Lisbeth Illum's Books

Delivery Systems for Peptide Drugs

By: S.S. Davis,Lisbeth Illum,E. Tomlinson

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Delivery Systems for Peptide Drugs

By: S.S. Davis,Lisbeth Illum,E. Tomlinson

Recent years have seen enormous advances in the field of protein and peptide engineering and a greater understanding in the way in which biological response modifiers function in the body. It is now possible through the use of recombinant DNA techniques, or by solid phase protein synthesis, to produce significant quantities of a wide variety of regulatory agents that are therapeutically applicable. The list of these response modifiers expands almost daily to include interferons, macrophage activation factors, neuropeptides and agents that may have potential in cardiovascular disease, inflammation, contraception etc. Prospects to use some of these materials in medicine have reached the stage where products have either been approved by regulatory authorities or are the subject of applications as investigatory drugs or as new therapeutic agents. In some uses the pertinent agent will be administered on an acute basis in the form of a simple injection, as, for example, the use of a tissue plasminogen activator for the treatment of coronary infarct. In other cases regulatory proteins and peptides are indicated for chronic therapy and here they will need to be administered by an appropriate delivery system. Unfortunately, the research on delivery systems for peptides and proteins has not kept pace with the rapid progress in biotechnology and, consequently, there are presently few systems that are entirely appropriate for the administration of macromolecular drugs according to complex dosage regimens, (eg intermittent and pulsed therapy). Furthermore essential pharmacokinetic and pharmacodynamic data may be missing.

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363

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1475799608

ISBN 13

9781475799606

Pablo Tac, Indigenous Scholar

Writing on Luiseño Language and Colonial History, C.1840

By: Lisbeth Haas

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Pablo Tac, Indigenous Scholar

Writing on Luiseño Language and Colonial History, C.1840

By: Lisbeth Haas

“Pablo Tac's life was both tragic and victorious, and his experiences echo down through the years, offering the light of understanding to us in our world today. A thought-provoking book and a must-read for students of indigenous California.” —Ernest Siva, author of Voices of the Flute: Songs of Three Southern California Indian Nations "This is an exceptional piece of research and the definitive work on Pablo Tac. For the first time the entire corpus of the known writings of this ground-breaking Native Californian scholar are presented without editing, in their original languages (Latin, Luiseño) and in English translation. Lisbeth Haas presents a lucid and insightful account on the life, times, and significance of this important figure, while James Luna provides provocative commentary and striking images about Indian life today in the footsteps of Pablo Tac. This book belongs in the library of anyone interested in California history, Native Californians, and the Franciscan missions." —Kent Lightfoot, author of Indians, Missionaries, and Merchants: The Legacy of Colonial Encounters on the California Frontiers “Lisbeth Haas must be praised for gathering an exceptional team of scholars for the transcription, editing, and translation of Pablo Tac's Luiseño grammar, dictionary, and history. Haas's introductory essay situates Tac in a global context, defined by the fellow students Tac found in Rome in the 1830s while studying for the priesthood. Performance artist James Luna complements Haas's lucid assessment of Tac's brilliance as an indigenous scholar with a verbal and visual testimony of shared struggles as cultural warriors.” —José Rabasa, author of Without History: Subaltern Studies, the Zapatista Insurgency, and the Specter of History “The important manuscripts of the young nineteenth-century Luiseño scholar Pablo Tac are available at last to the American public, and most importantly to the people of Tac’s homeland. This faithful representation and translation of his work is fascinating in its own right, and enriched further by the insightful introductions by scholar Lisbeth Haas and Luiseño artist and wordsmith James Luna. Tac interweaves his masterful linguistic description and unfinished dictionary of nineteenth-century Luiseño with an illuminating account of Luiseño life and history before and during the mission era. Haas provides an equally interesting description of the scholarly and political environment of Rome where Tac lived, learned, and created from 1834 to 1841. Luna’s introduction and a foreword by the Luiseño tribal chair bring a twenty-first century indigenous interpretation to Tac’s long-ago life and work. Yet there is a freshness to Tac’s writing that is ageless, and makes us wish we could learn even more about this talented young man who participated in so many worlds, and whose life and career were too short.” —Leanne Hinton, author of Flutes of Fire: Essays on California Indian Languages

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Page Count

288

Publisher

Univ of California Press

Published Date

ISBN 10

0520261895

ISBN 13

9780520261891

Delivery Systems for Peptide Drugs

By: S.S. Davis,Lisbeth Illum,E. Tomlinson

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Delivery Systems for Peptide Drugs

By: S.S. Davis,Lisbeth Illum,E. Tomlinson

Average ratings

N/A

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Solve jigsaw puzzle

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363

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1475799608

ISBN 13

9781475799606

Transmucosal Absorption Enhancers in the Drug Delivery Field

By: Lisbeth Illum,Sam Maher,Luca Casettari

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Transmucosal Absorption Enhancers in the Drug Delivery Field

By: Lisbeth Illum,Sam Maher,Luca Casettari

Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on permeation enhancers (PEs) that have a history of safe use in man. This Special Issue entitled “Transmucosal Absorption Enhancers in the Drug Delivery Field” aims to present the current state-of-the-art in the application of PEs to improve drug absorption. Emphasis is placed on identification of novel permeation enhancers, mechanisms of barrier alteration, physicochemical properties of PEs that contribute to optimal enhancement action, new delivery models to assess PEs, studies assessing safety of PEs, approaches to assist translation of PEs into effective oral, nasal, ocular and vaginal dosage forms and combining PEs with other delivery strategies.

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406

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ISBN 10

3039218492

ISBN 13

9783039218493

Book's by Lisbeth Illum

Delivery Systems for Peptide Drugs

Delivery Systems for Peptide Drugs

Pablo Tac, Indigenous Scholar

Pablo Tac, Indigenous Scholar

Delivery Systems for Peptide Drugs

Delivery Systems for Peptide Drugs

Transmucosal Absorption Enhancers in the Drug Delivery Field

Transmucosal Absorption Enhancers in the Drug Delivery Field

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