Platelets are fragments of blood cells that occur in the blood of vertebrates and are associated with blood clotting. Scientists have made great strides in recent years in understanding what stimulates platelets to form blood clots at the molecular level and in developing drugs to inhibit platelet action. Their work has a direct effect on millions of people who deal with cardiovascular disease, strokes, surgery, physical trauma, and other conditions. While references to platelet function have been included in some large texts, there has not been a basic reference manual that researchers and clinicians can use in their daily work until now.Platelet Protocols fills the need for a straightforward and comprehensive laboratory manual on current procedures for evaluating and analyzing platelet function and abnormalities. It is an easy-to-read, understandable resource which can be kept at the bench and referred to frequently by scientists, clinicians, and laboratory staff involved in platelet related areas. Topics range from the basics of anticoagulants to the latest developments in platelet testing.Includes: - A basic introduction to platelet anatomy and physiology - Testing procedures for new anti-platelet therapies - Descriptions of platelet function abnormalities - Therapeutic approaches to inhibition of platelet function - Step-by-step methodologies with clear explanations - Helpful appendixes of recipes, instructions, sources of reagents, and more
Clinical Neuroscience offers a comprehensive overview of the biological bases of major psychological and psychiatric disorders, and provides foundational information regarding the anatomical and physiological principles of brain functioning. In addition, the book presents information concerning neuroplasticity, pharmacology, brain imaging, and brain stimulation techniques. Subsequent chapters address specific psychological disorders and neurodegenerative diseases, including major depressive and bipolar disorders, anxiety, schizophrenia, disorders of childhood origin, and addiction, as well as neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases. This highly readable textbook expands case examples and illustrations to discuss the latest research findings in clinical neuroscience from an empirical, interdisciplinary perspective.
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