The diagnosis of myelodysplastic syndromes (MDS), a heterogeneous group of clonal hematopoietic disorders, is being made with increasing frequency over the past decade owing to increased recognition, improved understanding, and an aging population. This book, completely updated since the first edition, summarizes in a concise and focused way the current knowledge of all aspects of MDS. Clinical presentation, etiology, epidemiology, molecular biology, classification, and staging are all discussed. Clear guidance is provided on diagnosis and differential diagnosis, and treatment strategies are explained in detail, including administration of hematopoietic growth factors, biologically based treatment, hematopoietic stem cell transplantation, and supportive care. Additional chapter is devoted to MDS in children. This practically oriented book will be of value to a broad spectrum of students and practitioners in the field.
With the 13th edition, Wintrobe’s Clinical Hematology once again bridges the gap between the clinical practice of hematology and the basic foundations of science. Broken down into eight parts, this book provides readers with a comprehensive overview of: Laboratory Hematology, The Normal Hematologic System, Transfusion Medicine, Disorders of Red Cells, Hemostasis and Coagulation; Benign Disorders of Leukocytes, The Spleen and/or Immunoglobulins; Hematologic Malignancies, and Transplantation. Within these sections, there is a heavy focus on the morphological exam of the peripheral blood smear, bone marrow, lymph nodes, and other tissues. With the knowledge about gene therapy and immunotherapy expanding, new, up-to-date information about the process and application of these therapies is included. Likewise, the editors have completely revised material on stem cell transplantation in regards to both malignant and benign disorders, graft versus host disease, and the importance of long-term follow-up of transplantation survivors.
The Third Edition of Knowles Neoplastic Hematopathology has been thoroughly updated by the world's experts to cover all aspects of neoplastic hematopathology, a field that covers disorders of the bone marrow, spleen, and lymphatic system. Now in full-color, this completely revised and expanded edition integrates the basic science, modern diagnostic techniques, and clinical aspects of malignant diseases affecting these organs. It is the most comprehensive, encyclopedic textbook concerning neoplastic hematopathology available on the market today.
Covering the broad range of benign and malignant disorders that affect the hematopoietic system, Hematopathology, 3rd Edition, remains your #1 source of authoritative information in this fast-changing field. Edited by Dr. Elaine Jaffe and a team of globally renowned, expert co-editors, it offers a wealth of up-to-date information in an easily accessible format, equipping you to deliver more accurate and actionable pathology reports. Comprehensive in scope, this highly illustrated, practical text is a must-have resource for residents and practicing pathologists alike. - Helps you navigate the latest changes in the classification of hematolymphoid neoplasms, providing guidance for use of both the International Consensus Classification (ICC) and 5th edition of the WHO classification. - Incorporates the latest molecular/cytogenetic information, regarding newly recognized entities and the latest diagnostic criteria. - Provides you with today's most effective guidance in evaluating specimens from the lymph nodes, bone marrow, peripheral blood, and more, with authoritative information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each. - Details the latest insights on the molecular biology of benign and malignant hematologic disorders. - Features more than 1,100 high-quality color images that mirror the findings you encounter in practice. - Uses an easy-to-navigate, templated format with standard headings in each chapter. - Includes information on disease progression and prognosis, helping you better understand the clinical implications of diagnosis. - Shares the knowledge and expertise of new editors, Drs. Lisa Rimsza, Attilio Orazi, and Steven Swerdlow, providing expertise in molecular diagnostics, bone marrow and lymph node biopsies.
Authoritative, hands-on desk reference for the practicing oncologist—from the leader in the field of cancer management and treatment A Doody's Core Title for 2019! The MD Anderson Manual of Medical Oncology details the personalized multidisciplinary approach to cancer management and treatment of common and rare cancers pioneered by The University of Texas MD Anderson Cancer Center. Its pragmatic presentation can provide valuable insights at any stage of your career. This completely updated third edition reflects the most recent advancements, including expanded coverage of the rapidly evolving area of biological and immune therapies of cancer, many developed at MD Anderson. It emphasizes and discusses continuing developments in diagnostic procedures, which include the incorporation of new molecular markers and revised staging systems. It also reinforces how imaging and molecular profiling can prevent administration of overly aggressive, toxic treatment regimens or invasive surgery to treat superficial or indolent tumors. To help you quickly assess cancer management options, every chapter includes numerous tables, diagrams, imaging photographs, and prescriptive advice. Evidence-based treatment algorithms in the form of flowcharts and diagrams shaped by the clinical experience of MD Anderson’s world-class faculty enhance the text. The third edition features important new chapters on key topics such as: · Pediatric Cancers · Molecular Biomarkers and Cancer · Immuno-Oncology · Targeted Therapies in Cancer · Onco-Cardiology · Pulmonary Complications of Cancer Therapy · Applied Biostatistics Offering the perfect balance of narrative text, summary tables, and clinical photographs (many in full color), there is truly not a more accessible, up-to-date, or authoritative clinician’s guide to the medical management of patients with cancer and its complications than The MD Anderson Manual of Medical Oncology.
The second edition of Primary Immunodeficiency Diseases presents discussions of gene identification, mutation detection, and clinical and research applications for over 100 genetic immune disorders--disorders featuring an increased susceptibility to infections and, in certain conditions, an icreased rate of malignancies and autoimmune disorders. Since the publication of the first edition, a flurry of new disease entities has been defined and new treatment regimens have been introduced, the most spectacular being successful treatment by gene therapy for two genotypes of combined immunodeficiency. The first edition marked a historic turning point in the field of immunodeficiencies, demonstrating that many of the disorders of the immune systam could be understood at a molecular level. This new edition can proudly document the tremendous pace of progress in dissecting the complex immunologic networks responsible for protecting individuals from these disorders.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2020! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.
This issue of Medical Clinics of North America, guest edited by Roy Colven, MD, is devoted to Dermatology. Articles in this issue include: Topical Therapy Primer for the Non-dermatologist; The Role of Biologic Therapies in Dermatology; Commonly Used Non-biologic Systemic Therapies in Dermatology; Diseases of Skin Appendages: Acne, Alopecia, and Hyperhidrosis; Common Procedures in Dermatology; Skin Cancer Epidemiology, Detection, and Management; Psoriasis and Cardiovascular Disease; Cutaneous Adverse Drug Reactions; Consultative Inpatient Dermatology; Approach to the Patient with Diffuse Blisters; Teledermatology; Nail Disease for the Primary Care Provider; Rheumatologic Skin Disease; and Common Pediatric Skin Diseases.
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