Building from general principles, the authors clearly explain the fundamental role of epithelia in plasma electrolyte and water balance. Emphasis is placed on experimental approaches and methodology. A comprehensive glossary of terms is included.
Vitamins are a group of physiologically very important, chemically quite complex organic compounds, that are essential for humans and animals. Some vitamins and other growth factors behave as antioxidants, while some can be considered as biopigments. As their chemical synthesis is laborious, their biotechnology-based synthesis and production via microbial fermentation has gained substantial interest within the last decades. Recent progress in microbial genetics and in metabolic engineering and implementation of innovative bioprocess technology has led to a biotechnology-based industrial production of many vitamins and related compounds. Divided into three sections, this volume covers: 1. water-soluble vitamins 2. fat-soluble vitamin compounds and 3. other growth factors, biopigments, and antioxidants. They are all reviewed systematically: from natural occurrence and assays, via biosynthesis, strain development, to industrially-employed biotechnological syntheses and applications.
The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel approaches to drug screening and therapeutic drug targeting to help inform future avenues of drug research. Highly topical, this accessible edited volume features chapters contributed by respected experts from around the globe. The book helps postgraduate students and professional scientists working in academia and industry understand the molecular mechanisms of pharmacology, current pharmacological knowledge, and future perspectives in drug discovery, focusing on important biochemical protein targets and drug targeting strategies for specific diseases. Examining the pharmacology of therapeutically undefined targets and their potential applications, it includes chapters on traditional therapeutic targets, including enzymes (phosphodiesterases and proteases), ion channels, and G protein-coupled receptors, as well as more recently identified avenues of exploration, such as lipids, nuclear receptors, gene promoters, and more. Since different diseases require different targeting techniques, the book also includes dedicated chapters on strategies for investigating Alzheimer's, diabetes, pain, and inflammation treatments. Concluding with a cross-sectional look at new approaches in drug screening, Therapeutic Targets is an invaluable resource for understanding where the next generation of drugs are likely to emerge.
The definitive guide to sonography in obstetrics and gynecology—thoroughly updated and enhanced by the addition of teaching cases Doody's Core Titles for 2021! This acclaimed guide is a clinically relevant reference text, an atlas, and a teaching/learning resource. Presented in full color and enriched by more than 2,000 illustrations, it expertly examines the full spectrum of disorders and conditions likely to be encountered in gynecologic and maternal-fetal care. You will find expert, all-inclusive coverage of everything from sonographic operating instruments and screening the fetal patient for syndromes and anomalies, to diagnosing the female patient for cysts, infertility, and incontinence. This edition has been updated to include coverage of the latest procedures and diagnostic guidelines for the use of sonography in ob/gyn, including 3D and 4D US and enhanced image processing, contrast enhanced sonography, ultrasound guided fetal therapy, sonographic evaluation of pelvic pain, and much more. The Eighth Edition also features an extensive series of teaching cases. Each case consists of the patient’s medical history, representative US images, cineloop videos, Q&A, and teaching points with references. Fleischer’s Sonography in Obstetrics & Gynecology, Eighth Edition opens with general obstetric sonography, covering such pivotal topics as normal pelvic anatomy and fetal echocardiography, before moving into fetal anomalies and disorders. Risk assessment and therapy, including first trimester screening and amniocentesis, are explored in the next section, while the remaining parts of the book focus on maternal disorders, gynecologic sonography, and the newest complementary imaging modalities.
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