Natural products have played a pivotal role in antibiotic drug discovery, with most anti-infective drugs being derived from natural products or natural product leads. However, the rapid onset of resistance to most anti-infective drugs considerably diminishes their effectiveness and requires a constant supply of new drugs for the effective treatment of infections. Infectious diseases account for a third of all deaths worldwide. The spread of multidrug-resistant strains of bacteria makes it necessary to identify new classes of antibacterials and compounds that inhibit these resistance mechanisms. Numerous members of the Asteraceae family are important as cut flowers and ornamental crops, as well as being medicinal and aromatic plants, many of which produce essential oils used in folk and modern medicine and in the cosmetics and pharmaceutical industries. Essential oils generally have a broad spectrum of bioactivity, owing to the presence of several active ingredients (e.g., terpenes and phenol-derived aromatic and aliphatic components) that have various modes of action. Extensive studies of the chemical components of Asteraceae species have led to the identification of many substances, including essentials oils, with interesting antibacterial activity. This review summarizes some of the main reports on the chemistry and antibacterial activity of Asteraceae essential oils in the recent literature (2005 to May 2012).
For more than a century, directors from both sides of the border have chosen Mexico as the location to create their cinematic art, leaving an indelible imprint on the imaginations of moviegoers and filmmakers worldwide. Now, for the first time, Made in Mexico: Hollywood South of the Border presents a comprehensive examination of more than one hundred Hollywood theatrical feature films made in Mexico between 1914 and the present day. Lavishly illustrated throughout, Made in Mexico examines how Hollywood films depicted Mexico and how Mexico represented itself in relation to the films shot on location. It pulls back the curtain on how Hollywood filmmakers influenced Mexican films and Mexican filmmakers influenced Hollywood. Listed chronologically and featuring cast, credits, synopsis, and contemporary reviews along with a production history for each entry, this book highlights the concept of “crossing borders ” in which artists from both nations collaborated with one another. Made in Mexico also provides a brief historical perspective on the aesthetics, economics, and politics of the film industries in each country, giving readers a glimpse of the external forces at play in the production of these films. With motion pictures permeating the cultural and historical landscape of both Mexico and the United States, this compulsively readable compendium demonstrates the far-reaching influences of the featured films on the popular culture of both nations.
Offering deep insight to the lives of human rights activists in a conflict zone, against the backdrop of major historical changes that shaped Latin America in the twentieth century, this book illuminates the critical role of human rights organizations in bringing violence to public attention and analyzing its causes and consequences.
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