Marc Harrold's Books

Basic Concepts in Medicinal Chemistry

By: Marc Harrold,Robin Zavod

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Basic Concepts in Medicinal Chemistry

By: Marc Harrold,Robin Zavod

Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.

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405

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ASHP

Published Date

ISBN 10

1585283649

ISBN 13

9781585283644

Medicinal Chemistry Self Assessment

By: Robin Zavod,Marc Harrold

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Medicinal Chemistry Self Assessment

By: Robin Zavod,Marc Harrold

Medicinal Chemistry has always been a tough course, a source of frustration in every school of pharmacy. Now ASHP has made both learning and teaching it much easier and more effective, with the publication of Medical Chemistry Self Assessment. Developed by Robin M. Zavod and Marc W. Harrold, authors of the highly praised textbook, Basic Concepts in Medicinal Chemistry, this Self Assessment is the only publication of its kind. A highly engaging way for pharmacy and pre-health students to master the complexities of medicinal chemistry, it reinforces what they learn in class with practice problems and review questions which are answered at the end of the book. The Self Assessment book and its related online content are also handy teaching tools, as well as a source of new problem formats and strategies for exploring concepts from different perspectives. Zavod and Harrold’s approach provides a clear translation of organic chemistry concepts into medicinal chemistry language, and includes numerous clinically relevant examples, relating medicinal chemistry to therapeutic decisions. A valuable enhancement to any medicinal chemistry text, this book will also be very helpful for students learning organic or biochemistry, as well as for practitioners who want to renew their understanding of medicinal chemistry.

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324

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ASHP

Published Date

ISBN 10

1585284661

ISBN 13

9781585284665

Steve McQueen

A Biography

By: Marc Eliot

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Steve McQueen

A Biography

By: Marc Eliot

Steve McQueen is one of America's legendary movie stars best known for his hugely successful film career in classics such as The Magnificent Seven, The Great Escape, The Thomas Crown Affair, Bullitt, and The Towering Inferno as well as for his turbulent life off-screen and impeccable style. His unforgettable physical beauty, his soft-spoken manner, his tough but tender roughness, and his aching vulnerability had women swooning and men wanting to be just like him. Today--nearly thirty years after he lost his battle against cancer at the age of fifty--McQueen remains "The King of Cool." Yet, few know the truth of what bubbled beneath his composed exterior and shaped his career, his passions, and his private life. Now, in Steve McQueen, New York Times bestselling author, acclaimed biographer, and film historian, Marc Eliot captures the complexity of this Hollywood screen legend. Chronicling McQueen's tumultuous life both on and off the screen, from his hardscrabble childhood to his rise to Hollywood superstar status, to his struggles with alcohol and drugs and his fervor for racing fast cars and motorcycles, Eliot discloses intimate details of McQueen's three marriages, including his tumultuous relationships with Neile Adams and Ali MacGraw, as well as his numerous affairs. He also paints a full portrait of this incredible yet often perplexing career that ranged from great films to embarrassing misfires. Steve McQueen, adored by millions, was obsessed by Paul Newman, and it is the nature of that obsession that reveals so much about who McQueen really was. Perhaps his greatest talent was to be able to convince audiences that he was who he really wasn't, even as he tried to prove to himself that he wasn't who he really was. With original material, rare photos, and new interviews, Eliot presents a fascinating and complete picture of McQueen's life.

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370

Publisher

Random House Digital, Inc.

Published Date

ISBN 10

0307453219

ISBN 13

9780307453211

Diseases of the Breast

By: Jay R. Harris,Marc E. Lippman,C. Kent Osborne,Monica Morrow

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Diseases of the Breast

By: Jay R. Harris,Marc E. Lippman,C. Kent Osborne,Monica Morrow

Completely revised and updated, and now in full color throughout, the Fourth Edition of this definitive reference is a must for all clinicians who treat breast diseases. Leading experts summarize the current knowledge of breast diseases, including their clinical features, management, underlying biologies, and epidemiologies. In addition to complete coverage of malignant breast diseases, benign diseases are discussed in relation to subsequent breast cancer development. The book reviews all major clinical trials and summarizes the information they provide on early detection and management of breast cancer. Close attention is also given to the increasing importance of molecular biology and genetics in this field. This edition features more than thirty new contributors, fourteen new or completely rewritten chapters, and more clinically oriented chapters. A companion Website will offer the fully searchable text and an image bank. Also included with this edition is the Anatomical Chart Company's Breast Anatomy and Disorders Pocket Guide. This durable, portable folding pocket guide provides a visual and textual overview of breast anatomy, disorders, and breast self-examination. With a write-on, wipe-off laminated surface, this guide is perfect for the on-the-go practitioner to show patients, caregivers, and families.

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3432

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1451148704

ISBN 13

9781451148701

Early Beverly Hills

By: Marc Wanamaker

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Early Beverly Hills

By: Marc Wanamaker

Way before Rodeo Drive and the pink palace of the Beverly Hills Hotel were built, way before the namesake hillbillies, its zip code, and Eddie Murphys detective techniques reaffirmed its place in popular culture, and way before its 1,001 mansions, Beverly Hills was comprised of wild canyons and ranchlands. Burton Green, one of the three original land developers of the Rancho Rodeo de las Aguas, named this place of severe terrain after Beverly Farms, Massachusetts, a 19th-century spa. Since its establishment in 1907, Beverly Hills, California, has been a crossroads for the great movers and shakers of the entertainment industry as well as the tycoons, world leaders, and flotsam and jetsam magnetized by the limelight. The vintage photographs in this provocative volume illustrate Beverly Hillss early transition from cow pastures to Hollywoods extremely illustrious bedroom community.

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132

Publisher

Arcadia Publishing

Published Date

ISBN 10

1439614482

ISBN 13

9781439614488

Kick Off League 1&2 2005-06

By: Marc Fiszman,Mark Peters

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Kick Off League 1&2 2005-06

By: Marc Fiszman,Mark Peters

A definitive guide to the Premiership, featuring an entry for each club highlighting the players and statistics, together with the enhanced fixture list, maps and directions to the grounds of all the clubs in the Premiership.

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115

Publisher

Sidan Press

Published Date

ISBN 10

1903073332

ISBN 13

9781903073339

Advances in Geosciences

By: Marc Duldig

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Advances in Geosciences

By: Marc Duldig

Advances in Geosciences is the result of a concerted effort to bring together the latest results and planning activities related to earth and space science in Asia and the international arena. The volume editors are all leading scientists in their research fields covering six sections: Atmospheric Science (AS), Hydrological Science (HS), Ocean Science (OS), Solid Earth (SE), Solar Terrestrial (ST) and Planetary Science (PS). The main purpose is to highlight the scientific issues essential to the study of earthquakes, tsunamis, atmospheric dust storms, climate change, drought, flood, typhoons, monsoons, space weather, and planetary exploration. This volume is abstracted in NASA''s Astrophysics Data System: http: //ads.harvard.edu. Sample Chapter(s). Chapter 1: Ulf Waves: Exploring the Earth''s Magnetosphere (1,240k). Contents: ULF Waves: Exploring the Earth''s Magnetosphere (B J Fraser); Spectrum of Density Fluctuations in the Solar Wind (V Krishnan); Polarization Properties of the Ultra-Low Frequency Waves in Non-Axisymmetric Background Magnetic Fields (K Kabin et al.); and other papers. Readership: Academics, researchers and postgraduate students in geosciences

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332

Publisher

World Scientific

Published Date

ISBN 10

9812836209

ISBN 13

9789812836205

Fundamentals of Cognition

By: Michael W. Eysenck,Marc Brysbaert

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Fundamentals of Cognition

By: Michael W. Eysenck,Marc Brysbaert

Is it possible to learn something without being aware of it? How does emotion influence the way we think? How can we improve our memory? Fundamentals of Cognition, third edition, provides a basic, reader-friendly introduction to the key cognitive processes we use to interact successfully with the world around us. Our abilities in attention, perception, learning, memory, language, problem solving, thinking, and reasoning are all vitally important in enabling us to cope with everyday life. Understanding these processes through the study of cognitive psychology is essential for understanding human behaviour. This edition has been thoroughly updated and revised with an emphasis on making it even more accessible to introductory-level students. Bringing on board Professor Marc Brysbaert, a world-leading researcher in the psychology of language, as co-author, this new edition includes: developed and extended research activities and "In the Real World" case studies to make it easy for students to engage with the material; new real-world topics such as discussions of attention-deficit/hyperactivity disorder, the reading problems of individuals with dyslexia, why magic tricks work, and why we cannot remember the Apple logo accurately; a supporting companion website containing multiple choice questions, flashcards, sample essay answers, instructor resources, and more. The book provides a perfect balance between traditional approaches to cognition and cutting-edge cognitive neuroscience and cognitive neuropsychology. Covering all the key topics within cognition, this comprehensive overview is essential reading for all students of cognitive psychology and related areas such as clinical psychology.

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768

Publisher

Routledge

Published Date

ISBN 10

1317208536

ISBN 13

9781317208532

Paramount Studios

1940-2000

By: Marc Wanamaker,Michael Christaldi,E.J. Stephens

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Paramount Studios

1940-2000

By: Marc Wanamaker,Michael Christaldi,E.J. Stephens

The fascinating tale of Hollywood powerhouse Paramount Pictures--beginning with its birth in the 1910s through the turbulent decade of the 1930s--was told in Early Paramount Studios by Marc Wanamaker, Michael Christaldi, and E.J. Stephens. Now the same authors are back to tell the next 60 years of the studio saga in Paramount Studios: 1940-2000, with a foreword by former Paramount head of production Robert Evans. This book picks up the story during the time of World War II--a successful era for the studio--which was followed by a decade of decline due to the upstart medium of television. By the 1960s, the studio teetered on the brink of bankruptcy before rebounding, thanks to several 1970s blockbusters, such as Love Story, The Godfather, and Chinatown. The tale continues through the final decades of the 20th century when Paramount showcased some of the greatest hits in its history.

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128

Publisher

Arcadia Publishing

Published Date

ISBN 10

1439655286

ISBN 13

9781439655283

Franklin Richards

A Fantastic Year

By: Chris Eliopoulos,Marc Sumerak

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Franklin Richards

A Fantastic Year

By: Chris Eliopoulos,Marc Sumerak

Collecting Material From Franklin Richards: Son Of A Genius, Everybody Loves Franklin, Spring Break, March Madness!, April Fools!, Sons Of Geniuses, Schools Out!, Super Summer Spectacular, Fall Football Fiasco!, Dark Reigning Cats And Dogs And Happy Franksgiving! A birthday surprise from his future self kicks off an eventful year for the son of a genius! With best pal H.E.R.B.I.E. by his side, Franklin Richards loves making mischief with his Fantastic fathers inventions but can any of them make school go by faster? Katie Power wants to be Franklins Valentine as he navigates a basketball brouhaha and an April Fools fiasco! But will Franklins nemesis Kristoff ruin his summer fun in the sun? As baseball season gives way to football fever, Franklin has tricks and treats planned for Halloween but hell soon find interdimensional turkey trouble and a Christmas time warp!

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109

Publisher

Marvel Entertainment

Published Date

ISBN 10

1302505971

ISBN 13

9781302505974

Time Enought

Fiction Short Stories

By: Marc Neuffer

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Time Enought

Fiction Short Stories

By: Marc Neuffer

28 stories of strange people, places and times. To survive, always have an exit... two is better. These stories encompass far-flung space flight, dystopian situations, Artificial Intelligence, aliens with twisted endings and deception.... all for your enjoyment. The first story starts with a young woman racing to save her life in a long-buried survival enclave. From there we join an interstellar trader who has a strange cargo forced on her. Other stories pose questions such as can you steal a planet, what will world leaders do when faced with an alien invasion is only 20 years away...The last stories two are of a different color, the fist a twisted reality and the second a more contemporary trial of personal struggle to make sense of what needs to be done when faced with tragedy.

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204

Publisher

Marc Neuffer

Published Date

ISBN 13

9798410887564

Beverly Hills

1930-2005

By: Marc Wanamaker

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Beverly Hills

1930-2005

By: Marc Wanamaker

Nowhere on Earth are sequels and the success that fosters them more apparent than in Hollywood's bejeweled bedroom, Beverly Hills. This continuation of the history begun in Arcadia Publishing's Images of America: Early Beverly Hills presents a compendium of vintage photographs depicting America's one community that's most synonymous with wealth. However, the Great Depression hit here, too, and the book depicts that as well as the subsequent recovery and boom years, homes of the stars, influence of the close proximity to Hollywood, and the chic shops and restaurants that keep the tourists coming. From the Brown Derby to the Beverly Theatre, from the Harold Lloyd Estate to Jack Warner's digs, from the Beverly Hills Hotel's changes to those that created a new Beverly Hills Civic Center, these are the Beverly Hills facts that have been the bases for all of those Hollywood fictions.

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201

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Arcadia Publishing

Published Date

ISBN 10

1439618151

ISBN 13

9781439618158

Herbs and Natural Supplements, Volume 2

An Evidence-Based Guide

By: Lesley Braun,Marc Cohen

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Herbs and Natural Supplements, Volume 2

An Evidence-Based Guide

By: Lesley Braun,Marc Cohen

Herbs and Natural Supplements, 4th Edition: An evidence-based guide is an authoritative, evidence-based reference. This two-volume resource is essential to the safe and effective use of herbal, nutritional and food supplements. The second volume provides current, evidence-based monographs on the 132 most popular herbs, nutrients and food supplements. Organised alphabetically, each monograph includes daily intake, main actions and indications, adverse reactions, contraindications and precautions, safety in pregnancy and more. - Recommended by the Pharmacy Board of Australia as an evidence-based reference works (print) that pharmacists are meant to have access to when dispensing - Contributed content from naturopaths, GPs, pharmacists, and herbalists - Useful in a clinical setting as well as a reference book. - It provides up-to-date evidence on the latest research impacting on herbal and natural medicine by top leaders in Australia within the fields of Pharmacy, Herbal Medicine and Natural Medicine

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1379

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

072958173X

ISBN 13

9780729581738

The Discretionary Economy

A Normative Theory of Political Economy

By: Marc Tool

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The Discretionary Economy

A Normative Theory of Political Economy

By: Marc Tool

The Discretionary Economy argues that we do in fact control our own political and economic destinies. As a community, we have discretion over policies that determine whether an economic process adequately provides for the necessities of life. We also determine who participates in normative public judgments and whether decisions distinguish between what is and what ought to be. Tool argues that we must continuously organize the institutional structures through which economic and political functions in the social process are carried on. We must exercise discretion by creating and modifying institutions that coordinate our behavior. To exercise discretion effectively requires that we employ distinctively American economic, political, and philosophical theory. In this volume, the pivotal twentieth-century contributors to this encompassing theory of political economy are Thorstein Veblen, John Dewey, Clarence Ayres, and R. Fagg Foster. This volume presents, in detail, their analytical and philosophical perspective on social change. A major purpose of this volume is to compare and contrast the American tradition with the traditions of capitalism, Marxism, and fascism, demonstrating that the former can resolve compelling economic and political problems and the latter two cannot. This book explains how to identify and analyze social, economic, and political problems confronted in all communities, and how to go about framing and implementing structural adjustments in the political economy. It will be of interest to students in non-traditional courses in political economy including institutional economics, contemporary social problems, economics and social policy, methodology, and contemporary economic thought.

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Page Count

350

Publisher

Routledge

Published Date

ISBN 10

1351304860

ISBN 13

9781351304863

Doctor Strange

What is it that Disturbs You, Stephen?

By: Marc Andreyko

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Doctor Strange

What is it that Disturbs You, Stephen?

By: Marc Andreyko

Collects Dr. Strange: What Is It That Disturbs You, Stephen? #1; Dr. Strange Annual #1; Marvel Premiere #7; Doctor Strange (1974) #34 and material from Doctor Strange (1974) #46; Marvel Fanfare (1982) #5, 6, 8; Chamber of Chills #1-2; Journey Into Mystery (1972) #4.ÿ Magical tales from a spellbinding artist! P. Craig Russell brings his distinctive style to Doctor Strange in an Eisner Award-winning tale decades in the making. Its a psychedelic story of sorcerous seduction that will take you from the arcane shadows of the Sanctum Sanctorum to the dizzying spires of the mystical city of Ditkopolis! The Master of the Mystic Arts puts Clea to the test, faces a challenge to his title as Sorcerer Supreme and battles a hoary host of foes. Plus: Russell turns his attention to (Scarlet) witchcraft and other chilling mysteries!

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Page Count

229

Publisher

Marvel Entertainment

Published Date

ISBN 10

1302493795

ISBN 13

9781302493790

Ororo

Before The Storm

By: Marc Sumerak

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Ororo

Before The Storm

By: Marc Sumerak

Collects Ororo: Before the Storm (2005) #1-4, Uncanny Origins (1996) #9, Uncanny X-Men: First Class (2009) #4, Marvel Age Spider-Man Team-Up (2004) #5, Uncanny X-Men (1981) #265-266; material from Uncanny X-Men: First Class Giant-Size Special (2009) #1, Black Panther (2018) #23. A history lesson you won't want to miss! The back alleys of Cairo's "Thieves' Quarter" are no place for a child to grow up - unless that child is destined to be one of Marvel's greatest heroes! Long before she became the X-Man known as Storm, a young orphan named Ororo Munroe prowled the streets of Cairo, a pickpocket trained by a master thief. But when the opportunity of a lifetime arises, get ready for awesome Egyptian adventure as Ororo leads her fellow street urchins into…the tomb of Ozymandias! Plus: more tales of Storm's early days as a hero, including team-ups with Jean Grey and Spider-Man - and her first meeting with Gambit!

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Page Count

224

Publisher

Marvel Entertainment

Published Date

ISBN 10

1302940678

ISBN 13

9781302940676

Rheumatology

By: Marc C. Hochberg,Alan J. Silman,Josef S. Smolen,Michael E. Weinblatt,Michael H. Weisman

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Rheumatology

By: Marc C. Hochberg,Alan J. Silman,Josef S. Smolen,Michael E. Weinblatt,Michael H. Weisman

Consistently lauded for its comprehensiveness and full-color color presentation, the latest edition of Rheumatology by Marc C. Hochberg, MD, MPH et al. continues the tradition of excellence of previous editions. Designed to meet the needs of the practicing clinician, it provides extensive, authoritative coverage of rheumatic disease from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format covering all major disorders of the musculoskeletal system in complete, self-contained chapters. Get trusted perspectives and insights from chapters co-authored by internationally renowned leaders in the field, 25% of whom are new to this edition. Track disease progression and treat patients more effectively with the most current information, including 22 new chapters on genetic findings, imaging outcomes, and cell and biologic therapies as well as rheumatoid arthritis and SLE. Incorporate the latest findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics.

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11248

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323086322

ISBN 13

9780323086325

Handbook of Veterinary Neurology - E-Book

By: Michael D. Lorenz,Joan Coates,Marc Kent

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Handbook of Veterinary Neurology - E-Book

By: Michael D. Lorenz,Joan Coates,Marc Kent

Handbook of Veterinary Neurology provides quick access to vital information on neurologic conditions in a wide range of species, including canine, feline, bovine, caprine, equine, ovine, and porcine. A problem-oriented approach makes it easy to diagnose and treat neurologic problems in small and large animals. The coverage of disorders by problem, not by established disease diagnosis, emulates how animals present to the veterinary hospital and simplifies the formulation of a correct diagnosis. Within each chapter, discussions of neurologic disease include a review of the localization criteria and the diseases that can cause that problem, plus treatment and surgical techniques. Lead author Michael D. Lorenz brings decades of experience to neurologic assessment, using a diagnostic approach that requires minimal knowledge of neuroanatomy. - A problem-based approach is organized by presenting sign rather than by condition, guiding you to logical conclusions regarding diagnosis and treatment. - Algorithms diagram the logic necessary to localize lesions and to formulate diagnostic plans. - Coverage of current diagnostic techniques includes the use of diagnostic tools, such as radiology, spinal fluid analysis, electrodiagnosis, and MR imaging. - Case histories in each chapter present a problem and the results of the neurologic examination, then ask you to solve the problem by localizing the lesion, listing probable causes, and making a diagnostic plan. Answers are provided at the back of the book. - A consistent format for each case history includes signalment, history, physical examination findings, and neurologic examination. - A comprehensive appendix describes species and breeds that have a congenital predisposition for particular neurologic diseases. - Extensive references make it easy to pursue in-depth research of more advanced topics. - A companion website includes 20 narrated video clips with accompanying PowerPoint slides that correlate to the case histories in the book, covering neurologic assessment and clinical problems such as paresis of one limb, tetraparesis, stupor, seizures, ataxia of the head and limbs, and cranial nerve disorders. - Two new co-authors, Jean Coates and Marc Kent, board-certified in neurology, enhance the credibility of this edition. - A full-color design and numerous illustrations include enhanced images of neuroanatomy and pathology.

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562

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

1437706525

ISBN 13

9781437706529

Procedural Dermatology

By: Marc Avram,Mathew Avram,Desiree Ratner

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Procedural Dermatology

By: Marc Avram,Mathew Avram,Desiree Ratner

Learn how to perform basic and advanced skin surgery with this combination text and atlas Written in clear, concise language, and backed by thel atest evidence, Procedural Dermatology is a practical guide for performing all types of skin procedures for both medical and cosmetic problems. Procedural Dermatology opens with a section on Surgical Principles, that discusses essentials such as headand neck anatomy, preoperative evaluation, anesthesia, aseptic technique, antibiotics, wound healing, and postoperative care. The next four sections (Surgical Skills, Skin Tumors, Aesthetic & Laser Procedures, and Aesthetic Problems) cover the different types of surgical procedures, describing them in step-by-step fashion, with each step illustrated with line drawings and photographs. Procedural Dermatology compiles current, state-of-the-art information valuable to all practitioners of dermatologic surgery, from the trainees to seasoned surgeons wishing to refine their skills.

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Page Count

732

Publisher

McGraw Hill Professional

Published Date

ISBN 10

0071802525

ISBN 13

9780071802529

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