A magnificent city lost over time destroyed by the Gods and sent to the bottom of the Ocean forever later to be written by the Greek philosopher Plato in two dialogues. Destroyed was their home but not its people who rebuilt their city back to its former glory. Learning from their violent past not to repeat it, the centuries go by and the outside world has populated the surface, no place for the Atlantean people to call home. Safe from the outside world and their advanced technology that is generated by a rare element only found at the outer reaches of the solar system. The Atlanteans decide to stay below the waves to watch over and nurture the people from above giving them technology through the centuries until they are ready to accept them and their technology. Creating another city on the other side of Earth deep below the Pacific Ocean, the city grows rapidly hungry for more energy and power, the people in time rebel against Atlantis. With all-out war looming over the peaceful people of Atlantis, one man not from their world will come to understand the past and his future.
Networks provide a very useful way to describe a wide range of different data types in biology, physics and elsewhere. Apart from providing a convenient tool to visualize highly dependent data, networks allow stringent mathematical and statistical analysis. In recent years, much progress has been achieved to interpret various types of biological network data such as transcriptomic, metabolomic and protein interaction data as well as epidemiological data. Of particular interest is to understand the organization, complexity and dynamics of biological networks and how these are influenced by network evolution and functionality. This book reviews and explores statistical, mathematical and evolutionary theory and tools in the understanding of biological networks. The book is divided into comprehensive and self-contained chapters, each of which focuses on an important biological network type, explains concepts and theory and illustrates how these can be used to obtain insight into biologically relevant processes and questions. There are chapters covering metabolic, transcriptomic, protein interaction and epidemiological networks as well as chapters that deal with theoretical and conceptual material. The authors, who contribute to the book, are active, highly regarded and well-known in the network community.
Neurodevelopmental disabilities are a common problem in child health. This book takes a comprehensive approach to addressing these often challenging clinical diagnoses. In particular, it focuses on the two most common of childhood neurodevelopmental disabilities: global developmental delay and developmental language impairment. It seeks to put forward our present conceptualization of these entities as well as their proper evaluation and assessment and diagnosis from a variety of perspectives. It also provides details on our current understanding of the scientific basis of these disorders and their underlying causes. Issues related to medical management, rehabilitation, and eventual outcomes are also addressed in a detailed way. The book has wide appeal to those in paediatrics, developmental paediatrics, child neurology, and paediatric rehabilitation. Its geographic appeal includes both developed and developing nations as some chapters are devoted to the particular issues faced in underdeveloped countries. The book’s focus on both clinical and scientific aspects is invaluable in this field. It also provides extensive information in a single source relating to often-overlooked areas such as medical management, rehabilitation, public policy, and ethics.
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