Jews are a people of law, and law defines who the Jewish people are and what they believe. This anthology engages with the growing complexity of what it is to be Jewish — and, more problematically, what it means to be at once Jewish and participate in secular legal systems as lawyers, judges, legal thinkers, civil rights advocates, and teachers. The essays in this book trace the history and chart the sociology of the Jewish legal profession over time, revealing new stories and dimensions of this significant aspect of the American Jewish experience and at the same time exploring the impact of Jewish lawyers and law firms on American legal practice. “This superb collection reveals what an older focus on assimilation obscured. Jewish lawyers wanted to ‘make it,’ but they also wanted to make law and the legal profession different and better. These fascinating essays show how, despite considerable obstacles, they succeeded.” — Daniel R. Ernst Professor of Law, Georgetown University Law Center Author of Tocqueville’s Nightmare: The Administrative State Emerges in America, 1900-1940 “This fascinating collection of essays by distinguished scholars illuminates the distinctive and intricate relationship between Jews and law. Exploring the various roles of Jewish lawyers in the United States, Germany, and Israel, they reveal how the practice of law has variously expressed, reinforced, or muted Jewish identity as lawyers demonstrated their commitments to the public interest, social justice, Jewish tradition, or personal ambition. Any student of law, lawyers, or Jewish values will be engaged by the questions asked and answered.” — Jerold S. Auerbach Professor Emeritus of History, Wellesley College Author of Unequal Justice and Rabbis and Lawyers
Based on interviews with workers at a chemical factory, this study elicits perceptions of authority relations at work and provides information on the degree to which people see these relations as legitimate. The employees discuss safety, self-fulfillment and resistance to authority.
The last in a series of three volumes edited by Marc Lee Raphael surveying some of the major rabbinic and lay personalities who have shaped Judaism in America for the past two centuries, this work focuses on Orthodox Judaism. Along with a basic description of the achievements of some of the most notable leaders, a bibliography of their writings and sources for further study is included as well as an essay on Orthodox rabbinic organizations and a survey of American Orthodox periodicals. Of interest to scholars, students, and lay persons alike, this volume will inform readers about the earliest communities of Jews who settled in America as they developed the institutions of Orthodox Jewish life and set a public standard of compliance with Jewish law. These early American Jews followed a Spanish-Dutch version of Sephardic customs and rites. Their synagogues used traditional prayer books, promoted the celebration of Jewish holidays, established mikvahs, acquired Passover provisions, and arranged for cemetery land and burial services. While many of these Sephardic immigrants did not maintain halakha in their daily regimen as did their European counterparts, they set a public standard of compliance with Jewish law, thus honoring Jewish tradition. Further immigration of thousands of Jews from Western and Central Europe in the middle of the 19th century brought a world of traditional piety and extensive Jewish learning to America, exemplified by Rabbi Abraham Rice, who served in Baltimore, and Yissachar Dov (Bernard) Illowy, who served communities from Philadelphia to New Orleans. Such men marked the beginning of a learned and scholarly rabbinate in America. This volume provides valuable biographical insights regarding some of the most notable religious leaders in American Orthodoxy.
First the Bad News: Family businesses make up the vast majority of the economy, yet their failure rates are just as high as non-family firms. The tragedy is that when a family business goes under, an entire family’s legacy is lost, often with traumatic consequences. Now for the Good News: Family business suicides CAN be prevented, but not without: 1. Identifying each of the many factors involved 2. Discovering the complexity of the context of your particular situation and 3. Understanding the dynamics of the people involved. Based on well documented and extensive academic research and more than 20 years of practical coaching and mentoring experience, this book will: - Highlight the key differentiators between corporate versus family firm succession processes – so you can better understand the scientifically established principles to improve the chance of success within your family firm. - Help you as the next generation heir ascend to the throne without wreaking havoc within your family – there is no point in saving the business if you destroy your family in the process! - Help guide you if you are a non-family member in a family-run firm – so you won’t feel helpless the next time a family issue spills over into the business. - Give you advice on transferring family ownership to outsiders – even though this might not be your first choice, it might be an unavoidable reality that requires you to be ready to transition properly if you are to maximise your exit strategy. - Help you avoid the most common mistakes and missteps that claim too many family firms. The suggestions and advice are based on cutting edge research combined with practical tips you can apply in your business immediately. The Only Cure for Family Business Suicide is Prevention: Admittedly, the book’s title is provocative. It was chosen in part to get you to pick it up off the bookshelf, but more importantly to bring much needed attention to an increasingly alarming problem - the preventable failure of family businesses. Family dynamics are messy, complex and complicated by the inclusion (and sometimes exclusion) of family members in the business. This book takes a uniquely different approach to reveal a multitude of perspectives to look at the various sources of conflict* involved so they can be identified, isolated and dealt with strategically, diplomatically and effectively. This thoroughly documented expose brings decades of academic research and literature to you, the small family business owner, in a format that is easy to digest with practical recommendations you can implement immediately. Sadly, many family businesses fail, not because their issues were insurmountable, but rather because they were unaware of the most common mistakes and how they could have been easily avoided. In the case of family business "suicide" - the only cure is prevention. This book is the first step in administering the cure, the vaccine against the infection that afflicts too many families and their businesses. * Suggestion from the author: Buy one book for each family member, to avoid conflict… Conflict prevention is the cure remember?
This book provides a holistic and practical approach to Japanese concepts of lean management throughout the business value chain. It explains principles like Kaizen, Kata or Keiretsu in a pragmatic and logical way with many industry examples and case studies. The authors describe comprehensively how lean management enables companies to concentrate on value-adding activities and processes to achieve a long-term, sustainable competitive advantage. Moreover, the book shows how lean management principles are ultimately applied in industries like aviation, civil engineering, automotive, healthcare, education and other industries.
Consistently lauded for its comprehensiveness and full-color color presentation, the latest edition of Rheumatology by Marc C. Hochberg, MD, MPH et al. continues the tradition of excellence of previous editions. Designed to meet the needs of the practicing clinician, it provides extensive, authoritative coverage of rheumatic disease from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format covering all major disorders of the musculoskeletal system in complete, self-contained chapters. Get trusted perspectives and insights from chapters co-authored by internationally renowned leaders in the field, 25% of whom are new to this edition. Track disease progression and treat patients more effectively with the most current information, including 22 new chapters on genetic findings, imaging outcomes, and cell and biologic therapies as well as rheumatoid arthritis and SLE. Incorporate the latest findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics.
Marc Wyse's father wanted him to be a lawyer. His mother wanted him to be a doctor. Instead, he became an advertising executive. In The Way I Saw It, Wyse narrates his rags-to-riches tale of the American dream come true: cofounding Wyse Advertising and working more than sixty years in the business. In this memoir he tells his story of the boy of immigrant parents who grew into an advertising icon that spawned famous theme lines like, With a name like Smucker's, it has to be good, Ask Sherwin-Williams. An advertising legend and consummate salesman, his client list included American Express, Applebee's, BFGoodrich, Clairol, General Dynamics, GE Lighting, Goodyear, Kelly Services, Marathon Oil, New York Yankees, Renaissance Hotels and Resorts, Sherwin-Williams, Smucker's, Stouffer Restaurants Hotels & Resorts, and Timken. The Way I Saw It shares both the life lessons and business lessons learned on the journey to success. Wyse delivers the message: Act like a turtle and never be afraid to stick your neck out.
When American history is divided into discrete eras, the New Deal stands, along with the Civil War, as one of those distinctive events that forever change the trajectory of the nation&’s development. The story of the New Deal provides a convenient tool of periodization and a means of interpreting U.S. history and the significance of contemporary political cleavages. Eisner&’s careful examination of the historical record, however, leads one to the conclusion that there was precious little &“new&” in the New Deal. If one wishes to find an event that was clearly transformative, the author argues, one must go back to World War I. From Warfare State to Welfare State reveals that the federal government lagged far behind the private sector in institutional development in the early twentieth century. In order to cope with the crisis of war, government leaders opted to pursue a path of &“compensatory state-building&” by seeking out alliances with private-sector associations. But these associations pursued their own interests in a way that imposed severe constraints on the government&’s autonomy and effectiveness in dealing with the country&’s problems&—a handicap that accounts for many of the shortcomings of government today.
In Leading the Way, Hewitt Associates’ business leaders Robert Gandossy and Marc Effron present their findings from the largest research project ever conducted on leadership, the "Top Companies for Leaders." Using data from more than 600 companies around the globe and interviews with senior executives at the top companies, they present a compelling business case for investing in growing leaders. Their stories, examples, and tactics provide tangible, practical tools for leaders everywhere.
Joel Polodny offers a sociological examination of how concerns about status affect market competition and shows how anxieties about status influence partner relations, price and perception in the marketplace.
Presents a collection of research in management control and performance measurement. This book offers guidance for both academic researchers and managers as they work toward improving organizations.
Anyone hoping to improve teamwork, performance, and budgeting, training, and evaluation programs in their organization should look no further. Completely revised, Public Productivity Handbook, Second Edition defines the role of leadership, dimensions of employee commitment, and multiple employee-organization based relationships for effective internal and external connections. It's coverage of new and systematic management approaches and well-defined measurement systems provides guidance on correct utilization of human resources that ensure improvements in productivity and performance. The authors discuss such topics as citizen-driven government and performance, public sector values and productivity, privatization, and productivity barriers in the public sector.
War 2.0: Irregular Warfare in the Information Age argues that two intimately connected grassroots trends—the rise of insurgencies and the rise of the web—are putting modern armies under huge pressure to adapt new forms of counterinsurgency to new forms of social war. After the U.S. military—transformed into a lean, lethal, computerized force—faltered in Iraq after 2003, a robust insurgency arose. Counterinsurgency became a social form of war—indeed, the U.S. Army calls it "armed social work"—in which the local population was the center of gravity and public opinion at home the critical vulnerability. War 2.0 traces the contrasting ways in which insurgents and counterinsurgents have adapted irregular conflict to novel media platforms. It examines the public affairs policies of the U.S. land forces, the British Army, and the Israel Defense Forces. Then, it compares the media-related counterinsurgency methods of these conventional armies with the methods devised by their irregular adversaries, showing how such organizations as al-Qaeda, the Taliban, and Hezbollah use the web, not merely to advertise their political agenda and influence public opinion, but to mobilize a following and put violent ideas into action.
This book brings together emerging perspectives from organization theory and management, environmental sociology, international regime studies, and the social studies of science and technology to provide a starting point for discipline-based studies of environmental policy and corporate environmental behavior. Reflecting the book’s theoretical and empirical focus, the audience is two-fold: organizational scholars working within the institutional tradition, and environmental scholars interested in management and policy. Together this mix forms a creative synthesis for both sets of readers, analyzing how environmental policy and organizational practices are shaped, spread and contested.
Black Power, Jewish Politics expands with this revised edition that includes the controversial new preface, an additional chapter connecting the book's themes to the national reckoning on race, and a foreword by Jews of Color Initiative founder Ilana Kaufman that all reflect on Blacks, Jews, race, white supremacy, and the civil rights movement"--
Lonely Planet: The world's number one travel guide publisher* Lonely Planet's Germany is your passport to the most relevant, up-to-date advice on what to see and skip, and what hidden discoveries await you. Explore the glamour and grit of Berlin, tour hilltop castles in the fairy tale Black Forest and sail along the romantic Rhine - all with your trusted travel companion. Get to the heart of Germany and begin your journey now! Inside Lonely Planet's Germany: Colour maps and images throughout Highlights and itineraries help you tailor your trip to your personal needs and interests Insider tips to save time and money and get around like a local, avoiding crowds and trouble spots Essential info at your fingertips - hours of operation, phone numbers, websites, transit tips, prices Honest reviews for all budgets - eating, sleeping, sightseeing, going out, shopping, hidden gems that most guidebooks miss Cultural insights provide a richer, more rewarding travel experience - history, people, music, landscapes, wildlife, cuisine, politics Covers Berlin and around, Saxony, Munich and Bavaria, Stuttgart and the Black Forest, Frankfurt, Cologne, the Rhineland, Lower Saxony and Bremen, Hamburg and the North, Central Germany and more The Perfect Choice: Lonely Planet's Germany is our most comprehensive guide to Germany, and is perfect for discovering both popular and offbeat experiences. Looking for more extensive coverage? Check out Lonely Planet's Berlin for an in-depth look at all the capital has to offer, or our Munich, Bavaria & the Black Forest regional guide. About Lonely Planet: Lonely Planet is a leading travel media company and the world's number one travel guidebook brand, providing both inspiring and trustworthy information for every kind of traveller since 1973. Over the past four decades, we've printed over 145 million guidebooks and grown a dedicated, passionate global community of travellers. You'll also find our content online, and in mobile apps, video, 14 languages, nine international magazines, armchair and lifestyle books, ebooks, and more. 'Lonely Planet guides are, quite simply, like no other.' - New York Times 'Lonely Planet. It's on everyone's bookshelves, it's in every traveller's hands. It's on mobile phones. It's on the Internet. It's everywhere, and it's telling entire generations of people how to travel the world.' - Fairfax Media (Australia) *Source: Nielsen BookScan: Australia, UK, USA, 5/2016-4/2017 eBook Features: (Best viewed on tablet devices and smartphones) Downloadable PDF and offline maps prevent roaming and data charges Effortlessly navigate and jump between maps and reviews Add notes to personalise your guidebook experience Seamlessly flip between pages Bookmarks and speedy search capabilities get you to key pages in a flash Embedded links to recommendations' websites Zoom-in maps and images Inbuilt dictionary for quick referencing Important Notice: The digital edition of this book may not contain all of the images found in the physical edition.
A scholar examines 14 everyday objects featured in horror films and how they manifest their power and speak to society’s fears. Take a tour of the house where a microwave killed a gremlin, a typewriter made Jack a dull boy, a sewing machine fashioned Carrie’s prom dress, and houseplants might kill you while you sleep. In Household Horror, Marc Olivier highlights the wonder, fear, and terrifying dimension of objects in horror cinema. Inspired by object-oriented ontology and the nonhuman turn in philosophy, Olivier places objects in film on par with humans, arguing, for example, that a sleeper sofa is as much the star of Sisters as Margot Kidder, that The Exorcist is about a possessed bed, and that Rosemary’s Baby is a conflict between herbal shakes and prenatal vitamins. Household Horror reinvigorates horror film criticism by investigating the unfathomable being of objects as seemingly benign as remotes, radiators, refrigerators, and dining tables. Olivier questions what Hitchcock’s Psycho tells us about shower curtains. What can we learn from Freddie Krueger’s greatest accomplice, the mattress? Room by room, Olivier considers the dark side of fourteen household objects to demonstrate how the objects in these films manifest their own power and connect with specific cultural fears and concerns. “Provides a lively and highly original contribution to horror studies. As a work on cinema, it introduces the reader to films that may be less well-known to casual fans and scholars; more conspicuously, it returns to horror staples, gleefully reanimating works that one might otherwise assume had been critically “done to death” (Psycho, The Exorcist, The Shining).” —Allan Cameron, University of Auckland
The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 3 is devoted to the set of mediators of the cell surface, especially ion and molecular carriers and catalytic receptors that, once liganded and activated, initiate signal transduction pathways. Intracellular cascades of chemical reactions trigger the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Primary mediators are included in models of regulated cellular processes, but multiple secondary signaling components are discarded to allow simple, representative modeling and to manage their inverse problems.
Professor Lienhard deals here primarily with the first half of the 16th century, a momentous period which saw the rise and first triumphs of evangelical Christianity. His focus is upon the town of Strasbourg, one of the places where the Reformation first left its mark, and the articles combine to present an illuminating picture of the town's social and religious evolution over the period. Some approach the subject at an individual level, with studies of the protagonists in the events - such as Martin Bucer, Matthieu Zell or Thomas Murner - and their differing religious viewpoints. Other articles take a broader perspective, analysing the social and political background to the triumph of the Reform, the gradual emergence of a new order, and local attitudes towards the new dissidents, the Anabaptists. An important section of additional notes and comments completes the volume. Le Professeur Lienhard s’attache ici, avant tout, à la premiere motié du XVIe siècles, période capitale, qui vit la montée et les premiers triomphes du christianisme évangélique. Il se concentre sur Strasbourg, un des lieux où la Réforme laissa très tôt sa marque. L’ensemble des articles présente une image clarifante de l’évolution sociale et religieuse de la ville durant cette période. Certains abordent le sujet au travers de l’étude de plusiers des protagonistes aillant pris part aux événements - tels que Martin Bucer, Matthieu Zell ou Thomas Murner - et examinent aussi leurs différents points de vue religieux. D’autres prennent une perspective plus large, analysant le contexte politique et social à la base de triomphe de la Réforme et de la naissance d’un ordre nouveau, ainsi que les prises de position locales envers les nouveaux dissidents, les Anabaptistes. Dès a present, ce recueil est accompagné d’une importante section de notes adittionnelles et de commentaires.
Leadership and organisational structures which are not adjusted to the cultural background of the employees concerned are most likely to produce sub-optimal results (House, 2004). Therefore it is necessary to develop appropriate leadership and organisational structures in order to fully grasp the cultural environment to be encountered in the professional world. This book presents a research project that was carried out to develop leadership and organisational structures in accordance with the requirements created by different professional backgrounds within the aviation industry. The identification of the different professional cultures was undertaken using a standardised questionnaire. The development of the questionnaire was carried out with the help of the GLOBE study (House, et al., 2004), one of the most extensive research efforts ever undertaken in the field of organisational and national cultures. The main characteristic of the GLOBE study is the development of nine dimensions which serve to identify and characterise any culture. These dimensions are referred to as 'core cultural dimensions'. Using this newly developed questionnaire, it was not only possible to isolate 12 different professional cultures, but also to identify their distinguishing traits which served as the base for the subsequent development of leadership and organisational structures. The survey was complemented by open interviews served to broaden and deepen the results gained with the standardised questionnaire. The research outcomes open the door to a new and important element of cultural research, complementary to those of organisational and national cultures. Although the study was carried out in the aviation industry, the results gained also appear to be transferable to other industries due to the large variety of professions isolated within the course of the presented study and the specific nature of the aviation industry itself.
Marc Grünhagen examines the evolution of fund-raising struggles in eleven in-depth case studies of seed and early stage ventures. The findings suggest two core recommendations for supporting growth-oriented fund-raising processes: a) to build legitimizing potential and b) to ensure sufficient financial scope for flexible adaptations throughout the financing struggle.
This title was first published in 1980. One of the most prevalent and significant issues facing socialist countries is the role of intellectuals. In the poorer countries like China, this has presented itself with particular acuity in the relationship of scientists and technicians to the process of socialist economic modernization. Since the Cultural Revolution has come to a close, its impact on China’s intellectual life— especially on scientists, technicians, and the development of scientific and technical work— has been the subject of lively inquiry in China. In turn, this inquiry has provided a major focus for reevaluating the Cultural Revolution as a political movement and as a way of dealing with the inequalities and bureaucratic inefficiencies that have arisen and will continue to arise in the centrally planned Chinese economy during a period when rapid economic growth and modernization have been given the highest priority. This monograph intends to address some of these issues by presenting a detailed case study of a Chinese technical unit over the period from 1966 to 1974.
Under Construction offers a unique examination of organization and work in the construction industry. Synthesizing organizational and labor relations orientations, it develops a comprehensive sociological perspective on work relations in construction. Silver examines the effects of local market conditions, employers' demands, and trade union activities on the daily lives of workers—skilled as well as unskilled. The book also challenges popular myths about construction work and the building trades with analyses of construction sites, hiring practices, and workers' reactions to the conditions of their work. Under Construction powerfully demonstrates the need for new industrial approaches by concluding with a series of practical alternatives to current practices in the industry's housing sector.
Does the political thinking of ordinary citizens change during periods of crisis? Marc Lendler addresses this question by investigating the story behind an unusually prolonged and ultimately successful strike - a five-year conflict at the Colt Firearms Company in Hartford, Connecticut, in the 1980s. Lendler documents how the participants' political consciousness evolved during this period, showing what they thought about American politics and institutions.
Together, the volumes in this series present all of the data needed at various length scales for a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to, and remove carbon dioxide from, the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanism. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems, together with the mathematical tools to describe their functioning in quantitative terms. The present volume focuses on macroscopic aspects of the cardiovascular and respiratory systems in normal conditions, i.e., anatomy and physiology, as well as the acquisition and processing of medical images and physiological signals.
While political history has plenty to say about the impact of Ronald Reagan’s election to the presidency in 1980, four Senate races that same year have garnered far less attention—despite their similarly profound political effect. Tuesday Night Massacre looks at those races. In examining the defeat in 1980 of Idaho’s Frank Church, South Dakota’s George McGovern, John Culver of Iowa, and Birch Bayh of Indiana, Marc C. Johnson tells the story of the beginnings of the divisive partisanship that has become a constant feature of American politics. The turnover of these seats not only allowed Republicans to gain control of the Senate for the first time since 1954 but also fundamentally altered the conduct of American politics. The incumbents were politicians of national reputation who often worked with members of the other party to accomplish significant legislative objectives—but they were, Johnson suggests, unprepared and ill-equipped to counter nakedly negative emotional appeals to the “politically passive voter.” Such was the campaign of the National Conservative Political Action Committee (NCPAC), the organization founded by several young conservative political activists who targeted these four senators for defeat. Johnson describes how such groups, amassing a great amount of money, could make outrageous and devastating claims about incumbents—“baby killers” who were “soft on communism,” for example—on behalf of a candidate who remained above the fray. Among the key players in this sordid drama are NCPAC chairman Terry Dolan; Washington lobbyist Charles Black, a top GOP advisor to several presidential campaigns and one-time business partner of Paul Manafort; and Roger Stone, self-described “dirty trickster” for Richard Nixon and confidant of Donald Trump. Connecting the dots between the Goldwater era of the 1960s and the ascent of Trump, Tuesday Night Massacre charts the radicalization of the Republican Party and the rise of the independent expenditure campaign, with its divisive, negative techniques, a change that has deeply—and perhaps permanently—warped the culture of bipartisanship that once prevailed in American politics.
An authoritative medical reference on the various ways in which Long-COVID presents and an in-depth discussion of its mechanisms and therapeutic options. Unravelling Long-COVID aims to provide a better awareness and understanding of the persistent health problems that can arise following SARS-CoV-2 infection. Variously described as Long-COVID, Long-Haulers’ Syndrome, and Post-Acute Sequelae of SARS-CoV-2, this newly-designated disorder is estimated to have affected somewhere between 50 to 250 million people. It is in fact considered by many as the next global public health disaster. With such a broad and important topic, the authors of Unravelling Long-COVID have focused primarily on two major problems in the current understanding of Long-COVID: 1.) the failure to distinguish patients with organ damage—here called Long-COVID Disease – and those with unexplained, persistent symptoms—what is termed Long-COVID syndrome, 2.) and the failure of current medical approaches to comprehend and treat those persistent unexplained symptoms Unravelling Long-COVID is: One of the first books focused specifically on defining and understanding Long-COVID with the goal of establishing optimal management A unique reference to distinguish patients with organ damage caused by Long-COVID disease from those with unexplained, persistent symptoms that manifest as Long-COVID syndrome An in-depth exploration of neuroimmune pathways to help clarify the previously unexplained symptoms of Long-COVID Unravelling Long-COVID isan essential reference for anyone interested in Long-COVID and the impact that this condition has had on the population. It will be a useful resource for the growing number of Long-COVID clinics that have been established across the US, the UK, and other countries. This book will be paired with a long-COVID website, updated regularly by the authors, so the reader will be kept up to date with new clinical and research findings.
Structure of Antigens discusses a variety of topics dealing with the structural basis of antigenicity. Topics include the analytical methods used to elucidate the structure of antigens, the structure of antibodies, the principles underlying modern immunoassays and the measurement of antibody binding affinity, and physicochemical principles and methodological aspects. The book also considers major groups of antigens distinguished by their functional activity and biological role (e.g., drugs, autoantigens, snake toxins, allergens) or by their association with particular biological systems (e.g., antigens of microorganisms). Structure of Antigens will provide a current, useful, reference for researchers and graduate students in all fields of biological science who need an overview of antigenic specificity. VOLUME II
Many elderly patients suffer from psychiatric conditions that result from--or are made worse by--existing medical conditions. This new edition integrates clinical expertise needed to evaluate and treat psychiatric, medical and neurologic disorders in the older patient. Both scientific foundations of and clinical approaches to psychiatric disease are discussed by a range of experts who rely on evidence-based clinical guidelines and outcomes data. Most chapters include case studies that illuminate the approaches to diagnosis and treatment. The book's five sections include basic principles of evaluation and treatment for specific disorders; appendices offer further insight into pharmacotherapy and neuroanatomic foundation of psychiatric diseases.
Most complex biological systems, such as enzyme pathways, are effec tively controlled near the beginning of the process. There is increasing evidence that the same is true for the immune system, with the initial interactions between antigen, antigen-presenting cells, and T cells hav ing a paramount influence on the ensuing events. Thus, analysis of the early stages of the immune responses has been a preoccupation of many immunologists. This has been considerably aided by the capac ity to expand these early events, and 'immortalize' them as clones of T cells, for detailed analysis. The discovery by Morgan, Ruscetti, and Gallo (Science 193, 1007, 1976) of T-cell growth factor (now termed interleukin-2 or IL-2) has had a major impact in immunology that is far from over. The greater ease of handling murine tissues experimentally, with the availability of more precisely defined reagents such as inbred strains, has meant that, to date, most of the work on long-term T-cell cultures has been per formed in the mouse, as summarized by Fathman and Fitch (eds. , Iso lation, Characterization and Utilization of T Lymphocyte Clones, Aca demic Press, NY, 1982). However, the limitations of working with human tissues are counterbalanced by the great long-term importance of understanding disorders of human immune regulation, especially since it is becoming evident that these are far from rare. Immune deficiencies such as agammaglobulinemia and T-cell deficiencies are not common, but immune hyperresponsiveness occurring in allergy and allergiC diseases (e. g.
What happens to intergovernmental organizations (IGOs) after their creation has remained in mystery over the years. Although the current globalized outlook has sparked new and growing interests on the role that IGOs play in the global landscape, the scholarship has largely focused on the political aspects of cooperation, primarily on how and why different IGO member states interact with each other and the outcomes associated with such cooperation. Research is yet to untangle how these organizations work and operate. This Element addresses this niche in the literature by delving into two important aspects: the management and governance of IGOs. We build on a four-year research program where we have collected three types of different data and produced several papers. Ultimately, the Element seeks to provide scholars with a description of the inner workings of IGOs, while providing guidance to policymakers on how to manage and govern them.
The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major sets of intracellular mediators that transmit signals upon stimulation of cell-surface receptors. Activation of signaling effectors triggers the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Complex stages of cell signaling can be studied using proper mathematical models, once the role of each component is carefully handled. Volume 4 also reviews various categories of cytosolic and/or nuclear mediators and illustrates some major signal transduction pathways, such as NFkappaB axis, oxygen sensing, and mechanotransduction.
Increasing Project Flexibility: The Response Capacity of Complex Projects fills this void as a report of research conducted by Serghei Floricel, Sorin Piperca, and Marc Banik. Project organizations generate a social structure that is unique to each organization. One of the essential properties of the structure is its ability to deal with unexpected events, or what the authors call its “response capacity.” To explore and better understand this element, the authors adopt a three-stage approach that includes theoretical development, qualitative investigation, and quantitative exploration. In the theoretical development stage, the study draws on fundamental social theories and prior project management research to propose three properties of the project structure that define its response capacity: cohesion, flexibility, and resourcefulness.
This volume includes perspectives on public service selected from six decades of major public administration journals. Recurring themes include: motivations to enter the public service, positive and negative images of public servants and of government, conflicts between loyalty to the organization and loyalty to the public, morale, burnout, and turnover. The volume also includes cross-national analyses of the public service in other systems, proposals for rethinking public service systems, and questions as to the future of the public service. It recaptures a long, continuing debate as to the health of the public service, and in so doing suggests agendas for university research and administrative action.
Explains what the law is on common religious liberty and church-state questions in the public school context. Covers: prayer in the schools; teaching about religion; use of classroom space for student-initiated religious activities; holiday observances; released time programs; physical facilities; dual enrollment; distribution of Gideon bibles or religious literature; scientific creationism; curriculum content; secular humanism; compulsory attendance and religious holidays; dress codes; vaccination requirements; and teachers' rights and responsibilities.
First published in 1986 under the editorial direction of Dr. Henry J.M. Barnett, Stroke: Pathophysiology, Diagnosis, and Management continues to provide the dependable, current answers you need to effectively combat the increasing incidence of this disease. Dr. J.P. Mohr, together with new associate editors Philip A. Wolf, James C. Grotta, Michael A. Moskowitz, Marc Mayberg, and Rüdiger von Kummer as well as a multitude of expert contributors from around the world, offer you updated and expanded coverage of mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more, equipping you to understand the latest scientific discoveries and make effective use of the newest approaches to diagnosis and treatment. Gain fresh perspectives and up-to-date insights from the world’s leading authorities on the pathophysiology, diagnosis, and management of stroke. Access the comprehensive, expert clinical guidance you need to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Make efficient and accurate diagnoses with the aid of abundant full-color CT images and pathology slides. Stay up to date on hot topics such as mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more.
This valuable reference provides a wide range of practical, clinical information for physicians who care for patients with neurological and cardiac problems. Clinical Neurocardiology considers neurological complications arising from cardiac surgery and other cardiac interventions describes neurological findings in heart dise
The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Volume 5 is devoted to cells, tissues, and organs of the cardiovascular and ventilatory systems with an emphasis on mechanotransduction-based regulation of flow. The blood vessel wall is a living tissue that quickly reacts to loads applied on it by the flowing blood. In any segment of a blood vessel, the endothelial and smooth muscle cells can sense unusual time variations in small-magnitude wall shear stress and large-amplitude wall stretch generated by abnormal hemodynamic stresses. These cells respond with a short-time scale (from seconds to hours) to adapt the vessel caliber. Since such adaptive cell activities can be described using mathematical models, a key objective of this volume is to identify the mesoscopic agents and nanoscopic mediators required to derive adequate mathematical models. The resulting biomathematical models and corresponding simulation software can be incorporated into platforms developed in virtual physiology for improved understanding and training.
Providing a much-needed critique of Corporate Social Responsibility (CSR) practice and scholarship, this book seeks to redress CSR advocacy, from a political and critical perspective. A strident approach backed up by extensive use of case studies presents the argument that most CSR-related activity aims to gain legitimacy from consumers and employees, and therefore furthers the exploitative and colonizing agenda of the corporation. By examining CSR in the context of the political economy of late capitalism, the book puts the emphasis back on the fact that most large corporations are fundamentally driven by profit maximization, making CSR initiatives merely another means to this end. Rather than undermining or challenging unsustainable corporate practices CSR is exposed as an ideological practice that actually upholds the prominence of such practices. As CSR gathers momentum in management practice and scholarship, students in the fields of CSR, business ethics, and strategy, will find this text a useful companion to counter received wisdom in this area.
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