introduction to Universal Artificial Intelligence provides the formal underpinning of what it means for an agent to act intelligently in an unknown environment. First presented in Universal Algorithmic Intelligence (Hutter, 2000), UAI offers a framework in which virtually all AI problems can be formulated, and a theory of how to solve them. UAI unifies ideas from sequential decision theory, Bayesian inference, and algorithmic information theory to construct AIXI, an optimal reinforcement learning agent that learns to act optimally in unknown environments. AIXI is the theoretical gold standard for intelligent behavior. The book covers both the theoretical and practical aspects of UAI. Bayesian updating can be done efficiently with context tree weighting, and planning can be approximated by sampling with Monte Carlo tree search. It provides algorithms for the reader to implement, and experimental results to compare against. These algorithms are used to approximate AIXI. The book ends with a philosophical discussion of Artificial General Intelligence: Can super-intelligent agents even be constructed? Is it inevitable that they will be constructed, and what are the potential consequences? This text is suitable for late undergraduate students. It provides an extensive chapter to fill in the required mathematics, probability, information, and computability theory background.
Migraine is an extremely common condition affecting 28 million Americans. Fully 1 in every 6 adult women suffers from this malady. Patients with migraine are frequently seen in the Emergency Room and Urgent Care Clinic for acute treatment of their headaches. Headache generally accounts for nearly 3 % of all ER visits, resulting in almost 3.5 million visits annually. There currently are no widely used guidelines for the treatment of patients with headache in the ER or UCC, and reducing the number of CT scans remains a key goal for administrators in many ER or urgent care settings. In one study, 35 drugs, alone or in combination, were used to treat migraine. The most common medication class used was narcotics, which were used in 25% of the visits. The next two most commonly used classes were antiemetics and NSAIDs. Only 5% of patients seen for headache received headache-specific medications during their visit. ER and Urgent Care physicians generally have little or no formal training in treating these patients. Consequently, they often feel less comfortable ruling out secondary causes of headaches and using appropriate headache treatment medications and procedures. Since many patients have received narcotics in previous visits, providers may view them as drug seekers. Patients seen in ERs and UCCs for acute treatment of their headaches often report high levels of dissatisfaction. They often end up in the ER or UCC because they don’t have a formal treatment strategy for their severe headaches. Health plans and insurance agencies are often frustrated by the high cost of fragmented care for patients with headaches. Because of the environment that most ER and UCC providers operate in, many unnecessary scans and tests are done because of uncertainty of the diagnosis and unfamiliarity of the patient. Primary care physicians are also frustrated by patients with headaches presenting to them after being seen in the ER or UCC, wanting a refill of their narcotics that they were given. Many patients don’t follow up with their PCPs and simply keep returning to the ER/UCC for their treatment. In short, all involved in the care for patients with headache are frustrated by the current system. The care for these patients is clearly not optimal. It doesn’t have to be that way. There are a wide variety of effective treatment options available, but are underutilized in the acute setting. With these treatment options, patients no longer have to be treated only with parenteral narcotics, only to perpetuate the cycle of suboptimal care described above. This concise handbook covers all aspects of acute headache care, including care of the child and adolescent with acute headaches, treatment of pregnant and breastfeeding women with acute headaches and appropriate evaluation of secondary headaches. In addition, two other novel chapters are included: one on caring for older patients with acute headaches as well as a chapter describing how to ensure a seamless transition of the patient back to a headache interested provider. Representing an important milestone in the care of patients with headache, this is the first concise handbook available to exclusively address the issue of headache treatment in the acute care setting. Including protocols and strategies that can be used right away, Management of Headaches in Emergency Room and Urgent Care Settings: Diagnosis and Management provides information about lesser known, but effective strategies such as greater occipital nerve blocks that can be easily learned and incorporated in the acute care setting. It emphasizes the continuity of care that is so vital to keep headache patients from returning to the ER and UCC for acute treatment.
This is one of the first books fully dedicated to the rapidly advancing and expanding research area of deep eutectic solvents. Written by the internationally recognized expert in solution chemistry, it supplies full information regarding preparation of these new eco-friendly solvents, their properties and applications. The current and potential applications of deep eutectic solvents as organic reaction media, catalytic system, in biomass processing, nanotechnology and metal finishing industry, as well as for extraction and separation are extensively discussed.This highly informative and carefully presented book will appeal to practicing chemists (organic chemists, polymer chemists, biochemists) as well as chemical engineers and environmental scientists.
More than 28 million Americans suffer from migraine headaches, with migraine affecting nearly one in five women in their reproductive years. Effective Migraine Treatment in Pregnant and Lactating Women: A Practical Guide, provides a comprehensive resource to address diagnosis, testing, and treatment of headaches in reproductively fertile women. This important new book offers a wealth of practical, ready-to-use, clinically tested tips and recommendations to treat women with headaches during pregnancy and nursing. Although women may ideally prefer to restrict migraine treatments during pregnancy, up to one in three pregnant women self-medicate for symptoms, especially with analgesics. Fortunately, there are many effective treatment options that can be safely used when pregnant and breastfeeding. Available therapies include medication and nonmedication treatments, traditional and alternative therapies, and nutritional supplements. This book uniquely answers frequently asked questions by patients and offers healthcare providers easy-to-use office tools for patient education and charting documentation. The authors of this important new work have collaborated to provide a resource that will help clinicians provide women with the tools and knowledge to become empowered and to gain control over their migraines when trying to conceive, during pregnancy, and when nursing.
Today, multidisciplinary approaches to treatment are at the heart of cancer care. They offer improved clinical outcomes, new possibilities in patient quality of life, and enable the development of true innovation in individualized treatment. To accurately reflect this modern day approach to cancer care, the content of the 6th edition of Principles and Practice of Gynecologic Oncology was written entirely by surgeons, medical oncologists, radiation oncologists, and pathologists. New to the editorial team, Dr. Andrew Berchuck has made significant contributions to the understanding of the molecular pathogenesis of ovarian and endometrial cancer in the book’s content. Every chapter of this book has been either completely rewritten or extensively updated to ensure that everyone involved in treating women with gynecologic cancer will have the most comprehensive and up-to-date information on the subject.
The formal sciences, particularly mathematics, have had a profound influence on the development of linguistics. This insightful overview looks at techniques that were introduced in the fields of mathematics, logic and philosophy during the twentieth century, and explores their effect on the work of various linguists. In particular, it discusses the 'foundations crisis' that destabilised mathematics at the start of the twentieth century, the numerous related movements which sought to respond to this crisis, and how they influenced the development of syntactic theory in the 1950s. The book concludes by discussing the resulting major consequences for syntactic theory, and provides a detailed reassessment of Chomsky's early work at the advent of Generative Grammar. Informative and revealing, this book will be invaluable to all those working in formal linguistics, in particular those interested in its history and development.
Chapters that are new or radically changed include the opening chapter on the Health Needs of Women in a Changing Society; Teaching and Learning Surgical Techniques; and chapters on Minimal Access Surgery, which are richly illustrated by remarkable photographic images. Chapters on Pelvic Floor and Cancer Surgery retain well-established operative procedures where relevant, but include accounts of exciting newer techniques, such as robotic surgery. Up to the minute chapters on Radiology, Radiotherapy and Chemotherapy are provided by colleagues from these specialties who now form part of modern multidisciplinary teams. The 6th Edition, which appeared in 2001, reflected the growing replacement of conventional abdominal and vaginal surgery with radiological interventions, endoscopic surgery and medical treatments. The last 10 years have seen worldwide acceptance of the benefits of less invasive gynaecological procedures, allowing ever shorter stay in hospital and quicker recovery for the patient, but often with the use of much more expensive and complex technological equipment. At the same time, there has been an increasing trend towards super-specialisation so that in many parts of the world gynaecologists focus on a narrower field of activity. Specialists need to be aware of these developments even though the individual gynaecologist may carry out only a limited range of operations or therapies. The structure of the book has been changed radically, separating benign from malignant conditions, congenital from acquired, and with a strong emphasis on patient choice, safety and prevention of complications.
When the four of us decided to collaborate to write this book on pneumatic conveying, there were two aspects which were of some concern. Firstly, how could four people, who liveon four different continents, write a book on a fairly complex subject with such wide lines of communications? Secondly, there was the problem that two of the authors are chemical engineers.It has been noted that the majority of chemical engineers who work in the field of pneumatic conveying research have spent most of their time considering flow in vertical pipes. As such, there was some concern that the book might be biased towards vertical pneumatic conveying and that the horizontal aspects (which are clearly the most difficult!) would be somewhat neglected. We hope that you, as the reader, are going to be satisfied with the fact that you have a truly international dissertation on pneumatic conveying and, also, that there is an even spread between the theoretical and practical aspects of pneumatic conveying technology.
This book constitutes the refereed proceedings of the 6th International Conference on Intelligent Data Engineering and Automated Learning, IDEAL 2005, held in Brisbane, Australia, in July 2005. The 76 revised full papers presented were carefully reviewed and selected from 167 submissions. The papers are organized in topical sections on data mining and knowledge engineering, learning algorithms and systems, bioinformatics, agent technologies, and financial engineering.
This volume deals with substances in the liquid state that range from high melting salts, such as calcium fluoride, through slags, such as silicates, down to lower melting salts, such as lithium nitrate, molten hydrated salts, such as magnesium chloride hexahydrate, to room temperature ionic liquids, such as 1,3-dimethylimmidazolium tetraphenylborate. It provides the reader with annotated, critically examined, and compiled data for such materials. The data includes a variety of thermochemical, structural, and transport properties. The book includes correlations of measured properties; these correlations should enable the reader to estimate, on a sound basis, properties for ionic liquids that have not yet been measured.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.