World famous at twenty-four, brilliant and reckless, hard-living and scandalous, Stephen Crane wrote The Red Badge of Courage before he ever experienced war first-hand. So true was his portrait of a young man who runs from his first confrontation with battle that Civil War veterans argued about whose regiment Crane had been in. Considered by H.G. Wells as “beyond dispute, the best writer of our generation,” Crane was also famous in his time as an unforgettable personality, an Adonis with tawny hair and gray-blue eyes that Willa Cather described as “full of luster and changing lights.” A lover of women and truth at any cost, Crane, in his short life, paid dearly for both. He alienated the New York police when he testified against a policeman on behalf of a prostitute falsely accused of soliciting, forcing him to live the rest of his short life as an expatriate in England. Reporting on the Spanish American War, Crane described the Rough Riders blundering into a trap after arriving in Cuba, infuriating Roosevelt. He died tragically young, leaving behind a handful of fine short stories, including The Open Boat and The Blue Hotel, along with war reporting, novels, and poetry.
The Addams Family is creepy and kooky, but wait till you see what their creator had in his apartment. In Charles Addams: A Cartoonist’s Life, meet the legendary cartoonist behind the altogether ooky Addams Family in this first biography, written with exclusive access to Charles Addams’s private archives. Take a front-row seat to the widespread rumors and storytelling genius behind one of America’s oddest and most iconic creators. Even as The Addams Family grew in fame, the life of Charles Addams remained shrouded in mystery. Did he really sleep in a coffin and drink martinis garnished with eyeballs? In reality, Addams himself was charismatic and spellbinding as the characters he created. Discover the real stories behind Addams’s most famous, and most private drawings, including the cartoon that offended the Nazis. From his dazzling love for sports cars and beautiful women—Jackie Kennedy and Joan Fontaine among them—to the darkest relationship of his life, this witty book reveals Addams’s life as never before. With rare family photographs, previously published cartoons, and private drawings seen here for the first time, Linda H. Davis provides a fascinating journey into the life of a beloved American icon.
In the first section of Volume 2, toxicological factors affecting nutritional status are discussed. Medications and alcohol may affect nutritional status. Section 2 provides a discussion of nutrition-related diseases which occur more frequently among the elderly. Cardiovascular diseases including coronary heart disease and cerebrovascular disease are the leading causes of death in the U.S. The relative importance of cardiovascular diseases, in terms of all deaths for the given age group, rises steadily with age. The death rate from these diseases is 28% for the middle age group (35 to 44) and is 69% for the old age group (age 75 and above. This reflects the continued progression of artherosclerosis with aging. Cancer is the second leading cause of death in the U.S. The death rate from cancer also rises steadily with age. The death rate from diabetes mellitus increases progressively with age and more rapidly after the age of 45. The incidence of diabetes mellitus is 0.23% under age 25 and 6.2% over 45.
Edited and written by true leaders in the field, Psychopathology provides comprehensive coverage of adult psychopathology, including an overview of the topic in the context of the DSM. Individual chapters cover the history, theory, and assessment of Axis I and Axis II adult disorders such as panic disorder, social anxiety, bipolar disorders, schizophrenia, and borderline personality disorder.
Now in its Fifth Edition, America and Its Peoples presents American history filled with the drama and conflict that holds the attention of all students. Social history-with an emphasis on sports, leisure, and popular culture-is effectively integrated with more traditional coverage of military history, politics, and diplomacy. This edition highlights the rich ethnic diversity of the American people with vivid character sketches, colorful anecdotes, primary sources, new pedagogy, and a spirited narrative.
Neuroscience's inherent complexity and rapid growth mean that no one can keep abreast of all the changes across the field. We each bring a necessarily narrow perspective. Neurotherapeutics: Emerg ing Strategies is an attempt to provide some diverse perspectives within the hunt for new drugs to treat central nervous system diseases. The book's premise is that the search for new drugs is based on an understanding ofboth clinical and basic sciences. Neurotherapeu tics: Emerging Strategies begins with psychiatry and concludes with neurological disorders. Each chapter examines a disease, including clinical features and existing treatments, but the emphasis is on current concepts of underlying causes and novel strategies for drug discovery arising from these possible mechanisms. Participating authors include basic neuroscientists, industry-based pharmacolo gists and chemists, and clinicians. The chapters describe the status of the existing disease treat ments, and when treatments are lacking, the approach is more basic science oriented. When there is a long history of treatment, there is greater emphasis on those therapies. However, all the chapters seem to reflect the benefits of cloning, since the availability of receptor subtypes now promises the opportunity for greater specificity of drug effects. Modulation of second messengers is another new and recur ring theme. And in the chapter on cachexia, cytokines are explored both as drugs and drug targets. Neurotherapeutics: Emerging Strategies reflects the complex ity of the nervous system, but the overriding message is hope for new and better drugs to treat those diseases that rob us of ourselves.
Trust a librarian to help you find books you’ll want to read Library Lin’s Curated Collection of Superlative Nonfiction is a librarian’s A-list of nonfiction books organized by subject area—just like a library. Linda Maxie (Library Lin) combed through 65 best books lists going back a century. She reviewed tens of thousands of books, sorted them according to the Dewey Decimal Classification system, and selected an entire library’s worth for you to browse without leaving home. Here you’ll find • Summaries of outstanding titles in every subject • Suggestions for locating reading material specific to your needs and interests In this broad survey of all the nonfiction categories, you will find titles on everything from the A-bomb to Zen Buddhism. You might find yourself immersed in whole subject areas that you never thought you’d be interested in.
1. 1 SCOPE OF BOOK n explosion of novel findings in the past decade has contrib A uted to the great progress toward understanding the biology of human cancers. Much of this progress can be attributed to our abil ity to dissect many biological processes at the molecular level. Most spectacular is the technology of molecular biology that allows identi fication and characterization of genes that participate in the genesis of human cancers. Three major groups of genes appear to play out the drama of cancer development: tumor suppressor genes, mis match repair genes, and oncogenes. The tumor suppressor genes 1 encode products that are inhibitory to cell proliferation. The loss of these inhibitors, by mutation or deletion, can unleash cells from their restraints to proliferate. Mutations in the mismatch repair 2 10 genes also have been implicated in tumorigenesis. - The inability of cells to repair spontaneously occurring mutations leads to genom ic instability and could potentially result in the accumulation of car cinogenic DNA lesions. Finally, activation of proto-oncogenes, which are normal cellular genes, into oncogenes could accelerate the 11 processes of cell proliferation. c-myc was one of the very first proto oncogenes to be identified and because it normally plays pivotal roles in both cell proliferation and cell death has enticed many to investigate the molecular mechanisms by which it transforms cells.
Early Icons and Landmarks As western migration came to the Colorado frontier, forts were established to protect the settlers. These forts were intertwined with the lives of the frontiersmen. Scout Thomas Tate Tobin oversaw the workers who built the adobe fortress known as Fort Garland. Here, Tobin delivered the heads of the murderous Espinosas gang to Colonel Sam Tappan. Fort Sedgwick, originally known as Camp Rankin, was attacked by the Cheyenne Dog soldiers, including George Bent. Fort Lyon, an expanded fortress of William Bent's third fort, became the staging point for Colonel John M. Chivington's march to Sand Creek where peaceful Cheyenne were murdered. Later, Christopher "Kit" Carson died in the fort's chapel. Legendary Jim Beckwourth was associated with both Fort Vasquez and Fort Pueblo. Author Linda Wommack revisits the glory and the mistakes of the frontiersmen who defined Colorado and the forts that dotted the wild landscape.
World famous at twenty-four, brilliant and reckless, hard-living and scandalous, Stephen Crane wrote The Red Badge of Courage before he ever experienced war first-hand. So true was his portrait of a young man who runs from his first confrontation with battle that Civil War veterans argued about whose regiment Crane had been in. Considered by H.G. Wells as “beyond dispute, the best writer of our generation,” Crane was also famous in his time as an unforgettable personality, an Adonis with tawny hair and gray-blue eyes that Willa Cather described as “full of luster and changing lights.” A lover of women and truth at any cost, Crane, in his short life, paid dearly for both. He alienated the New York police when he testified against a policeman on behalf of a prostitute falsely accused of soliciting, forcing him to live the rest of his short life as an expatriate in England. Reporting on the Spanish American War, Crane described the Rough Riders blundering into a trap after arriving in Cuba, infuriating Roosevelt. He died tragically young, leaving behind a handful of fine short stories, including The Open Boat and The Blue Hotel, along with war reporting, novels, and poetry.
In this first biography of the rest cartoonist, Charles Addams, written with exclusive access to Addam's intimates and his private papers, we finally meet the man behind the fames cartoons and circling rumors. Here is his surprising childhood in New Jersey, the cartoon that offended the nazis, the friend whose early death Addams long mourned. Here are his wives, the stories behind his most famous--and some of his most private--cartoons, and the Addams whom even his closest friends didn't know. With wit, humor, poignancy, and insight--enhanced by rare family photographs, classic and previously unpublished cartoons, and private drawings--Linda H. Davis paints an engaging and endearing portrait of a marvelous American original.
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